Abingem-1000 mg Injection (Gemcitabine 1000mg/Vial)
Composition: Gemcitabine (1000mg)
Dosage Form: Injection | Route of Administration: Parenteral
Packaging: Single-Dose Vial
Product Overview
Abingem-1000 mg Injection is a cytotoxic (anti-cancer) medication used either alone or in combination with other chemotherapy agents to treat a wide range of solid tumors, including breast, pancreatic, non-small cell lung, ovarian, and bladder cancers.
The active ingredient, Gemcitabine, is a nucleoside analog that inhibits DNA synthesis in rapidly dividing cancer cells, leading to cell death and suppression of tumor growth. Abingem is widely recognized in oncology for its efficacy and safety profile in systemic cancer therapy.
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Mechanism of Action
Gemcitabine works by interfering with DNA replication within cancer cells. Once incorporated into the DNA strands during cell division, it halts further synthesis and triggers programmed cell death (apoptosis). This mechanism effectively prevents cancer cells from multiplying, thereby slowing disease progression.
Therapeutic Indications
Abingem-1000 mg Injection is indicated for the treatment of:
Breast Cancer
Pancreatic Cancer
Non-Small Cell Lung Cancer (NSCLC)
Ovarian Cancer
Urinary Bladder Cancer
It is often prescribed either as monotherapy or in combination with platinum-based agents (e.g., cisplatin) for enhanced efficacy.
Dosage and Administration
The dosage is determined by an oncologist based on body surface area (BSA), cancer type, and response to therapy.
Administered intravenously under the supervision of qualified healthcare professionals.
Do not self-administer this medication.
Possible Side Effects
Common side effects may include:
Nausea or vomiting
Hair loss (alopecia)
Skin rash or itching
Fatigue or weakness
Injection site reactions
Swelling (edema)
Low white blood cell count (neutropenia)
Low platelet count (thrombocytopenia)
Reduced bone marrow activity
Seek immediate medical attention for severe symptoms such as persistent fever, unusual bleeding or bruising, difficulty breathing, or severe allergic reactions.
Precautions & Warnings
Contraindicated in patients with known hypersensitivity to Gemcitabine.
Use with caution in patients with kidney, liver, or heart disorders.
Avoid during pregnancy and breastfeeding unless absolutely necessary.
Men should discuss sperm preservation before starting treatment, as Gemcitabine may affect fertility.
Avoid alcohol consumption during therapy.
Inform your doctor of any history of radiotherapy, recent vaccinations, or infections before treatment.
Storage
Store in a cool, dry place at a temperature between 10°C and 25°C (not exceeding 30°C).
Protect from light and moisture.
Keep out of reach of children.
Overdose Management
Since Abingem-1000 mg Injection is administered by a medical professional, overdose is unlikely. However, symptoms of overdose may include severe rash, unusual bleeding, extreme fatigue, or signs of infection. Immediate medical attention is required in such cases.
Key Highlights
Premium-quality Gemcitabine Injection
Effective against multiple solid tumors
Broad-spectrum cytotoxic agent used in global oncology protocols
Administered under expert medical supervision
GMP compliant manufacturing standards
