Medroxy 150 (Medroxyprogesterone Acetate) Injection: Verified Pharmaceutical Exporter from India | Bulk Supplier for USA, UK, Australia, Thailand, Singapore & Jamaica

Product Profile: Medroxy 150 (Medroxyprogesterone Acetate 150mg/ml)

Medroxy 150 is a sterile, aqueous injectable suspension containing Medroxyprogesterone Acetate (MPA), a potent synthetic progestogen. It serves as a highly effective, long-acting depot contraceptive administered via intramuscular injection.

1. Clinical Indications & Usage

Contraception: Indicated for the long-term prevention of pregnancy. A single injection provides highly reliable contraceptive coverage for 3 months (12–13 weeks).

Endometrial Protection: In certain clinical protocols, MPA is used to provide endometrial protection in postmenopausal women receiving estrogen replacement therapy.

Secondary Amenorrhea: Utilized in the management of secondary amenorrhea and abnormal uterine bleeding due to hormonal imbalance.

2. Mechanism of Action

Medroxy 150 functions through a robust endocrine feedback mechanism:

Ovulation Suppression: By maintaining sustained high levels of progestogen, it inhibits the release of gonadotropins (FSH and LH) from the pituitary gland, thereby preventing the maturation of ovarian follicles and the LH surge required for ovulation.

Cervical Barrier: It significantly increases the viscosity of cervical mucus, creating a mechanical and biological barrier that prevents sperm penetration.

Endometrial Inhibition: It induces a thin, atrophic endometrium, making it highly unfavorable for the implantation of a fertilized ovum.

3. Administration and Dosing

Route: Administered by deep intramuscular (IM) injection, typically into the gluteal, deltoid, or anterior thigh muscle.

Dosing: The standard contraceptive dose is 150mg.

Schedule: To maintain contraceptive efficacy, the injection must be administered every 12 to 13 weeks.

Professional Requirement: This medication must be administered by a qualified healthcare professional. The suspension should be shaken well before use to ensure a uniform mixture.

⚠️ Safety, Side Effects, and Monitoring

Contraindications: Do not use if there is a known or suspected pregnancy, undiagnosed vaginal bleeding, severe liver dysfunction, thrombophlebitis, history of thromboembolic disorders, or known breast cancer.

Important Considerations:

Bone Mineral Density (BMD): Prolonged use may result in a decrease in bone mineral density. Patients should be advised to ensure adequate calcium and Vitamin D intake.

Menstrual Changes: Irregular bleeding, spotting, or amenorrhea are common during the first few months of use.

Common Side Effects: Weight gain, headache, abdominal discomfort, nervousness, dizziness, and fatigue.

📦 Storage, Stability & Commercial Packaging

Storage: Store at controlled room temperature (20°C to 25°C / 68°F to 77°F).

Protection: Keep in original packaging to protect from light. Do not freeze.

Security: Keep securely out of reach of children.

PRESCRIPTION MEDICINE IS : YES.

Disclaimer: This profile is compiled strictly for international wholesale procurement and commercial educational research. Medroxy 150 is a prescription medicine and must be utilized solely under the direct guidance of a registered medical specialist. All cross-border importing setups must comply with the native health authorities of the destination country.

📞 Contact Ernest Impex — Pharmaceutical Exporter from India

[GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.]

🌐 Official Websites:

www.ernestimpex.com

www.oncologymedicinesupplier.com

www.ernestpharmaceuticals.com

www.ernestvision.com

📧 Corporate Email: exports@ernestpharmaceuticals.com

📦 Business Type: Exporter | Bulk Supplier | Distributor

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