contraceptives

Product Profile: Medroxy 150 (Medroxyprogesterone Acetate 150mg/ml) Medroxy 150 is a sterile, aqueous injectable suspension containing Medroxyprogesterone Acetate (MPA), a potent synthetic progestogen. It serves as a highly effective, long-acting depot contraceptive administered via intramuscular injection. 1. Clinical Indications & Usage Contraception: Indicated for the long-term prevention of pregnancy. A single injection provides highly reliable contraceptive coverage for 3 months (12–13 weeks). Endometrial Protection: In certain clinical protocols, MPA is used to provide endometrial protection in postmenopausal women receiving estrogen replacement therapy. Secondary Amenorrhea: Utilized in the management of secondary amenorrhea and abnormal uterine bleeding due to hormonal imbalance. 2. Mechanism of Action Medroxy 150 functions through a robust endocrine feedback mechanism: Ovulation Suppression: By maintaining sustained high levels of progestogen, it inhibits the release of gonadotropins (FSH and LH) from the pituitary gland, thereby preventing the maturation of ovarian follicles and the LH surge required for ovulation. Cervical Barrier: It significantly increases the viscosity of cervical mucus, creating a mechanical and biological barrier that prevents sperm penetration. Endometrial Inhibition: It induces a thin, atrophic endometrium, making it highly unfavorable for the implantation of a fertilized ovum. 3. Administration and Dosing Route: Administered by deep intramuscular (IM) injection, typically into the gluteal, deltoid, or anterior thigh muscle. Dosing: The standard contraceptive dose is 150mg. Schedule: To maintain contraceptive efficacy, the injection must be administered every 12 to 13 weeks. Professional Requirement: This medication must be administered by a qualified healthcare professional. The suspension should be shaken well before use to ensure a uniform mixture. ⚠️ Safety, Side Effects, and Monitoring Contraindications: Do not use if there is a known or suspected pregnancy, undiagnosed vaginal bleeding, severe liver dysfunction, thrombophlebitis, history of thromboembolic disorders, or known breast cancer. Important Considerations: Bone Mineral Density (BMD): Prolonged use may result in a decrease in bone mineral density. Patients should be advised to ensure adequate calcium and Vitamin D intake. Menstrual Changes: Irregular bleeding, spotting, or amenorrhea are common during the first few months of use. Common Side Effects: Weight gain, headache, abdominal discomfort, nervousness, dizziness, and fatigue. 📦 Storage, Stability & Commercial Packaging Storage: Store at controlled room temperature (20°C to 25°C / 68°F to 77°F). Protection: Keep in original packaging to protect from light. Do not freeze. Security: Keep securely out of reach of children. PRESCRIPTION MEDICINE IS : YES. Disclaimer: This profile is compiled strictly for international wholesale procurement and commercial educational research. Medroxy 150 is a prescription medicine and must be utilized solely under the direct guidance of a registered medical specialist. All cross-border importing setups must comply with the native health authorities of the destination country. 📞 Contact Ernest Impex — Pharmaceutical Exporter from India [GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.] 🌐 Official Websites: www.ernestimpex.com www.oncologymedicinesupplier.com www.ernestpharmaceuticals.com www.ernestvision.com 📧 Corporate Email: exports@ernestpharmaceuticals.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 93599 02383 📲 WhatsApp Link: https://wa.me/919359902383

Product Profile: Mifeshree 200 (Mifepristone 200mg) Mifeshree 200 contains Mifepristone, a synthetic steroid compound that acts as a potent progesterone receptor antagonist. It is primarily used in clinical settings as part of a medical regimen for the termination of intrauterine pregnancy or for the management of specific gynecological conditions. 1. Clinical Indications & Usage Medical Termination of Pregnancy: Indicated for use in conjunction with a prostaglandin analogue (such as misoprostol) for the medical termination of a developing intrauterine pregnancy up to a specific gestational limit, as defined by local medical protocols and regulatory guidelines. Cushing’s Syndrome: In specific clinical contexts, it may be used to control hyperglycemia secondary to hypercortisolism in adult patients with endogenous Cushing’s syndrome who are not candidates for surgery or have failed surgical intervention. 2. Mechanism of Action Mifepristone functions by binding to progesterone receptors with high affinity: Progesterone Blockade: By competitively blocking the action of progesterone—the hormone essential for maintaining the pregnancy—it induces decidual necrosis and detachment of the embryo from the uterine wall. Uterine Sensitization: It increases the sensitivity of the myometrium to prostaglandins, which facilitates uterine contractions. Cervical Softening: It promotes cervical ripening, aiding in the expulsion of the uterine contents. 3. Administration and Dosing Administration: Oral tablet. Regimen: Must be administered only under the direct supervision of a qualified medical practitioner in a clinical setting authorized for such procedures. Strict Protocol: The use of Mifepristone is strictly governed by medical protocols that mandate pre-treatment assessment (confirming gestational age and excluding ectopic pregnancy) and post-treatment follow-up to ensure complete evacuation. ⚠️ Safety, Contraindications, and Monitoring Contraindications: Should not be used in patients with a confirmed or suspected ectopic pregnancy, chronic adrenal failure, concurrent long-term corticosteroid therapy, history of allergy to mifepristone, or bleeding disorders. Critical Warnings: If the medical termination procedure fails, a surgical intervention is necessary to terminate the pregnancy. Patients must have access to emergency medical care for potential complications such as severe hemorrhage or infection. 📦 Storage, Stability & Commercial Packaging Storage: Store at room temperature (below 30°C / 86°F). Protection: Keep in the original blister packaging to protect from light and moisture. Security: Must be stored under restricted access due to its specialized clinical application. PRESCRIPTION MEDICINE IS : YES Disclaimer: This profile is compiled strictly for international wholesale procurement and commercial educational research. Mifeshree 200 is a highly specialized prescription medication and must be utilized strictly under the supervision of a licensed physician. All import and usage must adhere to the laws and medical regulations of the destination country 📞 Contact Ernest Impex — Pharmaceutical Exporter from India [GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.] 🌐 Official Websites: www.ernestimpex.com www.oncologymedicinesupplier.com www.ernestpharmaceuticals.com www.ernestvision.com 📧 Corporate Email: exports@ernestpharmaceuticals.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 93599 02383 📲 WhatsApp Link: https://wa.me/919359902383

Product Profile: Noret-EN 200 (Norethisterone Enanthate 200mg Injection) Noret-EN 200 contains Norethisterone Enanthate, a long-acting injectable progestogen contraceptive. It provides a reliable, depot-based method of hormonal birth control, offering protection for approximately two months per injection. 1. Clinical Indications & Usage Long-Acting Contraception: Indicated for the prevention of pregnancy. It is an ideal option for women who prefer a long-acting injectable method over daily oral contraceptive regimens. Cycle Management: Can be utilized in the short-term management of menstrual disorders, such as dysfunctional uterine bleeding or to delay menstruation for specific clinical or personal reasons. 2. Mechanism of Action Norethisterone Enanthate acts through several key hormonal pathways: Ovulation Inhibition: By maintaining a steady systemic level of progestogen, it suppresses the mid-cycle surge of luteinizing hormone (LH), thereby preventing the release of an egg from the ovary. Cervical Barrier: It increases the viscosity of cervical mucus, creating a formidable barrier that effectively inhibits sperm motility and migration into the uterus. Endometrial Thinning: The continuous progestogenic effect causes thinning of the endometrial lining, which renders the uterus unreceptive to embryo implantation. 3. Administration and Dosing Route: Administered by deep intramuscular (IM) injection, typically in the gluteal muscle. Dosing: The standard dose is 200mg. The duration of contraceptive effect is generally 8 weeks (2 months). Requirement: Must be administered by a trained healthcare professional. The injection site should be cleaned appropriately to ensure an aseptic procedure. ⚠️ Safety, Side Effects, and Monitoring Contraindications: Should not be used in patients with a history of venous thromboembolism (blood clots), undiagnosed vaginal bleeding, severe liver disease, hormone-sensitive malignancies (such as breast cancer), or during pregnancy. Common Side Effects: The most frequent side effect is an alteration of the menstrual pattern, which may include irregular bleeding, spotting, or temporary amenorrhea (absence of periods). Other side effects may include weight changes, headache, mood fluctuations, or breast tenderness. Return to Fertility: There may be a delay in the return of regular ovulation and fertility after the discontinuation of the injection. 📦 Storage, Stability & Commercial Packaging Storage: Store at room temperature (below 30°C / 86°F). Protection: Keep in original packaging to protect from light. Do not refrigerate or freeze. Security: Keep out of reach of children. PRESCRIPTION MEDICINE IS: YES. Disclaimer: This profile is compiled strictly for international wholesale procurement and commercial educational research. Noret-EN 200 is a prescription medicine and must be utilized solely under the direct guidance of a registered medical specialist. All cross-border importing setups must comply with the native health authorities of the destination country 📞 Contact Ernest Impex — Pharmaceutical Exporter from India [GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.] 🌐 Official Websites: www.ernestimpex.com www.oncologymedicinesupplier.com www.ernestpharmaceuticals.com www.ernestvision.com 📧 Corporate Email: exports@ernestpharmaceuticals.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 93599 02383 📲 WhatsApp Link: https://wa.me/919359902383

Product Profile: Noret-EL (Ethinylestradiol & Norethindrone Tablets) Noret-EL is a combined oral contraceptive (COC) containing Norethindrone (a first-generation progestogen) and Ethinylestradiol (a synthetic estrogen). This classic formulation is highly effective for pregnancy prevention and is frequently used to manage menstrual cycle symptoms. 1. Clinical Indications & Usage Oral Contraception: Indicated for the prevention of pregnancy. Menstrual Cycle Regulation: Often prescribed to manage irregular cycles, treat dysmenorrhea (painful menstruation), and reduce heavy menstrual blood loss. Hormonal Support: May be used to address symptoms of premenstrual syndrome (PMS) by stabilizing hormonal fluctuations. 2. Mechanism of Action Noret-EL works through a well-established triple-action mechanism: Ovulation Suppression: The combination of estrogen and progestogen acts on the hypothalamus and pituitary gland to suppress the release of FSH and LH, thereby preventing follicular development and ovulation. Cervical Mucus Thickening: Norethindrone increases the viscosity of cervical mucus, creating a formidable barrier that impedes sperm transport into the upper reproductive tract. Endometrial Inhibition: The hormonal regimen alters the uterine lining (endometrium), making the environment less favorable for implantation. 3. Administration and Dosing Regimen: Packaged in 21-day or 28-day cycles. Consistent daily administration at the same time is critical for maintaining effective hormone levels. Consistency: Adherence is paramount. Missing a dose significantly increases the risk of breakthrough ovulation. ⚠️ Safety, Side Effects, and Monitoring Contraindications: Should not be used in patients with a history of venous or arterial thromboembolism (blood clots), liver dysfunction, severe hypertension, estrogen-sensitive malignancies, or undiagnosed vaginal bleeding. Smoking Warning: Smoking cigarettes significantly increases the risk of serious cardiovascular events (stroke, myocardial infarction) in women using combined oral contraceptives, especially those aged 35 and older. Tobacco use is strongly discouraged. Common Side Effects: Nausea, breast tenderness, breakthrough bleeding (common in the first 3 months), weight fluctuations, headaches, and mood changes. 📦 Storage, Stability & Commercial Packaging Storage Environment: Store at room temperature (below 30°C / 86°F) in a cool, dry place. Protection: Keep in original blister packaging to prevent moisture, heat, and direct light degradation. Security: Keep securely out of reach of children and pets. PRESCRIPTION MEDICINE IS: YES. Disclaimer: This profile is compiled strictly for international wholesale procurement and commercial educational research. Noret-EL is a prescription medicine and must be utilized solely under the direct guidance of a registered medical specialist. All cross-border importing setups must comply with the native health authorities of the destination country 📞 Contact Ernest Impex — Pharmaceutical Exporter from India [GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.] 🌐 Official Websites: www.ernestimpex.com www.oncologymedicinesupplier.com www.ernestpharmaceuticals.com www.ernestvision.com 📧 Corporate Email: exports@ernestpharmaceuticals.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 93599 02383 📲 WhatsApp Link: https://wa.me/919359902383

Product Profile: Nevon-EL (Norgestrel & Ethinylestradiol Tablets) Nevon-EL is a combined oral contraceptive (COC) that utilizes Norgestrel (a potent progestogen) and Ethinylestradiol (a synthetic estrogen). This classic, well-established hormonal formulation provides high-efficacy protection against unintended pregnancy and is effective in managing menstrual cycle consistency. 1. Clinical Indications & Usage Oral Contraception: Indicated for the prevention of pregnancy in women of reproductive age. Cycle Management: Often used to regulate menstrual cycles, decrease the volume of menstrual flow, and manage symptoms associated with dysmenorrhea (painful menstruation). 2. Mechanism of Action The combination of Norgestrel and Ethinylestradiol achieves contraception through three primary hormonal actions: Suppression of Ovulation: By providing consistent levels of estrogen and progestogen, the medication inhibits the release of gonadotropins (LH and FSH), preventing the maturation and release of an ovum. Cervical Mucus Barrier: Norgestrel increases the viscosity and opacity of cervical mucus, creating a formidable physical and chemical barrier that inhibits sperm motility and penetration into the uterus. Endometrial Modification: The presence of these hormones alters the uterine lining (endometrium), rendering it less receptive to the implantation of a fertilized ovum. 3. Administration and Dosing Regimen: Packaged in a 21-day or 28-day cycle. Strict adherence to taking one tablet daily at the same time is required to maintain steady-state serum hormone levels. Consistency: Consistency is the foundation of efficacy. Missing a dose increases the risk of breakthrough ovulation or spotting. ⚠️ Safety, Side Effects, and Monitoring Contraindications: Do not use if the patient has a history of venous or arterial thromboembolism (blood clots), liver dysfunction, severe hypertension, estrogen-sensitive malignancies, or undiagnosed vaginal bleeding. Smoking Warning: Smoking increases the risk of serious cardiovascular complications (such as myocardial infarction or stroke) for women using combined hormonal contraceptives. This risk is compounded by age (especially over 35) and heavy tobacco use. Common Side Effects: Nausea, breast tenderness, breakthrough bleeding (particularly in early cycles), weight changes, headache, and mood fluctuations. 📦 Storage, Stability & Commercial Packaging Storage: Store at room temperature (below 30°C / 86°F) in a cool, dry location. Protection: Keep in original blister packaging to protect from moisture, heat, and UV light. Security: Keep strictly out of reach of children and domestic pets. PRESCRIPTION MEDICINE IS: YES. Disclaimer: This profile is compiled strictly for international wholesale procurement and commercial educational research. Nevon-EL is a prescription medicine and must be utilized solely under the direct guidance of a registered medical specialist. All cross-border importing setups must comply with the native health authorities of the destination country 📞 Contact Ernest Impex — Pharmaceutical Exporter from India [GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.] 🌐 Official Websites: www.ernestimpex.com www.oncologymedicinesupplier.com www.ernestpharmaceuticals.com www.ernestvision.com 📧 Corporate Email: exports@ernestpharmaceuticals.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 93599 02383 📲 WhatsApp Link: https://wa.me/919359902383

Product Profile: Drospi-EL (Drospirenone & Ethinylestradiol Tablets) Drospi-EL is an advanced combined oral contraceptive (COC) that integrates Drospirenone (a unique progestogen with anti-mineralocorticoid and anti-androgenic properties) and Ethinylestradiol (a synthetic estrogen). This formulation is widely recognized for its high contraceptive efficacy and its ability to mitigate common hormonal side effects associated with older progestogens. 1. Clinical Indications & Usage Oral Contraception: Indicated for the prevention of pregnancy in women who choose an oral contraceptive. Premenstrual Dysphoric Disorder (PMDD): Used for the treatment of emotional and physical symptoms of PMDD in women who choose an oral contraceptive as a method of birth control. Moderate Acne: Indicated for the treatment of moderate acne vulgaris in women who have reached menarche, are at least 14 years of age, and wish to use an oral contraceptive for birth control. 2. Mechanism of Action Drospi-EL utilizes a dual-action approach: Hormonal Suppression: The estrogen and progestogen components inhibit the secretion of gonadotropins (FSH and LH), thereby suppressing ovulation and altering cervical mucus to prevent sperm migration. Anti-mineralocorticoid Activity: Unlike other progestogens, Drospirenone mimics the effects of spironolactone. This helps counteract the estrogen-induced fluid retention, potentially reducing symptoms like bloating, breast tenderness, and weight gain. Anti-androgenic Profile: It helps reduce the stimulation of sebaceous glands by androgens, making it effective in improving skin clarity (acne management). 3. Administration and Dosing Regimen: Typically provided in a 21-day or 28-day cycle format. It is essential to take one tablet daily at the same time each day to maintain stable hormone levels. Consistency: Strict adherence to the dosing schedule is required to ensure both contraceptive protection and therapeutic effect. ⚠️ Safety, Side Effects, and Monitoring Contraindications: Do not use if the patient has a history of renal insufficiency, hepatic dysfunction, adrenal insufficiency, thromboembolic disorders, hormone-sensitive malignancies, or undiagnosed vaginal bleeding. Smoking Warning: Smoking increases the risk of serious cardiovascular events (myocardial infarction, stroke) in women using combined oral contraceptives, especially those over 35. Smoking should be avoided. Common Side Effects: Breakthrough bleeding, nausea, breast tenderness, mood changes, and headaches. Due to its anti-mineralocorticoid effect, potassium levels should be monitored in women taking other medications that might increase potassium (e.g., ACE inhibitors, NSAIDs). 📦 Storage, Stability & Commercial Packaging Storage Environment: Store in a cool, dry place at room temperature (below 30°C / 86°F). Protection: Maintain in original blister packaging to protect from moisture, heat, and UV light exposure. Security: Keep strictly out of reach of children. PRESCRIPTION MEDICINE IS: YES. Disclaimer: This profile is compiled strictly for international wholesale procurement and commercial educational research. Drospi-EL is a prescription medicine and must be utilized solely under the direct guidance of a registered medical specialist. All cross-border importing setups must comply with the native health authorities of the destination country 📞 Contact Ernest Impex — Pharmaceutical Exporter from India [GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.] 🌐 Official Websites: www.ernestimpex.com www.oncologymedicinesupplier.com www.ernestpharmaceuticals.com www.ernestvision.com 📧 Corporate Email: exports@ernestpharmaceuticals.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 93599 02383 📲 WhatsApp Link: https://wa.me/919359902383

Product Profile: Levon-FR (Levonorgestrel, Ethinylestradiol & Ferrous Fumarate) Levon-FR is a comprehensive oral contraceptive tablet that combines standard hormonal contraception with essential iron supplementation. It contains Levonorgestrel (progestogen), Ethinylestradiol (estrogen), and Ferrous Fumarate (iron), providing a dual-benefit approach for women who require both pregnancy prevention and support against iron deficiency. 1. Clinical Indications & Usage Oral Contraception: Indicated for the prevention of pregnancy. Iron Supplementation: The inclusion of Ferrous Fumarate is designed to prevent or treat iron-deficiency anemia, which can occur as a result of menstrual blood loss in some women. Cycle Regulation: Helps manage regular menstrual cycles and reduces the severity of dysmenorrhea. 2. Mechanism of Action Hormonal Pathway: Like other combined oral contraceptives (COCs), the Levonorgestrel and Ethinylestradiol components suppress the release of gonadotropins (FSH and LH), thereby inhibiting ovulation, thickening cervical mucus to prevent sperm entry, and altering the endometrium to prevent implantation. Hematological Pathway: Ferrous Fumarate provides elemental iron, which is essential for the synthesis of hemoglobin. This helps maintain adequate iron stores and prevents anemia-related symptoms such as fatigue and weakness during the menstrual cycle. 3. Administration and Dosing Regimen: Typically provided in a 28-day cycle pack. This includes active hormonal tablets and non-hormonal placebo/iron-only tablets. Consistency: Strict daily administration at the same time is required. The iron-containing tablets are usually taken during the week of the withdrawal bleed to ensure continuous daily habit and iron intake. ⚠️ Safety, Side Effects, and Monitoring Contraindications: Should not be used by women with a history of venous or arterial thromboembolism (blood clots), liver tumors, severe hypertension, estrogen-dependent malignancies, or undiagnosed vaginal bleeding. Smoking Warning: Smoking cigarettes increases the risk of serious cardiovascular events (stroke, myocardial infarction), especially in women over 35. Common Side Effects: Nausea, breast tenderness, breakthrough bleeding, weight changes, headache, and mood swings. Iron supplementation may cause gastrointestinal symptoms such as constipation or dark-colored stools. 📦 Storage, Stability & Commercial Packaging Storage: Store in a cool, dry environment (below 30°C / 86°F). Protection: Keep in the original blister packaging to ensure protection from moisture, light, and heat. Security: Keep securely out of reach of children, as iron-containing products can be toxic if ingested in large quantities. PRESCRIPTION MEDICINE IS : YES.📞 Contact Ernest Impex — Pharmaceutical Exporter from India [GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.] 🌐 Official Websites: www.ernestimpex.com www.oncologymedicinesupplier.com www.ernestpharmaceuticals.com www.ernestvision.com 📧 Corporate Email: exports@ernestpharmaceuticals.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 93599 02383 📲 WhatsApp Link: https://wa.me/919359902383 Disclaimer: This profile is compiled strictly for international wholesale procurement and commercial educational research. Levon-FR is a prescription medicine and must be utilized solely under the direct guidance of a registered medical specialist. All cross-border importing setups must comply with the native health authorities of the destination country

Product Profile: Levon EL-0.15 (Levonorgestrel & Ethinylestradiol) Levon EL-0.15 is a reliable combined oral contraceptive (COC) containing two active hormonal agents: Levonorgestrel (a potent progestogen) and Ethinylestradiol (a synthetic estrogen). This combination is widely utilized for the prevention of unintended pregnancy and the effective management of menstrual cycle irregularities. 1. Clinical Indications & Usage Oral Contraception: Indicated for the prevention of pregnancy in women of childbearing age. Cycle Regulation: Often prescribed to manage irregular menstrual patterns, reduce the intensity of dysmenorrhea (period pain), and address symptoms of cycle-related hormonal imbalances. 2. Mechanism of Action Levon EL-0.15 operates through a synchronized hormonal feedback mechanism: Ovulation Suppression: The estrogen and progestogen components inhibit the secretion of gonadotropins (FSH and LH) from the pituitary gland, effectively preventing the maturation and release of an ovum. Cervical Mucus Barrier: Levonorgestrel increases the viscosity of cervical secretions, creating a significant physical barrier that inhibits sperm migration into the uterus. Endometrial Modification: The hormonal combination renders the uterine lining (endometrium) less receptive to embryo implantation. 3. Administration and Dosing Regimen: Typically provided in a 21-day or 28-day cycle format. Consistent, daily administration at the same time each day is essential to maintain steady plasma hormone concentrations. Consistency: Strict adherence to the dosing schedule is required to ensure maximum contraceptive reliability. ⚠️ Safety, Side Effects, and Monitoring Contraindications: Should not be used in patients with a history of venous thromboembolism (blood clots), arterial thrombosis, liver dysfunction, severe hypertension, estrogen-sensitive malignancies, or undiagnosed vaginal bleeding. Smoking Warning: Smoking increases the risk of serious cardiovascular adverse effects (such as stroke or myocardial infarction) in women taking combined oral contraceptives. This risk increases significantly with age and heavy tobacco use. Common Side Effects: Nausea, breast tenderness, breakthrough bleeding (particularly during the first cycle), weight changes, headache, and mood alterations. 📦 Storage, Stability & Commercial Packaging Storage Environment: Store in a cool, dry area at room temperature (below 30°C / 86°F). Protection: Maintain in original blister packaging to protect from moisture, heat, and UV light. Security: Keep securely out of reach of children and pets. PRESCRIPTION MEDICINE IS: YES. Disclaimer: This profile is compiled strictly for international wholesale procurement and commercial educational research. Levon EL-0.15 is a prescription medicine and must be utilized solely under the direct guidance of a registered medical specialist. All cross-border importing setups must comply with the native health authorities of the destination country. 📞 Contact Ernest Impex — Pharmaceutical Exporter from India [GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.] 🌐 Official Websites: www.ernestimpex.com www.oncologymedicinesupplier.com www.ernestpharmaceuticals.com www.ernestvision.com 📧 Corporate Email: exports@ernestpharmaceuticals.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 93599 02383 📲 WhatsApp Link: https://wa.me/919359902383

Product Profile: Levon EL-0.10 (Levonorgestrel & Ethinylestradiol) Levon EL-0.10 is a combined oral contraceptive (COC) tablet containing two potent synthetic hormones: Levonorgestrel (a second-generation progestogen) and Ethinylestradiol (an estrogen). This combination is highly reliable for preventing pregnancy and managing hormonal cycles. 1. Clinical Indications & Usage Oral Contraception: Indicated for the prevention of pregnancy in women of childbearing age. Cycle Regulation: Frequently prescribed to help manage irregular menstrual cycles, reduce the severity of dysmenorrhea (period pain), and lower the risk of iron-deficiency anemia by reducing menstrual blood loss. 2. Mechanism of Action The combination of Levonorgestrel and Ethinylestradiol works via a sophisticated hormonal feedback loop: Suppression of Ovulation: The estrogenic and progestogenic components inhibit the release of gonadotropin-releasing hormone (GnRH), which prevents the surge of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) required for ovulation. Cervical Mucus Modification: Levonorgestrel increases the viscosity and acidity of cervical mucus, making it difficult for sperm to penetrate the cervix and reach the fallopian tubes. Endometrial Inhibition: The combined therapy alters the uterine lining (endometrium), making it less receptive to the implantation of a fertilized egg. 3. Administration and Dosing Regimen: Typically packaged in a 21-day or 28-day cycle format. It is imperative that the patient takes one tablet daily at the same time each day to ensure constant hormone concentrations. Consistency: Adherence to the daily schedule is essential for both contraceptive efficacy and the stabilization of the hormonal profile. ⚠️ Safety, Side Effects, and Monitoring Contraindications: Do not use if there is a history of venous or arterial thromboembolism (blood clots), liver dysfunction, severe hypertension, estrogen-dependent tumors, or undiagnosed vaginal bleeding. Smoking Warning: The use of combined oral contraceptives significantly increases the risk of serious cardiovascular events (e.g., myocardial infarction, stroke) in women who smoke, particularly those older than 35. Smoking should be avoided during treatment. Common Side Effects: Nausea, breast tenderness, weight fluctuations, breakthrough bleeding, mood changes, and headaches. 📦 Storage, Stability & Commercial Packaging Storage: Store at room temperature (below 30°C / 86°F). Protection: Keep in original blister packaging to protect against moisture, heat, and direct UV light exposure. Security: Keep strictly out of reach of children and domestic pets. PRESCRIPTION MEDICINE IS : YES. Disclaimer: This profile is compiled strictly for international wholesale procurement and commercial educational research. Levon EL-0.10 is a prescription medicine and must be utilized solely under the direct guidance of a registered medical specialist. All cross-border importing setups must comply with the native health authorities of the destination country. 📞 Contact Ernest Impex — Pharmaceutical Exporter from India [GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.] 🌐 Official Websites: www.ernestimpex.com www.oncologymedicinesupplier.com www.ernestpharmaceuticals.com www.ernestvision.com 📧 Corporate Email: exports@ernestpharmaceuticals.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 93599 02383 📲 WhatsApp Link: https://wa.me/919359902383

Product Profile: Deova (Desogestrel & Ethinylestradiol Tablets) Deova is a combined oral contraceptive (COC) containing two active hormonal agents: Desogestrel (a third-generation progestogen) and Ethinylestradiol (a synthetic estrogen). This combination is widely prescribed for reliable contraception and the management of hormonal cycles. 1. Clinical Indications & Usage Oral Contraception: Indicated for the prevention of pregnancy in women. Cycle Regulation: Often prescribed to manage menstrual irregularities, reduce dysmenorrhea (painful periods), and control cycle length. Hormonal Balance: Desogestrel is known for its lower androgenic activity compared to older progestogens, often making it a preferred choice for patients concerned about androgen-related side effects like acne. 2. Mechanism of Action Deova employs a multi-faceted hormonal approach to prevent pregnancy: Ovulation Inhibition: The estrogen and progestogen components work synergistically to suppress the hypothalamic-pituitary-gonadal axis, preventing the mid-cycle LH surge necessary for ovulation. Cervical Mucus Thickening: The progestogen increases the viscosity of cervical mucus, creating a formidable barrier that prevents sperm penetration into the uterus. Endometrial Alteration: The combined hormones render the endometrium less receptive to embryo implantation. 3. Administration and Dosing Regimen: Typically provided in a 21-day or 28-day pack. Tablets must be taken daily at the same time each day to maintain consistent hormone levels. Consistency: Adherence is vital for maximum contraceptive efficacy. If a dose is missed, patients should follow specific protocols provided in the patient information leaflet or by their prescribing physician. ⚠️ Safety, Side Effects, and Monitoring Contraindications: Do not use if the patient has a history of venous or arterial thromboembolism (blood clots), liver tumors or disease, undiagnosed vaginal bleeding, or hormone-sensitive malignancies. Smoking Warning: Cigarette smoking significantly increases the risk of serious cardiovascular side effects (such as myocardial infarction or stroke) when using combined hormonal contraceptives. This risk is notably higher in women over 35 who smoke. Common Side Effects: Nausea, breast tenderness, weight gain, breakthrough bleeding (especially in the first few months), headache, or mood fluctuations. PRESCRIPTION MEDICINE IS: YES. 📦 Storage, Stability & Commercial Packaging Storage Environment: Store in a dry place at room temperature (below 30°C / 86°F). Protection: Keep in the original blister packaging to protect from moisture, heat, and direct light. Security: Keep out of reach of children and domestic pets. PRESCRIPTION MEDICINE IS : YES Disclaimer: This profile is compiled strictly for international wholesale procurement and commercial educational research. Deova is a prescription medicine and must be utilized solely under the direct guidance of a registered medical specialist. All cross-border importing setups must comply with the native health authorities of the destination country. 📞 Contact Ernest Impex — Pharmaceutical Exporter from India [GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.] 🌐 Official Websites: www.ernestimpex.com www.oncologymedicinesupplier.com www.ernestpharmaceuticals.com www.ernestvision.com 📧 Corporate Email: exports@ernestpharmaceuticals.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 93599 02383 📲 WhatsApp Link: https://wa.me/919359902383

Product Profile: Evening Pill 1.5mg (Levonorgestrel) Evening Pill 1.5mg contains Levonorgestrel, a potent progestogen specifically formulated for emergency contraception. This high-dose, single-tablet regimen is designed to prevent unintended pregnancy following unprotected sexual intercourse or suspected contraceptive failure. 1. Clinical Indications & Usage Emergency Contraception: Indicated for the prevention of pregnancy when taken as soon as possible, ideally within 72 hours (3 days) of unprotected intercourse. Efficacy: As an emergency measure, its effectiveness is time-dependent; the sooner it is administered post-coitally, the higher the success rate in preventing ovulation. It is not intended to be used as a routine contraceptive method. 2. Mechanism of Action Levonorgestrel acts primarily through the following physiological pathways: Inhibition of Ovulation: By providing a surge of progestogen, it disrupts the hormonal signals (LH surge) required for the release of an egg from the ovary. Cervical Barrier: Increases the viscosity of cervical mucus, creating a mechanical and chemical barrier that inhibits sperm motility and migration. Endometrial Modification: It may induce changes in the uterine lining that are unfavorable for the implantation of a fertilized ovum. Note: Levonorgestrel has no effect on an established pregnancy and is not an abortifacient. 3. Administration and Dosing Dosing: The 1.5mg dose is a single-tablet regimen. Timing: Administer orally as soon as possible after unprotected sexual intercourse. Management: If vomiting occurs within 2 hours of taking the tablet, a replacement dose should be taken immediately to ensure contraceptive efficacy. ⚠️ Safety, Side Effects, and Monitoring Common Side Effects: Temporary menstrual cycle disturbances (early/late onset or changes in flow), nausea, fatigue, headache, dizziness, lower abdominal pain, and breast tenderness. Important Safety Notes: Does not protect against sexually transmitted infections (STIs) or HIV. If menstruation is delayed by more than 7 days beyond the expected date, a pregnancy test is required to rule out failure of the emergency contraceptive. PRESCRIPTION MEDICINE IS: YES. 📦 Storage, Stability & Commercial Packaging Environment: Store in a dry environment at controlled room temperature (15°C to 30°C / 59°F to 86°F). Protection: Maintain in original manufacturer’s blister packaging until the point of administration to protect against light and moisture. Security: Keep securely out of reach of children PRESCRIPTION MEDICINE IS : YES This profile is compiled strictly for international wholesale procurement and commercial educational research. Evening Pill 1.5mg is a specialized pharmaceutical product and must be utilized under the direct guidance of a medical professional. All cross-border importing setups must comply with the native health authorities of the destination country 📞 Contact Ernest Impex — Pharmaceutical Exporter from India [GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.] 🌐 Official Websites: www.ernestimpex.com www.oncologymedicinesupplier.com www.ernestpharmaceuticals.com www.ernestvision.com 📧 Corporate Email: exports@ernestpharmaceuticals.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 93599 02383 📲 WhatsApp Link: https://wa.me/919359902383

Product Profile: Evening Pill 0.75mg (Levonorgestrel) Evening Pill 0.75mg contains Levonorgestrel, a synthetic progestogen used primarily as emergency contraception. It is a highly effective, time-sensitive medical intervention intended to prevent unintended pregnancy after unprotected intercourse or contraceptive failure. 1. Clinical Indications & Usage Emergency Contraception: Indicated for use within 72 hours (3 days) of unprotected sexual intercourse to prevent pregnancy. Efficacy Note: The efficacy of Levonorgestrel is highest the sooner it is taken after unprotected intercourse. It is not intended for use as a regular or routine method of contraception. 2. Mechanism of Action Levonorgestrel prevents pregnancy through several biological mechanisms: Ovulation Inhibition/Delay: It works primarily by delaying or inhibiting ovulation if the follicular phase has not yet passed. Cervical Mucus Alteration: It thickens the cervical mucus, which impedes the transport of sperm into the upper reproductive tract. Endometrial Modification: It may alter the lining of the uterus (endometrium), potentially inhibiting the implantation of a fertilized egg. Note: Levonorgestrel is not effective if implantation has already occurred and is not an abortifacient. 3. Administration and Dosing Dosing: The standard emergency regimen involves the administration of 1.5mg total. This may be taken as two 0.75mg tablets taken simultaneously or one 0.75mg tablet followed by a second 0.75mg tablet 12 hours later, depending on specific clinical protocols. Timing: Must be taken as soon as possible after unprotected sex, ideally within 24 hours, but no later than 72 hours. Post-Administration: If vomiting occurs within 2 hours of ingestion, a replacement dose should be administered. ⚠️ Safety, Side Effects, and Monitoring Common Side Effects: Changes in the timing or flow of the next menstrual period (may be early or late), nausea, abdominal pain, fatigue, headache, dizziness, and breast tenderness. Important Considerations: Does not protect against HIV (AIDS) or other sexually transmitted infections (STIs). If the menstrual period is more than 5-7 days late after taking this medication, a pregnancy test should be performed to rule out failure of the emergency contraceptive. PRESCRIPTION MEDICINE IS: YES. (Though available over-the-counter in some jurisdictions, it remains a professional pharmaceutical product requiring proper clinical guidance). 📦 Storage, Stability & Commercial Packaging Storage Environment: Store in a dry place at controlled room temperature (15°C to 30°C / 59°F to 86°F). Protection: Keep in original packaging until use to protect from light and moisture. Security: Keep out of reach of children. PRESCRIPTION MEDICINE IS : YES Disclaimer: This profile is compiled strictly for international wholesale procurement and commercial educational research. Evening Pill 0.75mg is a specialized pharmaceutical product and must be utilized under the guidance of a medical professional. All cross-border importing setups must comply with the native health authorities of the destination country. 📞 Contact Ernest Impex — Pharmaceutical Exporter from India [GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.] 🌐 Official Websites: www.ernestimpex.com www.oncologymedicinesupplier.com www.ernestpharmaceuticals.com www.ernestvision.com 📧 Corporate Email: exports@ernestpharmaceuticals.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 93599 02383 📲 WhatsApp Link: https://wa.me/919359902383