Product Profile: Conshe 35 (Cyproterone Acetate & Ethinylestradiol) Conshe 35 is a combination oral contraceptive and anti-androgenic medication. It contains two active ingredients: Cyproterone Acetate (a synthetic progestogen with strong anti-androgenic properties) and Ethinylestradiol (a synthetic estrogen). This combination is highly effective in regulating hormonal balance and treating specific androgen-dependent conditions in women. 1. Clinical Indications & Usage Conshe 35 is indicated for the treatment of androgen-dependent conditions in women: Severe Acne: Specifically, acne that is unresponsive to prolonged antibiotic treatment or other dermatological therapies. Hirsutism: Treatment of moderate to severe hirsutism (excessive body hair growth). Androgenetic Alopecia: Management of androgen-related hair loss. Contraception: As it functions as a hormonal contraceptive, it is often prescribed to women who require treatment for the above conditions and also desire effective birth control. 2. Mechanism of Action Conshe 35 utilizes a dual-action approach: Anti-Androgenic Effect: Cyproterone acetate blocks the androgen receptors, preventing androgens (like testosterone) from exerting their effects on the skin (sebaceous glands) and hair follicles. Estrogenic Effect: Ethinylestradiol increases the production of sex hormone-binding globulin (SHBG) in the liver, which binds to free testosterone in the blood, further reducing its availability. Ovulation Inhibition: The hormonal combination suppresses the release of gonadotropins (FSH and LH), thereby inhibiting ovulation and altering cervical mucus to prevent conception. 3. Administration and Dosing Schedule: The tablets should be taken daily at approximately the same time for 21 consecutive days, followed by a 7-day tablet-free interval during which a withdrawal bleed typically occurs. Consistency: Adherence to the daily schedule is critical for both the efficacy of the dermatological treatment and for reliable contraceptive protection. ⚠️ Safety, Side Effects, and Monitoring Contraindications: Do not use if there is a history of venous thromboembolism (blood clots), arterial thrombosis, severe liver disease, hormone-dependent tumors (e.g., breast cancer), or undiagnosed vaginal bleeding. Smoking Warning: Smoking cigarettes while using combined oral contraceptives significantly increases the risk of serious cardiovascular side effects (e.g., heart attack, stroke). This risk increases with age and heavy smoking. Common Side Effects: Nausea, breast tenderness, weight fluctuations, mood changes, headache, and breakthrough bleeding. PRESCRIPTION MEDICINE IS: YES. 📦 Storage, Stability & Commercial Packaging Storage: Store at room temperature (below 30°C / 86°F). Protection: Keep in original blister packaging to protect from moisture, heat, and direct light. Security: Keep out of reach of children and domestic pets. PRESCRIPTION MEDICINE IS : YES. Clinical Disclaimer: This profile is compiled strictly for international wholesale procurement and commercial educational research. Conshe 35 is a prescription medicine and must be utilized solely under the direct guidance of a registered medical specialist. All cross-border importing setups must comply with the native health authorities of the destination country. 📞 Contact Ernest Impex — Pharmaceutical Exporter from India [GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.] 🌐 Official Websites: www.ernestimpex.com www.oncologymedicinesupplier.com www.ernestpharmaceuticals.com www.ernestvision.com 📧 Corporate Email: exports@ernestpharmaceuticals.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 93599 02383 📲 WhatsApp Link: https://wa.me/919359902383