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Female Hormones

Tamofar (Tamoxifen 20mg) Tablets: Verified Pharmaceutical Exporter from India | Bulk Supplier for USA, UK, Australia, Thailand, Singapore & Jamaica

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Description

Product Profile: Tamofar 20mg (Tamoxifen Citrate Tablets)

Tamofar 20mg contains Tamoxifen, a Selective Estrogen Receptor Modulator (SERM). It is a foundational medication in the treatment and prevention of hormone receptor-positive breast cancer, acting as a competitive antagonist of estrogen receptors in breast tissue.

1. Clinical Indications & Usage

Breast Cancer Treatment: Indicated for the adjuvant treatment of hormone receptor-positive breast cancer in women (both pre- and postmenopausal) to reduce the risk of recurrence. It is also used in the treatment of metastatic breast cancer.

Breast Cancer Prevention: Prescribed to reduce the risk of invasive breast cancer in women at high risk.

Ductal Carcinoma in Situ (DCIS): Used to reduce the risk of invasive breast cancer following surgery and radiation for DCIS.

2. Mechanism of Action

Tamoxifen functions through a tissue-specific modulation of estrogen receptors:

Antiestrogenic Effect (Breast): By binding to estrogen receptors in the breast, it prevents estrogen from stimulating the growth of cancer cells, thereby effectively inhibiting tumor proliferation in ER-positive cases.

Estrogenic Effect (Other Tissues): In other tissues, such as the endometrium and bone, Tamoxifen can exhibit estrogen-like (agonist) effects, which necessitates clinical monitoring for specific long-term health markers.

3. Administration and Dosing

Regimen: The standard adult dose is typically 20mg per day.

Duration: Treatment is often long-term, frequently spanning 5 to 10 years, as directed by an oncologist.

Administration: Tablets should be taken orally with water, generally at the same time each day, with or without food.

⚠️ Safety, Side Effects, and Monitoring

Contraindications: Do not use if there is a history of deep vein thrombosis (DVT) or pulmonary embolism (PE), if the patient is currently on anticoagulant therapy, or if the patient is pregnant.

Critical Warnings:

Endometrial Risks: Because of its potential agonist effects on the uterus, long-term use can increase the risk of endometrial cancer. Patients should report any abnormal vaginal bleeding immediately.

Thromboembolic Risk: There is an increased risk of stroke, DVT, and PE, particularly in patients with existing risk factors.

Common Side Effects: Hot flashes, vaginal discharge or bleeding, mood swings, nausea, fatigue, and leg cramps.

📦 Storage, Stability & Commercial Packaging

Storage: Store at controlled room temperature (20°C to 25°C / 68°F to 77°F).

Protection: Keep in original blister packaging to protect from light and moisture.

Security: Keep securely out of reach of children and others to prevent accidental ingestion.

PRESCRIPTION MEDICINE IS: YES.

Disclaimer: This profile is compiled strictly for international wholesale procurement and commercial educational research. Tamofar is a specialized prescription medication and must be utilized strictly under the supervision of a licensed oncologist or physician. All import and usage must adhere to the laws and medical regulations of the destination country.

📞 Contact Ernest Impex — Pharmaceutical Exporter from India

[GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.]

🌐 Official Websites:

www.ernestimpex.com

www.oncologymedicinesupplier.com

www.ernestpharmaceuticals.com

www.ernestvision.com

📧 Corporate Email: exports@ernestpharmaceuticals.com

📦 Business Type: Exporter | Bulk Supplier | Distributor

📲 WhatsApp: +91 93599 02383

📲 WhatsApp Link: https://wa.me/919359902383

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