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HIV/AIDS

Salt: Abacavir (300mg) Description Abec 300mg tablet contains the active ingredient Abacavir. It is an anti-retroviral drug that belongs to the family known as nucleoside analog reverse transcriptase inhibitors (NRTIs). It is used to treat HIV (human immunodeficiency virus). HIV-1 is a virus known as the Human immunodeficiency virus, which targets and eradicates immune system cells, ultimately weakening the body's defense against infections. If left untreated, it can result in death. While this medication does not offer a complete cure, it effectively lowers the virus levels in your body and boosts the count of CD4 cells in your bloodstream. These cells play a crucial role in assisting your body's fight against infections. Benefits In Treatment of HIV infection A-Bec Tablet decreases the amount of HIV in the body. It helps control the infection and makes the immune system work better. This ensures a long and healthy life. This drug is usually given in combination with other medicines. Avoid skipping doses and follow the doctor’s instructions carefully to get maximum benefits. In Treatment of Chronic hepatitis B virus (HBV) infection Chronic hepatitis B virus infection is a serious liver infection that has been there for at least 6 months and is still not cured. A-Bec Tablet helps treat this infection effectively. It lowers the chances of complications, such as new infections, and improves one’s quality of life. If this infection is not treated, it can lead to severe liver damage, which can cause other life-threatening problems, such as liver failure, or may also be fatal. Side Effects Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of A-Bec Headache Vomiting Fever Lethargy Decreased appetite Dizziness Muscle pain Hypersensitivity Altered liver function test Abdominal pain Abnormal dreams Rash Nausea Sleep disorder Ear, nose, and throat (ENT) infections Fatigue Diarrhea

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Anti-cancer medicines

Combinib 250mg Tablet is used in the treatment of breast cancer. It works by stopping or slowing down the growth of cancer cells. It is either used alone or in combination with some other medicine to cure advanced-stage breast cancer. Combinib 250mg Tablet should be taken on an empty stomach or an hour before or 2 hours after a meal. The dose and duration vary according to the severity of your condition and your response to treatment. Take it exactly as prescribed to avoid serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include nausea, headache, back pain, and breathing difficulty. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. You may be asked for regular monitoring of blood pressure while taking this medicine. Inform your doctor if you notice a severe headache, confusion, problems with your eyesight, nausea, or vomiting. Your doctor may check your liver function before, during, and after treatment with this medicine. Before taking Combinib 250mg Tablet, let your doctor know if you have liver or kidney problems. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are taking. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details. Uses of Combinib Tablet Pancreatic cancer Small cell lung cancer Liver cancer Kidney cancer Thyroid cancer Blood cancer (Chronic myeloid leukaemia) Gastrointestinal stromal tumour Cancer of colon and rectum Non-small cell lung cancer Soft tissue sarcoma Chronic idiopathic myelofibrosis Breast cancer Side effects of Combinib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Combinib Abdominal pain Back pain Breathing problems Constipation Cough Diarrhea Fatigue Headache Hot flashes Increased bilirubin in the blood Insomnia (difficulty in sleeping) Joint pain Liver damage Loss of appetite Mucosal inflammation Nausea Pain in extremities Rash Stomatitis (Inflammation of the mouth) Vomiting Weakness Weight gain How to use Combinib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combinib 250mg Tablet is to be taken empty stomach. How Combinib Tablet works Combinib 250mg Tablet is an anti-cancer medication. It works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which are responsible for the over-proliferation of cells. This is how it inhibits the growth of cancerous cells causing downstream signaling pathways. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Combinib 250mg Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Combinib 250mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Combinib 250mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Combinib 250mg Tablet may cause side effects which could affect your ability to drive. warnings Kidney CAUTION Combinib 250mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Combinib 250mg Tablet may be needed. Please consult your doctor. Limited information is available on the use of Combinib 250mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease. warnings Liver CAUTION Combinib 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Combinib 250mg Tablet may be needed. Please consult your doctor. Limited information is available on the use of this medicine in patients with the severe liver disease.

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Anti Cancer Medicine

INTRODUCTION ABOUT I DOX 20MG INJECTION I DOX 20MG INJECTION contains Doxorubicin which belongs to the group of medicines called Anti-cancer agents. It is used to manage certain types of cancers. It is used either alone or along with other anti-cancer medicines. Cancer is a disease in which some of the cells of the body grow uncontrollably and spread to other parts of the body. Before receiving I DOX 20MG INJECTION, inform your doctor if you have or ever had heart disease, either before or during radiotherapy, had or having live or live-attenuated vaccinations, are currently taking or have recently taken Trastuzumab (used in the management of certain cancers). There are no adequate and well-controlled studies in pregnant women. Consult your doctor during breast-feeding before starting management with this medicine as it may pass through the breast milk and possibly harm your child. Consult your doctor for advice before receiving the medicine. The most common side effects of I DOX 20MG INJECTION are infection, lack of appetite, inflammation in the mouth, diarrhea, nausea, vomiting, reddening, swelling, pain, numbness and tingling in the palms and feet may also occur whilst being managed with this medicine. Hair loss is very common and may be quite severe, beard growth may stop in men, fever, feeling weak, chills, abnormal ECG (electrical trace of the heart) results, raised levels of liver enzymes (as detected by a blood test) can determine if the medicine is having an abnormal effect on your liver, weight increased in patients with early breast cancer. USES OF I DOX 20MG INJECTION Used to manage certain types of cancer HOW I DOX 20MG INJECTION WORKS I DOX 20MG INJECTION works by suppressing the activity of an enzyme (topoisomerase II) involved in the DNA multiplication of the cancer cells. On the other hand, this also forms harmful chemicals (free radicals) which cause damage to the DNA. This slowdown the growth of cancer cells and eventually works against them. DIRECTIONS FOR USE I DOX 20MG INJECTION will be administered intravenously (IV) into the vein by your doctor or nurse. Your doctor will administer the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF I DOX 20MG INJECTION COMMON infection lack of appetite inflammation in the mouth diarrhea nausea, vomiting hair loss beard growth may stop (in men) redness, swelling and blistering on the palms of the hands and soles of the feet (palmar-plantar erythrodysesthesia syndrome) chills weakness abnormal ECG raised levels of liver enzymes weight increased in patients with early breast cancer blood poisoning heart problems conjunctivitis (red watery eyes) lacrimation, excess tear production shortness of breath and swelling of the ankles increased heart rate inflammation of the throat and gullet stomach pain skin rashes, redness, hives nails and skin may appear darker than usual injection site reactions such as redness and swelling neutropenia thrombocytopenia malaise/asthenia infertility (in women) absence or decrease in sperm count (in men) UNCOMMON embolism (blockage in the bloodstream) RARE Stop receiving I DOX 20MG INJECTION and contact your doctor immediately if you experience any of the following side effects: dizzy, feverish, short of breath with a tight chest or throat or having an itchy rash anemia (low red blood cell count) decrease in white blood cell counts which in turn causes an increase in infections and a raised temperature (fever) platelets can be affected which could make a bruise or bleed more easily decreased activity in bone marrow reddening of urine dehydration inflammation of veins irritation or bleeding in the intestines inflammation of the lining of the stomach heartburn soreness or ulcers in the mouth

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General Medicine

Colistican 3 Injection is an intravenous formulation containing Colistimethate Sodium 3 Million IU, manufactured by American Remedies. It is primarily used to treat severe infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 3 Injection Colistican 3 Injection is indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bloodstream Infections (Sepsis): Infections caused by resistant bacteria entering the bloodstream. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. • Intra-abdominal Infections: Such as peritonitis. • Cystic Fibrosis: For chronic pulmonary infections due to Pseudomonas aeruginosa in both adults and children. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

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Antibiotic Medicine

Colistican 2 Injection is a brand of Colistimethate Sodium for Injection, manufactured by American Remedies. It is a polymyxin-class antibiotic used to treat serious infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 2 Injection Colistican 2 Injection is primarily indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bacteremia (Bloodstream Infection): Infections caused by resistant bacteria entering the bloodstream. • Lower Respiratory Tract Infections: Including severe cases of pneumonia and bronchitis. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. These infections are typically caused by pathogens such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae, which are resistant to multiple antibiotics. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

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Antibiotic Medicine

Colistican 1 Injection is a brand of Colistimethate Sodium for Injection manufactured by American Remedies. Colistimethate sodium is a polymyxin-class antibiotic, also known as polymyxin E, used to treat serious infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 1 Injection Colistican 1 Injection is primarily used for: • Multidrug-Resistant Infections: Especially those caused by Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Urinary Tract Infections (UTIs): Caused by resistant Gram-negative bacteria. • Bloodstream Infections (Sepsis): Resulting from resistant pathogens. • Intra-abdominal Infections: Such as peritonitis. • Cystic Fibrosis: For chronic pulmonary infections due to Pseudomonas aeruginosa in both adults and children. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

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General Medicine

Artecan 60mg Injection is an antimalarial medication manufactured by American Remedies. It contains Artesunate 60 mg and is primarily used for the treatment of severe malaria, particularly cases caused by Plasmodium falciparum, the most dangerous malaria parasite. ________________________________________ 🩺 Uses of Artecan 60mg Injection Artecan 60mg Injection is indicated for: • Severe Malaria: Especially when oral antimalarial drugs are not feasible. • Cerebral Malaria: A life-threatening form of malaria affecting the brain. • Malaria with Complications: Such as organ failure or severe anemia. This injection is administered intravenously or intramuscularly by healthcare professionals in hospital settings. ________________________________________ 💊 How It Works Artesunate is a water-soluble derivative of artemisinin that acts by: • Inhibiting the growth of the malaria parasite. • Generating reactive oxygen species that damage the parasite's cell membranes. Effectively reducing parasitic load in the bloodstream. ________________________________________ ⚠️ Side Effects Common side effects may include: • Headache • Dizziness • Weakness • Loss of appetite • Injection site reactions (pain, swelling, redness) These side effects are generally mild and transient. However, if they persist or worsen, consult your healthcare provider. ________________________________________ ⚠️ Precautions Before using Artecan 60mg Injection, inform your doctor if you: • Have a history of allergies to Artesunate or artemisinin derivatives. Have liver or kidney disease. • Are pregnant, planning to become pregnant, or breastfeeding. • Are taking any other medications, including over-the-counter drugs and supplements. .

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Steroid/Hormones Medicines

TestoMix 250 mg is an injectable formulation containing a combination of four different testosterone esters: Testosterone Propionate (fast-acting) Testosterone Phenylpropionate Testosterone Isocaproate Testosterone Decanoate (long-acting) This blend is designed to provide both immediate and sustained release of testosterone into the bloodstream. ✅ Primary Uses Treatment of Male Hypogonadism TestoMix 250 mg is used to treat male hypogonadism, a condition where the body does not produce enough testosterone. This therapy helps in restoring normal testosterone levels, thereby improving symptoms such as low libido, fatigue, and muscle weakness. Hormone Replacement Therapy (HRT) It is used in hormone replacement therapy for transgender men as part of gender-affirming treatment. Anabolic Effects in Bodybuilding In the realm of bodybuilding, TestoMix 250 mg is utilized to enhance muscle mass, strength, and performance. Its rapid action makes it suitable for short-term bulking cycles.

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Erectile Dysfunction Medicine

Tadarise 10 mg is a medication primarily used to treat erectile dysfunction (ED) in men. It contains Tadalafil as its active ingredient, which belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. Main Uses of Tadarise 10 mg: Erectile Dysfunction (ED): Helps men achieve and maintain an erection sufficient for sexual activity. Works by increasing blood flow to the penis during sexual stimulation. Benign Prostatic Hyperplasia (BPH): (Off-label or under doctor’s prescription) Relieves symptoms like difficulty in urination, weak stream, and frequent urination. Relaxes muscles in the bladder and prostate. Pulmonary Arterial Hypertension (PAH): (Higher doses like 20 mg or as per doctor's advice) Helps relax blood vessels in the lungs to allow blood to flow more easily. How to Take: Usually taken 30–60 minutes before sexual activity. Do not take more than once a day. It can be taken with or without food. Important Notes: Requires sexual stimulation to be effective. Avoid alcohol and grapefruit juice as they can interfere with the drug’s effectiveness. Consult a doctor if you have heart conditions, liver/kidney issues, or are taking nitrates.

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