INTRODUCTION ABOUT TAXONAB 100MG INJECTION TAXONAB 100MG INJECTION contains Paclitaxel which belongs to a group of anti-cancer medicines called Taxanes. TAXONAB 100MG INJECTION is used to manage ovarian and breast cancer as a first line of therapy and as a second line of management when platinum containing medicines (such as cisplatin) or anthracyclines are insufficient to manage the disease in affected individuals. TAXONAB 100MG INJECTION is also used to manage advanced NSCLC (non-small cell lung cancer) when surgery/radiation therapy is not suitable. The medicine is also indicated for use to manage AIDS-related Kaposi’s sarcoma when other managements (such as anthracyclines) are insufficient to manage the disease in affected individuals. TAXONAB 100MG INJECTION is not recommended for use in patients allergic to paclitaxel and polyoxyethylated castor oil. It is also not recommended for use in patients with few white blood cells count and serious & uncontrolled infection. The medicine is also not used in patients suffering from severe liver disease. Before receiving TAXONAB 100MG INJECTION, inform your doctor if you had previously received radiation to your chest and/or suffering from thrombocytopenia (low platelet count)/acute infections (such as herpes zoster, chickenpox, herpes), kidney problems (such as chronic kidney disease), liver problems (such as mild/moderate hepatic impairment) and/or heart problems (such as severe coronary artery disease, myocardial infarction and arrhythmias). TAXONAB 100MG INJECTION is not recommended for use during pregnancy. Women of child-bearing potential should use effective contraception method while receiving TAXONAB 100MG INJECTION which should be continued for next-6 months after completing the management. The medicine is also not recommended for use in breastfeeding women. TAXONAB 100MG INJECTION is also not recommended for use in children and adolescents (aged below 18 years). The medicine can be used with caution in elderly patients (aged above 65 years) after consulting the doctor. The most common side effects of receiving TAXONAB 100MG INJECTION are minor allergic reactions (such as flushing, rash, itching), shortness of breath, sore throat/mouth ulcers, diarrhea, nausea, vomiting and/or loss of hair. Consult your doctor if any of these symptoms worsen. USES OF TAXONAB 100MG INJECTION Manage ovarian and breast cancer. Manage advanced NSCLC (non-small cell lung cancer) Manage AIDS-related Kaposi’s sarcoma in affected individuals. HOW TAXONAB 100MG INJECTION WORKS TAXONAB 100MG INJECTION works by interfering with the microtubule structures in the cell (substance which aids cancer cells to divide and multiply) thus inhibiting the growth of cancer cells and managing its spread in affected individuals. DIRECTIONS FOR USE TAXONAB 100MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF TAXONAB 100MG INJECTION COMMON minor allergic reactions such as flushing, rash and/or itching infections such as upper respiratory infection, urinary tract infection shortness of breath sore throat/mouth ulcers, sore and red mouth diarrhea, nausea, vomiting loss of hair pain in the muscles, cramps, joints fever, severe chills, headache, dizziness, tiredness, looking pale bleeding, bruising more easily than normal signs of peripheral neuropathy such as numbness, tingling/weakness in arms and legs temporary mild nail change and skin changes reactions at injection sites such as localized swelling, pain and/or redness of the skin. UNCOMMON septic shock (severe drop in blood pressure) due to infections racing heartbeat, rapid beating of the heart, respiratory distress, heart attack, heart block fatigue, sweating, fainting, significant allergic reactions, phlebitis (inflammation of a vein), swelling of the face, lips, mouth, tongue and/or throat back pain, chest pain, pain around hands and feet, chills, abdominal pain. RARE febrile neutropenia (type of fever) due to low white blood cell count associated with fever and increased risk of infection motor neuropathy (disease that affects your body’s motor nerves) pulmonary embolism (blockade of lung artery), lung fibrosis (damaged/scarred lung tissue), interstitial pneumonia (scarring of lung tissue), pleural effusion (build of fluid between lungs and chest) bowel obstruction, bowel perforation, inflammation of colon, inflammation of the pancreas (pancreatitis) skin redness peritonitis (inflammation of abdominal layer) fever, dehydration, weakness anaphylactic reactions (life threatening allergic reaction). HOW TO MANAGE SIDE EFFECTS Diarrhea: Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult your doctor and inform them if the symptom gets worse.

Clocivir 500 Injection is an intravenous formulation containing Acyclovir 500 mg, manufactured by American Remedies. It is primarily used to treat severe viral infections caused by herpes viruses. ________________________________________ 🩺 Uses of Clocivir 500 Injection Clocivir 500 Injection is indicated for: • Herpes Simplex Infections in Immunocompromised Patients: Including severe primary or non-primary genital herpes. • Herpes Simplex Encephalitis: A serious brain infection caused by the herpes simplex virus. • Neonatal Herpes Simplex Virus Infection: In newborns. • Varicella-Zoster Infections in Immunocompromised Patients: Such as severe cases of chickenpox or shingles. • Severe Herpes Zoster (Shingles): In immunocompetent patients with very severe acute local or systemic manifestations. ________________________________________ 💊 Mechanism of Action Acyclovir, the active ingredient in Clocivir, is a synthetic purine nucleoside analogue. It exerts its antiviral effects by inhibiting viral DNA synthesis, thereby preventing the replication of herpes viruses. Acyclovir is converted to its active form, Acyclovir Triphosphate, within infected cells, which then interferes with viral DNA polymerase. ________________________________________ ⚠️ Precautions • Administration: Clocivir 500 Injection should be administered by a healthcare professional through slow intravenous infusion over a 1-hour period to minimize the risk of kidney damage. • Hydration: Adequate hydration is essential during treatment to prevent dehydration and kidney damage. • Kidney Function: Use with caution in patients with pre-existing kidney conditions. • Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Nitrocan 25 Injection is a brand of Nitroglycerin Injection 25 mg/5 mL, manufactured by American Remedies. It is primarily used in hospital settings for the management of certain cardiovascular conditions. ________________________________________ ✅ Primary Uses Nitrocan 25 Injection is indicated for: • Angina Pectoris: To treat and prevent chest pain caused by reduced blood flow to the heart. • Acute Myocardial Infarction (Heart Attack): To alleviate chest pain and improve blood flow to the heart muscle. Hypertension During Surgery: To control high blood pressure during and after surgical procedures. • Congestive Heart Failure: To reduce the workload on the heart and improve symptoms. ________________________________________ ⚙️ Mechanism of Action Nitroglycerin is a nitrate that, once administered, is converted into nitric oxide in the body. This leads to the relaxation and dilation of blood vessels, improving blood flow and reducing the heart's workload. ________________________________________ ⚠️ Precautions • Contraindications: Should not be used in patients with severe anemia, hypotension, or those taking medications for erectile dysfunction (e.g., sildenafil, tadalafil) due to the risk of a significant drop in blood pressure. • Monitoring: Requires careful monitoring of blood pressure and heart rate during administration. • Administration: Administered intravenously under medical supervision; dosage and duration are determined by the healthcare provider. ________________________________________ 💊 Common Side Effects • Headache • Dizziness or lightheadedness • Hypotension (low blood pressure) • Nausea or vomiting • Flushing

Milrican 10 is a brand of Milrinone Lactate Injection, manufactured by American Remedies. Milrinone is a phosphodiesterase-3 (PDE3) inhibitor that serves as both an inotropic agent and a vasodilator. ________________________________________ ✅ Primary Uses of Milrican 10 Milrican 10 is indicated for the short-term intravenous treatment of: • Severe congestive heart failure: Particularly in patients unresponsive to conventional therapies. • Acute decompensated heart failure: Including low output states following cardiac surgery. It is commonly used in intensive care units or during cardiac procedures to support heart function. ________________________________________ ⚙️ Mechanism of Action Milrinone works by inhibiting PDE3, leading to increased cyclic AMP (cAMP) levels in cardiac and vascular smooth muscle cells. This results in: • Increased myocardial contractility: Enhancing the heart's ability to pump blood. • Vasodilation: Relaxing blood vessels, which reduces the heart's workload and improves blood flow. ________________________________________ ⚠️ Important Considerations • Administration: Milrican 10 should only be administered intravenously under the supervision of a healthcare professional. • Monitoring: Patients receiving Milrican 10 require close monitoring of blood pressure, heart rate, and kidney function. • Contraindications: Not recommended for patients with severe dehydration, electrolyte imbalances, or known hypersensitivity to milrinone. • Pregnancy and Breastfeeding: Consult a doctor before use if pregnant or breastfeeding.

Vantox-CP 1gm Injection is an antibiotic used in the treatment of severe bacterial infections in hospitalized patients. It is effective against infections of the respiratory tract (e.g. pneumonia), urinary tract, skin and soft tissues, bones and joints, heart, blood, and others. Vantox-CP 1gm Injection is also used for the prevention of infection in some high-risk patients undergoing surgical procedures. It works by stopping the growth of bacteria and is useful for treating adults as well as children. It is a narrow-spectrum antibiotic that only covers the gram-positive type of bacteria. This medicine is administered slowly by a drip (infusion) into a vein, under the supervision of a healthcare professional. A rapid infusion can lead to reactions such as low blood pressure, wheezing, shortness of breath, or itching. It may also be combined with other antibiotics to treat additional types of bacteria. Some people may develop local injection site reactions like pain, swelling, and redness. However, these are usually minor and temporary. Other side effects like wheezing, kidney (renal) injury, shortness of breath, flushing (sense of warmth in the face, ears, neck, and trunk) and decreased blood pressure may be seen occasionally.

Vantox-CP 500mg Injection is an antibiotic used in the treatment of severe bacterial infections in hospitalized patients. It is effective against infections of the respiratory tract (e.g. pneumonia), urinary tract, skin and soft tissues, bones and joints, heart, blood, and others. Vantox-CP 500mg Injection is also used for the prevention of infection in some high-risk patients undergoing surgical procedures. It works by stopping the growth of bacteria and is useful for treating adults as well as children. It is a narrow-spectrum antibiotic that only covers the gram-positive type of bacteria. This medicine is administered slowly by a drip (infusion) into a vein, under the supervision of a healthcare professional. A rapid infusion can lead to reactions such as low blood pressure, wheezing, shortness of breath, or itching. It may also be combined with other antibiotics to treat additional types of bacteria. Some people may develop local injection site reactions like pain, swelling, and redness. However, these are usually minor and temporary. Other side effects like wheezing, kidney (renal) injury, shortness of breath, flushing (sense of warmth in the face, ears, neck, and trunk) and decreased blood pressure may be seen occasionally. Inform your doctor if you have a history of an allergic reaction to this medication in the past. Your doctor may regularly monitor your kidney function and your hearing while you are taking this medicine. Some people may be advised blood tests to check the level of this medicine in their blood. Consult your doctor if you are pregnant or breastfeeding before taking this medicine.

Nipress 50mg Injection Marketer Samarth Life Sciences Pvt Ltd SALT COMPOSITION Nitroprusside (50mg) Storage Store below 30°C Uses of Nipress Injection Angina (heart-related chest pain) Heart Failure Coronary artery disease Hypertensive emergency Anal fissure Product introduction Nipress 50mg Injection is a medicine used in the immediate treatment of hypertensive emergency (severely increased blood pressure) and acute heart failure. It brings about an immediate reduction in blood pressure and the workload of the heart. Nipress 50mg Injection is given as a drip into the vein under the supervision of a doctor. Your doctor is the right person to decide the dose and duration, hence do not try to self-administered the injection at home. Regular monitoring of blood pressure is required while on treatment. Decreased blood pressure (hypotension) may occur as a side effect of this medicine. Inform your doctor if you are pregnant, planning to conceive or breastfeeding. It is also advisable to avoid medication like sildenafil or tadalafil while on treatment as it may cause a sudden lowering of blood pressure. Side effects of Nipress Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Nipress Cyanide poisoning Decreased blood pressure How to use Nipress Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Nipress Injection works Nipress 50mg Injection is a vasodilator. It works by relaxing the muscles in your blood vessels to help them widen and results in the lowering of blood pressure. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Nipress 50mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Nipress 50mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Nipress 50mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. warnings Driving CONSULT YOUR DOCTOR It is not known whether Nipress 50mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. warnings Kidney SAFE IF PRESCRIBED Nipress 50mg Injection is safe to use in patients with kidney disease. No dose adjustment of Nipress 50mg Injection is recommended. However, talk to your doctor if you have any underlying kidney disease.

Norbit Injection Marketer Celon Laboratories Ltd SALT COMPOSITION Norepinephrine (2mg) Storage Store below 30°C Uses of Norbit Injection Low blood pressure Severe allergic reactions Glaucoma Decreased blood pressure Local anesthesia (Numb tissues in a specific area) Bleeding Allergic conditions Cardiac arrest Product introduction Norbit Injection is used to treat hypotension (low blood pressure) that may occur due to causes such as sepsis (infection). It helps to increase blood pressure by narrowing the blood vessels of the heart. It may be used to revive a patient with cardiac arrest. Norbit Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. Doctor may closely monitor your blood pressure and heart rate till you became stable. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. Your doctor may advise for regular monitoring of blood pressure. It may cause side effects like high blood pressure, headache, and insomnia (difficulty in sleeping). You must inform the doctor if you are suffering from diabetes, liver, heart or kidney disease. Also, let your doctor know about all the other medications that you are using regularly. This medicine is not usually recommended during pregnancy or breastfeeding, so always consult your doctor before taking it. Benefits of Norbit Injection In Low blood pressure Norbit Injection is used to normalise decreased blood pressure (hypotension) which may occur all of a sudden during an operation, severe infection (sepsis) or due to an emergency condition (cardiac arrest). This medicine helps to bring back the blood pressure within normal range and therefore prevents any sudden fall or even serious complications that might have otherwise followed due to low blood pressure. Side effects of Norbit Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Norbit Systemic hypertension (high blood pressure) Headache Restlessness Insomnia (difficulty in sleeping) Palpitations Tremors How to use Norbit Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Norbit Injection works NA. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Norbit Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Norbit Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Norbit Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. warnings Driving NOT RELEVANT Not relevant, as Norbit Injection is intended for use in hospitalised patients. warnings Kidney CONSULT YOUR DOCTOR There is limited information available on the use of Norbit Injection in patients with kidney disease. Please consult your doctor. warnings Liver CONSULT YOUR DOCTOR There is limited information available on the use of Norbit Injection in patients with liver disease. Please consult your doctor.

Dobier S 50mg Injection Salt: Dobutamine (50mg) INTRODUCTION ABOUT DOBIER S 50MG INJECTION DOBIER S 50MG INJECTION contains Dobutamine which belongs to the group of medicines called Cardiac Stimulants. It is used to improve heart functions. It restores heartbeat and blood pressure to normal levels among patients undergoing open heart surgery and in patients having heart failure or any other severe heart conditions that reduces heart rate (such as shock or cardiomyopathies (enlargement of heart muscles)). It can also be used as an alternative to exercise during stress testing (a procedure used to detect heart problems). DOBIER S 50MG INJECTION is suitable for use both in adults and in children (including infants). Before receiving DOBIER S 50MG INJECTION inform your doctor if you have asthma or any other respiratory disorders. You must also inform your doctor if you have any allergic conditions or low blood volume as a precaution. DOBIER S 50MG INJECTION is not suitable for stress testing in patients having any heart or blood vessels disorders that hinder blood flow. It is also not recommended for use in pregnant and in breastfeeding women unless considered necessary by the physician. The most common side effects of receiving DOBIER S 50MG INJECTION are fast heartbeat, headache, high or low blood pressure, shortness of breath, inflammation at the injection site, nausea and urge to pass urine. Consult your doctor if any of these side effects worsens. USES OF DOBIER S 50MG INJECTION Improves heart functions by restoring normal heartbeat and blood pressure Manage heart failure Manage shock (cardiogenic or septic shock) Manage any heart conditions that may result in poor circulation around the body (such as cardiomyopathies, open heart surgery) Used as an alternative to exercise during stress testing HOW DOBIER S 50MG INJECTION WORKS DOBIER S 50MG INJECTION is a cardiac stimulant. It stimulates the heart and improves heart functions. It helps your heart to work more effectively by strengthening the pumping action of the heart. It also improves blood circulation around the body by expanding the blood vessels present all over the body. DIRECTIONS FOR USE DOBIER S 50MG INJECTION will be given only by a doctor or by a trained healthcare professional into the vein (intravenously). Your doctor will decide the correct dose, duration of therapy and site of administration for you depending upon your age, body weight and health condition. SIDE EFFECTS OF DOBIER S 50MG INJECTION COMMON increased heart rate chest pain abnormal heartbeat, palpitations high or low blood pressure narrowing of the blood vessels headache wheezing, shortness of breath increase in WBC count in blood increased bleeding tendency urge to pass urine nausea skin rash fever inflammation at the injection site HOW TO MANAGE SIDE EFFECTS Headache: Try to take rest. Apply a pain-relieving balm on your forehead. If the symptom does not improve, consult with your doctor. Nausea: Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your symptom worsens. Skin rash: Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash worsens. Inflammation at the site of injection: Place an ice pack on the injected site. Do not move the affected area frequently. If the symptom worsens, consult your doctor. WARNING & PRECAUTIONS PREGNANCY DOBIER S 50MG INJECTION is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, inform your doctor before receiving this medicine if you are pregnant or think you may be pregnant or planning to have a baby. BREASTFEEDING DOBIER S 50MG INJECTION is not recommended for use in breastfeeding women. Therefore, inform your doctor before receiving this medicine if you are breastfeeding. DRIVING AND USING MACHINES Do not drive or operate any machines if your ability is affected by DOBIER S 50MG INJECTION. ALLERGY Do not receive DOBIER S 50MG INJECTION if you are allergic to Dobutamine. LUNGS DOBIER S 50MG INJECTION should be used with caution in patients with asthma or any allergic or respiratory conditions. Therefore, consult your doctor before receiving it. HEART DISEASE DOBIER S 50MG INJECTION is not recommended for use in patients who have narrowing of blood vessels supplying the heart (coronary artery stenosis) or other heart disorders. It should be used with caution in patients with other heart problems (such as coronary artery disease, or acute heart failure). Therefore, consult your doctor before receiving it. OTHERS DOBIER S 50MG INJECTION is not recommended for use if you: have low blood volume (hypovolaemia) have any disorders in the blood vessels that hinders blood flow Before receiving DOBIER S 50MG INJECTION, inform your physician if you: