INTRODUCTION ABOUT VALCYTE 450MG TABLET VALCYTE 450MG TABLET contains Valganciclovir which belongs to the group of medicines called Antiviral agents. It is used in adults (with acquired immunodeficiency syndrome) to manage cytomegalovirus (CMV) infection of the retina of the eye which generally cause vision problems and blindness. VALCYTE 450MG TABLET is also used in adults and children to manage cytomegalovirus (CMV) infection who are not infected with CMV or who had received an organ transplant from someone who earlier had CMV infection. VALCYTE 450MG TABLET is not recommended for use in patients allergic (hypersensitive) to Valganciclovir, and/or Ganciclovir. Before taking VALCYTE 450MG TABLET, inform your doctor if are undergoing radiotherapy/hemodialysis, and/or suffer from low red blood cell, white blood cell or platelets, kidney/liver problems. VALCYTE 450MG TABLET is not recommended for use in pregnant women unless it is clearly necessary since it may cause harm to the unborn baby. It is also not recommended for use in breastfeeding women. VALCYTE 450MG TABLET should be used with caution in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 65 years and above) after consulting the doctor. The most common side effects of taking VALCYTE 450MG TABLET are oral thrush (fungal infection), headache, shortness of breath, abdominal pain, loss of appetite, nausea, vomiting, and/or diarrhea. Consult your doctor if any of these symptoms worsens. USES OF VALCYTE 450MG TABLET Manage cytomegalovirus (CMV) infection of the retina of the eye in adult patients with acquired immunodeficiency syndrome (AIDS). Prevents cytomegalovirus (CMV) infection who are not infected with CMV or in patients who had received an organ transplant from someone who earlier had CMV infection HOW VALCYTE 450MG TABLET WORKS VALCYTE 450MG TABLET works by managing the multiplication of virus in human cells by decreasing its growth which results in inhibition of production of new virus thus managing and managing the spread of infection to other parts of the body in affected individuals. DIRECTIONS FOR USE Take VALCYTE 450MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF VALCYTE 450MG TABLET COMMON thrush & oral thrush (fungal infection) upper respiratory tract infection such as sinusitis, tonsillitis headache cough, shortness of breath abdominal pain, loss of appetite, nausea/vomiting, diarrhea, weight loss eczema (skin inflammation) tiredness, fever influenza signs of urine infection such as fever, passing urine more often, and/or pain (while passing urine) skin infection signs of mild allergic reaction such as red, itchy skin feeling depressed, anxious or confused trouble sleeping feeling numb/weak in hands/feet changes in sense of touch, tingling/tickling/pricking/burning sensation altered taste, chills eye inflammation/pain or sight problems ear pain signs of low blood pressure such as feeling dizzy/faint difficulty while swallowing constipation, wind, indigestion, stomach pain, swelling of abdomen mouth ulcers night sweats itching, rash hair loss back pain, muscle/joint pain, muscle spasms feeling dizzy, weak/generally unwell UNCOMMON feeling agitated tremor/shaking deafness irregular heartbeat red itchy welt, dry skin blood in urine chest pain RARE Stop taking VALCYTE 450MG TABLET and contact your doctor if you experience any of the following side effects: signs of allergic reaction (anaphylactic shock) such as raised, itchy skin rash, sudden swelling of throat, face, lips/mouth resulting in difficulty while swallowing/breathing, and/or sudden swelling of the hands, feet/ankles. signs of infection (due to low white blood cell count) such as sore throat, mouth ulcer, and/or fever signs of low red blood cell count such as shortness of breath, tiredness, palpitation, and/or pale skin signs of blood infection (sepsis) such as fever, chills, palpitation, confusion, and/or slurred speech signs of low platelet count such as bleeding/bruising, blood in urine/stools, and/or bleeding from gums severely low blood cell count pancreatitis (inflammation of pancreas) associated with severe stomach pain fits hallucinations abnormal thoughts/feelings, losing contact with reality failure of kidney function HOW TO MANAGE SIDE EFFECTS Constipation Try to eat high-fiber foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise (such as going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate managements for constipation.

About the brand Malegra 50 is marketed globally by Sunrise. About the drug Malegra 50 Mg An active ingredient in Malegra 50 is Sildenafil citrate. Sildenafil citrate is used in the treatment for erectile dysfunction treatment (inadequate penile erection during sexual activity), pulmonary hypertension (high pressure in blood vessels of lungs), benign prostatic hyperplasia (enlarged prostate). Manufacturer of Malegra 50 Mg Malegra 50 having 50 mg of sildenafil citrate is manufactured by sunrise. It is mainly marketed and supplied by the company and its associates in India. Strength Malegra 50 having 50 mg of Sildenafil citrate. USA Brands Equivalent to Sildenafil citrate the salt in Malegra 50 Mg Viagra is the USA brand equivalent to Malegra 50 Use of Sildenafil citrate the salt in Malegra 50 Mg It is used to treat erectile dysfunction (ED). In men, it is used to treat the signs of an enlarged prostate. It is used to treat raised pressure in the lungs. It may be given to you for other reasons. Talk with the doctor. Erectile dysfunction: It is a medical condition, in which, proper erection of penis is a problem. Men are not able to erect their penis even during sexual stimulation. This leads to impotency. Malegra 50 helps in relaxing the veins and arteries in penis leading to perfect erection before sexual activity and thus increase the satisfaction level during sexual intercourse Pulmonary Arterial Hypertension: It is a condition in which there is a raised pressure in your lungs. Malegra 50 relax blood vessels in the lungs leads to lowering of blood pressure. Benign prostatic hyperplasia: it is a condition in which your prostate gland is enlarged. Malegra 50 improve the blood flow to the prostate and relax the muscles in the prostate and bladder and thus help in relieving urinary symptoms. Usually, a high dose is used for Pulmonary Arterial Hypertension than the other two indications. How Malegra 50 Mg works Malegra 50 having Sildenafil citrate works by inhibiting the phosphodiesterase type 5 in the body. Thus it stops the degradation of cGMP( Cyclic guanosine monophosphate). Availability of cGMP helps relax the veins in penis and thus helps in erection when there is a need for sexual activity or sexual stimulation. Inhibition of phosphodiesterase type 5 (PDE-5) in smooth muscle of pulmonary blood vessels results in its relaxation of and it helps to reduce the pressure in your lungs. How to take Malegra 50 Mg Malegra 50 having salt Sildenafil citrate shall be taken before 1 hour of sexual intercourse with a glass of water. More information will be directed by your doctor. Hence consult your doctor before having Malegra 50. Sildenafil Dosage Sildenafil citrate the active salt in Malegra 50 is to be taken usually in a dosage which ranges from 25 mg to 100 mg. More specific dose will be directed by your doctor. Hence, do not take Malegra 50 without consulting with your doctor. How long should Malegra 50 Mg be continued Malegra 50 having sildenafil citrate is a need to basis medicine. Consult your doctor regarding the intake and stoppage of the drug. Do not take a decision on your own. Consult your doctor for each possible steps. Dose of Malegra 50 Mg missed The possible chances of missing the dose of the drug is minimal, however, consult your doctor regarding the same. The drug is mainly taken before the actual sexual intercourse, hence missing the dose is rare. Drug interaction with Sildenafil citrate the salt in Malegra 50 Mg Nitrates(Isosorbide dinitrate, isosorbide mononitrate, nitroglycerin) generally react with Sildenafil citrate, the salt present in Malegra 50. Tell your doctor If you are taking any of these drugs: Itraconazole or ketoconazole, riociguat, or ritonavir, rifampin. If you are taking another brand that has the same active ingredient (sildenafil citrate) If you are taking another drug in the same class as of sildenafil citrate (eg: tadalafil) If you are taking any of these drugs-alfuzosin, doxazosin, silodosin, tamsulosin, terazosin When not to take Malegra 50 Mg Do not take Malegra 50 if you have allergic reactions with the salt or excipients. Sildenafil Adverse Effects / Side effects Some patients may have allergic reactions. Inform your doctor if you have any signs of allergic reaction like rash, itching, red-swollen skin, fever, trouble breathing, swollen face etc. Chest pain or pressure A fast heartbeat or a heartbeat that does not feel normal. Dizziness or passing out. Severe headache. Weakness on one side of the body, trouble speaking or thinking, loss of balance, drooping on one side of the face, or blurred eyesight. Change in eyesight. Loss of eyesight. Hearing loss or change in hearing Ringing in ears. Very bad muscle pain, back pain, soreness, or weakness. If you have a painful erection (hard penis) or an erection that lasts for longer than 4 hours, then call your doctor immediately. It should be treated properly otherwise it may cause lasting sex problems. Overdose E

For Dogs: The Dermoscent BIO BALM® for dogs is specifically designed to nourish and promote the repair of dry nose and pads (thickened, rough, cracking skin). It also helps in soothing interdigital irritations. Based on organic-certified ingredients, this balm helps reduce non-infected calluses (pressure point calluses of elbows). Thanks to its water-resistant texture, this nourishing skincare protects pads under all circumstances (sport activities, snow…) For horses: Dermoscent bio balm for horses is a water-resistant balm that nourishes, protects and helps soothe the skin of your horse. The nourishing and water-resistant formula of Dermoscent BIO BALM® for horses, based on organic-certified ingredients, is specifically designed to reduce skin dryness and other thickened zones. It protects and helps soothe areas prone to friction or weakened by muddy conditions (cannons, pasterns).

Aceptor contains Benazepril hydrochloride, an Angiotensin Converting Enzyme (ACE)-inhibitor. ACE inhibitors block an enzyme called Angiotensin Converting Enzyme (ACE) and helps in relaxing (dilatation) of blood vessels, thereby reducing blood pressure. Aceptor increases survival of patients with Dilated Cardiomyopathy (DCM) and Mitral valve disease (MMVD). It also reduces protein loss associated with Chronic Kidney Disease (CKD), decreases left ventricular wall thickness in Hypertrophic Cardiomyopathy (HCM) in cats and helps in the treatment of hypertension.

Tropicamide Ophthalmic Solution USP 0.5% is a sterile, anticholinergic eye drop used primarily for diagnostic purposes in ophthalmology. ________________________________________ 🔍 Primary Uses 1. Pupillary Dilation (Mydriasis): Tropicamide 0.5% is employed to dilate the pupil, facilitating detailed examination of the retina, optic nerve, and other internal eye structures during procedures like fundoscopy and slit-lamp assessments. 2. Cycloplegia: It temporarily paralyzes the ciliary muscle, preventing accommodation (focusing), which is useful in refractive error assessments. 3. Management of Uveitis: Tropicamide 0.5% is utilized in treating conditions like acute and subacute iridocyclitis, chronic iridocyclitis, and to prevent adhesions and disruptions of the iris and ciliary body. ________________________________________ ⚠️ Side Effects While generally well-tolerated, potential side effects may include: • Temporary stinging or burning sensation upon instillation • Blurred vision • Sensitivity to light (photophobia) • Dry mouth • Headache • Nausea or vomiting • Pale skin • Central nervous system disturbances, including agitation or confusion, especially in pediatric patients ________________________________________ 🧪 Usage Instructions • Administration: Instill one or two drops into the affected eye(s) as directed by your healthcare provider. • Contact Lenses: Remove contact lenses before application. • Hygiene: Avoid touching the dropper tip to any surface to prevent contamination. • Post-application: Apply gentle pressure to the inner corner of the eye for 1–3 minutes to minimize systemic absorption. ________________________________________ ⚠️ Precautions • Driving and Operating Machinery: Avoid engaging in activities requiring clear vision, such as driving, until the effects of the medication have worn off. • Pediatric Use: Use with caution in children, as anticholinergic drugs may cause CNS disturbances. • Pregnancy and Breastfeeding: Consult your healthcare provider before use during pregnancy or while breastfeeding.

Biotrav (Travoprost) Ophthalmic Solution Biotrav is a prescription eye drop containing travoprost, a prostaglandin analog used to lower intraocular pressure (IOP) in individuals with open-angle glaucoma or ocular hypertension. ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common type of glaucoma characterized by gradual loss of vision due to increased IOP. • Ocular Hypertension: Elevated IOP without optic nerve damage, which can lead to glaucoma if untreated. ________________________________________ 💊 Dosage and Administration • Recommended Dosage: Instill one drop into the affected eye(s) once daily in the evening. • Application Tips: o Wash hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to travoprost or any component of the formulation. o Active or suspected ocular infections. o History of hypersensitivity to prostaglandin analogs. • Cautions: o Use with caution in patients with a history of uveitis, macular edema, or retinal vein occlusion. o May cause changes in eye color, eyelash growth, and skin pigmentation around the eyes. o Consult a healthcare provider before use if pregnant, planning to become pregnant, or breastfeeding. ________________________________________ 🧪 Mechanism of Action Travoprost works by increasing the outflow of aqueous humor through the trabecular meshwork and uveoscleral pathways, thereby reducing IOP. This helps prevent damage to the optic nerve and loss of vision associated with glaucoma and ocular hypertension.

Biotrav-T (Travoprost and Timolol Maleate) Ophthalmic Solution is a prescription eye drop used to manage elevated intraocular pressure (IOP) in individuals with open-angle glaucoma or ocular hypertension. It combines two medications—travoprost (a prostaglandin analog) and timolol maleate (a non-selective beta-blocker)—to reduce IOP through complementary mechanisms. ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common form of glaucoma characterized by gradual loss of vision due to increased IOP. • Ocular Hypertension: Elevated IOP without optic nerve damage, which can lead to glaucoma if untreated. ________________________________________ 💊 Dosage and Administration • Recommended Dosage: Instill one drop into the affected eye(s) once daily, preferably in the evening. • Application Tips: o Wash hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Active or suspected ocular infections. o History of hypersensitivity to beta-blockers. • Cautions: o Use with caution in patients with cardiovascular or pulmonary diseases, as timolol may exacerbate conditions like asthma, bradycardia, or heart block. o Monitor for potential systemic absorption effects, including hypotension or bradycardia. o Consult a healthcare provider before use if pregnant, planning to become pregnant, or breastfeeding. ________________________________________

Tobi-D (Tobramycin with Dexamethasone) Eye Drops is a prescription ophthalmic solution combining an antibiotic and a corticosteroid to treat specific bacterial eye infections accompanied by inflammation. ________________________________________ ✅ Primary Uses Tobi-D is primarily used for: • Bacterial Conjunctivitis: Infection of the conjunctiva (the membrane covering the white part of the eye and the inner surface of the eyelids). • Keratitis: Infection of the cornea. • Post-surgical Infections: Prophylactic treatment or management of infections following eye surgeries. It addresses both the infection and the inflammation associated with these conditions. ________________________________________ 💊 Dosage and Administration • Standard Dosage: Instill 1–2 drops into the affected eye(s) every 4–6 hours, or as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Contraindications and Cautions • Contraindications: o Hypersensitivity to tobramycin, dexamethasone, or any component of the formulation. o Active viral infections of the eye, such as herpes simplex keratitis. o Untreated fungal or mycobacterial infections of the eye. • Cautions: o Use with caution in patients with a history of glaucoma, as corticosteroids can increase intraocular pressure. o Prolonged use may lead to cataract formation or secondary ocular infections. o Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. ________________________________________ 🧪 Mechanism of Action • Tobramycin: An aminoglycoside antibiotic that inhibits bacterial protein synthesis, leading to bacterial cell death. • Dexamethasone: A corticosteroid that reduces inflammation by inhibiting the release of inflammatory mediators. Together, these components address both the infection and the inflammation associated with certain eye conditions.

Tobi-F (Tobramycin Sulphate and Fluorometholone) Ophthalmic Solution is a prescription eye drop that combines an antibiotic and a corticosteroid to treat specific eye conditions. ________________________________________ ✅ Primary Uses Tobi-F is primarily used to manage inflammatory eye conditions where a steroid is indicated and where there is a risk of or existing superficial bacterial infection. The combination of tobramycin and fluorometholone addresses both the infection and the inflammation. ________________________________________ 💊 Dosage and Administration • Standard Dosage: Instill 1–2 drops into the affected eye(s) every 4–6 hours, or as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Contraindications and Cautions • Contraindications: o Hypersensitivity to tobramycin, fluorometholone, or any component of the formulation. o Active viral infections of the eye, such as herpes simplex keratitis. • Untreated fungal or mycobacterial infections of the eye. • Cautions: o Use with caution in patients with a history of glaucoma, as corticosteroids can increase intraocular pressure. o Prolonged use may lead to cataract formation or secondary ocular infections. o Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.