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'lactamase inhibitor'

Items tagged with 'lactamase inhibitor'

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General Medicine

Pipracan 4.5 Injection is a combination antibiotic medication containing Piperacillin (4 g) and Tazobactam (0.5 g). This formulation is used to treat a wide range of serious bacterial infections that may not respond to other antibiotics. ________________________________________ 🔹 Common Uses Pipracan 4.5 Injection is prescribed for: • Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) • Urinary tract infections (UTIs) • Intra-abdominal infections (e.g., peritonitis) • Skin and soft tissue infections, including diabetic foot infections • Gynecological infections, such as uterine infections • Bone and joint infections • Bloodstream infections (bacteremia) It is also used for prophylactic treatment in surgical procedures to prevent infections. ________________________________________ 🔹 How It Works • Piperacillin is a broad-spectrum penicillin antibiotic that inhibits bacterial cell wall synthesis, leading to bacterial cell death. • Tazobactam is a beta-lactamase inhibitor that protects piperacillin from degradation by beta-lactamase enzymes produced by certain bacteria, thereby enhancing its efficacy. This combination allows Pipracan 4.5 to target a wide array of bacteria, including those resistant to other antibiotics. ________________________________________ 🔹 Administration Pipracan 4.5 Injection is administered intravenously by a healthcare professional. The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient's medical condition. Self-administration is not recommended. ________________________________________ 🔹 Side Effects Common side effects may include: • Nausea or vomiting • Diarrhea • Rash or itching • Pain, redness, or swelling at the injection site Serious side effects are rare but can include allergic reactions, liver enzyme abnormalities, or blood disorders. Seek immediate medical attention if you experience symptoms like difficulty breathing, swelling of the face or throat, or unusual bruising or bleeding. ________________________________________ 🔹 Precautions Before using Pipracan 4.5 Injection, inform your doctor if you have: Allergies to penicillins or beta-lactam antibiotics • Kidney or liver disease • A history of gastrointestinal diseases, such as colitis • Bleeding disorders • Undergoing dialysisUse during pregnancy and breastfeeding should be discussed with your healthcare provider. The medication should only be used if the potential benefits justify the potential risks.

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General Medicine

Ceforzone SB 1.5 Injection is a combination antibiotic formulation containing Cefoperazone (1000 mg) and Sulbactam (500 mg). Manufactured by American Remedies, it is primarily used to treat a wide range of bacterial infections. ________________________________________ 🩺 Uses of Ceforzone SB 1.5 Injection Ceforzone SB 1.5 Injection is indicated for the treatment of various bacterial infections, including: • Respiratory Tract Infections: Such as pneumonia and bronchitis. • Urinary Tract Infections: Including cystitis and pyelonephritis. • Intra-abdominal Infections: Such as peritonitis and abscesses. • Skin and Soft Tissue Infections: Including cellulitis and wound infections. • Bone and Joint Infections: Such as osteomyelitis and septic arthritis. • Meningitis: Infection of the membranes covering the brain and spinal cord. • Pelvic Inflammatory Disease: Infection of the female reproductive organs. • Gonorrhea: A sexually transmitted infection. Septicemia: Bloodstream infection. Surgical Prophylaxis: To prevent infections associated with major surgeries. ________________________________________ 💊 Mechanism of Action • Cefoperazone: A third-generation cephalosporin antibiotic that inhibits the synthesis of the bacterial cell wall, leading to cell lysis and death. Sulbactam: A beta-lactamase inhibitor that protects cefoperazone from enzymatic degradation by bacterial beta-lactamases, thereby enhancing its antibacterial activity. ________________________________________ ⚠️ Precautions • Allergy: Inform your healthcare provider if you have a history of allergic reactions to penicillins, cephalosporins, or beta-lactam antibiotics. • Liver or Kidney Impairment: Use with caution in patients with liver or kidney dysfunction. Dosage adjustments may be necessary. • Pregnancy and Breastfeeding: Consult your doctor before use during pregnancy or breastfeeding. • Drug Interactions: Inform your healthcare provider about all other medications you are taking to avoid potential interactions.

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General Medicine

Clavcan 1.2 Injection is a combination antibiotic formulation containing Amoxicillin (1000 mg) and Clavulanic Acid (200 mg). It is manufactured by American Remedies and is primarily used to treat a wide range of bacterial infections. ________________________________________ 🩺 Uses of Clavcan 1.2 Injection Clavcan 1.2 Injection is indicated for the treatment of various bacterial infections, including: • Respiratory Tract Infections: Such as pneumonia and acute exacerbations of chronic bronchitis. Urinary Tract Infections: Including cystitis, urethritis, and pyelonephritis. Skin and Soft Tissue Infections: Such as cellulitis, boils, and wound infections. Bone and Joint Infections: Including osteomyelitis. • Middle Ear Infections: Such as otitis media. Tonsillitis and Sinusitis: Infections of the tonsils and sinuses. Intra-abdominal Infections: Including peritonitis and abscesses. • Dental Infections: Such as dental abscesses. • Genital Infections in Females: Including pelvic inflammatory disease. • Prophylaxis: To prevent infections associated with major surgeries of the heart, joints, kidney, head and neck, stomach, biliary tract, intestine, and pelvic region. ________________________________________ 💊 Mechanism of Action • Amoxicillin: A penicillin-type antibiotic that inhibits the synthesis of bacterial cell walls, leading to bacterial cell death. • Clavulanic Acid: A beta-lactamase inhibitor that prevents bacterial enzymes from breaking down amoxicillin, thereby enhancing its effectiveness against resistant bacteria. ________________________________________ ⚠️ Precautions • Allergy: Inform your doctor if you have a history of allergic reactions to penicillin or other antibiotics. • Liver or Kidney Disease: Use with caution in patients with liver or kidney impairments. • Pregnancy and Breastfeeding: Consult your doctor before use during pregnancy or breastfeeding. • Drug Interactions: Inform your healthcare provider about all other medications you are taking to avoid potential interactions.

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General Medicine

Aone SB 1.5 gm Injection is a combination antibiotic manufactured by American Remedies. It contains Ceftriaxone (1000 mg) and Sulbactam (500 mg). Ceftriaxone is a third-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis, leading to cell death. Sulbactam is a β-lactamase inhibitor that protects Ceftriaxone from degradation by β-lactamase-producing bacteria, thereby enhancing its effectiveness. ________________________________________ 🩺 Uses of Aone SB 1.5 gm Injection Aone SB 1.5 gm Injection is prescribed for the treatment of various bacterial infections, including: • Lower Respiratory Tract Infections: Such as pneumonia. • Urinary Tract Infections (UTIs): Including both complicated and uncomplicated UTIs. • Intra-abdominal Infections: Such as peritonitis. • Skin and Soft Tissue Infections: Including cellulitis and abscesses. • Bone and Joint Infections: Such as osteomyelitis and septic arthritis. • Septicemia: Bloodstream infections. • Meningitis: Infections of the brain and spinal cord membranes. • Pelvic Inflammatory Disease: Infections of the female reproductive organs. • Endocarditis: Infection of the heart valves. • Surgical Prophylaxis: To prevent infections during or after surgery. ________________________________________ 💊 How It Works Ceftriaxone works by inhibiting the synthesis of bacterial cell walls, leading to the destruction of the bacteria. Sulbactam enhances the activity of Ceftriaxone by inhibiting β-lactamase enzymes that can degrade Ceftriaxone, thereby extending its spectrum of activity against resistant bacteria. ________________________________________ ⚠️ Side Effects Common side effects may include: • Injection site reactions (pain, redness, or swelling). • Diarrhea. • Rash. • Increased liver enzymes. • Low blood platelets. • Changes in white blood cell counts. If any of these side effects persist or worsen, consult your healthcare provider promptly. ________________________________________ ⚠️ Precautions Before using Aone SB 1.5 gm Injection, inform your doctor if you: • Have a history of allergies to cephalosporin antibiotics. • Have liver or kidney disease. • Are pregnant, planning to become pregnant, or breastfeeding. • Are taking any other medications, including over-the-counter drugs and supplements. Your doctor will determine the appropriate dosage and duration of treatment based on your specific condition.

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Cats and Dogs

Carodyl contains the most widely used non-steroidal anti-inflammatory drug – Carprofen. Carprofen works by inhibiting an enzyme called cyclooxygenase (COX). This results in lower production of a substance called prostaglandins. By reducing prostaglandin levels, carprofen helps to control pain. Carprofen is a preferential COX 2 inhibitor, with higher ratio of COX 2 to COX 1 inhibition. This is associated with good pain control (analgesic property) with minimal risk of side effects associated with COX 1 inhibition (minimal risk of bleeding). Carodyl Is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of post-operative pain associated with soft tissue and orthopedic surgeries in dogs.

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Cats and Dogs

Aceptor contains Benazepril hydrochloride, an Angiotensin Converting Enzyme (ACE)-inhibitor. ACE inhibitors block an enzyme called Angiotensin Converting Enzyme (ACE) and helps in relaxing (dilatation) of blood vessels, thereby reducing blood pressure. Aceptor increases survival of patients with Dilated Cardiomyopathy (DCM) and Mitral valve disease (MMVD). It also reduces protein loss associated with Chronic Kidney Disease (CKD), decreases left ventricular wall thickness in Hypertrophic Cardiomyopathy (HCM) in cats and helps in the treatment of hypertension.

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Eye Care

Tropind Plus is a combination ophthalmic solution containing Tropicamide 0.8% and Phenylephrine 5%. This formulation is primarily used for both diagnostic and therapeutic purposes in ophthalmology. 🩺 Primary Uses of Tropind Plus 1. Pupillary Dilation (Mydriasis): The combination of Tropicamide and Phenylephrine effectively dilates the pupil, allowing eye care professionals to conduct thorough examinations of the retina, optic nerve, and other internal structures. 2. Cycloplegia: Tropicamide paralyzes the ciliary muscle, preventing accommodation (focusing), which is useful in refractive error assessments. 3. Uveitis Management: In cases of uveitis, Tropind Plus helps alleviate pain and prevents further spasms of the eye muscles. 4. Preoperative Preparation: Before surgeries like cataract extraction or retinal procedures, dilating the pupil is essential for clear visualization of the posterior segment. 5. Retinal Imaging: Facilitates procedures such as fundus photography and optical coherence tomography (OCT) by ensuring adequate pupil dilation. ⚙️ How It Works • Tropicamide is a parasympatholytic agent that inhibits the contraction of the circular muscle and paralyzes the ciliary muscle, leading to pupil dilation and cycloplegia. Phenylephrine is a sympathomimetic drug that causes contraction of the radial muscle of the iris, contributing to pupil dilation. Together, these agents produce rapid and effective dilation of the pupil, facilitating detailed eye examinations and procedures. ⚠️ Side Effects Common side effects may include: • Eye pain or stinging • Blurred vision • Sensitivity to light (photophobia) • Allergic reactions These effects are typically temporary and resolve shortly after the examination. 🧪 Safety and Precautions • Driving and Operating Machinery: Avoid activities that require clear vision, such as driving, immediately after application, as the solution can cause temporary blurred vision. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or while breastfeeding, as safety data may be limited. • Drug Interactions: Be cautious when using Tropind Plus with certain medications, especially monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants, as interactions may occur.

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General Medicine

Omeecan 40 is a brand of Omeprazole 40 mg Injection, manufactured by American Remedies. Omeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production. The injection form is typically used in hospital settings when oral administration is not feasible. ________________________________________ ✅ Primary Uses Omeecan 40 Injection is indicated for: • Gastroesophageal Reflux Disease (GERD): To treat and manage acid reflux symptoms. • Peptic Ulcers: Including gastric and duodenal ulcers, to promote healing and alleviate symptoms. • Stress Ulcers: To prevent and treat ulcers in critically ill patients. • Zollinger-Ellison Syndrome: A condition characterized by excessive stomach acid production. • Helicobacter pylori Eradication: As part of combination therapy to eliminate H. pylori infection, which can cause ulcers. ________________________________________ ⚙️ Mechanism of Action Omeprazole works by irreversibly inhibiting the proton pump (H+/K+ ATPase enzyme) in the stomach lining, thereby reducing gastric acid secretion. This leads to increased gastric pH, promoting healing of acid-related conditions. ________________________________________ ⚠️ Precautions • Allergy: Do not use if allergic to omeprazole or other PPIs. • Drug Interactions: May interact with medications like clopidogrel, warfarin, and certain HIV medications. • Kidney and Liver Function: Use with caution in patients with impaired kidney or liver function. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. ________________________________________ 💊 Side Effects Common Side Effects: • Headache • Nausea

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