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'inhibiting lactamase enzymes'

Items tagged with 'inhibiting lactamase enzymes'

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General Medicine

Aone SB 1.5 gm Injection is a combination antibiotic manufactured by American Remedies. It contains Ceftriaxone (1000 mg) and Sulbactam (500 mg). Ceftriaxone is a third-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis, leading to cell death. Sulbactam is a β-lactamase inhibitor that protects Ceftriaxone from degradation by β-lactamase-producing bacteria, thereby enhancing its effectiveness. ________________________________________ 🩺 Uses of Aone SB 1.5 gm Injection Aone SB 1.5 gm Injection is prescribed for the treatment of various bacterial infections, including: • Lower Respiratory Tract Infections: Such as pneumonia. • Urinary Tract Infections (UTIs): Including both complicated and uncomplicated UTIs. • Intra-abdominal Infections: Such as peritonitis. • Skin and Soft Tissue Infections: Including cellulitis and abscesses. • Bone and Joint Infections: Such as osteomyelitis and septic arthritis. • Septicemia: Bloodstream infections. • Meningitis: Infections of the brain and spinal cord membranes. • Pelvic Inflammatory Disease: Infections of the female reproductive organs. • Endocarditis: Infection of the heart valves. • Surgical Prophylaxis: To prevent infections during or after surgery. ________________________________________ 💊 How It Works Ceftriaxone works by inhibiting the synthesis of bacterial cell walls, leading to the destruction of the bacteria. Sulbactam enhances the activity of Ceftriaxone by inhibiting β-lactamase enzymes that can degrade Ceftriaxone, thereby extending its spectrum of activity against resistant bacteria. ________________________________________ ⚠️ Side Effects Common side effects may include: • Injection site reactions (pain, redness, or swelling). • Diarrhea. • Rash. • Increased liver enzymes. • Low blood platelets. • Changes in white blood cell counts. If any of these side effects persist or worsen, consult your healthcare provider promptly. ________________________________________ ⚠️ Precautions Before using Aone SB 1.5 gm Injection, inform your doctor if you: • Have a history of allergies to cephalosporin antibiotics. • Have liver or kidney disease. • Are pregnant, planning to become pregnant, or breastfeeding. • Are taking any other medications, including over-the-counter drugs and supplements. Your doctor will determine the appropriate dosage and duration of treatment based on your specific condition.

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General Medicine

Pipracan 4.5 Injection is a combination antibiotic medication containing Piperacillin (4 g) and Tazobactam (0.5 g). This formulation is used to treat a wide range of serious bacterial infections that may not respond to other antibiotics. ________________________________________ 🔹 Common Uses Pipracan 4.5 Injection is prescribed for: • Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) • Urinary tract infections (UTIs) • Intra-abdominal infections (e.g., peritonitis) • Skin and soft tissue infections, including diabetic foot infections • Gynecological infections, such as uterine infections • Bone and joint infections • Bloodstream infections (bacteremia) It is also used for prophylactic treatment in surgical procedures to prevent infections. ________________________________________ 🔹 How It Works • Piperacillin is a broad-spectrum penicillin antibiotic that inhibits bacterial cell wall synthesis, leading to bacterial cell death. • Tazobactam is a beta-lactamase inhibitor that protects piperacillin from degradation by beta-lactamase enzymes produced by certain bacteria, thereby enhancing its efficacy. This combination allows Pipracan 4.5 to target a wide array of bacteria, including those resistant to other antibiotics. ________________________________________ 🔹 Administration Pipracan 4.5 Injection is administered intravenously by a healthcare professional. The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient's medical condition. Self-administration is not recommended. ________________________________________ 🔹 Side Effects Common side effects may include: • Nausea or vomiting • Diarrhea • Rash or itching • Pain, redness, or swelling at the injection site Serious side effects are rare but can include allergic reactions, liver enzyme abnormalities, or blood disorders. Seek immediate medical attention if you experience symptoms like difficulty breathing, swelling of the face or throat, or unusual bruising or bleeding. ________________________________________ 🔹 Precautions Before using Pipracan 4.5 Injection, inform your doctor if you have: Allergies to penicillins or beta-lactam antibiotics • Kidney or liver disease • A history of gastrointestinal diseases, such as colitis • Bleeding disorders • Undergoing dialysisUse during pregnancy and breastfeeding should be discussed with your healthcare provider. The medication should only be used if the potential benefits justify the potential risks.

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Hepatitis Medicine

Tavin 300mg tablet tablet consists of the active substance called Tenofovir Disoproxil Fumarate, which belongs to the class of antiretroviral or antiviral medicine. This medicine treats HIV (human immunodeficiency virus) and HBV (hepatitis B virus) infections. It is a nucleotide reverse transcriptase inhibitor (NRTI) and works by inhibiting the enzymes (HIV reverse transcriptase; hepatitis B DNA polymerase) that are important for virus replication. It should always take in combination with other medicines to treat HIV infection. This tablet is suitable for the adult and adolescents aged from 12 to 18 years. For HIV, this medicine is given to adolescents who have already been medicated with other HIV medicines which are no longer fully effective due to resistance or have caused side effects. This tablet is not been studied in patients over 65 years of age. Do not consume this drug if you have experienced hypersensitivity reactions to Tenofovir disoproxil fumarate or any of its ingredients. During the Tavin 300mg tablet tablet treatment, your doctor may periodically monitor your blood counts, bone mineral density, liver and kidney parameters to prevent serious complications. Report to your doctor if you have had a history of heart failure, pancreatitis, bone disease (osteonecrosis - the death of bone tissue), fractures, liver (chronic hepatitis B or C), or kidney problems.

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Anti Cancer Medicine

Marketer Cipla Ltd SALT COMPOSITION Abiraterone Acetate (250mg) Storage Store below 30°C Uses of Xbira Tablet Sickle cell anemia Prostate cancer Blood cancer (Acute lymphocytic leukemia) Soft tissue sarcoma Hodgkin’s disease Product introduction Xbira 250mg Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy. Xbira 250mg Tablet should not be taken on an empty stomach. Taking it with food may cause side effects. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, fatigue and increased liver enzymes. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Other than this, yellowing of skin, loss of appetite, shortness of breath, dark urine and nausea can happen, which indicate some liver problem. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood. Before taking it, tell your doctor if have high blood pressure, heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment. There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details. Side effects of Xbira Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Xbira Edema (swelling) Vomiting Decreased potassium level in blood Fatigue Anemia (low number of red blood cells) Urinary tract infection Diarrhea High blood pressure Cough Joint swelling How to use Xbira Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xbira 250mg Tablet is to be taken empty stomach. How Xbira Tablet works Xbira 250mg Tablet is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.

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Anti Cancer Medicine

Marketer Cipla Ltd SALT COMPOSITION Abiraterone Acetate (500mg) Storage Store below 30°C Uses of Xbira Tablet Sickle cell anemia Prostate cancer Blood cancer (Acute lymphocytic leukemia) Soft tissue sarcoma Hodgkin’s disease Product introduction Xbira 500 Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy. Xbira 500 Tablet should not be taken on an empty stomach. Taking it with food may cause side effects. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, fatigue and increased liver enzymes. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Other than this, yellowing of skin, loss of appetite, shortness of breath, dark urine and nausea can happen, which indicate some liver problem. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood. Before taking it, tell your doctor if have high blood pressure, heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment. There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details. Side effects of Xbira Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Xbira Edema (swelling) Vomiting Decreased potassium level in blood Fatigue Anemia (low number of red blood cells) Urinary tract infection Diarrhea High blood pressure Cough Joint swelling How to use Xbira Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xbira 500 Tablet is to be taken empty stomach. How Xbira Tablet works Xbira 500 Tablet is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.

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General Medicine

Clavcan 1.2 Injection is a combination antibiotic formulation containing Amoxicillin (1000 mg) and Clavulanic Acid (200 mg). It is manufactured by American Remedies and is primarily used to treat a wide range of bacterial infections. ________________________________________ 🩺 Uses of Clavcan 1.2 Injection Clavcan 1.2 Injection is indicated for the treatment of various bacterial infections, including: • Respiratory Tract Infections: Such as pneumonia and acute exacerbations of chronic bronchitis. Urinary Tract Infections: Including cystitis, urethritis, and pyelonephritis. Skin and Soft Tissue Infections: Such as cellulitis, boils, and wound infections. Bone and Joint Infections: Including osteomyelitis. • Middle Ear Infections: Such as otitis media. Tonsillitis and Sinusitis: Infections of the tonsils and sinuses. Intra-abdominal Infections: Including peritonitis and abscesses. • Dental Infections: Such as dental abscesses. • Genital Infections in Females: Including pelvic inflammatory disease. • Prophylaxis: To prevent infections associated with major surgeries of the heart, joints, kidney, head and neck, stomach, biliary tract, intestine, and pelvic region. ________________________________________ 💊 Mechanism of Action • Amoxicillin: A penicillin-type antibiotic that inhibits the synthesis of bacterial cell walls, leading to bacterial cell death. • Clavulanic Acid: A beta-lactamase inhibitor that prevents bacterial enzymes from breaking down amoxicillin, thereby enhancing its effectiveness against resistant bacteria. ________________________________________ ⚠️ Precautions • Allergy: Inform your doctor if you have a history of allergic reactions to penicillin or other antibiotics. • Liver or Kidney Disease: Use with caution in patients with liver or kidney impairments. • Pregnancy and Breastfeeding: Consult your doctor before use during pregnancy or breastfeeding. • Drug Interactions: Inform your healthcare provider about all other medications you are taking to avoid potential interactions.

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Eye Care

Unibrom Eye Drops 5 ml Active Ingredient: Bromfenac 0.09% Manufacturer: Ajanta Pharma Ltd Uses Postoperative Inflammation: Relieves inflammation and pain after cataract surgery. Ocular Discomfort: Reduces eye discomfort and swelling following eye surgeries. How It Works Bromfenac is a non-steroidal anti-inflammatory drug (NSAID). It works by inhibiting cyclooxygenase (COX) enzymes, reducing the production of prostaglandins, chemicals responsible for causing inflammation and pain in the eyes. How to Use Wash your hands thoroughly before use. Tilt your head back and gently pull down the lower eyelid to create a pocket. Instill the prescribed number of drops into the lower eyelid pocket. Close your eye and gently press the inner corner near the nose for about 1 minute to prevent the drops from draining. Recap the bottle and wash your hands again. Typical Dosage 1 drop in the affected eye(s) once or twice a day, or as prescribed by your doctor. Common Side Effects Mild eye irritation or burning sensation. Temporary blurred vision. Increased sensitivity to light. Eye redness or itching. Precautions Allergies: Avoid if allergic to Bromfenac or other NSAIDs. Contact Lenses: Remove soft contact lenses before applying and wait at least 15 minutes before reinserting them. Pregnancy & Breastfeeding: Consult your doctor before use. Children & Elderly: Use with caution, as safety and effectiveness are not well established in these populations.

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Cats and Dogs

Carodyl contains the most widely used non-steroidal anti-inflammatory drug – Carprofen. Carprofen works by inhibiting an enzyme called cyclooxygenase (COX). This results in lower production of a substance called prostaglandins. By reducing prostaglandin levels, carprofen helps to control pain. Carprofen is a preferential COX 2 inhibitor, with higher ratio of COX 2 to COX 1 inhibition. This is associated with good pain control (analgesic property) with minimal risk of side effects associated with COX 1 inhibition (minimal risk of bleeding). Carodyl Is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of post-operative pain associated with soft tissue and orthopedic surgeries in dogs.

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