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General Medicine

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

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General Medicine

Nezolid 600 Injection is a brand of Linezolid Injection 600 mg/300 mL, manufactured by American Remedies. Linezolid is an antibiotic belonging to the oxazolidinone class, effective against various serious bacterial infections. ________________________________________ ✅ Primary Uses Nezolid 600 Injection is indicated for the treatment of: • Nosocomial Pneumonia: Hospital-acquired pneumonia caused by susceptible strains of bacteria. • Community-Acquired Pneumonia (CAP): Pneumonia acquired outside of healthcare settings. • Complicated Skin and Skin Structure Infections (cSSSIs): Infections involving deeper layers of the skin and underlying tissues. • Vancomycin-Resistant Enterococcus faecium (VRE) Infections: Including cases with concurrent bacteremia. These infections are typically caused by Gram-positive bacteria, including multidrug-resistant strains. ________________________________________ ⚙️ Mechanism of Action Linezolid works by inhibiting bacterial protein synthesis. It binds to the bacterial ribosome, preventing the formation of the initiation complex necessary for protein production, thereby halting bacterial growth. This bacteriostatic action is particularly effective against Gram-positive organisms. ________________________________________ ⚠️ Precautions • Drug Interactions: Avoid concurrent use with monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), and certain other medications due to the risk of serotonin syndrome. • Pre-existing Conditions: Use with caution in patients with a history of seizures, diabetes mellitus, liver cirrhosis, or renal impairment. • Dietary Restrictions: Limit intake of foods high in tyramine (e.g., aged cheeses, cured meats, soy products) to reduce the risk of hypertensive reactions. • Pregnancy and Lactation: Consult a healthcare provider before use during pregnancy or breastfeeding.

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General Medicine

Menacan K3 Injection is a brand name for Menadione Sodium Bisulphite Injection, which is a synthetic form of Vitamin K3. It is primarily used in medical and veterinary settings to address Vitamin K deficiencies and related conditions. ________________________________________ 💉 Medical Uses Menacan K3 Injection is indicated for: • Treatment of Vitamin K Deficiency: Essential for synthesizing clotting factors II, VII, IX, and X in the liver. A deficiency can lead to bleeding disorders. • Management of Hypoprothrombinemia: A condition characterized by low levels of prothrombin, increasing the risk of bleeding • Reversal of Anticoagulant Effects: Used in cases of anticoagulant overdose, particularly when rapid reversal is necessary. • Support in Liver Disease: Beneficial for patients with liver disease where vitamin K absorption is impaired. • Treatment of Malabsorption Syndromes: In patients with conditions that disrupt vitamin K absorption. ________________________________________ ⚠️ Important Considerations • Administration: Should only be administered by a trained healthcare professional. Self-administration is not recommended. • Contraindications: Not suitable for individuals with G6PD deficiency, as it can cause serious side effects. Also, use with caution in patients with liver or kidney disease, or those who are pregnant or breastfeeding. • Side Effects: May include facial flushing, sweating, injection site reactions, hemolysis, and altered taste. These side effects are generally mild and resolve over time.

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General Medicine

Dopacan Injection is a brand of Dopamine Hydrochloride, a potent vasopressor and inotropic agent used in critical care settings to manage various cardiovascular conditions. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dopacan Injection is indicated for: • Shock Management: Including septic shock, cardiogenic shock, and hypovolemic shock. • Acute Heart Failure: To improve cardiac output and perfusion. • Severe Hypotension: Especially in patients unresponsive to volume resuscitation. • Renal Protection: To enhance renal blood flow and urine output in certain critically ill patients. Dopamine works by stimulating dopaminergic and beta-adrenergic receptors, leading to increased heart rate, contractility, and renal perfusion. At higher doses, it also stimulates alpha-adrenergic receptors, causing vasoconstriction and increased blood pressure. ________________________________________ ⚙️ Dosage and Administration Dopacan Injection is administered intravenously, with the dosage tailored to the patient's condition and response: • Low Dose (1–5 mcg/kg/min): Primarily stimulates dopaminergic receptors, increasing renal blood flow and urine output. • Medium Dose (5–15 mcg/kg/min): Stimulates beta-1 adrenergic receptors, enhancing heart rate and contractility. • High Dose (15–50 mcg/kg/min): Stimulates alpha-1 adrenergic receptors, leading to vasoconstriction and increased blood pressure. Continuous monitoring of blood pressure, heart rate, and urine output is essential during administration. ________________________________________ ⚠️ Precautions and Contraindications Before using Dopacan Injection, inform your healthcare provider if you have: • Allergies to dopamine or other components of the injection. • A history of heart rhythm disorders or coronary artery disease. • Pheochromocytoma (a rare tumor of the adrenal glands). • Diabetes, asthma, or sulfite allergies. • Circulatory disorders such as Raynaud's disease or Buerger's disease. • Recent use of monoamine oxidase inhibitors (MAOIs). This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. ________________________________________ 💊 Side Effects Common side effects may include: • Palpitations or increased heart rate. • Nausea and vomiting. • Headache. • Difficulty breathing. • Gangrene (in rare cases, due to excessive vasoconstriction). Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.

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General Medicine

Dexacan Injection contains Dexamethasone Sodium Phosphate, a potent corticosteroid used to manage various inflammatory, allergic, and autoimmune conditions. It is typically administered in hospital settings under medical supervision. ________________________________________ 🩺 Medical Uses Dexacan Injection is indicated for: • Adrenal Insufficiency: To replace deficient corticosteroids in conditions like Addison's disease. • Severe Allergic Reactions: Including anaphylaxis and angioedema. • Autoimmune Disorders: Such as rheumatoid arthritis, lupus, and vasculitis. • Inflammatory Conditions: Including ulcerative colitis, Crohn's disease, and certain skin disorders. • Neurological Conditions: For managing cerebral edema and certain types of meningitis. • Endocrine Disorders: As a diagnostic tool in Cushing's syndrome. • Shock Management: Particularly in cases of septic shock, often as an adjunct to other therapies. It works by suppressing inflammation and modulating the immune response. This is achieved through its glucocorticoid activity, which reduces the production of inflammatory mediators. ________________________________________ ⚙️ Dosage and Administration Dexacan Injection is administered intravenously (IV) or intramuscularly (IM) by healthcare professionals. The dosage varies based on the specific condition being treated and the patient's response. For instance, in cerebral edema, an initial IV dose of 10 mg may be followed by 4 mg IM every six hours. ________________________________________ ⚠️ Precautions and Contraindications Before using Dexacan Injection, inform your healthcare provider if you have: • Allergies to dexamethasone or other corticosteroids. • Infections, as corticosteroids can suppress the immune system. • Gastrointestinal issues, such as ulcers. • Cardiovascular diseases, including hypertension. • Diabetes, as corticosteroids can affect blood sugar levels. • Osteoporosis or other bone disorders. Use during pregnancy or breastfeeding should be discussed with a healthcare provider. ________________________________________ 💊 Side Effects Common side effects may include: • Increased appetite and weight gain. • Fluid retention and swelling. • Elevated blood pressure. • Mood swings or psychological effects. • Gastrointestinal discomfort. Long-term use can lead to more serious effects, such as osteoporosis, cataracts, and increased susceptibility to infections. ________________________________________

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General Medicine

Dexacan Injection contains Dexamethasone Sodium Phosphate, a potent corticosteroid used to manage various inflammatory, allergic, and autoimmune conditions. It is typically administered in hospital settings under medical supervision. ________________________________________ 🩺 Medical Uses Dexacan Injection is indicated for: • Adrenal Insufficiency: To replace deficient corticosteroids in conditions like Addison's disease. • Severe Allergic Reactions: Including anaphylaxis and angioedema. • Autoimmune Disorders: Such as rheumatoid arthritis, lupus, and vasculitis. • Inflammatory Conditions: Including ulcerative colitis, Crohn's disease, and certain skin disorders. • Neurological Conditions: For managing cerebral edema and certain types of meningitis. • Endocrine Disorders: As a diagnostic tool in Cushing's syndrome. • Shock Management: Particularly in cases of septic shock, often as an adjunct to other therapies. It works by suppressing inflammation and modulating the immune response. This is achieved through its glucocorticoid activity, which reduces the production of inflammatory mediators. ________________________________________ ⚙️ Dosage and Administration Dexacan Injection is administered intravenously (IV) or intramuscularly (IM) by healthcare professionals. The dosage varies based on the specific condition being treated and the patient's response. For instance, in cerebral edema, an initial IV dose of 10 mg may be followed by 4 mg IM every six hours. ________________________________________ ⚠️ Precautions and Contraindications Before using Dexacan Injection, inform your healthcare provider if you have: • Allergies to dexamethasone or other corticosteroids. • Infections, as corticosteroids can suppress the immune system. • Gastrointestinal issues, such as ulcers. • Cardiovascular diseases, including hypertension. • Diabetes, as corticosteroids can affect blood sugar levels. • Osteoporosis or other bone disorders. Use during pregnancy or breastfeeding should be discussed with a healthcare provider. ________________________________________ 💊 Side Effects Common side effects may include: • Increased appetite and weight gain. • Fluid retention and swelling. • Elevated blood pressure. • Mood swings or psychological effects. • Gastrointestinal discomfort. Long-term use can lead to more serious effects, such as osteoporosis, cataracts, and increased susceptibility to infections. ________________________________________

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General Medicine

CPM Injection refers to Chlorpheniramine Maleate Injection, a first-generation antihistamine commonly used in clinical settings to manage allergic reactions and related conditions. It is available in various strengths, such as 4 mg, 10 mg, and 20 mg per vial, and is administered via intravenous (IV) or intramuscular (IM) injection. ________________________________________ 🩺 Medical Uses CPM Injection is employed to treat a range of allergic and hypersensitivity conditions, including: • Acute Allergic Reactions: Such as anaphylaxis, where rapid intervention is crucial. • Chronic Allergies: Including hay fever, allergic rhinitis, and conjunctivitis. • Skin Conditions: Like urticaria (hives), angioedema (swelling), and pruritus (itching). • Pre-Medication: Administered before blood transfusions or certain medications to prevent allergic reactions. • Motion Sickness: To alleviate symptoms associated with nausea and vomiting. • Common Cold Symptoms: Such as sneezing and runny nose. Its rapid onset makes it particularly valuable in emergency and hospital settings. ________________________________________ ⚙️ Mechanism of Action Chlorpheniramine Maleate works by blocking histamine receptors (H1 receptors) in the body. Histamine is a chemical involved in allergic responses; by inhibiting its action, CPM reduces symptoms like itching, swelling, and redness. ________________________________________ 💉 Administration and Dosage CPM Injection is administered by healthcare professionals: • Intravenous (IV) Injection: For rapid onset of action. • Intramuscular (IM) Injection: For sustained release and longer duration of effect. The dosage and frequency depend on the specific condition being treated, the patient's age, weight, and overall health status. It is crucial to follow the prescribing healthcare provider's instructions. ________________________________________ ⚠️ Precautions and Contraindications Before administering CPM Injection, inform the healthcare provider if the patient has: • Allergy: To chlorpheniramine or any other antihistamines. • Medical Conditions: Such as glaucoma, high blood pressure, or gastrointestinal issues. • Pregnancy or Breastfeeding: Discuss potential risks and benefits. CPM may cause drowsiness; therefore, activities requiring alertness, like driving, should be avoided during treatment. Alcohol consumption should also be limited, as it can exacerbate drowsiness. ________________________________________ ⚠️ Side Effects Common side effects may include: • Drowsiness or sedation. • Dizziness or lightheadedness. • Dry mouth. • Blurred vision. • Nausea or vomiting. If any side effects persist or worsen, consult a healthcare provider promptly.

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General Medicine

Atranium 50 mg Injection is a neuromuscular blocking agent containing Atracurium Besylate. It is primarily used in medical settings to facilitate muscle relaxation during surgical procedures and in intensive care units (ICU) for patients requiring mechanical ventilation. ________________________________________ 🩺 Uses of Atranium 50 mg Injection • General Anesthesia: Atranium is administered to relax skeletal muscles during surgeries, aiding in endotracheal intubation and ensuring muscle immobility. • Intensive Care Unit (ICU): It assists in controlled ventilation for ICU patients who need mechanical support for breathing. ________________________________________ 💊 Mechanism of Action Atranium works by blocking the transmission of nerve impulses to skeletal muscles, leading to muscle relaxation. This effect is crucial during surgeries and in ICU settings where muscle control is necessary for patient management. ________________________________________ ⚠️ Side Effects Common side effects may include: • Flushing or redness of the skin • Itching or rash • Injection site reactions (pain, swelling, or redness) • Wheezing or bronchospasm • Rapid heart rate (tachycardia) These side effects are generally mild and transient. However, if they persist or worsen, consult your healthcare provider. ________________________________________ 💰 Price and Availability The price of Atranium 50 mg Injection varies by retailer. For instance, it is available for ₹51.22 per 5 ml vial at Truemeds . Prices can differ based on location and pharmacy. ________________________________________ ⚠️ Precautions Before using Atranium 50 mg Injection, inform your doctor if you: • Have a history of allergies to atracurium or other neuromuscular blocking agents. • Have conditions such as myasthenia gravis, Eaton-Lambert syndrome, or severe electrolyte imbalances. • Are pregnant, planning to become pregnant, or breastfeeding. • Are taking other medications, including over-the-counter drugs and supplements.

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General Medicine

Atranium 25 mg Injection is a neuromuscular blocking agent containing Atracurium Besylate. It is primarily used in medical settings to facilitate muscle relaxation during surgical procedures and in intensive care units (ICU) for patients requiring mechanical ventilation. ________________________________________ 🩺 Uses of Atranium 25 mg Injection • General Anesthesia: Atranium is administered to relax skeletal muscles during surgeries, aiding in endotracheal intubation and ensuring muscle immobility. • Intensive Care Unit (ICU): It assists in controlled ventilation for ICU patients who need mechanical support for breathing. ________________________________________ 💊 Mechanism of Action Atranium works by blocking the transmission of nerve impulses to skeletal muscles, leading to muscle relaxation. This effect is crucial during surgeries and in ICU settings where muscle control is necessary for patient management. ________________________________________ ⚠️ Side Effects Common side effects may include: • Flushing or redness of the skin • Itching or rash • Injection site reactions (pain, swelling, or redness) • Wheezing or bronchospasm • Rapid heart rate (tachycardia) These side effects are generally mild and transient. However, if they persist or worsen, consult your healthcare provider. ________________________________________ ⚠️ Precautions Before using Atranium 25 mg Injection, inform your doctor if you: • Have a history of allergies to atracurium or other neuromuscular blocking agents. • Have conditions such as myasthenia gravis, Eaton-Lambert syndrome, or severe electrolyte imbalances. • Are pregnant, planning to become pregnant, or breastfeeding. • Are taking other medications, including over-the-counter drugs and supplements.

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