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Eye Care

Paristin-Z (Sulphacetamide & Zinc Sulphate) Eye Drops Uses: • Bacterial Eye Infections: Paristin-Z is primarily used to treat bacterial eye infections such as conjunctivitis (pink eye), blepharitis (inflammation of the eyelids), and other superficial eye infections caused by susceptible bacteria. • Eye Irritation Relief: The combination of Sulphacetamide and Zinc Sulphate helps alleviate symptoms like redness, itching, and discharge associated with eye infections. Dosage: • Typical Dosage: Instill 1–2 drops into the affected eye(s) every 3 to 4 hours, or as directed by your healthcare provider. • Application Method: 1. Wash your hands thoroughly before use. 2. Tilt your head back and gently pull down the lower eyelid to create a small pocket. 3. Place the dropper tip near the eye without touching it. 4. Squeeze the prescribed number of drops into the pocket. 5. Close your eye and blink several times to spread the solution evenly. Precautions: • Allergic Reactions: If you experience signs of an allergic reaction such as rash, itching, swelling, or difficulty breathing, discontinue use and consult your doctor immediately. • Contact Lenses: Avoid wearing contact lenses during the course of treatment unless advised otherwise by your healthcare provider. • Pregnancy and Breastfeeding: Consult your doctor before using Paristin-Z if you are pregnant or breastfeeding. Side Effects: • Common Side Effects: o Temporary burning or stinging upon application. o Mild irritation or redness. o Temporary blurred vision. • Serious Side Effects: o Persistent eye pain or swelling. o Worsening of vision. o Signs of an allergic reaction (rash, itching, swelling).

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Allergies

Cort S 100mg Injection belongs to a group of medicines called corticosteroids. It is used to treat a variety of diseases and conditions such as severe allergic reactions, allergic conditions, cancer, and skin and eye disorders. It is used for the treatment of conditions that need a quick response. Cort S 100mg Injection is administered by a healthcare professional. It is usually given to patients who are not able to take the tablet form of the medicine. Taking the medicine can make it harder for your body to fight off infections. Tell your doctor if you have any signs of infection such as a fever or sore throat. Also before taking this medicine, you should let your doctor know all the other medicines you are taking. The most common side effect of this medicine is intense pain and swelling in the joint where the injection was given. This usually gets better after a few days. It may also cause mood changes in some people. If any of these side effects bother you or if you experienced any symptoms which you feel are due to the use of this medicine, let your doctor know.

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HIV/AIDS

INTRODUCTION ABALAM 600/300 is a combination of Abacavir and Lamivudine which belongs to the group of medicines called Anti-viral agents. It is used in the management of HIV infection in adults, adolescents and in children (weighing above 25 kgs). HIV (human immunodeficiency virus) infection is a viral infection that damages our immune system and weakens our body’s ability to fight against various infections. Both abacavir and lamivudine are nucleoside reverse transcriptase inhibitors. They work by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. This prevents further multiplication of viral cells within the body. Also, they can improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. ABALAM 600/300 cannot not manage HIV infection completely. It can reduce only the number of viral cells present in the body and maintains them at a lower level. During management with ABALAM 600/300 your doctor will closely monitor your body weight, blood cholesterol levels and blood sugar levels to reduce the risk of unwanted side effects. Do not take ABALAM 600/300 if you are allergic to abacavir or lamivudine. Before taking ABALAM 600/300 inform your doctor if you have diabetes or any liver (hepatitis C or B infection), kidney or heart problems. If you are already taking ABALAM 600/300 to manage hepatitis B or C infection, do not stop taking it without consulting your doctor. Even if you take ABALAM 600/300, it is important for you to follow certain measures to prevent the spread of infections to the other people (such as avoid having unprotected sexual intercourse or sharing needles or personal items like toothbrush, razors etc with other people). ABALAM 600/300 is not recommended for use in pregnant or breastfeeding women. The most common side effects of taking ABALAM 600/300 are difficulty in sleeping, increased signs of infections, nausea, stomach pain, headache, or dizziness. Consult your doctor if any of these side effects worsens. Also inform your doctor immediately if you experience severe fever with extreme tiredness, sudden changes in body weight or severe stomach pain along with dark urine after taking ABALAM 600/300. USES OF ABALAM 600/300 Manages HIV infection in adults, adolescents and in children (weighing above 25 kgs) HOW ABALAM 600/300 WORKS ABALAM 600/300 is an anti-retroviral medicine. It controls the multiplication of viral cell within the body, by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. It can also improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. DIRECTIONS FOR USE Take ABALAM 600/300 as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. ABALAM 600/300 can be taken with or without meals. Your doctor will decide the correct dose and for how long ABALAM 600/300 must be taken depending upon your age, body weight and severity of the infection. Do not stop taking ABALAM 600/300 without consulting your doctor as it may reduce its effectiveness. SIDE EFFECTS OF ABALAM 600/300 COMMON difficulty in sleeping feeling depressed headache, tiredness, dizziness nausea, diarrhoea fever, skin rash stomach pain loss of appetite irritated or runny nose hair loss UNCOMMON decrease in RBC, WBC, and platelets RARE Stop taking ABALAM 600/300 and contact your doctor immediately if you experience any of the following side effects: signs of allergic reactions (such as skin rash, fever, accompanied with sore throat, cough, nausea, vomiting, stomach pain, diarrhea, tiredness, joint pain, muscle pain, swelling of the neck, difficulty in breathing, mouth ulcers, occasional headaches, inflammation of the eye, low blood pressure, sense of tingling or numbness of hands or feet) pure red cell aplasia (failure of bone marrow to produce new red blood cells) signs of infections (such as fever, headache, stomach-ache, breathing difficulty) signs of auto-immune disorders (such as rapid or irregular heartbeat, tremor, hyperactivity, general weakness) signs of osteonecrosis (death of bone cells causing joint stiffness, pain in the hip, knee or shoulder and difficulty in moving) signs of liver problems (such as yellowing of the skin and whites of the eye, dark urine, light-coloured stools, loss of appetite, nausea, pain, tenderness on the right side of stomach) heart attack changes in body fat (such as increase fat in the shoulder and neck (buffalo hump), breast, and in the middle body or fat loss from the legs, arms, or face)

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HIV/AIDS

Introduction to Xapavir 50mg Tablet Xapavir 50mg Tablet is an antiviral drug belonging to the Integrase strand transfer inhibitor category, containing the active ingredient Dolutegravir. It is used to treat human immunodeficiency virus (HIV) infection. HIV infection is mainly spread by sexual contact with anyone who has the infection or by transfer of infected blood (by sharing injection needles). This drug must be taken with other medicines used to treat HIV infection. This drug is contraindicated in individuals with liver disease. Due to the higher concentration, caution should be taken when administering the drug to individuals with liver impairment. The dosage of this drug may need to be adjusted by your doctor, or it may need to be used with extra monitoring in these individuals to ensure its safety and efficacy. During the early stages of HIV treatment, some patients may experience an inflammatory response to opportunistic infections. This condition, immune reconstitution syndrome, can occur after starting the drug or other antiretroviral therapies. Knowing this possibility and monitoring for any signs of worsening infections or inflammatory symptoms is necessary. Inform your healthcare provider if the symptoms concern you or persist longer than usual. It is necessary for healthcare professionals to carefully monitor patients taking this drug for any signs or symptoms of skin or hypersensitivity reactions, such as rash, blistering, or mucosal lesions. If a severe reaction is suspected, this medicine should be discontinued immediately, and appropriate medical treatment can be initiated. Patients are also advised to report any skin or hypersensitivity reactions to their healthcare provider and to seek medical emergency immediately if they experience any symptoms of a severe reaction. Tell your doctor immediately about all the medications you have been taking recently, including herbal and supplements, before taking this drug. Uses of Xapavir 50mg Tablet Human Immunodeficiency Virus (HIV) Therapeutic Effects of Xapavir 50mg Tablet Xapavir 50mg Tablet works by inhibiting the enzyme integrase, thereby reducing the virus in your body. It also increases a type of white blood cell called CD4 cells which help the body fight infection. Interaction of Xapavir 50mg Tablet with other drugs Inform your healthcare provider about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Xapavir 50mg Tablets and reduce effectiveness by causing undesirable side effects. More Information about Xapavir 50mg Tablet Store Xapavir 50mg Tablet at room temperature (15°to 25°C). Keep the Tablet out of reach of children and pets. How to consume Xapavir 50mg Tablet It is an orally available prescription drug. Your doctor will decide the dose and duration of the drug based on the disease condition and other factors. Always take Xapavir 50mg Tablet as prescribed by your doctor. Take the Tablet with or without food. Do not break, chew, or crush the Tablet. Swallow the whole Tablet with water. Safety Advices for Xapavir 50mg Tablet Image Not Available Pregnancy Suppose you are pregnant or planning for pregnancy during the treatment. Please consult your doctor before taking Xapavir 50mg Tablet. Image Not Available Breast Feeding Breastfeeding is not recommended in patients taking Xapavir 50mg Tablets because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment. Image Not Available Lungs It is unknown whether Xapavir 50mg Tablets can be prescribed for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment. Image Not Available Liver Xapavir 50mg Tablet must be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary for severe liver failure. Inform your doctor if you have liver problems before initiating the therapy Image Not Available Alcohol Consuming alcohol may affect the effectiveness of the Xapavir 50mg Tablet. It is highly advised to stop consuming alcohol if you take this medicine. Image Not Available Driving Driving vehicles or operating heavy machinery is unsafe after taking the Xapavir 50mg Tablet. It may cause dizziness and impair concentration. Side Effects of Xapavir 50mg Tablet Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Allergic reactions (swelling, high temperature) Infection, inflammation Inflammation of the liver; liver failure Joint pain Common Depression Abnormal dreams, insomnia Itching, rash Being sick Stomach discomfort, pain Headache Diarrhea Fatigue

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HIV/AIDS

INTRODUCTION ABOUT VALCYTE 450MG TABLET VALCYTE 450MG TABLET contains Valganciclovir which belongs to the group of medicines called Antiviral agents. It is used in adults (with acquired immunodeficiency syndrome) to manage cytomegalovirus (CMV) infection of the retina of the eye which generally cause vision problems and blindness. VALCYTE 450MG TABLET is also used in adults and children to manage cytomegalovirus (CMV) infection who are not infected with CMV or who had received an organ transplant from someone who earlier had CMV infection. VALCYTE 450MG TABLET is not recommended for use in patients allergic (hypersensitive) to Valganciclovir, and/or Ganciclovir. Before taking VALCYTE 450MG TABLET, inform your doctor if are undergoing radiotherapy/hemodialysis, and/or suffer from low red blood cell, white blood cell or platelets, kidney/liver problems. VALCYTE 450MG TABLET is not recommended for use in pregnant women unless it is clearly necessary since it may cause harm to the unborn baby. It is also not recommended for use in breastfeeding women. VALCYTE 450MG TABLET should be used with caution in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 65 years and above) after consulting the doctor. The most common side effects of taking VALCYTE 450MG TABLET are oral thrush (fungal infection), headache, shortness of breath, abdominal pain, loss of appetite, nausea, vomiting, and/or diarrhea. Consult your doctor if any of these symptoms worsens. USES OF VALCYTE 450MG TABLET Manage cytomegalovirus (CMV) infection of the retina of the eye in adult patients with acquired immunodeficiency syndrome (AIDS). Prevents cytomegalovirus (CMV) infection who are not infected with CMV or in patients who had received an organ transplant from someone who earlier had CMV infection HOW VALCYTE 450MG TABLET WORKS VALCYTE 450MG TABLET works by managing the multiplication of virus in human cells by decreasing its growth which results in inhibition of production of new virus thus managing and managing the spread of infection to other parts of the body in affected individuals. DIRECTIONS FOR USE Take VALCYTE 450MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF VALCYTE 450MG TABLET COMMON thrush & oral thrush (fungal infection) upper respiratory tract infection such as sinusitis, tonsillitis headache cough, shortness of breath abdominal pain, loss of appetite, nausea/vomiting, diarrhea, weight loss eczema (skin inflammation) tiredness, fever influenza signs of urine infection such as fever, passing urine more often, and/or pain (while passing urine) skin infection signs of mild allergic reaction such as red, itchy skin feeling depressed, anxious or confused trouble sleeping feeling numb/weak in hands/feet changes in sense of touch, tingling/tickling/pricking/burning sensation altered taste, chills eye inflammation/pain or sight problems ear pain signs of low blood pressure such as feeling dizzy/faint difficulty while swallowing constipation, wind, indigestion, stomach pain, swelling of abdomen mouth ulcers night sweats itching, rash hair loss back pain, muscle/joint pain, muscle spasms feeling dizzy, weak/generally unwell UNCOMMON feeling agitated tremor/shaking deafness irregular heartbeat red itchy welt, dry skin blood in urine chest pain RARE Stop taking VALCYTE 450MG TABLET and contact your doctor if you experience any of the following side effects: signs of allergic reaction (anaphylactic shock) such as raised, itchy skin rash, sudden swelling of throat, face, lips/mouth resulting in difficulty while swallowing/breathing, and/or sudden swelling of the hands, feet/ankles. signs of infection (due to low white blood cell count) such as sore throat, mouth ulcer, and/or fever signs of low red blood cell count such as shortness of breath, tiredness, palpitation, and/or pale skin signs of blood infection (sepsis) such as fever, chills, palpitation, confusion, and/or slurred speech signs of low platelet count such as bleeding/bruising, blood in urine/stools, and/or bleeding from gums severely low blood cell count pancreatitis (inflammation of pancreas) associated with severe stomach pain fits hallucinations abnormal thoughts/feelings, losing contact with reality failure of kidney function HOW TO MANAGE SIDE EFFECTS Constipation Try to eat high-fiber foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise (such as going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate managements for constipation.

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Anti Cancer Medicine

Zoleget 4mg Injection belongs to the class of medicines called 'bisphosphonates' used to treat osteoporosis (weak and brittle bones) caused by menopause or long-term steroid use. Zoleget 4mg Injection also treats Paget’s bone and high calcium levels caused by cancer. Osteoporosis is a bone disease that weakens and thins bones by decreasing bone density, common in post-menopausal women. As the density of bones decreases, they weaken and are more likely to break. Zoleget 4mg Injection contains Zoledronic acid that works by binding to the bone tightly and preventing the removal of calcium by osteoclasts (a type of bone cell that destroys bone tissue). This prevents osteoclasts from breaking down the bone and keeps the bones strong and minimizes the risk of bones breaking. A doctor or nurse will administer Zoleget 4mg Injection. In some cases, you may experience headache, fever, nausea, dizziness, vomiting, back pain, diarrhea, pain in the muscles, joints, or bones, swelling, or pain at the infusion site. Most of these side effects of Zoleget 4mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. If you are allergic to Zoleget 4mg Injection or any other medicines, please tell your doctor. Avoid taking Zoleget 4mg Injection if you are pregnant or breastfeeding and consult a doctor. Zoleget 4mg Injection is not recommended for children below 18 years as the safety and effectiveness were not established. Avoid taking Zoleget 4mg Injection if you have hypocalcemia (low calcium levels in the blood) and severe kidney problems. Drive only if you are alert as Zoleget 4mg Injection may cause dizziness. Zoleget 4mg Injection may cause osteonecrosis of the jaw (ONJ) in some patients. Therefore, if you experience any problems with teeth or mouth such as loose teeth, swelling or pain, non-healing of sores, or discharge, consult your doctor and dentist as these might be signs of osteonecrosis of the jaw.

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Anti Cancer Medicine

Mesna 200mg Injection is used to prevent ifosfamide-induced hemorrhagic cystitis (bleeding in the bladder that may be caused as a side effect due to treatment with a cancer chemotherapy drug called ifosfamide). However, it is not used to reduce the risk of bladder bleeding due to other medical conditions. Mesna 200mg Injection is given under the supervision of a doctor. The dose and duration of the treatment vary based on your need and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Some common side effects of this medicine include nausea, headache, lightheadedness, lethargy, and abdominal pain. It is advised to drink at least 1 liter of fluid daily when you are on treatment with this medicine. You should seek immediate medical attention if you experience signs of severe allergic reactions like rash, itching, breathing difficulty, chest tightness, and swelling of the mouth, face, lips, or tongue while taking this medicine. Regular blood tests are required to check your blood cells along with the kidney, liver, and blood uric acid levels.

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Anti Cancer Medicine

Cort S 100mg Injection belongs to a group of medicines called corticosteroids. It is used to treat a variety of diseases and conditions such as severe allergic reactions, allergic conditions, cancer, and skin and eye disorders. It is used for the treatment of conditions that need a quick response. Cort S 100mg Injection is administered by a healthcare professional. It is usually given to patients who are not able to take the tablet form of the medicine. Taking the medicine can make it harder for your body to fight off infections. Tell your doctor if you have any signs of infection such as a fever or sore throat. Also before taking this medicine, you should let your doctor know all the other medicines you are taking. The most common side effect of this medicine is intense pain and swelling in the joint where the injection was given. This usually gets better after a few days. It may also cause mood changes in some people. If any of these side effects bother you or if you experienced any symptoms which you feel are due to the use of this medicine, let your doctor know.

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General Medicine

Dopacan Injection is a brand of Dopamine Hydrochloride, a potent vasopressor and inotropic agent used in critical care settings to manage various cardiovascular conditions. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dopacan Injection is indicated for: • Shock Management: Including septic shock, cardiogenic shock, and hypovolemic shock. • Acute Heart Failure: To improve cardiac output and perfusion. • Severe Hypotension: Especially in patients unresponsive to volume resuscitation. • Renal Protection: To enhance renal blood flow and urine output in certain critically ill patients. Dopamine works by stimulating dopaminergic and beta-adrenergic receptors, leading to increased heart rate, contractility, and renal perfusion. At higher doses, it also stimulates alpha-adrenergic receptors, causing vasoconstriction and increased blood pressure. ________________________________________ ⚙️ Dosage and Administration Dopacan Injection is administered intravenously, with the dosage tailored to the patient's condition and response: • Low Dose (1–5 mcg/kg/min): Primarily stimulates dopaminergic receptors, increasing renal blood flow and urine output. • Medium Dose (5–15 mcg/kg/min): Stimulates beta-1 adrenergic receptors, enhancing heart rate and contractility. • High Dose (15–50 mcg/kg/min): Stimulates alpha-1 adrenergic receptors, leading to vasoconstriction and increased blood pressure. Continuous monitoring of blood pressure, heart rate, and urine output is essential during administration. ________________________________________ ⚠️ Precautions and Contraindications Before using Dopacan Injection, inform your healthcare provider if you have: • Allergies to dopamine or other components of the injection. • A history of heart rhythm disorders or coronary artery disease. • Pheochromocytoma (a rare tumor of the adrenal glands). • Diabetes, asthma, or sulfite allergies. • Circulatory disorders such as Raynaud's disease or Buerger's disease. • Recent use of monoamine oxidase inhibitors (MAOIs). This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. ________________________________________ 💊 Side Effects Common side effects may include: • Palpitations or increased heart rate. • Nausea and vomiting. • Headache. • Difficulty breathing. • Gangrene (in rare cases, due to excessive vasoconstriction). Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.

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