Celdaz 500 Injection is a chemotherapeutic medicine used in the treatment of skin cancer. Cancer is a condition where the cells grow and reproduce uncontrollably in a specific body part. These cancerous cells can attack and destroy surrounding healthy tissue and organs. Celdaz 500 Injection is used in the treatment of metastatic malignant melanoma. It is a serious condition in which the cancer grows in melanocytes and also spreads to other parts of the body. Celdaz 500 Injection is also used as a second-line therapy in the treatment of Hodgkin’s Disease when used in combination with other approved drugs. Celdaz 500 Injection contains Dacarbazine, which belongs to the class of alkylating agents. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This helps prevent the growth and further spread of cancerous or non-cancerous cells. Celdaz 500 Injection may cause certain side effects, such as nausea, vomiting, headache, dizziness, and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Celdaz 500 Injection is a parenteral preparation. A trained healthcare professional will administer it.

Cytasted 1000 Injection 10 ml is an anticancer medicine used in the treatment of leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. Cytasted 1000 Injection 10 ml is used in the treatment of different types of leukemias, such as acute non-lymphocytic leukemia, acute lymphocytic leukemia, chronic myelocytic leukemia and meningeal leukemia. Cytasted 1000 Injection 10 ml contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for the growth, repair and multiplication of cells. Thus, Cytasted 1000 Injection 10 ml stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells. Cytasted 1000 Injection 10 ml may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dark-coloured urine, stomach pain, hair loss, dizziness, weakness, and pain at the site of injection, prescribed by your doctor. Most of these side effects of Cytasted 1000 Injection 10 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please seek medical help. A trained healthcare professional will administer Cytasted 1000 Injection 10 ml. Hence, do not self-administer.

Introduction to Lastet 100mg Injection Lastet 100mg injection is an anticancer drug with the ingredient Etoposide. It belongs to the medication class known as cytostatic. It is used to treat certain types of cancers such as testicular cancer, small-cell lung cancer, acute myeloid leukemia (blood cancer), tumor in the lymphatic system (Hodgkin’s lymphoma, non-Hodgkin’s lymphoma), and ovarian cancer in adults. Talk to your doctor if you had or currently having radiotherapy or chemotherapy. Report to your doctor if you have any infections or low levels of protein (albumin) in your blood. Lastet 100mg Injection should not be taken if you have recently been vaccinated with yellow fever or any live vaccines. Before starting treatment with this medicine, it is very important to tell your physician if you currently or previously had any medical conditions of kidney problems or liver disorders. Both women and men should use effective birth control during the treatment and at least 6 months after the last dose. In men, it is recommended not to father a child during and up to 6 months after the treatment. So it is advised to get suggestions about fertility concerns from your doctor. Administration of Lastet 100mg injection may cause a reduction in the level of blood cells and increase the risk of developing infections. So, your doctor may perform blood tests regularly to monitor your kidney and liver function. It is unknown whether it is safe to use on a child. Uses of Lastet 100mg Injection Testicular cancer Small-cell lung cancer Acute myeloid leukemia (blood cancer) Hodgkin’s lymphoma and non-Hodgkin’s lymphoma Ovarian cancer Therapeutic Effects of Lastet 100mg Injection Lastet 100mg works by inhibiting the activity of topoisomerase II (essential for cell replication) and DNA synthesis, which will prevent cancer cells from growing and multiplying, ultimately leading to cell death. Interaction of Lastet 100mg Injection with other drugs Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications such as Ciclosporin, Phenytoin, Phenobarbitone, Warfarin, Anthracyclines, Aspirin, and Fosphenytoin may interact with Lastet 100mg and reduce effectiveness by causing undesirable side effects. More Information about Lastet 100mg Injection Keep Lastet 100mg out of sight and reach of children. Store at a controlled room temperature between 15°C to 30°C. Store in the original package Do not refrigerate or freeze. How to consume Lastet 100mg Injection Lastet 100mg injection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administrate. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person. Safety Advices for Lastet 100mg Injection Image Not Available Pregnancy Do not take this Lastet 100mg if you are pregnant because it may cause harm to the unborn baby. Consult your doctor before starting the treatment. Image Not Available Breast Feeding It is unsafe to breastfeed while taking Lastet 100mg because it can cause toxicity to the baby. Please consult your physician for more advice. Image Not Available Lungs Consult your doctor if you experience any lung-related symptoms like; shortness of breath or lung inflammation while taking a Lastet 100mg injection. Image Not Available Liver You need to tell your doctor if you have any liver disorders before taking Lastet 100mg Injection. Your doctor may perform blood tests regularly to monitor your condition. Consult your doctor for more information. Image Not Available Alcohol It is unknown if drinking alcohol while taking a Lastet 100mg injection is safe. Please speak with your physician. Image Not Available Driving Driving while taking a Lastet 100mg injection is unsafe because this medicine can cause tiredness, lightheadedness, or dizziness. Side Effects of Lastet 100mg Injection Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Severe allergic reactions (swelling of tongue, or throat, breathing difficulties, rash, flushing, fast heartbeat) Irregular heartbeat (arrhythmia) Blood disorder Hepatotoxicity (damage to the liver) Acute leukemia Common Nausea, vomiting Loss of appetite Abdominal pain Constipation, diarrhea Changes in skin color Weakness Asthenia (feeling weak) Temporary hair loss High or low blood pressure Dizziness Redness of the skin Sore lips, throat, or mouth ulcers Word of Advice Discuss your fertility problem with the doctor since, in men, it is advised not to father a child during and after the 6 months of treatment. So it is advised to get suggestions about fertility concerns. Avoid planning for the pregnancy.

Cynocan 12 Injection is a brand of Cyanocobalamin (Vitamin B₁₂) used to treat and prevent vitamin B₁₂ deficiency. Cyanocobalamin is a synthetic form of vitamin B₁₂, which is essential for nerve function, red blood cell formation, and DNA synthesis. ________________________________________ 🩺 Medical Uses Cynocan 12 Injection is prescribed for: • Pernicious Anemia: A condition where the body cannot absorb vitamin B₁₂ due to a lack of intrinsic factor. • Vitamin B₁₂ Deficiency: Caused by dietary insufficiency, malabsorption, or certain medical conditions. • Neurological Symptoms: Such as numbness, tingling, or weakness in the limbs. • Fatigue and Weakness: Associated with low vitamin B₁₂ levels. • Megaloblastic Anemia: A blood disorder characterized by the presence of abnormally large red blood cells. ________________________________________ ⚙️ Mechanism of Action Cyanocobalamin is converted in the body to its active forms, methylcobalamin and adenosylcobalamin, which are involved in: • DNA Synthesis: Essential for proper cell division. • Red Blood Cell Formation: Prevents anemia. • Nerve Function: Maintains the health of nerve cells. ________________________________________ 💉 Administration and Dosage Cynocan 12 Injection is administered by a healthcare professional: • Intramuscular (IM) or Subcutaneous (SC) Injection: Typically given in a clinical setting. • Dosage: Varies based on the individual's condition and response to treatment. For specific dosing instructions, consult your healthcare provider. ________________________________________ ⚠️ Side Effects Common side effects may include: • Injection site reactions (pain, redness, swelling) • Headache • Nausea or vomiting • Dizziness • Fatigue Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or swelling in the legs. ________________________________________ ⚠️ Precautions Before using Cynocan 12 Injection, inform your healthcare provider if you have: • Allergies to cyanocobalamin or any other components of the injection. • Leber's disease (a hereditary optic nerve disorder). • Kidney or liver disease. • A history of blood clots or stroke. Cyanocobalamin may interact with certain medications. Inform your doctor about all the medicines you are taking, including over-the-counter drugs and supplements.

Clocivir 500 Injection is an intravenous formulation containing Acyclovir 500 mg, manufactured by American Remedies. It is primarily used to treat severe viral infections caused by herpes viruses. ________________________________________ 🩺 Uses of Clocivir 500 Injection Clocivir 500 Injection is indicated for: • Herpes Simplex Infections in Immunocompromised Patients: Including severe primary or non-primary genital herpes. • Herpes Simplex Encephalitis: A serious brain infection caused by the herpes simplex virus. • Neonatal Herpes Simplex Virus Infection: In newborns. • Varicella-Zoster Infections in Immunocompromised Patients: Such as severe cases of chickenpox or shingles. • Severe Herpes Zoster (Shingles): In immunocompetent patients with very severe acute local or systemic manifestations. ________________________________________ 💊 Mechanism of Action Acyclovir, the active ingredient in Clocivir, is a synthetic purine nucleoside analogue. It exerts its antiviral effects by inhibiting viral DNA synthesis, thereby preventing the replication of herpes viruses. Acyclovir is converted to its active form, Acyclovir Triphosphate, within infected cells, which then interferes with viral DNA polymerase. ________________________________________ ⚠️ Precautions • Administration: Clocivir 500 Injection should be administered by a healthcare professional through slow intravenous infusion over a 1-hour period to minimize the risk of kidney damage. • Hydration: Adequate hydration is essential during treatment to prevent dehydration and kidney damage. • Kidney Function: Use with caution in patients with pre-existing kidney conditions. • Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Clocivir 250 Injection is an intravenous formulation containing Acyclovir 250 mg, manufactured by American Remedies. It is primarily used to treat severe viral infections caused by herpes viruses. ________________________________________ 🩺 Uses of Clocivir 250 Injection Clocivir 250 Injection is indicated for: • Herpes Simplex Virus Infections: Including severe cases in immunocompromised patients. • Genital Herpes: Especially primary or non-primary severe cases. • Herpes Zoster (Shingles): In immunocompetent patients with severe manifestations. • Chickenpox (Varicella Zoster Virus Infection): Particularly in immunocompromised individuals. • Herpes Simplex Encephalitis: A severe brain infection caused by the herpes simplex virus. ________________________________________ 💊 Mechanism of Action Acyclovir, the active ingredient in Clocivir, is a synthetic purine nucleoside analogue. It exerts its antiviral effects by inhibiting viral DNA synthesis, thereby preventing the replication of herpes viruses. Acyclovir is converted to its active form, Acyclovir Triphosphate, within infected cells, which then interferes with viral DNA polymerase . ________________________________________ ⚠️ Precautions • Administration: Clocivir 250 Injection should be administered by a healthcare professional through slow intravenous infusion over a 1-hour period to minimize the risk of kidney damage . • Hydration: Adequate hydration is essential during treatment to prevent dehydration and kidney damage. • Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to conceive, or breastfeeding. • Drug Interactions: Inform your healthcare provider about all other medications you are taking to avoid potential interactions.

Essential Oto® is a physiological cleanser specifically designed for the regular hygiene of dogs, cats or rabbits’ ears(Excess earwax, Earwax plugs, Bad odors). Based on active ingredients of 100% natural origin, it helps eliminate excessive earwax and debris while deodorizing ear canals. It also has a hydrating and soothing action. Thanks to its alcohol-free formula and its mild ceruminolytic agents, Essential Oto® is perfectly adapted to the maintenance of healthy ears even the most sensitive. Its use is facilitated thanks to a twist-off service cap allowing a single-handed opening. Its transparent bottle enables to check the integrity of the formula throughout the product’s lifespan.

Essential 6® spot-on is the 1st patented dermo-care spot-on that provides a simple and efficient solution to skin disorders of dogs, cats and small mammals (rabbits, ferrets, guinea pigs, hamsters, rats, mice…)Essential 6® spot-on combines 6 actions and helps: 1. Hydrate the skin and reinforce the skin barrier function 2. Enhance coat shine 3. Diminish hair loss (outside seasonal molt) and support hair regrowth 4. Reduce flaking 5. Deodorize while respecting the animal’s sense of smell 6. Protect thanks to its antioxydant effect. With a simple 2 second application per week, Essential 6® spot-on helps space out shampoo frequency and can substitute the daily oral in-take of essential fatty acids (Omega 6 and 3).

Essential 6® Sebo Shampoo is a sebo-regulating shampoo that provides an efficient solution to skin disorders. Thanks to its soap-free formula rich in in active ingredients of 100% natural origin, Essential 6® Sebo Shampoo gently cleanses, eliminates dandruff and bad odors, improves coat shine and rebalances the skin. Moreover, it moisturizes and helps reinforce the skin barrier.