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'combination antibiotic formulation'

Items tagged with 'combination antibiotic formulation'

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Eye Care

Tobi-F (Tobramycin Sulphate and Fluorometholone) Ophthalmic Solution is a prescription eye drop that combines an antibiotic and a corticosteroid to treat specific eye conditions. ________________________________________ ✅ Primary Uses Tobi-F is primarily used to manage inflammatory eye conditions where a steroid is indicated and where there is a risk of or existing superficial bacterial infection. The combination of tobramycin and fluorometholone addresses both the infection and the inflammation. ________________________________________ 💊 Dosage and Administration • Standard Dosage: Instill 1–2 drops into the affected eye(s) every 4–6 hours, or as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Contraindications and Cautions • Contraindications: o Hypersensitivity to tobramycin, fluorometholone, or any component of the formulation. o Active viral infections of the eye, such as herpes simplex keratitis. • Untreated fungal or mycobacterial infections of the eye. • Cautions: o Use with caution in patients with a history of glaucoma, as corticosteroids can increase intraocular pressure. o Prolonged use may lead to cataract formation or secondary ocular infections. o Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.

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Eye Care

Tobi (Tobramycin Ophthalmic Solution) is a prescription antibiotic eye drop used to treat bacterial infections of the eye. It contains 0.3% tobramycin, a broad-spectrum aminoglycoside antibiotic effective against various gram-positive and gram-negative bacteria. ________________________________________ ✅ Primary Uses • Bacterial Conjunctivitis: Infection of the conjunctiva (the membrane covering the white part of the eye and the inner surface of the eyelids). • Blepharitis: Inflammation of the eyelid margins, often associated with bacterial infection. • Keratitis: Infection of the cornea. • Post-surgical Infections: Prophylactic treatment or management of infections following eye surgeries. Tobramycin ophthalmic solution is typically used alone or in combination with other medications, depending on the severity and type of infection . ________________________________________ 💊 Dosage and Administration • Standard Dosage: Instill 1–2 drops into the affected eye every 4 hours during the day. • Severe Infections: In some cases, the dosage may be increased to 2 drops every hour, as directed by a healthcare provider . • Application Tips: o Wash hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If wearing contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: • Hypersensitivity to tobramycin or any component of the formulation . • Cautions: o Use with caution in pregnant or breastfeeding women; consult a healthcare provider before use . o Prolonged use may lead to the development of resistant bacteria. o Should not be used in children without medical supervision. ________________________________________

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General Medicine

Pipracan 4.5 Injection is a combination antibiotic medication containing Piperacillin (4 g) and Tazobactam (0.5 g). This formulation is used to treat a wide range of serious bacterial infections that may not respond to other antibiotics. ________________________________________ 🔹 Common Uses Pipracan 4.5 Injection is prescribed for: • Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) • Urinary tract infections (UTIs) • Intra-abdominal infections (e.g., peritonitis) • Skin and soft tissue infections, including diabetic foot infections • Gynecological infections, such as uterine infections • Bone and joint infections • Bloodstream infections (bacteremia) It is also used for prophylactic treatment in surgical procedures to prevent infections. ________________________________________ 🔹 How It Works • Piperacillin is a broad-spectrum penicillin antibiotic that inhibits bacterial cell wall synthesis, leading to bacterial cell death. • Tazobactam is a beta-lactamase inhibitor that protects piperacillin from degradation by beta-lactamase enzymes produced by certain bacteria, thereby enhancing its efficacy. This combination allows Pipracan 4.5 to target a wide array of bacteria, including those resistant to other antibiotics. ________________________________________ 🔹 Administration Pipracan 4.5 Injection is administered intravenously by a healthcare professional. The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient's medical condition. Self-administration is not recommended. ________________________________________ 🔹 Side Effects Common side effects may include: • Nausea or vomiting • Diarrhea • Rash or itching • Pain, redness, or swelling at the injection site Serious side effects are rare but can include allergic reactions, liver enzyme abnormalities, or blood disorders. Seek immediate medical attention if you experience symptoms like difficulty breathing, swelling of the face or throat, or unusual bruising or bleeding. ________________________________________ 🔹 Precautions Before using Pipracan 4.5 Injection, inform your doctor if you have: Allergies to penicillins or beta-lactam antibiotics • Kidney or liver disease • A history of gastrointestinal diseases, such as colitis • Bleeding disorders • Undergoing dialysisUse during pregnancy and breastfeeding should be discussed with your healthcare provider. The medication should only be used if the potential benefits justify the potential risks.

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General Medicine

Ceforzone SB 1.5 Injection is a combination antibiotic formulation containing Cefoperazone (1000 mg) and Sulbactam (500 mg). Manufactured by American Remedies, it is primarily used to treat a wide range of bacterial infections. ________________________________________ 🩺 Uses of Ceforzone SB 1.5 Injection Ceforzone SB 1.5 Injection is indicated for the treatment of various bacterial infections, including: • Respiratory Tract Infections: Such as pneumonia and bronchitis. • Urinary Tract Infections: Including cystitis and pyelonephritis. • Intra-abdominal Infections: Such as peritonitis and abscesses. • Skin and Soft Tissue Infections: Including cellulitis and wound infections. • Bone and Joint Infections: Such as osteomyelitis and septic arthritis. • Meningitis: Infection of the membranes covering the brain and spinal cord. • Pelvic Inflammatory Disease: Infection of the female reproductive organs. • Gonorrhea: A sexually transmitted infection. Septicemia: Bloodstream infection. Surgical Prophylaxis: To prevent infections associated with major surgeries. ________________________________________ 💊 Mechanism of Action • Cefoperazone: A third-generation cephalosporin antibiotic that inhibits the synthesis of the bacterial cell wall, leading to cell lysis and death. Sulbactam: A beta-lactamase inhibitor that protects cefoperazone from enzymatic degradation by bacterial beta-lactamases, thereby enhancing its antibacterial activity. ________________________________________ ⚠️ Precautions • Allergy: Inform your healthcare provider if you have a history of allergic reactions to penicillins, cephalosporins, or beta-lactam antibiotics. • Liver or Kidney Impairment: Use with caution in patients with liver or kidney dysfunction. Dosage adjustments may be necessary. • Pregnancy and Breastfeeding: Consult your doctor before use during pregnancy or breastfeeding. • Drug Interactions: Inform your healthcare provider about all other medications you are taking to avoid potential interactions.

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General Medicine

Clavcan 1.2 Injection is a combination antibiotic formulation containing Amoxicillin (1000 mg) and Clavulanic Acid (200 mg). It is manufactured by American Remedies and is primarily used to treat a wide range of bacterial infections. ________________________________________ 🩺 Uses of Clavcan 1.2 Injection Clavcan 1.2 Injection is indicated for the treatment of various bacterial infections, including: • Respiratory Tract Infections: Such as pneumonia and acute exacerbations of chronic bronchitis. Urinary Tract Infections: Including cystitis, urethritis, and pyelonephritis. Skin and Soft Tissue Infections: Such as cellulitis, boils, and wound infections. Bone and Joint Infections: Including osteomyelitis. • Middle Ear Infections: Such as otitis media. Tonsillitis and Sinusitis: Infections of the tonsils and sinuses. Intra-abdominal Infections: Including peritonitis and abscesses. • Dental Infections: Such as dental abscesses. • Genital Infections in Females: Including pelvic inflammatory disease. • Prophylaxis: To prevent infections associated with major surgeries of the heart, joints, kidney, head and neck, stomach, biliary tract, intestine, and pelvic region. ________________________________________ 💊 Mechanism of Action • Amoxicillin: A penicillin-type antibiotic that inhibits the synthesis of bacterial cell walls, leading to bacterial cell death. • Clavulanic Acid: A beta-lactamase inhibitor that prevents bacterial enzymes from breaking down amoxicillin, thereby enhancing its effectiveness against resistant bacteria. ________________________________________ ⚠️ Precautions • Allergy: Inform your doctor if you have a history of allergic reactions to penicillin or other antibiotics. • Liver or Kidney Disease: Use with caution in patients with liver or kidney impairments. • Pregnancy and Breastfeeding: Consult your doctor before use during pregnancy or breastfeeding. • Drug Interactions: Inform your healthcare provider about all other medications you are taking to avoid potential interactions.

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General Medicine

Clarican 500 Injection is an intravenous formulation of Clarithromycin, a semi-synthetic macrolide antibiotic manufactured by American Remedies. It is primarily used to treat severe bacterial infections when oral antibiotics are not suitable or effective. ________________________________________ 🩺 Uses of Clarican 500 Injection Clarican 500 Injection is indicated for the treatment of various bacterial infections, including: • Lower Respiratory Tract Infections: Such as pneumonia and bronchitis. Upper Respiratory Tract Infections: Including sinusitis and pharyngitis. Skin and Soft Tissue Infections: Such as cellulitis and erysipelas. Mycobacterial Infections: Like Mycobacterium avium complex (MAC) infections, particularly in immunocompromised individuals. Helicobacter pylori Eradication: In combination with other medications, to treat peptic ulcers caused by H. pylori. ________________________________________ 💊 Mechanism of Action Clarithromycin works by binding to the 50S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis and thereby preventing bacterial growth. ________________________________________ ⚠️ Precautions Before administering Clarican 500 Injection, inform your healthcare provider if you: • Have a history of liver or kidney disease. • Are pregnant or breastfeeding. • Are taking other medications, especially those metabolized by the liver. This medication should be administered under the supervision of a healthcare professional.

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Eye Care

Tropind Plus is a combination ophthalmic solution containing Tropicamide 0.8% and Phenylephrine 5%. This formulation is primarily used for both diagnostic and therapeutic purposes in ophthalmology. 🩺 Primary Uses of Tropind Plus 1. Pupillary Dilation (Mydriasis): The combination of Tropicamide and Phenylephrine effectively dilates the pupil, allowing eye care professionals to conduct thorough examinations of the retina, optic nerve, and other internal structures. 2. Cycloplegia: Tropicamide paralyzes the ciliary muscle, preventing accommodation (focusing), which is useful in refractive error assessments. 3. Uveitis Management: In cases of uveitis, Tropind Plus helps alleviate pain and prevents further spasms of the eye muscles. 4. Preoperative Preparation: Before surgeries like cataract extraction or retinal procedures, dilating the pupil is essential for clear visualization of the posterior segment. 5. Retinal Imaging: Facilitates procedures such as fundus photography and optical coherence tomography (OCT) by ensuring adequate pupil dilation. ⚙️ How It Works • Tropicamide is a parasympatholytic agent that inhibits the contraction of the circular muscle and paralyzes the ciliary muscle, leading to pupil dilation and cycloplegia. Phenylephrine is a sympathomimetic drug that causes contraction of the radial muscle of the iris, contributing to pupil dilation. Together, these agents produce rapid and effective dilation of the pupil, facilitating detailed eye examinations and procedures. ⚠️ Side Effects Common side effects may include: • Eye pain or stinging • Blurred vision • Sensitivity to light (photophobia) • Allergic reactions These effects are typically temporary and resolve shortly after the examination. 🧪 Safety and Precautions • Driving and Operating Machinery: Avoid activities that require clear vision, such as driving, immediately after application, as the solution can cause temporary blurred vision. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or while breastfeeding, as safety data may be limited. • Drug Interactions: Be cautious when using Tropind Plus with certain medications, especially monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants, as interactions may occur.

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Eye Care

Tobi-D (Tobramycin with Dexamethasone) Eye Drops is a prescription ophthalmic solution combining an antibiotic and a corticosteroid to treat specific bacterial eye infections accompanied by inflammation. ________________________________________ ✅ Primary Uses Tobi-D is primarily used for: • Bacterial Conjunctivitis: Infection of the conjunctiva (the membrane covering the white part of the eye and the inner surface of the eyelids). • Keratitis: Infection of the cornea. • Post-surgical Infections: Prophylactic treatment or management of infections following eye surgeries. It addresses both the infection and the inflammation associated with these conditions. ________________________________________ 💊 Dosage and Administration • Standard Dosage: Instill 1–2 drops into the affected eye(s) every 4–6 hours, or as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Contraindications and Cautions • Contraindications: o Hypersensitivity to tobramycin, dexamethasone, or any component of the formulation. o Active viral infections of the eye, such as herpes simplex keratitis. o Untreated fungal or mycobacterial infections of the eye. • Cautions: o Use with caution in patients with a history of glaucoma, as corticosteroids can increase intraocular pressure. o Prolonged use may lead to cataract formation or secondary ocular infections. o Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. ________________________________________ 🧪 Mechanism of Action • Tobramycin: An aminoglycoside antibiotic that inhibits bacterial protein synthesis, leading to bacterial cell death. • Dexamethasone: A corticosteroid that reduces inflammation by inhibiting the release of inflammatory mediators. Together, these components address both the infection and the inflammation associated with certain eye conditions.

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