Geftinat 250 mg Tablets Generic Name: Gefitinib Manufacturer: Natco Pharma Ltd Form: Oral tablets Strength: 250 mg Indication / Use: Geftinat (Gefitinib) is indicated for: The treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC). Particularly effective in patients whose tumors have epidermal growth factor receptor (EGFR) mutations. Mechanism of Action: Gefitinib is an EGFR tyrosine kinase inhibitor (TKI). It works by blocking signals involved in the growth and spread of cancer cells. Dosage: Typically one 250 mg tablet once daily, with or without food. Dosage adjustments may be necessary based on individual tolerance and physician guidance. Common Side Effects: Diarrhea Rash Acne Nausea Fatigue Loss of appetite Dry skin Precautions: Liver function monitoring is advised. Not recommended during pregnancy or breastfeeding. Patients with interstitial lung disease should use with caution. Should not be used in patients allergic to Gefitinib or any of its components. Storage: Store in a cool, dry place below 30°C. Keep out of reach of children.

Lignocan-ADR Injection is a local anesthetic. It is used to numb tissues in a specific area. It decreases the pain sensation by blocking the pain signals from the nerves to the brain. Lignocan-ADR Injection is given by a doctor or a nurse and should not be self-administered. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. This medicine may cause few common side effects such as pale colored skin, burning sensation, stinging sensation, erythema, itching. If you experience any such side effects that does not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects. In general, you should try to use the smallest amount necessary to control your symptoms.

Duron Injection Salt: Amiodarone (150mg) Description Duron 150mg Injection is used to treat various types of serious irregular heartbeat (arrhythmia) such as fibrillation and tachycardia (increased heart rate). It is an anti-arrhythmic type of medicine which rapidly restores your heart to a steady and regular rhythm. Duron 150mg Injection is used to treat various types of serious irregular heartbeat (arrhythmia) such as fibrillation and tachycardia (increased heart rate). It is an anti-arrhythmic type of medicine which rapidly restores your heart to a steady and regular rhythm. Duron 150mg Injection is given by a slow drip (infusion) into a vein under the supervision of a doctor. Continuous monitoring of blood pressure and heart rate may be needed while this medicine is administered. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of the injection. If you stop taking this medicine, you may get dangerous uneven heartbeats, which can be life-threatening. The most common side effects of this medicine include decreased blood pressure (hypotension), decreased heart rate (bradycardia), blurred vision, and application site reaction(pain, itching, and skin redness). This medicine can also cause problems with your liver, lungs, nerves, and thyroid gland. Ask your doctor what signs to look out for and report any symptoms you have. This medicine takes a long time to get cleared from the body. You may continue to have side effects after you stop using it. Ask your doctor about ways to prevent or reduce them Benefits 1. In Arrhythmia: Duron 150mg Injection belongs to a group of medicines called anti-arrhythmics. It works by blocking abnormal electrical signals in the heart. This helps control the uneven beating of your heart and helps it to beat normally. It is normally only given by injection in a hospital when a fast response is needed or when tablets have not worked or cannot be given. This medicine thus prevents serious health problems that can sometimes be fatal and reduces your risk of death. Side Effects Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Common side effects of Duron: - Decreased blood pressure - Slow heart rate - Blurred vision - Application site reactions (burning, irritation, itching and redness)

Solet 40mg Tablet Marketer Samarth Life Sciences Pvt Ltd SALT COMPOSITION Sotalol (40mg) Storage Store below 30°C Marketer Samarth Life Sciences Pvt Ltd SALT COMPOSITION Sotalol (40mg) Uses of Solet Tablet Arrhythmia Product introduction Solet Tablet is used to treat various types of serious irregular heartbeat (arrhythmia) such as fibrillation and tachycardia. It is an anti-arrhythmic type of medicine and rapidly restores your heart to a steady and regular rhythm. Solet Tablet should be taken as advised by your doctor. It may be taken with or without food. Continuous monitoring of blood pressure and heart rate may be needed while taking this medicine. It is important that you keep taking it until your doctor decides it is safe to stop it. If you stop taking this medicine, you may get dangerous uneven heartbeats, which can be life-threatening. The most common side effects of this medicine include nausea, vomiting, taste change, slow heart rate, diarrhea, and sleep difficulty. This medicine can also cause problems with your liver, lungs, nerves and thyroid gland. Ask your doctor what signs to look out for and report any symptoms you have. It takes a long time to clear from the body. You may continue to have side effects after you stop using it. Ask your doctor about ways to prevent or reduce them. Before getting this medicine, you should let your doctor know if you have low blood pressure, drink a lot of alcohol or have liver, heart or thyroid problems. You should also inform your doctor about all other medicines that you are taking as many can seriously affect or be affected by this medicine. Some medicines like certain antibiotics and medicines for depression and mental illness should be avoided with this medicine. Pregnant or breastfeeding women should consult their doctor before taking this medicine. Your doctor will carry out regular tests to check your liver and thyroid gland. You may also be advised other blood tests, x-rays, and eye tests both before and during treatment. Side effects of Solet Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Solet Fatigue Arrhythmia (irregular heartbeats) Dizziness Slow heart rate Breathlessness Weakness Sleep disorder How to use Solet Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Solet Tablet may be taken with or without food, but it is better to take it at a fixed time. Avoid Solet Tablet with dairy products such as milk, cheese, curd, butter, paneer and ice cream. How Solet Tablet works Solet Tablet is an anti-arrhythmic medication. It regulates heart beat by blocking abnormal electrical signals in the heart. Safety advice warnings Alcohol UNSAFE It is unsafe to consume alcohol with Solet Tablet. warnings Pregnancy CONSULT YOUR DOCTOR Solet Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Solet Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. warnings Driving UNSAFE Solet Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. warnings Kidney CAUTION Solet Tablet should be used with caution in patients with kidney disease. Dose adjustment of Solet Tablet may be needed. Please consult your doctor. warnings Liver SAFE IF PRESCRIBED Solet Tablet is safe to use in patients with liver disease. No dose adjustment of Solet Tablet is recommended.

Adenoz 6mg Injection Marketer Celon Laboratories Ltd SALT COMPOSITION Adenosine (6mg) Storage Store below 25°C Product introduction Adenoz 6mg Injection is an anti-arrhythmic medicine used to treat life-threatening arrhythmia (abnormal heart rhythm). It restores normal heart rhythm by blocking abnormal electrical signals in the heart. Adenoz 6mg Injection is also used to carry out diagnostic stress tests of the heart. It is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your blood pressure, heart rate, and ECG until you become stable. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. Common side effects of this medicine include flushing (sense of warmth in the face, ears, neck, and trunk), headache, chest pain, dizziness, and nausea. Consult your doctor if these effects bother you. This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any kidney or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly. Uses of Adenoz Injection Arrhythmia Side effects of Adenoz Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Adenoz Flushing (sense of warmth in the face, ears, neck and trunk) Dizziness Lightheadedness Nausea Headache Numbness Chest pain How to use Adenoz Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Adenoz Injection works Adenoz 6mg Injection is an anti-arrhythmic medication. It regulates heart beat by blocking abnormal electrical signals in the heart. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Adenoz 6mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Adenoz 6mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding SAFE IF PRESCRIBED Adenoz 6mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. warnings Driving NOT RELEVANT Not relevant, as Adenoz 6mg Injection is intended for use in hospitalised patients. warnings Kidney SAFE IF PRESCRIBED Adenoz 6mg Injection is safe to use in patients with kidney disease. No dose adjustment of Adenoz 6mg Injection is recommended. warnings Liver SAFE IF PRESCRIBED Adenoz 6mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Adenoz 6mg Injection may not be needed in these patients. Please consult your doctor.

FZ-3 Eye-Ear Drops containing Fluconazole are primarily used to treat fungal infections of the eyes and ears. Fluconazole is an antifungal medication that works by inhibiting the growth of fungi. 🔹 Primary Uses Fungal Eye Infections (Ophthalmic Fungal Infections) Fluconazole in eye drop form is used to treat fungal infections of the eye, such as fungal keratitis or endophthalmitis, which can cause inflammation, pain, and potentially lead to vision loss if left untreated. Fungal Ear Infections (Otomycosis) FZ-3 can be used for treating fungal ear infections, also known as otomycosis, which is often caused by fungi like Aspergillus or Candida. Symptoms include itching, pain, and discharge from the ear canal. 🔹 How It Works Fluconazole is an antifungal agent that works by inhibiting the fungal enzyme lanosterol 14α-demethylase, which is involved in the synthesis of ergosterol, an essential component of the fungal cell membrane. By blocking this enzyme, fluconazole disrupts the fungal cell membrane, leading to fungal cell death or inhibition of growth. ⚠️ Common Side Effects Eye: Mild eye irritation or burning sensation upon application Blurred vision (temporary) Redness or stinging in the eyes Ear: Mild ear irritation Ear itching or discomfort after application Temporary hearing changes (rare) If any of these side effects persist or worsen, consult your healthcare provider. 🔹 Usage Tips Dosage: Typically, 1–2 drops are applied to the affected eye or ear 2–3 times daily, as prescribed by your doctor. Application Instructions: Wash your hands thoroughly before applying the drops. For the eyes: Tilt your head back and gently pull down the lower eyelid to form a pocket. Instill the prescribed number of drops and gently close your eye for a few seconds. For the ears: Tilt your head to one side, apply the drops into the ear canal, and gently massage the ear to help the drops penetrate. If you are using other medications for the eyes or ears, wait about 5 minutes between applying each medication. Contact Lenses: If you wear contact lenses, remove them before applying the drops to avoid any contamination. You can reinsert your lenses after 15 minutes. 🔹 Precautions Allergies: If you have a known allergy to fluconazole or other azole antifungals, do not use the drops. Pregnancy and Breastfeeding: Fluconazole should be used with caution in pregnancy, particularly during the first trimester. Always consult your doctor if you are pregnant or breastfeeding. Underlying Conditions: Inform your healthcare provider if you have any liver or kidney diseases, as these conditions may affect how the medication works in your body. Systemic Absorption: Although FZ-3 is used topically, there is a possibility of systemic absorption. Monitor for any systemic side effects, especially with prolonged use.

Dorzopar Eye Drops containing Dorzolamide 2% are primarily used to lower intraocular pressure (IOP) in individuals with glaucoma or ocular hypertension (high eye pressure). Here's a detailed breakdown of its uses: 🔹 Primary Uses Open-Angle Glaucoma Dorzolamide is a carbonic anhydrase inhibitor that helps reduce the production of aqueous humor (the fluid inside the eye). By decreasing the amount of fluid produced, it lowers the intraocular pressure (IOP), which is important in treating open-angle glaucoma. Glaucoma is a condition where high eye pressure can damage the optic nerve and lead to vision loss. Ocular Hypertension Dorzopar is also used for the treatment of ocular hypertension, a condition in which the eye pressure is elevated but glaucoma has not yet developed. Lowering eye pressure helps prevent the progression to glaucoma. 🔹 How It Works Dorzolamide works by inhibiting the carbonic anhydrase enzyme in the eye. This enzyme is involved in the production of aqueous humor. By blocking this enzyme, Dorzolamide reduces the amount of fluid produced inside the eye, which in turn lowers the eye pressure. ⚠️ Common Side Effects Eye irritation, burning, or stinging upon application Blurred vision (temporary) Redness in the eyes or foreign body sensation Dry eyes or increased tear production Headaches or dizziness (in some cases) Taste disturbance (a bitter taste in the mouth) 🔹 Usage Tips Dosage: Typically, 1 drop in each affected eye, twice daily (morning and evening), or as prescribed by your healthcare provider. Application Instructions: Wash your hands thoroughly before applying the drops. Tilt your head back slightly and pull down your lower eyelid to form a small pocket. Place one drop in the pocket without touching the dropper tip to your eye. Gently close your eye and blink a few times to help spread the medication. If using other eye medications, wait 5–10 minutes between applications. Contact Lenses: Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them. 🔹 Precautions Kidney or Liver Problems: Since Dorzolamide is metabolized in the body, it should be used with caution in individuals with kidney or liver issues. Pregnancy and Breastfeeding: Consult your doctor before using this medication if you are pregnant or breastfeeding, as the safety of Dorzolamide during pregnancy or while breastfeeding has not been fully established. Eye Infections: Be cautious if you have an eye infection, as Dorzolamide may not be suitable for some active infections. Systemic Effects: While Dorzolamide is generally applied locally to the eye, some systemic absorption may occur, leading to side effects like metabolic acidosis (rare). It should be used cautiously in patients with a history of diabetes, kidney disease, or respiratory problems.

Marketer BDR Pharmaceuticals Internationals Pvt SALT COMPOSITION Sorafenib (200mg) Storage Store below 30°C Uses of Livonibe Tablet Pancreatic cancer Small cell lung cancer Liver cancer Kidney cancer Thyroid cancer Blood cancer (Chronic myeloid leukaemia) Gastrointestinal stromal tumour Cancer of colon and rectum Non-small cell lung cancer Soft tissue sarcoma Chronic idiopathic myelofibrosis Breast cancer Product introduction Livonibe 200mg Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer. Livonibe 200mg Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Fatigue, nausea, loss of appetite, hair loss and diarrhea are some common side effects of this medicine. It might cause high blood pressure, so the doctor may ask you for a regular check-up of blood pressure. You must inform your doctor if you notice severe skin reaction such as skin rash, or any pain, swelling, and redness of your hands and feet. Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or high blood pressure. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Side effects of Livonibe Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Livonibe Fatigue Nausea Loss of appetite Diarrhea Abdominal pain Hair loss Weight loss Rash Painful blisters on hands and feet How to use Livonibe Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Livonibe 200mg Tablet is to be taken empty stomach. How Livonibe Tablet works Livonibe 200mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Livonibe 200mg Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Livonibe 200mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Livonibe 200mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving SAFE Livonibe 200mg Tablet does not usually affect your ability to drive. warnings Kidney SAFE IF PRESCRIBED Livonibe 200mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Livonibe 200mg Tablet is recommended. Regular monitoring of blood tests may be advised while you are taking this medicine. warnings Liver CAUTION Livonibe 200mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Livonibe 200mg Tablet may be needed. Please consult your doctor.

Marketer Khandelwal Laboratories Pvt Ltd SALT COMPOSITION Methotrexate (50mg) Storage Store below 30°C Uses of Plastomet Injection Treatment of Cancer Product introduction Plastomet 50 Injection is a medicine used for treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It may be used with other medicines as part of combination therapy. Plastomet 50 Injection is given under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage. The most common side effects of this medicine include nausea, vomiting, loss of appetite, abdominal pain, tiredness, mouth sores, and decreased white blood cells. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is a very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor will advise you regular blood tests to check for these. Before taking it, tell your doctor if have stomach, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, X-rays, and physical examinations both before and during treatment with this medicine. Benefits of Plastomet Injection In Treatment of Cancer Plastomet 50 Injection belongs to a group of medicines called antimetabolites and is referred to as a cytotoxic. It works by slowing the growth of cancer cells in the body. It is used to treat a wide range of cancers such as acute leukemias, non-Hodgkin’s lymphoma, and solid tumors found in breast, lung, bladder, head and neck as well as cervical, ovarian and testicular cancer. It may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated. Side effects of Plastomet Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Plastomet Abdominal pain Indigestion Loss of appetite Nausea Vomiting Tiredness Mouth sore Decreased white blood cell count How to use Plastomet Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Plastomet Injection works Plastomet 50 Injection is an anti-cancer medication. It works by blocking an enzyme (dihydrofolate reductase) involved in DNA synthesis in cancer cells. This slows the growth of cancer cells and eventually kills them. Safety advice warnings Alcohol CAUTION Caution is advised when consuming alcohol with Plastomet 50 Injection. Please consult your doctor. warnings Pregnancy UNSAFE Plastomet 50 Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby. warnings Breast feeding UNSAFE Plastomet 50 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Plastomet 50 Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. warnings Kidney CAUTION Plastomet 50 Injection should be used with caution in patients with kidney disease. Dose adjustment of Plastomet 50 Injection may be needed. Please consult your doctor. Regular monitoring of kidney function test is advised while you are taking this medicine. warnings Liver CAUTION Plastomet 50 Injection should be used with caution in patients with liver disease. Dose adjustment of Plastomet 50 Injection may be needed. Please consult your doctor. Use of Plastomet 50 Injection is not recommended in patients with severe liver disease.