Tamofar (Tamoxifen 20mg) Tablets: Verified Pharmaceutical Exporter from India | Bulk Supplier for USA, UK, Australia, Thailand, Singapore & Jamaica
Description
Product Profile: Tamofar 20mg (Tamoxifen Citrate Tablets)
Tamofar 20mg contains Tamoxifen, a Selective Estrogen Receptor Modulator (SERM). It is a foundational medication in the treatment and prevention of hormone receptor-positive breast cancer, acting as a competitive antagonist of estrogen receptors in breast tissue.
1. Clinical Indications & Usage
Breast Cancer Treatment: Indicated for the adjuvant treatment of hormone receptor-positive breast cancer in women (both pre- and postmenopausal) to reduce the risk of recurrence. It is also used in the treatment of metastatic breast cancer.
Breast Cancer Prevention: Prescribed to reduce the risk of invasive breast cancer in women at high risk.
Ductal Carcinoma in Situ (DCIS): Used to reduce the risk of invasive breast cancer following surgery and radiation for DCIS.
2. Mechanism of Action
Tamoxifen functions through a tissue-specific modulation of estrogen receptors:
Antiestrogenic Effect (Breast): By binding to estrogen receptors in the breast, it prevents estrogen from stimulating the growth of cancer cells, thereby effectively inhibiting tumor proliferation in ER-positive cases.
Estrogenic Effect (Other Tissues): In other tissues, such as the endometrium and bone, Tamoxifen can exhibit estrogen-like (agonist) effects, which necessitates clinical monitoring for specific long-term health markers.
3. Administration and Dosing
Regimen: The standard adult dose is typically 20mg per day.
Duration: Treatment is often long-term, frequently spanning 5 to 10 years, as directed by an oncologist.
Administration: Tablets should be taken orally with water, generally at the same time each day, with or without food.
⚠️ Safety, Side Effects, and Monitoring
Contraindications: Do not use if there is a history of deep vein thrombosis (DVT) or pulmonary embolism (PE), if the patient is currently on anticoagulant therapy, or if the patient is pregnant.
Critical Warnings:
Endometrial Risks: Because of its potential agonist effects on the uterus, long-term use can increase the risk of endometrial cancer. Patients should report any abnormal vaginal bleeding immediately.
Thromboembolic Risk: There is an increased risk of stroke, DVT, and PE, particularly in patients with existing risk factors.
Common Side Effects: Hot flashes, vaginal discharge or bleeding, mood swings, nausea, fatigue, and leg cramps.
📦 Storage, Stability & Commercial Packaging
Storage: Store at controlled room temperature (20°C to 25°C / 68°F to 77°F).
Protection: Keep in original blister packaging to protect from light and moisture.
Security: Keep securely out of reach of children and others to prevent accidental ingestion.
PRESCRIPTION MEDICINE IS: YES.
Disclaimer: This profile is compiled strictly for international wholesale procurement and commercial educational research. Tamofar is a specialized prescription medication and must be utilized strictly under the supervision of a licensed oncologist or physician. All import and usage must adhere to the laws and medical regulations of the destination country.
📞 Contact Ernest Impex — Pharmaceutical Exporter from India
[GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.]
🌐 Official Websites:
www.ernestimpex.com
www.oncologymedicinesupplier.com
www.ernestpharmaceuticals.com
www.ernestvision.com
📧 Corporate Email: exports@ernestpharmaceuticals.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 93599 02383
📲 WhatsApp Link: https://wa.me/919359902383
