Ceftriaxone & Sulbactam 1.5g Injection Exporter from India to USA, UK, Australia, Singapore, Thailand, and Jamaica | Premium Antibiotic Combination Supplier | Ernest Impex Global Medicine Exporter
Description
Extensive Product Profile: Understanding Ceftriaxone & Sulbactam for Injection 1.5 g
Ceftriaxone & Sulbactam for Injection 1.5 g is a potent, synergistic antibiotic combination. It pairs Ceftriaxone Sodium, a broad-spectrum, third-generation cephalosporin, with Sulbactam Sodium, a beta-lactamase inhibitor. This formulation is clinically utilized to treat severe bacterial infections by extending the antibacterial spectrum and overcoming resistance mechanisms.
1. Clinical Indications & Usage
Lower Respiratory Tract Infections: Such as severe pneumonia and acute exacerbations of chronic bronchitis.
Urinary Tract Infections (UTIs): Including complicated infections and pyelonephritis.
Intra-abdominal Infections: Management of peritonitis and biliary tract infections.
Skin and Soft Tissue Infections: Treatment of complex wound or structural infections.
Bacteremia and Septicemia: Used for systemic bloodstream infections.
Surgical Prophylaxis: Administered to reduce the risk of post-operative infections.
2. Mechanism of Action
Ceftriaxone: Binds to penicillin-binding proteins (PBPs) in the bacterial cell wall, inhibiting peptidoglycan synthesis, which causes bacterial cell wall lysis and death.
Sulbactam: Functions as a competitive, irreversible beta-lactamase inhibitor. By binding to the beta-lactamase enzymes that would otherwise degrade ceftriaxone, it protects the antibiotic and broadens its spectrum of activity.
3. Administration and Dosing
Route: Administered via intravenous (IV) infusion or deep intramuscular (IM) injection.
Preparation: The sterile powder must be reconstituted with compatible diluents (e.g., Sterile Water for Injection, 0.9% Sodium Chloride) according to clinical requirements.
Dosing: Dosage is strictly determined by the treating physician based on infection severity, patient renal/hepatic function, and age.
⚠️ Safety, Side Effects, and Monitoring
Hypersensitivity: Contraindicated in patients with known severe allergies (anaphylaxis) to cephalosporins, penicillins, or beta-lactamase inhibitors.
Precautions: Avoid mixing with calcium-containing solutions, especially in neonates, due to the risk of precipitate formation.
Precautions: Avoid mixing with calcium-containing solutions, especially in neonates, due to the risk of precipitate formation.
📦 Storage and Handling
Storage: Store the un-reconstituted powder in its original packaging at controlled room temperature (20°C to 25°C), protected from light and moisture.
Stability: Use immediately after reconstitution following standard sterile clinical practices.
PRESCRIPTION MEDICINE IS : YES
Clinical Disclaimer: This profile is compiled for medical professional information and clinical research. Ceftriaxone & Sulbactam for Injection 1.5 g is a prescription-only medication and must be administered strictly under the supervision of a licensed physician or medical facility. Safety in pregnancy has not been established in controlled trials and should only be used if the potential benefit outweighs the risk.
📞 Contact Ernest Impex — Pharmaceutical Exporter from India
[GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.]
🌐 Websites:
www.ernestimpex.com
www.oncologymedicinesupplier.com
www.ernestpharmaceuticals.com
www.ernestvision.com
📧 Email: exports@ernestpharmaceuticals.com
📦 Business Type: Exporter | Supplier | Distributor
📲 WhatsApp: +91 93599 02383
📲 WhatsApp Link: https://wa.me/919359902383
