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'urine output'

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Immunoglobulins

Tacrocord 0.5mg Capsule contains the active substance Tacrolimus. It is an immunosuppressant that belongs to the class of medications called calcineurin inhibitors. This capsule is used along with other medications to prevent organ transplant rejection in people receiving liver, kidney, heart, or other transplants. It is also indicated to control your body’s immune response, enabling it to accept the transplanted organ. Do not take this Tacrocord 0.5mg Capsule if you are allergic to tacrolimus or any of the other ingredients of this medicine. Report your physician if you are allergic to any antibiotic group. Inform your doctor if you have or had a liver or heart disease before initiating the treatment. Notify your physician immediately if you develop fever, bruising under the skin (which may appear as red dots), unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, and seizures after taking this medicine. Limit exposure to sunlight and UV light while consuming Tacrocord 0.5mg Capsule by wearing appropriate protective clothing and sunscreen with a high sun protection factor. This is because of the potential risk of malignant skin changes with immunosuppressive therapy. This medicine may cause diarrhea; inform your physician if you have diarrhea for over a day. If you need to receive any vaccinations, consult your doctor once before receiving them.

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General Medicine

Dopacan Injection is a brand of Dopamine Hydrochloride, a potent vasopressor and inotropic agent used in critical care settings to manage various cardiovascular conditions. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dopacan Injection is indicated for: • Shock Management: Including septic shock, cardiogenic shock, and hypovolemic shock. • Acute Heart Failure: To improve cardiac output and perfusion. • Severe Hypotension: Especially in patients unresponsive to volume resuscitation. • Renal Protection: To enhance renal blood flow and urine output in certain critically ill patients. Dopamine works by stimulating dopaminergic and beta-adrenergic receptors, leading to increased heart rate, contractility, and renal perfusion. At higher doses, it also stimulates alpha-adrenergic receptors, causing vasoconstriction and increased blood pressure. ________________________________________ ⚙️ Dosage and Administration Dopacan Injection is administered intravenously, with the dosage tailored to the patient's condition and response: • Low Dose (1–5 mcg/kg/min): Primarily stimulates dopaminergic receptors, increasing renal blood flow and urine output. • Medium Dose (5–15 mcg/kg/min): Stimulates beta-1 adrenergic receptors, enhancing heart rate and contractility. • High Dose (15–50 mcg/kg/min): Stimulates alpha-1 adrenergic receptors, leading to vasoconstriction and increased blood pressure. Continuous monitoring of blood pressure, heart rate, and urine output is essential during administration. ________________________________________ ⚠️ Precautions and Contraindications Before using Dopacan Injection, inform your healthcare provider if you have: • Allergies to dopamine or other components of the injection. • A history of heart rhythm disorders or coronary artery disease. • Pheochromocytoma (a rare tumor of the adrenal glands). • Diabetes, asthma, or sulfite allergies. • Circulatory disorders such as Raynaud's disease or Buerger's disease. • Recent use of monoamine oxidase inhibitors (MAOIs). This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. ________________________________________ 💊 Side Effects Common side effects may include: • Palpitations or increased heart rate. • Nausea and vomiting. • Headache. • Difficulty breathing. • Gangrene (in rare cases, due to excessive vasoconstriction). Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.

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Anti Cancer Medicine

6-MP (6-Mercaptopurine) tablets are a prescription medication primarily used to treat certain types of cancers and autoimmune conditions by suppressing abnormal cell growth and activity. 💊 Primary Uses of 6-MP Tablets: ✅ 1. Acute Lymphoblastic Leukemia (ALL) Main use: Maintenance therapy after initial treatment. Function: Prevents cancer cells from growing and dividing. Often used in combination with other chemotherapy drugs. ✅ 2. Crohn’s Disease and Ulcerative Colitis (off-label) Used to suppress the immune system and reduce inflammation in the intestines. Helps in maintaining remission in chronic inflammatory bowel diseases. ✅ 3. Autoimmune Disorders (off-label) Occasionally used for diseases like systemic lupus erythematosus (SLE) or autoimmune hepatitis to control immune response. ⚙️ How It Works: 6-MP is an antimetabolite, which means it interferes with the normal metabolism of cells, especially fast-dividing ones like cancer or immune cells. It alters DNA and RNA synthesis, inhibiting cell replication. 📋 Important Notes: Requires regular blood tests to monitor liver function and white blood cell count. Dosage is highly individualized, based on body weight, condition, and blood work. Thiopurine methyltransferase (TPMT) enzyme activity may be tested before starting, as it affects how the body processes 6-MP. ⚠️ Possible Side Effects: Bone marrow suppression (low blood cells) Liver toxicity Nausea or vomiting Increased risk of infections Loss of appetite ❗ Precautions: Avoid alcohol and certain medications like allopurinol (unless adjusted by your doctor). Not safe during pregnancy unless absolutely necessary. Patients should report fever, fatigue, or unusual bruising/bleeding right away.

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Cats and Dogs

Taurians contains 2 potent anti-oxidants – N-acetyl cysteine & Taurine. Taurine is an amino acid that both dogs and cats require for good health. For cats, taurine is necessary for brain, nerves, eyes, heart, digestion, immune function and fetal development. For dogs, taurine is needed for eyes, reproduction, bile acid (for fat digestion) and for healthy heart. N-Acetylcysteine is useful in treating conditions that involve tissue damage due to oxidative stress and toxicity, Taurians helps to protect against damage from oxidative stress in patients with chronic kidney disease, reduces risk of cardiovascular disease, promotes healthy liver, prevents or reduces glomerular damage due to diabetes, and promotes clean & healthy lungs.

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Cats and Dogs

Electroytes help to carry out hundreds of critical proceses in the body. Loss of water results in electrolye imbalances and needs to be corrected with supplements. One of the most common reasons for water loss is dehydration related to heat stress. Redospet restores electrolyte balance in such hot weather conditions. Many common canine and feline health problems can also result in a loss of not only water but also electrolytes. Redospet helps to maintain hydration by providing electrolytes that help recovery from vomiting, diarrhea, and gastroenteritis. Redospet contains Bacillus coagulans, a probiotic bacteria that supports gut and immune health. Unlike standard Oral rehydration solutions (ORS), Redospet is formulated as per the latest WHO guidelines of the righ osmolarity of 245mOsmol/l and helps to reduce vomiting, stool output/volume and the need fo iv therapy.

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General Medicine

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

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General Medicine

Milrican 10 is a brand of Milrinone Lactate Injection, manufactured by American Remedies. Milrinone is a phosphodiesterase-3 (PDE3) inhibitor that serves as both an inotropic agent and a vasodilator. ________________________________________ ✅ Primary Uses of Milrican 10 Milrican 10 is indicated for the short-term intravenous treatment of: • Severe congestive heart failure: Particularly in patients unresponsive to conventional therapies. • Acute decompensated heart failure: Including low output states following cardiac surgery. It is commonly used in intensive care units or during cardiac procedures to support heart function. ________________________________________ ⚙️ Mechanism of Action Milrinone works by inhibiting PDE3, leading to increased cyclic AMP (cAMP) levels in cardiac and vascular smooth muscle cells. This results in: • Increased myocardial contractility: Enhancing the heart's ability to pump blood. • Vasodilation: Relaxing blood vessels, which reduces the heart's workload and improves blood flow. ________________________________________ ⚠️ Important Considerations • Administration: Milrican 10 should only be administered intravenously under the supervision of a healthcare professional. • Monitoring: Patients receiving Milrican 10 require close monitoring of blood pressure, heart rate, and kidney function. • Contraindications: Not recommended for patients with severe dehydration, electrolyte imbalances, or known hypersensitivity to milrinone. • Pregnancy and Breastfeeding: Consult a doctor before use if pregnant or breastfeeding.

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General Medicine

Frasix 40 injection belongs to a group of medicines called diuretics or water tablets. It is used to reduce the swelling (edema) caused by too much water in the body in people who have heart failure, liver or kidney disease. This medicine is also used to treat high blood pressure. Frasix 40 injection helps your body get rid of extra water and salt through urine. It may be used alone or in combination with other medicines as per the dose advised by your doctor. It can be taken with or without food and should be taken at the same time each day. It is best to avoid taking this medicine within 4 hours of your bedtime to prevent having to get up at night to urinate. It is important to continue taking this medication even if you feel well. If you stop taking it without consulting your doctor, your condition may worsen. Lifestyle changes like reducing stress, restricting salt intake, and stopping smoking may help this medication work better.

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Heart Disorder

Aggramed 5mg Infusion is a blood thinner which prevents formation of harmful blood clots. It helps to prevent a heart attack in patients presenting with severe chest pain due to a sudden decrease in blood flow to the heart. Aggramed 5mg Infusion is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. You should continue all your other medicines that are advised by the doctor for your long term treatment even after this injection. Common side effects of this medicine include headaches, hematoma, nausea, ecchymosis, postoperative bleeding, and blood in stool or urine. Let your doctor know immediately if you see pinpoint rash or blood in your vomits, urine, or stool.

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