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'synovial membrane leading'

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Eye Care

Tobi-D (Tobramycin with Dexamethasone) Eye Drops is a prescription ophthalmic solution combining an antibiotic and a corticosteroid to treat specific bacterial eye infections accompanied by inflammation. ________________________________________ ✅ Primary Uses Tobi-D is primarily used for: • Bacterial Conjunctivitis: Infection of the conjunctiva (the membrane covering the white part of the eye and the inner surface of the eyelids). • Keratitis: Infection of the cornea. • Post-surgical Infections: Prophylactic treatment or management of infections following eye surgeries. It addresses both the infection and the inflammation associated with these conditions. ________________________________________ 💊 Dosage and Administration • Standard Dosage: Instill 1–2 drops into the affected eye(s) every 4–6 hours, or as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Contraindications and Cautions • Contraindications: o Hypersensitivity to tobramycin, dexamethasone, or any component of the formulation. o Active viral infections of the eye, such as herpes simplex keratitis. o Untreated fungal or mycobacterial infections of the eye. • Cautions: o Use with caution in patients with a history of glaucoma, as corticosteroids can increase intraocular pressure. o Prolonged use may lead to cataract formation or secondary ocular infections. o Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. ________________________________________ 🧪 Mechanism of Action • Tobramycin: An aminoglycoside antibiotic that inhibits bacterial protein synthesis, leading to bacterial cell death. • Dexamethasone: A corticosteroid that reduces inflammation by inhibiting the release of inflammatory mediators. Together, these components address both the infection and the inflammation associated with certain eye conditions.

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Eye Care

FZ-3 Eye-Ear Drops containing Fluconazole are primarily used to treat fungal infections of the eyes and ears. Fluconazole is an antifungal medication that works by inhibiting the growth of fungi. 🔹 Primary Uses Fungal Eye Infections (Ophthalmic Fungal Infections) Fluconazole in eye drop form is used to treat fungal infections of the eye, such as fungal keratitis or endophthalmitis, which can cause inflammation, pain, and potentially lead to vision loss if left untreated. Fungal Ear Infections (Otomycosis) FZ-3 can be used for treating fungal ear infections, also known as otomycosis, which is often caused by fungi like Aspergillus or Candida. Symptoms include itching, pain, and discharge from the ear canal. 🔹 How It Works Fluconazole is an antifungal agent that works by inhibiting the fungal enzyme lanosterol 14α-demethylase, which is involved in the synthesis of ergosterol, an essential component of the fungal cell membrane. By blocking this enzyme, fluconazole disrupts the fungal cell membrane, leading to fungal cell death or inhibition of growth. ⚠️ Common Side Effects Eye: Mild eye irritation or burning sensation upon application Blurred vision (temporary) Redness or stinging in the eyes Ear: Mild ear irritation Ear itching or discomfort after application Temporary hearing changes (rare) If any of these side effects persist or worsen, consult your healthcare provider. 🔹 Usage Tips Dosage: Typically, 1–2 drops are applied to the affected eye or ear 2–3 times daily, as prescribed by your doctor. Application Instructions: Wash your hands thoroughly before applying the drops. For the eyes: Tilt your head back and gently pull down the lower eyelid to form a pocket. Instill the prescribed number of drops and gently close your eye for a few seconds. For the ears: Tilt your head to one side, apply the drops into the ear canal, and gently massage the ear to help the drops penetrate. If you are using other medications for the eyes or ears, wait about 5 minutes between applying each medication. Contact Lenses: If you wear contact lenses, remove them before applying the drops to avoid any contamination. You can reinsert your lenses after 15 minutes. 🔹 Precautions Allergies: If you have a known allergy to fluconazole or other azole antifungals, do not use the drops. Pregnancy and Breastfeeding: Fluconazole should be used with caution in pregnancy, particularly during the first trimester. Always consult your doctor if you are pregnant or breastfeeding. Underlying Conditions: Inform your healthcare provider if you have any liver or kidney diseases, as these conditions may affect how the medication works in your body. Systemic Absorption: Although FZ-3 is used topically, there is a possibility of systemic absorption. Monitor for any systemic side effects, especially with prolonged use.

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General Medicine

Colistican 3 Injection is an intravenous formulation containing Colistimethate Sodium 3 Million IU, manufactured by American Remedies. It is primarily used to treat severe infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 3 Injection Colistican 3 Injection is indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bloodstream Infections (Sepsis): Infections caused by resistant bacteria entering the bloodstream. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. • Intra-abdominal Infections: Such as peritonitis. • Cystic Fibrosis: For chronic pulmonary infections due to Pseudomonas aeruginosa in both adults and children. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

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Antibiotic Medicine

Colistican 2 Injection is a brand of Colistimethate Sodium for Injection, manufactured by American Remedies. It is a polymyxin-class antibiotic used to treat serious infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 2 Injection Colistican 2 Injection is primarily indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bacteremia (Bloodstream Infection): Infections caused by resistant bacteria entering the bloodstream. • Lower Respiratory Tract Infections: Including severe cases of pneumonia and bronchitis. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. These infections are typically caused by pathogens such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae, which are resistant to multiple antibiotics. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

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Antibiotic Medicine

Colistican 1 Injection is a brand of Colistimethate Sodium for Injection manufactured by American Remedies. Colistimethate sodium is a polymyxin-class antibiotic, also known as polymyxin E, used to treat serious infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 1 Injection Colistican 1 Injection is primarily used for: • Multidrug-Resistant Infections: Especially those caused by Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Urinary Tract Infections (UTIs): Caused by resistant Gram-negative bacteria. • Bloodstream Infections (Sepsis): Resulting from resistant pathogens. • Intra-abdominal Infections: Such as peritonitis. • Cystic Fibrosis: For chronic pulmonary infections due to Pseudomonas aeruginosa in both adults and children. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

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General Medicine

Ceforzone SB 1.5 Injection is a combination antibiotic formulation containing Cefoperazone (1000 mg) and Sulbactam (500 mg). Manufactured by American Remedies, it is primarily used to treat a wide range of bacterial infections. ________________________________________ 🩺 Uses of Ceforzone SB 1.5 Injection Ceforzone SB 1.5 Injection is indicated for the treatment of various bacterial infections, including: • Respiratory Tract Infections: Such as pneumonia and bronchitis. • Urinary Tract Infections: Including cystitis and pyelonephritis. • Intra-abdominal Infections: Such as peritonitis and abscesses. • Skin and Soft Tissue Infections: Including cellulitis and wound infections. • Bone and Joint Infections: Such as osteomyelitis and septic arthritis. • Meningitis: Infection of the membranes covering the brain and spinal cord. • Pelvic Inflammatory Disease: Infection of the female reproductive organs. • Gonorrhea: A sexually transmitted infection. Septicemia: Bloodstream infection. Surgical Prophylaxis: To prevent infections associated with major surgeries. ________________________________________ 💊 Mechanism of Action • Cefoperazone: A third-generation cephalosporin antibiotic that inhibits the synthesis of the bacterial cell wall, leading to cell lysis and death. Sulbactam: A beta-lactamase inhibitor that protects cefoperazone from enzymatic degradation by bacterial beta-lactamases, thereby enhancing its antibacterial activity. ________________________________________ ⚠️ Precautions • Allergy: Inform your healthcare provider if you have a history of allergic reactions to penicillins, cephalosporins, or beta-lactam antibiotics. • Liver or Kidney Impairment: Use with caution in patients with liver or kidney dysfunction. Dosage adjustments may be necessary. • Pregnancy and Breastfeeding: Consult your doctor before use during pregnancy or breastfeeding. • Drug Interactions: Inform your healthcare provider about all other medications you are taking to avoid potential interactions.

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General Medicine

Aone SB 1.5 gm Injection is a combination antibiotic manufactured by American Remedies. It contains Ceftriaxone (1000 mg) and Sulbactam (500 mg). Ceftriaxone is a third-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis, leading to cell death. Sulbactam is a β-lactamase inhibitor that protects Ceftriaxone from degradation by β-lactamase-producing bacteria, thereby enhancing its effectiveness. ________________________________________ 🩺 Uses of Aone SB 1.5 gm Injection Aone SB 1.5 gm Injection is prescribed for the treatment of various bacterial infections, including: • Lower Respiratory Tract Infections: Such as pneumonia. • Urinary Tract Infections (UTIs): Including both complicated and uncomplicated UTIs. • Intra-abdominal Infections: Such as peritonitis. • Skin and Soft Tissue Infections: Including cellulitis and abscesses. • Bone and Joint Infections: Such as osteomyelitis and septic arthritis. • Septicemia: Bloodstream infections. • Meningitis: Infections of the brain and spinal cord membranes. • Pelvic Inflammatory Disease: Infections of the female reproductive organs. • Endocarditis: Infection of the heart valves. • Surgical Prophylaxis: To prevent infections during or after surgery. ________________________________________ 💊 How It Works Ceftriaxone works by inhibiting the synthesis of bacterial cell walls, leading to the destruction of the bacteria. Sulbactam enhances the activity of Ceftriaxone by inhibiting β-lactamase enzymes that can degrade Ceftriaxone, thereby extending its spectrum of activity against resistant bacteria. ________________________________________ ⚠️ Side Effects Common side effects may include: • Injection site reactions (pain, redness, or swelling). • Diarrhea. • Rash. • Increased liver enzymes. • Low blood platelets. • Changes in white blood cell counts. If any of these side effects persist or worsen, consult your healthcare provider promptly. ________________________________________ ⚠️ Precautions Before using Aone SB 1.5 gm Injection, inform your doctor if you: • Have a history of allergies to cephalosporin antibiotics. • Have liver or kidney disease. • Are pregnant, planning to become pregnant, or breastfeeding. • Are taking any other medications, including over-the-counter drugs and supplements. Your doctor will determine the appropriate dosage and duration of treatment based on your specific condition.

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Steroid/Hormones Medicines

Bulkonan Injection is typically an anabolic steroid formulation, often based on Nandrolone Decanoate, commonly used in bodybuilding and strength training circles. It is not intended for general medical use without strict supervision. ✅ Common Uses: Muscle Growth Enhances muscle protein synthesis, leading to significant muscle mass gain over time. Strength Enhancement Increases physical strength and training performance, especially in resistance workouts. Recovery Support Speeds up post-workout recovery, helping reduce muscle soreness and fatigue. Joint Support Some users report relief from joint pain, likely due to the compound’s ability to increase synovial fluid retention. Improved Endurance By increasing red blood cell production, it can improve oxygen delivery and stamina during workouts.

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