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'rare cases'

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General Medicine

Procitil Injection is a medication that contains Prochlorperazine, a phenothiazine class drug. It is primarily used to treat: 1. Severe Nausea and Vomiting Procitil is effective in managing nausea and vomiting caused by various conditions, including: • Post-operative recovery • Chemotherapy-induced nausea • Gastrointestinal disorders 2. Psychotic Disorders Prochlorperazine, the active ingredient in Procitil, has antipsychotic properties and is used to manage symptoms of: • Schizophrenia • Delirium • Severe anxiety 3. Vertigo and Dizziness It helps alleviate dizziness and balance issues associated with inner ear problems. 4. Severe Anxiety Procitil can be used in the short-term management of severe anxiety when other treatments are not effective. 5. Hiccups In some cases, Procitil is used to treat persistent and severe hiccups. Administration Procitil Injection is administered intravenously or intramuscularly by a healthcare professional. The dosage and frequency depend on the specific condition being treated and the patient's response to therapy. Side Effects Common side effects may include: • Drowsiness or sedation • Dizziness • Dry mouth • Constipation • Blurry vision • Muscle stiffness or tremors • Serious side effects are rare but can include: • Severe allergic reactions • Neuroleptic malignant syndrome (a life-threatening condition) • Tardive dyskinesia (involuntary movements) If you experience any unusual symptoms, contact your healthcare provider immediately. Precautions Before using Procitil Injection, inform your doctor if you have: • Allergies to prochlorperazine or other phenothiazines • Liver or kidney disease • Heart problems • Seizure disorders • Parkinson's disease • Pregnancy or breastfeeding status

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General Medicine

Mucanix Injection is a brand of Acetylcysteine Injection, manufactured by American Remedies. Acetylcysteine is a mucolytic agent that helps in thinning and loosening mucus in the airways, making it easier to cough up and clear the airways. ________________________________________ ✅ Primary Uses Mucanix Injection is primarily used for: • Respiratory Disorders: Conditions such as chronic bronchitis, asthma, and cystic fibrosis, where there is excessive mucus production. • Paracetamol (Acetaminophen) Overdose: As an antidote to prevent liver damage when administered within 8 hours of overdose. ________________________________________ ⚙️ Mechanism of Action Acetylcysteine works by: • Breaking down mucus: It reduces the viscosity of mucus, facilitating easier expectoration. • Restoring glutathione levels: In cases of paracetamol overdose, it replenishes glutathione, a vital antioxidant, aiding in detoxification and protecting the liver. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Allergy: Do not use if allergic to acetylcysteine or any of its components. • Asthma: Use with caution in patients with asthma; monitoring is required. • Pregnancy and Breastfeeding: Consult a doctor before use during pregnancy or breastfeeding. Common Side Effects: • Nausea • Vomiting • Rash • Fever • Headache Serious Side Effects: • Anaphylactic reactions (rare) • Hypotension • Tachycardia If you experience any of these serious side effects, seek immediate medical attention.

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Eye Care

Dorzopar Eye Drops containing Dorzolamide 2% are primarily used to lower intraocular pressure (IOP) in individuals with glaucoma or ocular hypertension (high eye pressure). Here's a detailed breakdown of its uses: 🔹 Primary Uses Open-Angle Glaucoma Dorzolamide is a carbonic anhydrase inhibitor that helps reduce the production of aqueous humor (the fluid inside the eye). By decreasing the amount of fluid produced, it lowers the intraocular pressure (IOP), which is important in treating open-angle glaucoma. Glaucoma is a condition where high eye pressure can damage the optic nerve and lead to vision loss. Ocular Hypertension Dorzopar is also used for the treatment of ocular hypertension, a condition in which the eye pressure is elevated but glaucoma has not yet developed. Lowering eye pressure helps prevent the progression to glaucoma. 🔹 How It Works Dorzolamide works by inhibiting the carbonic anhydrase enzyme in the eye. This enzyme is involved in the production of aqueous humor. By blocking this enzyme, Dorzolamide reduces the amount of fluid produced inside the eye, which in turn lowers the eye pressure. ⚠️ Common Side Effects Eye irritation, burning, or stinging upon application Blurred vision (temporary) Redness in the eyes or foreign body sensation Dry eyes or increased tear production Headaches or dizziness (in some cases) Taste disturbance (a bitter taste in the mouth) 🔹 Usage Tips Dosage: Typically, 1 drop in each affected eye, twice daily (morning and evening), or as prescribed by your healthcare provider. Application Instructions: Wash your hands thoroughly before applying the drops. Tilt your head back slightly and pull down your lower eyelid to form a small pocket. Place one drop in the pocket without touching the dropper tip to your eye. Gently close your eye and blink a few times to help spread the medication. If using other eye medications, wait 5–10 minutes between applications. Contact Lenses: Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them. 🔹 Precautions Kidney or Liver Problems: Since Dorzolamide is metabolized in the body, it should be used with caution in individuals with kidney or liver issues. Pregnancy and Breastfeeding: Consult your doctor before using this medication if you are pregnant or breastfeeding, as the safety of Dorzolamide during pregnancy or while breastfeeding has not been fully established. Eye Infections: Be cautious if you have an eye infection, as Dorzolamide may not be suitable for some active infections. Systemic Effects: While Dorzolamide is generally applied locally to the eye, some systemic absorption may occur, leading to side effects like metabolic acidosis (rare). It should be used cautiously in patients with a history of diabetes, kidney disease, or respiratory problems.

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Anti-cancer medicines

Cytoblastin 10mg Injection is an anti-cancer medication used in the treatment of breast cancer, kidney cancer, Hodgkin’s disease, and Non-Hodgkin's lymphoma. Cytoblastin 10mg Injection is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include nausea, vomiting, diarrhea, and decreased appetite. This medicine may reduce the number of blood cells (white blood cells) in your blood, thereby, increasing the susceptibility to infections and fever. In some cases, it may also cause kidney disease related to uric acid level. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You should take precautions while taking this medication as it may cause inflammation of mouth and lips and neurological toxicity. Uses of Cytoblastin Injection Breast cancer Non-Hodgkin lymphoma (NHL) Non-small cell lung cancer Pancreatic cancer Kidney cancer Hodgkin’s disease Blood cancer Lymphomas Wilms' tumor Bone cancer Benefits of Cytoblastin Injection In Non-Hodgkin lymphoma (NHL) Non-Hodgkin's lymphoma is a cancer of the white blood cells in our body, also called mantle-cell lymphoma. White blood cells are those cells that help us to fight infections. Cytoblastin 10mg Injection helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and further spread. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to. Side effects of Cytoblastin Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Cytoblastin Nausea Vomiting Decreased appetite Decreased white blood cell count Diarrhea How to use Cytoblastin Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Cytoblastin Injection works Cytoblastin 10mg Injection blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Cytoblastin 10mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Cytoblastin 10mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Cytoblastin 10mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Cytoblastin 10mg Injection may cause side effects which could affect your ability to drive. warnings Kidney SAFE IF PRESCRIBED Cytoblastin 10mg Injection is safe to use in patients with kidney disease. No dose adjustment of Cytoblastin 10mg Injection is recommended. However, talk to your doctor if you have any underlying kidney disease. warnings Liver CAUTION Cytoblastin 10mg Injection should be used with caution in patients with liver disease. Dose adjustment of Cytoblastin 10mg Injection may be needed. Please consult your doctor. Use of Cytoblastin 10mg Injection may not be advised in patients with severe liver disease.

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General Medicine

Dopacan Injection is a brand of Dopamine Hydrochloride, a potent vasopressor and inotropic agent used in critical care settings to manage various cardiovascular conditions. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dopacan Injection is indicated for: • Shock Management: Including septic shock, cardiogenic shock, and hypovolemic shock. • Acute Heart Failure: To improve cardiac output and perfusion. • Severe Hypotension: Especially in patients unresponsive to volume resuscitation. • Renal Protection: To enhance renal blood flow and urine output in certain critically ill patients. Dopamine works by stimulating dopaminergic and beta-adrenergic receptors, leading to increased heart rate, contractility, and renal perfusion. At higher doses, it also stimulates alpha-adrenergic receptors, causing vasoconstriction and increased blood pressure. ________________________________________ ⚙️ Dosage and Administration Dopacan Injection is administered intravenously, with the dosage tailored to the patient's condition and response: • Low Dose (1–5 mcg/kg/min): Primarily stimulates dopaminergic receptors, increasing renal blood flow and urine output. • Medium Dose (5–15 mcg/kg/min): Stimulates beta-1 adrenergic receptors, enhancing heart rate and contractility. • High Dose (15–50 mcg/kg/min): Stimulates alpha-1 adrenergic receptors, leading to vasoconstriction and increased blood pressure. Continuous monitoring of blood pressure, heart rate, and urine output is essential during administration. ________________________________________ ⚠️ Precautions and Contraindications Before using Dopacan Injection, inform your healthcare provider if you have: • Allergies to dopamine or other components of the injection. • A history of heart rhythm disorders or coronary artery disease. • Pheochromocytoma (a rare tumor of the adrenal glands). • Diabetes, asthma, or sulfite allergies. • Circulatory disorders such as Raynaud's disease or Buerger's disease. • Recent use of monoamine oxidase inhibitors (MAOIs). This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. ________________________________________ 💊 Side Effects Common side effects may include: • Palpitations or increased heart rate. • Nausea and vomiting. • Headache. • Difficulty breathing. • Gangrene (in rare cases, due to excessive vasoconstriction). Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.

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General Medicine

Dobutacan 12 Injection is a brand of Dobutamine Hydrochloride 12.5 mg/mL, a synthetic catecholamine used in critical care settings to support heart function. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dobutacan 12 Injection is indicated for: • Cardiac Decompensation: Acute heart failure due to conditions like myocardial infarction, cardiomyopathies, or post-cardiac surgery. • Cardiogenic Shock: A state of low cardiac output leading to inadequate tissue perfusion. • Septic Shock: A severe infection causing low blood pressure and organ dysfunction. • Stress Echocardiography: As a pharmacological agent to assess coronary artery disease when exercise is not feasible. It works by stimulating beta-1 adrenergic receptors, increasing heart contractility and stroke volume, thereby improving cardiac output. ________________________________________ ⚙️ Dosage and Administration Dobutacan 12 Injection is administered intravenously in a hospital setting. The typical dosage ranges from 2.5 to 10 mcg/kg/min, adjusted based on the patient's response. In some cases, doses up to 20 mcg/kg/min may be required. ________________________________________ ⚠️ Precautions and Contraindications Before using Dobutacan 12 Injection, inform your healthcare provider if you have: • Allergies to dobutamine or other components of the injection. • A history of arrhythmias or heart disease. • Kidney or liver problems. • A history of stroke or blood clots. This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. It is usually given as an intramuscular (IM) or intravenous (IV) injection. ________________________________________ 💊 Side Effects Common side effects may include: • Headache • Nausea or vomiting • Dizziness or lightheadedness • Injection site reactions (pain, redness, or swelling) Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.

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General Medicine

Bluecan Injection is a brand of Methylene Blue Injection, primarily used in medical settings for its diagnostic and therapeutic properties. ________________________________________ 🩺 Uses of Bluecan Injection 1. Treatment of Methemoglobinemia: Methylene Blue is the first-line treatment for methemoglobinemia, a condition where methemoglobin levels are elevated, impairing oxygen delivery to tissues. It acts as a reducing agent, converting methemoglobin back to hemoglobin, thereby restoring normal oxygen transport. 2. Urinary Tract Infections (UTIs): It is sometimes used as a urinary antiseptic to treat UTIs, although its use for this purpose has become less common with the advent of more effective antibiotics. 3. Surgical Dye: In surgical procedures, Methylene Blue is used as a dye to delineate tissues, identify sentinel lymph nodes, or assess organ perfusion. 4. Diagnostic Tool: It is used in diagnostic procedures to assess the function of certain organs, such as the kidneys, and to evaluate the patency of ducts. ________________________________________ ⚠️ Side Effects While generally well-tolerated, potential side effects of Methylene Blue Injection include: • Injection site reactions (pain, redness, swelling) • Headache • Dizziness • Nausea or vomiting • Skin discoloration (temporary blue or greenish tint) • In rare cases, serotonin syndrome, especially if used with serotonergic drugs ________________________________________ 💊 Mechanism of Action Methylene Blue acts by accepting electrons and donating them to reduce methemoglobin back to hemoglobin. This process restores the oxygen-carrying capacity of the blood. It also inhibits certain enzymes and has antimicrobial properties, which contribute to its use in treating infections. ________________________________________ ⚠️ Precautions • Drug Interactions: Avoid concurrent use with serotonergic drugs (e.g., SSRIs, SNRIs, MAO inhibitors) to prevent serotonin syndrome. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. • G6PD Deficiency: Use with caution in individuals with glucose-6-phosphate dehydrogenase deficiency, as it may cause hemolysis. • Renal Impairment: Dosage adjustments may be necessary in patients with kidney dysfunction

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General Medicine

Methylene Blue Injection is a versatile medication with several clinical uses. It’s a synthetic dye that also functions as a medicinal agent, especially in emergency and critical care settings. ✅ Primary Medical Uses of Methylene Blue Injection Methemoglobinemia Treatment Main use: It rapidly treats methemoglobinemia, a condition where hemoglobin can’t carry oxygen effectively. Converts methemoglobin (Fe³⁺) back to normal hemoglobin (Fe²⁺), restoring oxygen delivery. Urinary Tract Antiseptic (rarely used today) Has mild antiseptic properties in the urinary tract when used with other agents. Ifosfamide-Induced Encephalopathy Used off-label to counteract neurotoxicity caused by the chemotherapy drug ifosfamide. Intraoperative Staining Agent Surgeons and urologists may use it to identify structures (e.g., fistulas, ureters, sentinel lymph nodes). Vasoplegic Syndrome in Cardiac Surgery (off-label) Helps raise blood pressure in cases of refractory hypotension after heart surgery, by inhibiting nitric oxide pathways. Diagnostic Aid Sometimes used to help visualize certain body structures or to test for leaks (like gastrointestinal perforations). ⚠️ Important Warnings & Precautions Serotonin Syndrome Risk: Methylene blue is a monoamine oxidase inhibitor (MAOI) — do not use with SSRIs, SNRIs, or other serotonergic drugs. G6PD Deficiency: Can cause hemolysis in people with glucose-6-phosphate dehydrogenase deficiency. Pregnancy: Generally avoided unless absolutely necessary. 💉 Side Effects Pain at the injection site Nausea, vomiting Headache, dizziness Blue or green discoloration of urine, stool, or skin (temporary and harmless) High doses: confusion, agitation, or chest pain

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Eye Care

Atropine Sulphate Eye Drops IP refers to atropine sulfate in its pharmaceutical grade form, used specifically for ocular (eye) treatments. 'IP' stands for Indian Pharmacopoeia, which is a set of standards for medicines in India, ensuring quality, safety, and efficacy. Uses of Atropine Sulphate Eye Drops IP: Pupil Dilation (Mydriasis): One of the most common uses of atropine eye drops is to dilate the pupil for diagnostic purposes, especially during an eye examination. The drops relax the muscles in the eye, allowing for better visibility of the retina and optic nerve. Treatment of Uveitis and Iritis: Atropine is frequently prescribed for conditions such as uveitis and iritis (inflammation of the iris). The medication helps relieve pain and inflammation and prevents the iris from sticking to the lens. This is important to avoid complications like synechiae (adhesions between the iris and lens). Cycloplegia: Cycloplegia is the paralysis of the ciliary muscle that controls focusing. Atropine is used to temporarily paralyze this muscle during eye exams to assess the retina or the overall refractive status of the eye. Prevention of Post-Surgical Complications: After certain eye surgeries, atropine can help in preventing the formation of adhesions between the iris and the lens, which can occur after surgery like cataract surgery. It aids in recovery and minimizes the risk of complications. Management of Myopia (Nearsightedness): In some cases, atropine drops have been used in research to slow the progression of myopia (nearsightedness) in children, though this is less common in routine practice. How It Works: Atropine is an anticholinergic drug that blocks the action of acetylcholine, a neurotransmitter involved in eye muscle contraction. By inhibiting the contraction of the pupil’s sphincter muscle and the ciliary muscle, atropine causes pupil dilation and paralysis of accommodation, allowing for eye relaxation and easier examination. Dosage: The dosage depends on the condition being treated. Typically, for eye exams, one or two drops are applied to each eye, and the effects (pupil dilation) usually last for several hours. For therapeutic use, your doctor will prescribe the frequency and duration based on the specific condition. Precautions: Side Effects: Common side effects include blurred vision, sensitivity to light (photophobia), and dry mouth. In some cases, you may experience increased intraocular pressure or tachycardia (rapid heart rate). Avoid Exposure to Bright Light: Since atropine causes pupil dilation, you may be more sensitive to light. It's advisable to wear sunglasses when outside in bright conditions. Do Not Drive: Due to blurred vision, avoid driving or operating heavy machinery until the effects wear off. Systemic Effects: Rarely, atropine can be absorbed into the bloodstream, leading to symptoms such as confusion, rapid heart rate, or dry skin. If you experience these symptoms, seek medical help immediately. Contraindications: Glaucoma: Atropine should be used with caution, or avoided, in individuals with narrow-angle glaucoma or other eye conditions that affect intraocular pressure. Pregnancy and Breastfeeding: While atropine is generally considered safe in therapeutic doses, it’s essential to consult your doctor if you are pregnant or breastfeeding before using the drops.

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