Introduction to Tafero 25mg Tablet Tafero 25mg Tablet is an antiviral medication containing the active constituent Tenofovir alafenamide. It is used to treat chronic hepatitis B virus (HBV) infection. Hepatitis B is an infection affecting the liver caused by the hepatitis B virus. Discuss with your doctor about the precautions needed to avoid infecting others. Tell your doctor if you have or have ever had kidney diseases, liver diseases, or HIV before taking Tafero 25mg Tablet. Administration of this medicine may lead to lactic acidosis (accumulation of excessive acid) and hepatomegaly (enlarged liver). It is not recommended for patients weighing less than 35 kg. This medicine contains lactose. Contact your doctor if you are intolerant to sugars before taking medicine. Tell your doctor if you are breastfeeding or pregnant before taking Tafero 25mg Tablet. Do not stop taking this medicine without your doctor’s advice, as it may worsen the condition. The safety and efficacy of this medication in pediatric patients may differ from those in adults. Dosage adjustments and careful monitoring may be necessary for children and the elderly. Uses of Tafero 25mg Tablet Tafero 25mg Tablet is used in the treatment of: Hepatitis B virus (HBV) infection Therapeutic Effects of Tafero 25mg Tablet Its therapeutic effect of Tafero 25mg Tablet involves reducing viral replication, lowering a viral load, preserving the immune system, and delaying disease progression in individuals with HIV-1 or HBV. Interaction of Tafero 25mg Tablet with other drugs Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Tafero 25mg Tablet, reducing effectiveness by causing undesirable side effects. More Information about Tafero 25mg Tablet Store at temprature between 20°C to 25°C (68°F to 77°F). Keep away from moisture, heat, and light. It should not be frozen. Keep it in its original packaging. Keep away from children and pets. How to consume Tafero 25mg Tablet To consume Tafero 25mg Tablet properly, follow your healthcare provider's instructions regarding dosage, frequency, and duration. Take it with or without food, swallowing the tablets or capsules with water. Adhere to the prescribed dosing schedule; do not alter the dosage without consulting your healthcare provider. Safety Advices for Tafero 25mg Tablet Image Not Available Pregnancy If you are pregnant or planning to become pregnant, it is crucial to consult with your healthcare provider before taking Tafero 25mg Tablet. Image Not Available Breast Feeding Tafero 25mg Tablet is excreted into human breast milk, but the potential risks to the infant are not well established. So it is better to consult a doctor before taking it. Image Not Available Lungs If you have a history of lung disease or are experiencing respiratory symptoms while taking, it is important to consult your healthcare provider for a thorough evaluation before taking Tafero 25mg Tablet. Image Not Available Liver The safety of Tafero 25mg Tablet in individuals with liver disease may depend on the specific type and severity of liver disease and other factors. It is important to consult with a healthcare provider Image Not Available Alcohol It is generally recommended to avoid excessive alcohol consumption while taking Tafero 25mg Tablet or any medication. Alcohol can interact with this medication and affect liver function. Image Not Available Driving People may experience side effects such as dizziness, drowsiness, or fatigue while taking Tafero 25mg Tablet. Suppose you experience any of these side effects or any other symptoms that may interfere with your ability to drive safely. In that case, avoid driving or operating heavy machinery. Side Effects of Tafero 25mg Tablet Tafero 25mg Tablet causes some side effects like all medications, although not everyone will experience them. Serious: Too much lactic acid in the blood (unusual weakness, muscle pain, cold hands and feet) Severe liver problems (yellow skin and eyes, tea-colored urine, light-colored stools, loss of appetite) Severe kidney problems Common: Nausea, vomiting Diarrhea Stomach pain, joint pain Rash, itching Feeling tired Headache, dizziness

RIBOREA CAPSULE contains Hydroxyurea, which belongs to a group of medicines called Antimetabolites. It is used to manage resistant chronic myeloid leukaemia and locally advanced squamous cell cancer of the head and neck (excluding the lip) and cervical cancer. RIBOREA CAPSULE is not recommended for use in patients with a history of any blood problems or severe anaemia. RIBOREA CAPSULE should be used with caution in patients with liver, lung or kidney disease and myelosuppression (leukopenia, thrombocytopenia, anaemia). RIBOREA CAPSULE is not recommended for use during pregnancy. RIBOREA CAPSULE is not recommended for use by breastfeeding women. RIBOREA CAPSULE is also not recommended for use in children as its safety and effectiveness are not established. RIBOREA CAPSULE should be used with caution in the elderly aged 65 years or above. The most common side effects of taking RIBOREA CAPSULE are loss of appetite, weakness, loss of energy, sickness, diarrhoea, constipation, abdominal pain, hair loss, blood disorders (decrease in white blood cells, red blood cells and platelets), low back pain, black tarry stools or blood in the stools, unusual bleeding or bruising, muscle weakness, sores on the lips or mouth etc. Contact your physician if any of the symptoms worsen.

Marketer Hetero Healthcare Limited SALT COMPOSITION Fulvestrant (250mg) Storage Store in a refrigerator (2 - 8°C). Do not freeze. Uses of Fulzos Injection Breast cancer Product introduction Fulzos 250mg Injection is an estrogen blocker. It is used in the treatment of breast cancer in women who have gone through menopause. It works by adjusting the level of estrogen and slow down the growth of cancer cells. Fulzos 250mg Injection is given as an injection into the muscles under the supervision of a doctor. It should be taken as doctor your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. The most common side effects of this medicine include injection site reaction, headache, vomiting, allergic reaction, and nausea. If these bother you, or appear serious, let your doctor know. There may be ways of reducing or preventing them. Before taking this medicine, tell your doctor if you ever had kidney or liver disease or had bleeding disorder or had any blood clotting medicine. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant, planning pregnancy or breastfeeding. Side effects of Fulzos Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Fulzos Nausea Vomiting Back pain Fatigue Hot flashes Decreased appetite Constipation Bone pain Joint pain Cough Injection site pain Headache Pain in extremity Musculoskeletal (bone, muscle or joint) pain Breathlessness Increased alanine aminotransferase Increased aspartate aminotransferase Weakness How to use Fulzos Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Fulzos Injection works Fulzos 250mg Injection blocks the action of estrogen on breast cancer cells. This can lower or stop the growth of some breast cancer cells that need estrogen to grow. Safety advice warnings Alcohol CAUTION Caution is advised when consuming alcohol with Fulzos 250mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Fulzos 250mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Fulzos 250mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving SAFE Fulzos 250mg Injection does not usually affect your ability to drive. warnings Kidney CAUTION Fulzos 250mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Fulzos 250mg Injection may be needed. Please consult your doctor. Limited information is available on the use of Fulzos 250mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease. warnings Liver CAUTION Fulzos 250mg Injection should be used with caution in patients with liver disease. Dose adjustment of Fulzos 250mg Injection may be needed. Please consult your doctor.

INTRODUCTION ABOUT TAXONAB 100MG INJECTION TAXONAB 100MG INJECTION contains Paclitaxel which belongs to a group of anti-cancer medicines called Taxanes. TAXONAB 100MG INJECTION is used to manage ovarian and breast cancer as a first line of therapy and as a second line of management when platinum containing medicines (such as cisplatin) or anthracyclines are insufficient to manage the disease in affected individuals. TAXONAB 100MG INJECTION is also used to manage advanced NSCLC (non-small cell lung cancer) when surgery/radiation therapy is not suitable. The medicine is also indicated for use to manage AIDS-related Kaposi’s sarcoma when other managements (such as anthracyclines) are insufficient to manage the disease in affected individuals. TAXONAB 100MG INJECTION is not recommended for use in patients allergic to paclitaxel and polyoxyethylated castor oil. It is also not recommended for use in patients with few white blood cells count and serious & uncontrolled infection. The medicine is also not used in patients suffering from severe liver disease. Before receiving TAXONAB 100MG INJECTION, inform your doctor if you had previously received radiation to your chest and/or suffering from thrombocytopenia (low platelet count)/acute infections (such as herpes zoster, chickenpox, herpes), kidney problems (such as chronic kidney disease), liver problems (such as mild/moderate hepatic impairment) and/or heart problems (such as severe coronary artery disease, myocardial infarction and arrhythmias). TAXONAB 100MG INJECTION is not recommended for use during pregnancy. Women of child-bearing potential should use effective contraception method while receiving TAXONAB 100MG INJECTION which should be continued for next-6 months after completing the management. The medicine is also not recommended for use in breastfeeding women. TAXONAB 100MG INJECTION is also not recommended for use in children and adolescents (aged below 18 years). The medicine can be used with caution in elderly patients (aged above 65 years) after consulting the doctor. The most common side effects of receiving TAXONAB 100MG INJECTION are minor allergic reactions (such as flushing, rash, itching), shortness of breath, sore throat/mouth ulcers, diarrhea, nausea, vomiting and/or loss of hair. Consult your doctor if any of these symptoms worsen. USES OF TAXONAB 100MG INJECTION Manage ovarian and breast cancer. Manage advanced NSCLC (non-small cell lung cancer) Manage AIDS-related Kaposi’s sarcoma in affected individuals. HOW TAXONAB 100MG INJECTION WORKS TAXONAB 100MG INJECTION works by interfering with the microtubule structures in the cell (substance which aids cancer cells to divide and multiply) thus inhibiting the growth of cancer cells and managing its spread in affected individuals. DIRECTIONS FOR USE TAXONAB 100MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF TAXONAB 100MG INJECTION COMMON minor allergic reactions such as flushing, rash and/or itching infections such as upper respiratory infection, urinary tract infection shortness of breath sore throat/mouth ulcers, sore and red mouth diarrhea, nausea, vomiting loss of hair pain in the muscles, cramps, joints fever, severe chills, headache, dizziness, tiredness, looking pale bleeding, bruising more easily than normal signs of peripheral neuropathy such as numbness, tingling/weakness in arms and legs temporary mild nail change and skin changes reactions at injection sites such as localized swelling, pain and/or redness of the skin. UNCOMMON septic shock (severe drop in blood pressure) due to infections racing heartbeat, rapid beating of the heart, respiratory distress, heart attack, heart block fatigue, sweating, fainting, significant allergic reactions, phlebitis (inflammation of a vein), swelling of the face, lips, mouth, tongue and/or throat back pain, chest pain, pain around hands and feet, chills, abdominal pain. RARE febrile neutropenia (type of fever) due to low white blood cell count associated with fever and increased risk of infection motor neuropathy (disease that affects your body’s motor nerves) pulmonary embolism (blockade of lung artery), lung fibrosis (damaged/scarred lung tissue), interstitial pneumonia (scarring of lung tissue), pleural effusion (build of fluid between lungs and chest) bowel obstruction, bowel perforation, inflammation of colon, inflammation of the pancreas (pancreatitis) skin redness peritonitis (inflammation of abdominal layer) fever, dehydration, weakness anaphylactic reactions (life threatening allergic reaction). HOW TO MANAGE SIDE EFFECTS Diarrhea: Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult your doctor and inform them if the symptom gets worse.

Marketer Getwell Pharma (I) Pvt Ltd SALT COMPOSITION Docetaxel (20mg) Storage Store in a refrigerator (2 - 8°C). Do not freeze. Uses of Taxewell Injection Breast cancer Non-small cell lung cancer Prostate cancer Cancer of head and neck Product introduction Taxewell 20mg Injection is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of head and neck. Taxewell 20mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Some of the common side effects of this medicine include breathlessness, constipation, edema (swelling), infection, loss of appetite, muscle pain, nail disorder, pain, and weakness. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function. Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine. Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Benefits of Taxewell Injection In Breast cancer Taxewell 20mg Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Taxewell 20mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you. In Non-small cell lung cancer Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Taxewell 20mg Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated. In Prostate cancer Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Taxewell 20mg Injection decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate. In Cancer of head and neck Head and neck cancer includes cancer of the mouth, nose, sinuses or throat. Taxewell 20mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but it has some bothersome side effects. Therefore, you should discuss the risks and benefits with your doctor.

Marketer Samarth Life Sciences Pvt Ltd SALT COMPOSITION Leuprolide (22.5mg) Salt Synonyms Leuprorelin Storage Store in a refrigerator (2 - 8°C). Do not freeze. Uses of Leulide Injection Prostate cancer Endometriosis Uterine fibroids Precocious puberty (premature puberty) Female infertility Product introduction Leulide Depot 22.5mg Injection is used in the treatment of prostate cancer. It is also used to treat endometriosis (endometrium of the uterus grows excessively and causes symptoms like pain, heavy or irregular periods), uterine fibroids and central precocious puberty (very early puberty). Leulide Depot 22.5mg Injection is given as an injection under the skin by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Decreased libido, increased sweating, fatigue, muscle weakness, and hot flashes are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment. Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Side effects of Leulide Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Leulide Decreased libido Testicular atrophy Increased sweating Fatigue Muscle weakness Erectile dysfunction Hot flashes How to use Leulide Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Leulide Injection works Leulide Depot 22.5mg Injection reduces the amount of sex hormones (testosterone in men and estrogen in women). It works by decreasing the blood levels of testosterone in males. Leulide Depot 22.5mg Injection also acts by shutting off hormones made by the ovaries (female reproductive organs), so the estrogen (one of the hormones that causes females to have periods) level is lowered.

Marketer Sun Pharmaceutical Industries Ltd SALT COMPOSITION Leuprolide (11.25mg) Salt Synonyms Leuprorelin Storage Store below 25°C Uses of Lupride Injection Prostate cancer Endometriosis Uterine fibroids Precocious puberty (premature puberty) Female infertility Product introduction Lupride Depot 11.25mg Injection is used in the treatment of prostate cancer. It is also used to treat endometriosis (endometrium of the uterus grows excessively and causes symptoms like pain, heavy or irregular periods), uterine fibroids and central precocious puberty (very early puberty). Lupride Depot 11.25mg Injection is given as an injection under the skin by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Decreased libido, increased sweating, fatigue, muscle weakness, and hot flashes are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment. Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Side effects of Lupride Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Lupride Decreased libido Testicular atrophy Increased sweating Fatigue Muscle weakness Erectile dysfunction Hot flashes How to use Lupride Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Lupride Injection works Lupride Depot 11.25mg Injection reduces the amount of sex hormones (testosterone in men and estrogen in women). It works by decreasing the blood levels of testosterone in males. Lupride Depot 11.25mg Injection also acts by shutting off hormones made by the ovaries (female reproductive organs), so the estrogen (one of the hormones that causes females to have periods) level is lowered.

Colistican 3 Injection is an intravenous formulation containing Colistimethate Sodium 3 Million IU, manufactured by American Remedies. It is primarily used to treat severe infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 3 Injection Colistican 3 Injection is indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bloodstream Infections (Sepsis): Infections caused by resistant bacteria entering the bloodstream. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. • Intra-abdominal Infections: Such as peritonitis. • Cystic Fibrosis: For chronic pulmonary infections due to Pseudomonas aeruginosa in both adults and children. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

Colistican 2 Injection is a brand of Colistimethate Sodium for Injection, manufactured by American Remedies. It is a polymyxin-class antibiotic used to treat serious infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 2 Injection Colistican 2 Injection is primarily indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bacteremia (Bloodstream Infection): Infections caused by resistant bacteria entering the bloodstream. • Lower Respiratory Tract Infections: Including severe cases of pneumonia and bronchitis. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. These infections are typically caused by pathogens such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae, which are resistant to multiple antibiotics. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness