Paricar (Pilocarpine Nitrate 4%) Eye Drops are a miotic ophthalmic solution primarily used to manage certain eye conditions by reducing intraocular pressure. ________________________________________ 🔍 Uses 1. Treatment of Glaucoma and Ocular Hypertension Pilocarpine Nitrate 4% is employed to lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It facilitates the drainage of aqueous humor from the eye, thereby reducing IOP and helping prevent vision loss and nerve damage. 2. Management of Acute Angle-Closure Glaucoma In acute angle-closure glaucoma, Pilocarpine Nitrate 4% may be used to constrict the pupil, facilitating the opening of the angle between the iris and cornea, which helps in reducing IOP. 3. Induction of Miosis Pilocarpine Nitrate 4% is utilized to induce miosis (pupil constriction) during certain eye surgeries or to reverse the effects of drugs used to dilate the pupil during eye examinations. ________________________________________ 💧 Dosage and Administration • General Dosage: Instill one drop into the affected eye(s) 1 to 4 times daily, as directed by your healthcare provider. • Application Method: 1. Wash your hands thoroughly before use. 2. Tilt your head back slightly and pull down the lower eyelid to form a pouch. 3. Hold the dropper above the eye and instill the prescribed number of drops. 4. Close the eye gently and apply gentle pressure to the inner corner of the eye for 1 to 2 minutes to prevent the medication from draining away. 5. Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects: o Temporary eye discomfort, such as stinging or burning sensations. o Blurred vision. o Headache. • Visual disturbances. • Serious Side Effects: o Although rare, systemic absorption may lead to increased blood pressure, headache, or dizziness. • Precautions: o Consult your doctor if you are pregnant or breastfeeding, as the safety of Pilocarpine Nitrate 4% during these periods is not well-established. o Use with caution if you have a history of retinal diseases or other eye conditions. o Avoid driving or operating machinery if you experience blurred vision or visual disturbances.

Paricar (Pilocarpine Nitrate 2% Eye Drops) is a miotic ophthalmic solution primarily used to manage certain eye conditions by reducing intraocular pressure. ________________________________________ 🔍 Uses 1. Treatment of Glaucoma and Ocular Hypertension Pilocarpine Nitrate 2% is employed to lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It facilitates the drainage of aqueous humor from the eye, thereby reducing IOP and helping prevent vision loss and nerve damage. 2. Management of Acute Angle-Closure Glaucoma In acute angle-closure glaucoma, Pilocarpine Nitrate 2% may be used to constrict the pupil, facilitating the opening of the angle between the iris and cornea, which helps in reducing IOP. 3. Induction of Miosis Pilocarpine Nitrate 2% is utilized to induce miosis (pupil constriction) during certain eye surgeries or to reverse the effects of drugs used to dilate the pupil during eye examinations. ________________________________________ 💧 Dosage and Administration • General Dosage: Instill one drop into the affected eye(s) 1 to 4 times daily, as directed by your healthcare provider. • Application Method: 1. Wash your hands thoroughly before use. 2. Tilt your head back slightly and pull down the lower eyelid to form a pouch. 3. Hold the dropper above the eye and instill the prescribed number of drops. 4. Close the eye gently and apply gentle pressure to the inner corner of the eye for 1 to 2 minutes to prevent the medication from draining away. 5. Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects: o Temporary eye discomfort, such as stinging or burning sensations. o Blurred vision. o Headache. • Visual disturbances. • Serious Side Effects: o Although rare, systemic absorption may lead to increased blood pressure, headache, or dizziness. • Precautions: o Consult your doctor if you are pregnant or breastfeeding, as the safety of Pilocarpine Nitrate 2% during these periods is not well-established. o Use with caution if you have a history of retinal diseases or other eye conditions. o Avoid driving or operating machinery if you experience blurred vision or visual disturbances.

7 PM Eye Drop is a medicine used to reduce pressure in the eyes in people with glaucoma and ocular hypertension (high pressure in the eye). If the pressure in your eye is too high it can damage your sight, potentially leading to blindness. It works by helping fluid flow from inside the eye into the blood. 7 PM Eye Drop is suitable for adults and children and can be used by itself or in combination with other eye medicines to reduce pressure. Follow the instructions given by your doctor and use this medicine regularly to get the most benefit. If you stop using it, pressure in the eye could increase and damage your sight. Never use a bottle if the seal is broken before you use it for the first time. If you wear contact lenses, make sure you remove them before instilling and wait for at least 15 minutes before putting them back. The most common side effects include eyelashes changes, eye pain and sensitivity to light. It may also cause blurred vision, dryness in the eye, a gradual change in color of the eye, and other rare effects. If you get any side effects, talk to your doctor. Your doctor may be able to tell you ways of reducing or preventing some side effects or suggest another treatment. If your vision is blurred or you have other changes in sight for a time, do not drive until your vision is clear. This is usually a short-term side effect. Do not use this medicine if you are pregnant or trying to become pregnant, or if you are breastfeeding.

7.30 PM Eye Drop is a medicine used to reduce pressure in the eyes in people with glaucoma and ocular hypertension (high pressure in the eye). If the pressure in your eye is too high it can damage your sight, potentially leading to blindness. It works by helping fluid flow from inside the eye into the blood. 7.30 PM Eye Drop is suitable for adults and children and can be used by itself or in combination with other eye medicines to reduce pressure. Follow the instructions given by your doctor and use this medicine regularly to get the most benefit. If you stop using it, pressure in the eye could increase and damage your sight. Never use a bottle if the seal is broken before you use it for the first time. If you wear contact lenses, make sure you remove them before instilling and wait for at least 15 minutes before putting them back. The most common side effects include eyelashes changes, eye pain and sensitivity to light. It may also cause blurred vision, dryness in the eye, a gradual change in color of the eye, and other rare effects. If you get any side effects, talk to your doctor. Your doctor may be able to tell you ways of reducing or preventing some side effects or suggest another treatment. If your vision is blurred or you have other changes in sight for a time, do not drive until your vision is clear. This is usually a short-term side effect. Do not use this medicine if you are pregnant or trying to become pregnant, or if you are breastfeeding.

Nitrocin 5ML Injection Marketer Samarth Life Sciences Pvt Ltd SALT COMPOSITION Nitroglycerin (5mg/ml) Salt Synonyms Glyceryl Trinitrate Storage Store below 30°C Uses of Nitrocin Injection Angina (heart-related chest pain) Heart Failure Treatment of Hypertension (high blood pressure) Coronary artery disease Hypertensive emergency Anal fissure Product introduction Nitrocin 5mg Injection is used to treat and prevent heart-related chest pain (angina) and hypertension (high blood pressure) during surgery. This medicine works by relaxing and widening blood vessels so blood can flow more easily to the heart. It has a very short-lived effect. Nitrocin 5mg Injection is given as an injection under the supervision of a doctor with careful blood pressure monitoring. This is given as a continuous infusion into a vein and should not be stopped abruptly. It should not be mixed with any other medication of any kind. The most common side effect of Nitrocin 5mg Injection is a headache which may be severe. This can sometimes be helped by drinking plenty of fluids and avoiding alcohol. You may also experience lightheadedness, which could increase your risk of having a fall. There are other, rarer side effects, some of them serious. Ask your doctor and read the leaflet which comes with the medicine to make sure you are keeping safe. Do not use Nitrocin 5mg Injection if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), or erectile dysfunction; or if you have anemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. It is best not to drink alcohol with this medicine as it increases some of the side effects. If you are affected by dizziness, avoid driving. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine. Benefits of Nitrocin Injection In Treatment of Hypertension (high blood pressure) Nitrocin 5mg Injection is used to treat hypertension in hypertensive emergencies. It rapidly dilates (widens) the blood vessels. This rapid vasodilation helps reduce blood pressure levels, relieving the strain on the heart and improving blood flow to vital organs. It is typically used in critical situations where immediate blood pressure reduction is necessary, such as severe high blood pressure that can lead to organ damage or other life-threatening complications. Side effects of Nitrocin Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Nitrocin Blurred vision Decreased blood pressure Dizziness Headache Increased heart rate Lightheadedness Paresthesia (tingling or pricking sensation) How to use Nitrocin Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Nitrocin Injection works Nitrocin 5mg Injection is a nitrate. It works by improving blood supply to heart and relaxing the blood vessels which decreases the oxygen demand of the heart and reduces its workload, thereby preventing/treating attacks of angina (chest pain). Relaxation of blood vessels lowers blood pressure. Safety advice warnings Alcohol UNSAFE Consuming alcohol while taking Nitrocin 5mg Injection may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction). warnings Pregnancy SAFE IF PRESCRIBED Nitrocin 5mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. warnings Breast feeding SAFE IF PRESCRIBED Nitrocin 5mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. warnings Driving UNSAFE Nitrocin 5mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. warnings Kidney SAFE IF PRESCRIBED Nitrocin 5mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nitrocin 5mg Injection may not be needed in these patients. Please consult your doctor. warnings Liver CONSULT YOUR DOCTOR There is limited information available on the use of Nitrocin 5mg Injection in patients with liver disease. Please consult your doctor.

Dorzopar Eye Drops containing Dorzolamide 2% are primarily used to lower intraocular pressure (IOP) in individuals with glaucoma or ocular hypertension (high eye pressure). Here's a detailed breakdown of its uses: 🔹 Primary Uses Open-Angle Glaucoma Dorzolamide is a carbonic anhydrase inhibitor that helps reduce the production of aqueous humor (the fluid inside the eye). By decreasing the amount of fluid produced, it lowers the intraocular pressure (IOP), which is important in treating open-angle glaucoma. Glaucoma is a condition where high eye pressure can damage the optic nerve and lead to vision loss. Ocular Hypertension Dorzopar is also used for the treatment of ocular hypertension, a condition in which the eye pressure is elevated but glaucoma has not yet developed. Lowering eye pressure helps prevent the progression to glaucoma. 🔹 How It Works Dorzolamide works by inhibiting the carbonic anhydrase enzyme in the eye. This enzyme is involved in the production of aqueous humor. By blocking this enzyme, Dorzolamide reduces the amount of fluid produced inside the eye, which in turn lowers the eye pressure. ⚠️ Common Side Effects Eye irritation, burning, or stinging upon application Blurred vision (temporary) Redness in the eyes or foreign body sensation Dry eyes or increased tear production Headaches or dizziness (in some cases) Taste disturbance (a bitter taste in the mouth) 🔹 Usage Tips Dosage: Typically, 1 drop in each affected eye, twice daily (morning and evening), or as prescribed by your healthcare provider. Application Instructions: Wash your hands thoroughly before applying the drops. Tilt your head back slightly and pull down your lower eyelid to form a small pocket. Place one drop in the pocket without touching the dropper tip to your eye. Gently close your eye and blink a few times to help spread the medication. If using other eye medications, wait 5–10 minutes between applications. Contact Lenses: Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them. 🔹 Precautions Kidney or Liver Problems: Since Dorzolamide is metabolized in the body, it should be used with caution in individuals with kidney or liver issues. Pregnancy and Breastfeeding: Consult your doctor before using this medication if you are pregnant or breastfeeding, as the safety of Dorzolamide during pregnancy or while breastfeeding has not been fully established. Eye Infections: Be cautious if you have an eye infection, as Dorzolamide may not be suitable for some active infections. Systemic Effects: While Dorzolamide is generally applied locally to the eye, some systemic absorption may occur, leading to side effects like metabolic acidosis (rare). It should be used cautiously in patients with a history of diabetes, kidney disease, or respiratory problems.

INTRODUCTION ABALAM 600/300 is a combination of Abacavir and Lamivudine which belongs to the group of medicines called Anti-viral agents. It is used in the management of HIV infection in adults, adolescents and in children (weighing above 25 kgs). HIV (human immunodeficiency virus) infection is a viral infection that damages our immune system and weakens our body’s ability to fight against various infections. Both abacavir and lamivudine are nucleoside reverse transcriptase inhibitors. They work by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. This prevents further multiplication of viral cells within the body. Also, they can improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. ABALAM 600/300 cannot not manage HIV infection completely. It can reduce only the number of viral cells present in the body and maintains them at a lower level. During management with ABALAM 600/300 your doctor will closely monitor your body weight, blood cholesterol levels and blood sugar levels to reduce the risk of unwanted side effects. Do not take ABALAM 600/300 if you are allergic to abacavir or lamivudine. Before taking ABALAM 600/300 inform your doctor if you have diabetes or any liver (hepatitis C or B infection), kidney or heart problems. If you are already taking ABALAM 600/300 to manage hepatitis B or C infection, do not stop taking it without consulting your doctor. Even if you take ABALAM 600/300, it is important for you to follow certain measures to prevent the spread of infections to the other people (such as avoid having unprotected sexual intercourse or sharing needles or personal items like toothbrush, razors etc with other people). ABALAM 600/300 is not recommended for use in pregnant or breastfeeding women. The most common side effects of taking ABALAM 600/300 are difficulty in sleeping, increased signs of infections, nausea, stomach pain, headache, or dizziness. Consult your doctor if any of these side effects worsens. Also inform your doctor immediately if you experience severe fever with extreme tiredness, sudden changes in body weight or severe stomach pain along with dark urine after taking ABALAM 600/300. USES OF ABALAM 600/300 Manages HIV infection in adults, adolescents and in children (weighing above 25 kgs) HOW ABALAM 600/300 WORKS ABALAM 600/300 is an anti-retroviral medicine. It controls the multiplication of viral cell within the body, by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. It can also improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. DIRECTIONS FOR USE Take ABALAM 600/300 as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. ABALAM 600/300 can be taken with or without meals. Your doctor will decide the correct dose and for how long ABALAM 600/300 must be taken depending upon your age, body weight and severity of the infection. Do not stop taking ABALAM 600/300 without consulting your doctor as it may reduce its effectiveness. SIDE EFFECTS OF ABALAM 600/300 COMMON difficulty in sleeping feeling depressed headache, tiredness, dizziness nausea, diarrhoea fever, skin rash stomach pain loss of appetite irritated or runny nose hair loss UNCOMMON decrease in RBC, WBC, and platelets RARE Stop taking ABALAM 600/300 and contact your doctor immediately if you experience any of the following side effects: signs of allergic reactions (such as skin rash, fever, accompanied with sore throat, cough, nausea, vomiting, stomach pain, diarrhea, tiredness, joint pain, muscle pain, swelling of the neck, difficulty in breathing, mouth ulcers, occasional headaches, inflammation of the eye, low blood pressure, sense of tingling or numbness of hands or feet) pure red cell aplasia (failure of bone marrow to produce new red blood cells) signs of infections (such as fever, headache, stomach-ache, breathing difficulty) signs of auto-immune disorders (such as rapid or irregular heartbeat, tremor, hyperactivity, general weakness) signs of osteonecrosis (death of bone cells causing joint stiffness, pain in the hip, knee or shoulder and difficulty in moving) signs of liver problems (such as yellowing of the skin and whites of the eye, dark urine, light-coloured stools, loss of appetite, nausea, pain, tenderness on the right side of stomach) heart attack changes in body fat (such as increase fat in the shoulder and neck (buffalo hump), breast, and in the middle body or fat loss from the legs, arms, or face)

Marketer Khandelwal Laboratories Pvt Ltd SALT COMPOSITION Erlotinib (150mg) Storage Store below 30°C Uses of Erlotaz Tablet Pancreatic cancer Small cell lung cancer Liver cancer Kidney cancer Thyroid cancer Blood cancer (Chronic myeloid leukaemia) Gastrointestinal stromal tumour Cancer of colon and rectum Non-small cell lung cancer Soft tissue sarcoma Chronic idiopathic myelofibrosis Breast cancer Product introduction Erlotaz 150 Tablet is used in the treatment of non-small cell lung cancer and pancreatic cancer. Erlotaz 150 Tablet should be taken on an empty stomach or should be taken one hour before or 2 hour after meal. You should continue to take it as long as your doctor advises it. The duration of treatment varies according to your needs and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include nausea, vomiting, fatigue, rash, and weight loss. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. It makes you sensitive towards sunlight, hence wear protective clothing or use sunscreen while going out. In case you develop ulceration in mouth, changes in your vision, or breathing difficulties than it is better to inform the doctor. Your doctor may advise for regular monitoring of liver function while you are taking this medicine. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. It is advised to quit smoking while taking this medicine as it can affect the working of the medicine. If you have to take an antacid or any other medicine, take it at a gap of at least 2 hours after taking the cancer medicine. Side effects of Erlotaz Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Erlotaz Abdominal pain Bone pain Breathlessness Constipation Cough Diarrhea Fatigue Fever Infection Muscle pain Nausea Rash Stomatitis (Inflammation of the mouth) Vomiting Weight loss How to use Erlotaz Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Erlotaz 150 Tablet is to be taken empty stomach. How Erlotaz Tablet works Erlotaz 150 Tablet is an anti-cancer medication. Epidermal growth factor receptors (EGFR) are expressed on the lung cancer cell surfaces that modulate their growth. This medicine works by binding the chemical messenger, EGFR, hence, inhibits the cancer signaling pathways mediated by EGFR. This is how it restricts further growth of the cancer cells. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Erlotaz 150 Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Erlotaz 150 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Erlotaz 150 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. warnings Driving CONSULT YOUR DOCTOR It is not known whether Erlotaz 150 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. warnings Kidney SAFE IF PRESCRIBED Erlotaz 150 Tablet is safe to use in patients with kidney disease. No dose adjustment of Erlotaz 150 Tablet is recommended. Use of this medicine is not advised in patients with severe kidney disease.

Marketer Khandelwal Laboratories Pvt Ltd SALT COMPOSITION Erlotinib (150mg) Storage Store below 30°C Uses of Erlotaz Tablet Pancreatic cancer Small cell lung cancer Liver cancer Kidney cancer Thyroid cancer Blood cancer (Chronic myeloid leukaemia) Gastrointestinal stromal tumour Cancer of colon and rectum Non-small cell lung cancer Soft tissue sarcoma Chronic idiopathic myelofibrosis Breast cancer Product introduction Erlotaz 150 Tablet is used in the treatment of non-small cell lung cancer and pancreatic cancer. Erlotaz 150 Tablet should be taken on an empty stomach or should be taken one hour before or 2 hour after meal. You should continue to take it as long as your doctor advises it. The duration of treatment varies according to your needs and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include nausea, vomiting, fatigue, rash, and weight loss. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. It makes you sensitive towards sunlight, hence wear protective clothing or use sunscreen while going out. In case you develop ulceration in mouth, changes in your vision, or breathing difficulties than it is better to inform the doctor. Your doctor may advise for regular monitoring of liver function while you are taking this medicine. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. It is advised to quit smoking while taking this medicine as it can affect the working of the medicine. If you have to take an antacid or any other medicine, take it at a gap of at least 2 hours after taking the cancer medicine. Side effects of Erlotaz Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Erlotaz Abdominal pain Bone pain Breathlessness Constipation Cough Diarrhea Fatigue Fever Infection Muscle pain Nausea Rash Stomatitis (Inflammation of the mouth) Vomiting Weight loss How to use Erlotaz Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Erlotaz 150 Tablet is to be taken empty stomach. How Erlotaz Tablet works Erlotaz 150 Tablet is an anti-cancer medication. Epidermal growth factor receptors (EGFR) are expressed on the lung cancer cell surfaces that modulate their growth. This medicine works by binding the chemical messenger, EGFR, hence, inhibits the cancer signaling pathways mediated by EGFR. This is how it restricts further growth of the cancer cells. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Erlotaz 150 Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Erlotaz 150 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Erlotaz 150 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. warnings Driving CONSULT YOUR DOCTOR It is not known whether Erlotaz 150 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. warnings Kidney SAFE IF PRESCRIBED Erlotaz 150 Tablet is safe to use in patients with kidney disease. No dose adjustment of Erlotaz 150 Tablet is recommended. Use of this medicine is not advised in patients with severe kidney disease. warnings Liver CAUTION Erlotaz 150 Tablet should be used with caution in patients with liver disease. Dose adjustment of Erlotaz 150 Tablet may be needed. Please consult your doctor.