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'lead chelation'

Items tagged with 'lead chelation'

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General Medicine

Disodium Edetate Injection (also written as EDTA Disodium or Disodium EDTA) is a chelating agent with very limited and specific medical uses due to the risk of serious side effects. 🔹 Approved Medical Uses of Disodium Edetate Injection: 🔻 Treatment of Severe Hypercalcemia Primary use: Treats life-threatening high calcium levels in the blood. It binds to excess calcium ions and helps remove them from the body via the kidneys. 💊 Digitalis (Digoxin) Toxicity (rare/adjunct) In cases of digoxin overdose, disodium EDTA may be used to lower calcium, which worsens digoxin's toxic effects. ⚠️ NOT for Lead Poisoning ⚠️ Very important: Disodium EDTA is not used for lead poisoning. It can dangerously lower blood calcium and cause fatal hypocalcemia. The safe version for lead chelation is Calcium Disodium EDTA (CaNa₂EDTA). 💉 How It’s Given: Intravenously (IV) and must be administered slowly. Requires monitoring of calcium and kidney function. ⚠️ Risks and Side Effects: Severe hypocalcemia (can cause seizures, cardiac arrhythmias, or death). Kidney damage Nausea, vomiting, headache Blood pressure drops Injection site irritation 🚫 Not Approved For: “Detox” or anti-aging therapy Cardiovascular or atherosclerosis treatment (not FDA-approved and unsafe) ✅ Summary: Condition Use of Disodium EDTA Severe Hypercalcemia ✅ Yes Digoxin (digitalis) toxicity ⚠️ Rare, supportive Lead or heavy metal poisoning ❌ NO (use CaNa₂EDTA) Detox / cosmetic use ❌ Not approved/safe

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General Medicine

Disodium EDTA Injection (Ethylenediaminetetraacetic acid, disodium salt) is a chelating agent, similar to calcium disodium EDTA, but with different uses, safety profile, and risks. It’s much less commonly used today due to safety concerns and has narrower indications. 🔹 Main Uses of Disodium EDTA Injection: 🦙 Hypercalcemia (High Blood Calcium Levels) It can be used in emergency treatment of severe hypercalcemia, especially when rapid calcium reduction is required. It works by binding free calcium ions in the blood. 🫀 Digitalis Toxicity (rare use) Sometimes used to manage digoxin toxicity by lowering calcium levels, as excess calcium can worsen digoxin effects. 🧪 Experimental or Unapproved Use: Chelation therapy for atherosclerosis (plaque buildup in arteries): Previously promoted in 'alternative' medicine as a treatment for heart disease. ⚠️ Not FDA-approved for cardiovascular use due to risk of severe side effects including death. ⚠️ Important Warnings & Safety Concerns: Disodium EDTA has been associated with fatal hypocalcemia (low calcium levels) when misused. Because of this, it is generally not used for lead poisoning—Calcium Disodium EDTA (CaNa₂EDTA) is the preferred and safer agent. It requires hospital setting administration with continuous monitoring. 💉 How It’s Given: Administered via IV infusion. Given slowly to prevent rapid electrolyte shifts and heart complications. 🚫 Not Used For: Lead poisoning — too dangerous due to calcium depletion. General detox — not approved or supported by scientific evidence.

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General Medicine

Calcium Edetate Injection (also known as Calcium Disodium EDTA) is a chelating agent used mainly to treat heavy metal poisoning, particularly lead poisoning. 🔹 Primary Uses of Calcium Edetate Injection: 🧪 Lead Poisoning (Plumbism) Main use: binds to lead in the bloodstream and helps eliminate it through the urine. Often used in moderate to severe cases, especially in children and industrial exposure. 🌡️ Other Heavy Metal Toxicity (off-label or less common) May also be used (less commonly) for: Cadmium Zinc (in overload situations) Not used for mercury or arsenic—other chelators like dimercaprol or DMSA are preferred there. 🔄 Diagnostic Use (EDTA lead mobilization test) Sometimes used to test the body's lead burden by observing how much lead is excreted after administration. 💉 How It Works: Chelation therapy: The EDTA binds to heavy metal ions in the blood. The resulting complex is water-soluble and excreted through the kidneys. 💉 Administration: IV (intravenous) or IM (intramuscular) injection. Usually given over several days, depending on lead levels and patient condition. Often used alongside hydration therapy to protect the kidneys. ⚠️ Precautions & Side Effects: Kidney function must be closely monitored — chelation can be hard on the kidneys. Electrolyte imbalances (e.g., calcium, zinc depletion) may occur. Possible side effects: Fever, chills Nausea, vomiting Injection site pain Low blood pressure (rare but serious) ❗ Important Notes: Not the same as disodium EDTA, which is more toxic and not approved for lead poisoning. Must be used under strict medical supervision, especially in children.

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Drop Shipping

Pharmacy Dropshipping in Australia – Wholesale Medicine Exporter from India Ernest Pharmaceuticals Pvt. Ltd. is a leading name in pharmacy dropshipping services in Australia. With over a decade of global experience, we help pharmacies, clinics, and online medical retailers in Australia access WHO-GMP certified Indian medicines directly through our efficient dropshipping model. Why Choose Ernest Pharmaceuticals for Dropshipping to Australia? ✅ No Inventory Hassles – medicines delivered directly to your customers. ✅ WHO-GMP Certified Products meeting global safety and quality standards. ✅ Competitive Pricing for pharmacies and bulk buyers. ✅ Private Label Support for custom branding. ✅ Safe & Reliable International Shipping to all major Australian cities. Products We Supply: Erectile Dysfunction Medicines (Sildenafil, Tadalafil, Vardenafil) Cancer & Oncology Treatments Injectables & IV Infusions Skin & Dermatology Products Nutraceuticals & General Wellness Steroids & Hormone Therapy Medicines Major Cities in Australia We Cover: 📍 Sydney | 📍 Melbourne | 📍 Brisbane | 📍 Perth | 📍 Adelaide | 📍 Gold Coast | 📍 Canberra | 📍 Hobart | 📍 Darwin About Ernest Pharmaceuticals We are one of India’s most trusted medicine exporters and dropshipping service providers, serving 80+ countries worldwide. Our commitment is to provide affordable, reliable, and quality medicines to healthcare professionals and pharmacies across Australia. 📧 Email: exports@ernestpharmaceuticals.com 📲 WhatsApp: +91 94054 76170 🌐 Website: www.ernestpharmaceuticals.com | www.ernestimpex.com 👉 Message us on WhatsApp today to get the best pharmacy dropshipping deals for Australia.

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Drop Shipping

Pharma Drop Shipper India to USA – Wholesale Medicine Exporter If you are looking for a reliable pharma drop shipper from India to USA, Ernest Pharmaceuticals Pvt. Ltd. is your trusted partner. With over 10 years of global experience, we specialize in medicine dropshipping, bulk exports, and wholesale supply of WHO-GMP certified pharmaceuticals to pharmacies, distributors, hospitals, and online clinics across the United States. Why Choose Ernest Pharmaceuticals for USA Pharma Supply? ✅ WHO-GMP Certified Medicines ensuring international quality. ✅ Wholesale & Bulk Supply at competitive pricing. ✅ Dropshipping to USA Pharmacies & Clinics – save inventory & storage costs. ✅ Private Label & Branding Support available. ✅ Secure & Discreet Delivery with international trust. Our Pharma Dropshipping Service to USA We simplify the supply chain for American pharmacies, clinics, and online retailers. With dropshipping, you don’t need to stock medicines. Place your order and we take care of packaging and fast, reliable delivery to cities across the USA. Medicines We Export: Erectile Dysfunction Medicines (Sildenafil, Tadalafil, Vardenafil) Oncology & Cancer Treatment Medicines Injectables & IV Infusions Skin Care & Dermatology Treatments Nutraceuticals & Wellness Products Hormone & Steroid Medicines Major USA Cities We Cover: 📍 New York | 📍 Los Angeles | 📍 Chicago | 📍 Houston | 📍 Phoenix | 📍 Philadelphia | 📍 Dallas | 📍 San Francisco | 📍 Miami | 📍 Boston | 📍 Atlanta | 📍 Seattle | 📍 Washington D.C. About Ernest Pharmaceuticals Ernest Pharmaceuticals Pvt. Ltd. is one of the leading pharma exporters in India, supplying to 80+ countries worldwide. With a reputation for quality, affordability, and reliability, we are the preferred choice of pharmacies and distributors in the USA. 📧 Email: exports@ernestpharmaceuticals.com 📲 WhatsApp: +91 94054 76170 🌐 Website: www.ernestpharmaceuticals.com | www.ernestimpex.com 👉 Contact us on WhatsApp today to get the best wholesale deals on Indian medicines delivered to the USA.

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Cats and Dogs

Chronic kidney disease is a common kidney disorder in adult and aged dogs and cats. The gradual decline in kidney function leads to an accumulation of toxins normally cleared by the kidneys, resulting in uremia. Renodis is a combination of prebiotic and probiotic bacteria that helps to normalize gut dysbiosis, a condition that happens when there is an imbalance between good and bad bacteria in the gut. Renodis contains 3 live therapeutic bacteria that have been validated in patients with kidney disease. Renodis performs natural enteric dialysis by helping to restore the balance of bacteria in the gut. It can further help to slow down uremic toxin build-up in patients with renal insufficiency

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Eye Care

Tropind Plus is a combination ophthalmic solution containing Tropicamide 0.8% and Phenylephrine 5%. This formulation is primarily used for both diagnostic and therapeutic purposes in ophthalmology. 🩺 Primary Uses of Tropind Plus 1. Pupillary Dilation (Mydriasis): The combination of Tropicamide and Phenylephrine effectively dilates the pupil, allowing eye care professionals to conduct thorough examinations of the retina, optic nerve, and other internal structures. 2. Cycloplegia: Tropicamide paralyzes the ciliary muscle, preventing accommodation (focusing), which is useful in refractive error assessments. 3. Uveitis Management: In cases of uveitis, Tropind Plus helps alleviate pain and prevents further spasms of the eye muscles. 4. Preoperative Preparation: Before surgeries like cataract extraction or retinal procedures, dilating the pupil is essential for clear visualization of the posterior segment. 5. Retinal Imaging: Facilitates procedures such as fundus photography and optical coherence tomography (OCT) by ensuring adequate pupil dilation. ⚙️ How It Works • Tropicamide is a parasympatholytic agent that inhibits the contraction of the circular muscle and paralyzes the ciliary muscle, leading to pupil dilation and cycloplegia. Phenylephrine is a sympathomimetic drug that causes contraction of the radial muscle of the iris, contributing to pupil dilation. Together, these agents produce rapid and effective dilation of the pupil, facilitating detailed eye examinations and procedures. ⚠️ Side Effects Common side effects may include: • Eye pain or stinging • Blurred vision • Sensitivity to light (photophobia) • Allergic reactions These effects are typically temporary and resolve shortly after the examination. 🧪 Safety and Precautions • Driving and Operating Machinery: Avoid activities that require clear vision, such as driving, immediately after application, as the solution can cause temporary blurred vision. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or while breastfeeding, as safety data may be limited. • Drug Interactions: Be cautious when using Tropind Plus with certain medications, especially monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants, as interactions may occur.

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Eye Care

Biotrav (Travoprost) Ophthalmic Solution Biotrav is a prescription eye drop containing travoprost, a prostaglandin analog used to lower intraocular pressure (IOP) in individuals with open-angle glaucoma or ocular hypertension. ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common type of glaucoma characterized by gradual loss of vision due to increased IOP. • Ocular Hypertension: Elevated IOP without optic nerve damage, which can lead to glaucoma if untreated. ________________________________________ 💊 Dosage and Administration • Recommended Dosage: Instill one drop into the affected eye(s) once daily in the evening. • Application Tips: o Wash hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to travoprost or any component of the formulation. o Active or suspected ocular infections. o History of hypersensitivity to prostaglandin analogs. • Cautions: o Use with caution in patients with a history of uveitis, macular edema, or retinal vein occlusion. o May cause changes in eye color, eyelash growth, and skin pigmentation around the eyes. o Consult a healthcare provider before use if pregnant, planning to become pregnant, or breastfeeding. ________________________________________ 🧪 Mechanism of Action Travoprost works by increasing the outflow of aqueous humor through the trabecular meshwork and uveoscleral pathways, thereby reducing IOP. This helps prevent damage to the optic nerve and loss of vision associated with glaucoma and ocular hypertension.

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