Tobi-D (Tobramycin with Dexamethasone) Eye Drops is a prescription ophthalmic solution combining an antibiotic and a corticosteroid to treat specific bacterial eye infections accompanied by inflammation. ________________________________________ ✅ Primary Uses Tobi-D is primarily used for: • Bacterial Conjunctivitis: Infection of the conjunctiva (the membrane covering the white part of the eye and the inner surface of the eyelids). • Keratitis: Infection of the cornea. • Post-surgical Infections: Prophylactic treatment or management of infections following eye surgeries. It addresses both the infection and the inflammation associated with these conditions. ________________________________________ 💊 Dosage and Administration • Standard Dosage: Instill 1–2 drops into the affected eye(s) every 4–6 hours, or as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Contraindications and Cautions • Contraindications: o Hypersensitivity to tobramycin, dexamethasone, or any component of the formulation. o Active viral infections of the eye, such as herpes simplex keratitis. o Untreated fungal or mycobacterial infections of the eye. • Cautions: o Use with caution in patients with a history of glaucoma, as corticosteroids can increase intraocular pressure. o Prolonged use may lead to cataract formation or secondary ocular infections. o Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. ________________________________________ 🧪 Mechanism of Action • Tobramycin: An aminoglycoside antibiotic that inhibits bacterial protein synthesis, leading to bacterial cell death. • Dexamethasone: A corticosteroid that reduces inflammation by inhibiting the release of inflammatory mediators. Together, these components address both the infection and the inflammation associated with certain eye conditions.

Tobi-F (Tobramycin Sulphate and Fluorometholone) Ophthalmic Solution is a prescription eye drop that combines an antibiotic and a corticosteroid to treat specific eye conditions. ________________________________________ ✅ Primary Uses Tobi-F is primarily used to manage inflammatory eye conditions where a steroid is indicated and where there is a risk of or existing superficial bacterial infection. The combination of tobramycin and fluorometholone addresses both the infection and the inflammation. ________________________________________ 💊 Dosage and Administration • Standard Dosage: Instill 1–2 drops into the affected eye(s) every 4–6 hours, or as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Contraindications and Cautions • Contraindications: o Hypersensitivity to tobramycin, fluorometholone, or any component of the formulation. o Active viral infections of the eye, such as herpes simplex keratitis. • Untreated fungal or mycobacterial infections of the eye. • Cautions: o Use with caution in patients with a history of glaucoma, as corticosteroids can increase intraocular pressure. o Prolonged use may lead to cataract formation or secondary ocular infections. o Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.

Marketer Steadfast Medishield Pvt Ltd SALT COMPOSITION Valganciclovir (450mg) Storage Store below 30°C Uses of Valstead Tablet Treatment of Cytomegalovirus Infection Herpes labialis Genital herpes infection Chickenpox Herpes Simplex Virus Infections Eye infections by Herpes simplex virus Chronic hepatitis C virus (HCV) infection Product introduction Valstead 450mg Tablet is used to treat cytomegalovirus (CMV) infection of the retina (retinitis) in adult patients with acquired immunodeficiency syndrome (AIDS). It is also used for the prevention of CMV infection in patients who have received an organ transplant from a CMV-infected donor. Valstead 450mg Tablet should be taken in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. It should be taken with food. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. You should drink plenty of water while on treatment with this medicine as it helps to prevent dehydration and kidney damage. It may lead to a few common side effects like fever, diarrhea, vomiting, anemia, low white blood cell, and low platelet level. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding. Benefits of Valstead Tablet In Treatment of Cytomegalovirus Infection Cytomegalovirus infection is a common virus infection which may have no symptoms at all or may have symptoms like fever and fatigue. Severe infection may show symptoms involving the eyes, brain, or other internal organs. This virus is spread through sexual and nonsexual contact with body secretions in people who are immunocompromised or those who have undergone any transplant. Valstead 450mg Tablet helps to prevent multiplication of the infection causing virus and treats the infection. Keep taking it in the dose and duration prescribed by the doctor to get maximum benefit. Side effects of Valstead Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Valstead Diarrhea Fever Vomiting Anemia (low number of red blood cells) Decreased white blood cell count Low blood platelets Insomnia (difficulty in sleeping) Tremors How to use Valstead Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Valstead 450mg Tablet is to be taken with food. How Valstead Tablet works Valstead 450mg Tablet is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Clocivir 500 Injection is an intravenous formulation containing Acyclovir 500 mg, manufactured by American Remedies. It is primarily used to treat severe viral infections caused by herpes viruses. ________________________________________ 🩺 Uses of Clocivir 500 Injection Clocivir 500 Injection is indicated for: • Herpes Simplex Infections in Immunocompromised Patients: Including severe primary or non-primary genital herpes. • Herpes Simplex Encephalitis: A serious brain infection caused by the herpes simplex virus. • Neonatal Herpes Simplex Virus Infection: In newborns. • Varicella-Zoster Infections in Immunocompromised Patients: Such as severe cases of chickenpox or shingles. • Severe Herpes Zoster (Shingles): In immunocompetent patients with very severe acute local or systemic manifestations. ________________________________________ 💊 Mechanism of Action Acyclovir, the active ingredient in Clocivir, is a synthetic purine nucleoside analogue. It exerts its antiviral effects by inhibiting viral DNA synthesis, thereby preventing the replication of herpes viruses. Acyclovir is converted to its active form, Acyclovir Triphosphate, within infected cells, which then interferes with viral DNA polymerase. ________________________________________ ⚠️ Precautions • Administration: Clocivir 500 Injection should be administered by a healthcare professional through slow intravenous infusion over a 1-hour period to minimize the risk of kidney damage. • Hydration: Adequate hydration is essential during treatment to prevent dehydration and kidney damage. • Kidney Function: Use with caution in patients with pre-existing kidney conditions. • Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Clocivir 250 Injection is an intravenous formulation containing Acyclovir 250 mg, manufactured by American Remedies. It is primarily used to treat severe viral infections caused by herpes viruses. ________________________________________ 🩺 Uses of Clocivir 250 Injection Clocivir 250 Injection is indicated for: • Herpes Simplex Virus Infections: Including severe cases in immunocompromised patients. • Genital Herpes: Especially primary or non-primary severe cases. • Herpes Zoster (Shingles): In immunocompetent patients with severe manifestations. • Chickenpox (Varicella Zoster Virus Infection): Particularly in immunocompromised individuals. • Herpes Simplex Encephalitis: A severe brain infection caused by the herpes simplex virus. ________________________________________ 💊 Mechanism of Action Acyclovir, the active ingredient in Clocivir, is a synthetic purine nucleoside analogue. It exerts its antiviral effects by inhibiting viral DNA synthesis, thereby preventing the replication of herpes viruses. Acyclovir is converted to its active form, Acyclovir Triphosphate, within infected cells, which then interferes with viral DNA polymerase . ________________________________________ ⚠️ Precautions • Administration: Clocivir 250 Injection should be administered by a healthcare professional through slow intravenous infusion over a 1-hour period to minimize the risk of kidney damage . • Hydration: Adequate hydration is essential during treatment to prevent dehydration and kidney damage. • Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to conceive, or breastfeeding. • Drug Interactions: Inform your healthcare provider about all other medications you are taking to avoid potential interactions.

Tobi (Tobramycin Ophthalmic Solution) is a prescription antibiotic eye drop used to treat bacterial infections of the eye. It contains 0.3% tobramycin, a broad-spectrum aminoglycoside antibiotic effective against various gram-positive and gram-negative bacteria. ________________________________________ ✅ Primary Uses • Bacterial Conjunctivitis: Infection of the conjunctiva (the membrane covering the white part of the eye and the inner surface of the eyelids). • Blepharitis: Inflammation of the eyelid margins, often associated with bacterial infection. • Keratitis: Infection of the cornea. • Post-surgical Infections: Prophylactic treatment or management of infections following eye surgeries. Tobramycin ophthalmic solution is typically used alone or in combination with other medications, depending on the severity and type of infection . ________________________________________ 💊 Dosage and Administration • Standard Dosage: Instill 1–2 drops into the affected eye every 4 hours during the day. • Severe Infections: In some cases, the dosage may be increased to 2 drops every hour, as directed by a healthcare provider . • Application Tips: o Wash hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If wearing contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: • Hypersensitivity to tobramycin or any component of the formulation . • Cautions: o Use with caution in pregnant or breastfeeding women; consult a healthcare provider before use . o Prolonged use may lead to the development of resistant bacteria. o Should not be used in children without medical supervision. ________________________________________

FZ-3 Eye-Ear Drops containing Fluconazole are primarily used to treat fungal infections of the eyes and ears. Fluconazole is an antifungal medication that works by inhibiting the growth of fungi. 🔹 Primary Uses Fungal Eye Infections (Ophthalmic Fungal Infections) Fluconazole in eye drop form is used to treat fungal infections of the eye, such as fungal keratitis or endophthalmitis, which can cause inflammation, pain, and potentially lead to vision loss if left untreated. Fungal Ear Infections (Otomycosis) FZ-3 can be used for treating fungal ear infections, also known as otomycosis, which is often caused by fungi like Aspergillus or Candida. Symptoms include itching, pain, and discharge from the ear canal. 🔹 How It Works Fluconazole is an antifungal agent that works by inhibiting the fungal enzyme lanosterol 14α-demethylase, which is involved in the synthesis of ergosterol, an essential component of the fungal cell membrane. By blocking this enzyme, fluconazole disrupts the fungal cell membrane, leading to fungal cell death or inhibition of growth. ⚠️ Common Side Effects Eye: Mild eye irritation or burning sensation upon application Blurred vision (temporary) Redness or stinging in the eyes Ear: Mild ear irritation Ear itching or discomfort after application Temporary hearing changes (rare) If any of these side effects persist or worsen, consult your healthcare provider. 🔹 Usage Tips Dosage: Typically, 1–2 drops are applied to the affected eye or ear 2–3 times daily, as prescribed by your doctor. Application Instructions: Wash your hands thoroughly before applying the drops. For the eyes: Tilt your head back and gently pull down the lower eyelid to form a pocket. Instill the prescribed number of drops and gently close your eye for a few seconds. For the ears: Tilt your head to one side, apply the drops into the ear canal, and gently massage the ear to help the drops penetrate. If you are using other medications for the eyes or ears, wait about 5 minutes between applying each medication. Contact Lenses: If you wear contact lenses, remove them before applying the drops to avoid any contamination. You can reinsert your lenses after 15 minutes. 🔹 Precautions Allergies: If you have a known allergy to fluconazole or other azole antifungals, do not use the drops. Pregnancy and Breastfeeding: Fluconazole should be used with caution in pregnancy, particularly during the first trimester. Always consult your doctor if you are pregnant or breastfeeding. Underlying Conditions: Inform your healthcare provider if you have any liver or kidney diseases, as these conditions may affect how the medication works in your body. Systemic Absorption: Although FZ-3 is used topically, there is a possibility of systemic absorption. Monitor for any systemic side effects, especially with prolonged use.

BIOFENAC Diclofenac Sodium USP is an anti-inflammatory eye drop used primarily to treat eye conditions that involve pain, swelling, and inflammation. It contains Diclofenac Sodium, which is a nonsteroidal anti-inflammatory drug (NSAID). 🔹 Primary Uses Post-Operative Inflammation BIOFENAC is commonly used after eye surgeries, such as cataract surgery, to help reduce inflammation and pain. Ocular Pain Relief It helps alleviate pain and discomfort caused by conditions like post-traumatic inflammation or other inflammatory eye conditions. Keratitis Treatment for inflammation of the cornea (keratitis), which can occur due to injury, infection, or other conditions. Conjunctivitis (inflammation of the conjunctiva) Can be used to manage eye inflammation caused by allergic reactions or other irritants. 🔹 How It Works Diclofenac Sodium is an NSAID that works by inhibiting the production of certain chemicals in the body known as prostaglandins, which are responsible for causing inflammation, pain, and swelling. By blocking these chemicals, BIOFENAC helps reduce inflammation and provides pain relief. ⚠️ Common Side Effects Stinging or burning upon application Eye irritation or redness Temporary blurred vision Dry eyes or feeling of a foreign body in the eye Sensitivity to light (photophobia) 🔹 Usage Tips Frequency: Typically used 2-4 times a day, depending on your doctor's recommendations, especially after surgery or for controlling inflammation. Application: Wash your hands before using the drops. Tilt your head back and pull down your lower eyelid to form a small pocket. Instill 1 drop into the pocket without touching the dropper to your eye. Gently close your eye and blink a few times to spread the medication evenly. If you need to use multiple eye medications, wait about 5–10 minutes between applications. Contact Lenses: Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them. 🔹 Precautions Eye Infections: Diclofenac may mask the symptoms of an eye infection. If you have an eye infection, consult your doctor before using this medication. Pregnancy and Breastfeeding: Consult your doctor if you are pregnant or breastfeeding, as NSAIDs may not be recommended in some cases. Allergies: If you have a history of allergic reactions to NSAIDs, aspirin, or other related medications, let your doctor know before using BIOFENAC. Long-Term Use: Prolonged use of NSAIDs can increase the risk of corneal damage or other complications, so it should be used with caution for extended periods.

DEXAPAR Dexamethasone Eye Drops contain Dexamethasone, a potent corticosteroid that helps to reduce inflammation in the eyes. These eye drops are typically used to manage a variety of eye conditions involving inflammation. Here’s a breakdown of the primary uses: 🔹 Primary Uses Treatment of Inflammatory Eye Conditions Dexamethasone is commonly used to treat eye conditions where inflammation is present, such as: Uveitis (inflammation of the uvea, which is part of the eye) Iritis (inflammation of the iris) Conjunctivitis (inflammation of the conjunctiva) Keratitis (inflammation of the cornea) Post-Surgical Inflammation Used after eye surgeries, such as cataract surgery, to control post-operative inflammation and prevent discomfort. Allergic Conjunctivitis May be used for severe allergic reactions causing inflammation in the eye (though often replaced by non-steroidal anti-inflammatory drugs or other treatments). 🔹 How It Works Dexamethasone is a corticosteroid that works by suppressing the immune system to decrease inflammation. It inhibits the release of substances in the body that cause inflammation, such as prostaglandins and cytokines. ⚠️ Common Side Effects Eye irritation or stinging upon application Increased intraocular pressure (which can lead to glaucoma with long-term use) Blurred vision (temporary) Cataract formation (with prolonged use) Eye infections: Prolonged use may increase the risk of developing eye infections. 🔹 Usage Tips Dosage: Typically, 1–2 drops in the affected eye(s), 2 to 4 times a day, depending on the severity of inflammation. Application: Wash your hands before using the eye drops. Tilt your head back and pull down your lower eyelid to form a pocket. Drop the medication into the pocket and close your eye gently. Blink to spread the medication evenly. If using multiple eye medications, wait about 5 minutes between applying each. Contact Lenses: Remove contact lenses before applying the drops and wait 15 minutes before reinserting them. 🔹 Precautions Glaucoma and Cataracts: Prolonged use of Dexamethasone can increase the risk of glaucoma and cataracts, especially in people with a history of these conditions. Infections: Dexamethasone may mask signs of infection. Be cautious if you have an active eye infection. Pregnancy and Breastfeeding: Consult your doctor if you are pregnant or breastfeeding, as corticosteroids may not be suitable in these situations. Long-Term Use: Prolonged or repeated use of corticosteroid eye drops requires careful monitoring by an eye care professional. 🔹 Long-Term Use Dexamethasone Eye Drops are generally not recommended for long-term use unless prescribed by a doctor because of the risk of increasing intraocular pressure, glaucoma, and other complications like cataract formation.