Methylene Blue Injection is a versatile medication with several clinical uses. It’s a synthetic dye that also functions as a medicinal agent, especially in emergency and critical care settings. ✅ Primary Medical Uses of Methylene Blue Injection Methemoglobinemia Treatment Main use: It rapidly treats methemoglobinemia, a condition where hemoglobin can’t carry oxygen effectively. Converts methemoglobin (Fe³⁺) back to normal hemoglobin (Fe²⁺), restoring oxygen delivery. Urinary Tract Antiseptic (rarely used today) Has mild antiseptic properties in the urinary tract when used with other agents. Ifosfamide-Induced Encephalopathy Used off-label to counteract neurotoxicity caused by the chemotherapy drug ifosfamide. Intraoperative Staining Agent Surgeons and urologists may use it to identify structures (e.g., fistulas, ureters, sentinel lymph nodes). Vasoplegic Syndrome in Cardiac Surgery (off-label) Helps raise blood pressure in cases of refractory hypotension after heart surgery, by inhibiting nitric oxide pathways. Diagnostic Aid Sometimes used to help visualize certain body structures or to test for leaks (like gastrointestinal perforations). ⚠️ Important Warnings & Precautions Serotonin Syndrome Risk: Methylene blue is a monoamine oxidase inhibitor (MAOI) — do not use with SSRIs, SNRIs, or other serotonergic drugs. G6PD Deficiency: Can cause hemolysis in people with glucose-6-phosphate dehydrogenase deficiency. Pregnancy: Generally avoided unless absolutely necessary. 💉 Side Effects Pain at the injection site Nausea, vomiting Headache, dizziness Blue or green discoloration of urine, stool, or skin (temporary and harmless) High doses: confusion, agitation, or chest pain

Gufipol 5,00,000Unit Injection contains an active component as Polymyxin B. This medication is an antibiotic medication used to treat various bacterial infections, especially those caused by Gram-negative bacteria. It is commonly used when other antibiotics are ineffective or when dealing with multi-drug-resistant bacteria. It may be prescribed for conditions such as urinary tract infections, pneumonia, bacterial skin infections, and ventilator-associated pneumonia. A urinary tract infection (UTI) is a bacterial infection that affects the urinary system, primarily the bladder, urethra, or kidneys. Pneumonia is a respiratory condition characterized by inflammation of the lungs, usually caused by infection from bacteria, viruses, or fungi. Ventilator-associated pneumonia (VAP) is a type of lung infection that occurs in patients who are on mechanical ventilation in the hospital, typically caused by bacteria entering the lungs through the ventilator tube. Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Gufipol Anaphylactic reaction Fever Kidney damage Neurotoxicity Injection site reactions (pain, swelling, redness)

Colistican 3 Injection is an intravenous formulation containing Colistimethate Sodium 3 Million IU, manufactured by American Remedies. It is primarily used to treat severe infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 3 Injection Colistican 3 Injection is indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bloodstream Infections (Sepsis): Infections caused by resistant bacteria entering the bloodstream. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. • Intra-abdominal Infections: Such as peritonitis. • Cystic Fibrosis: For chronic pulmonary infections due to Pseudomonas aeruginosa in both adults and children. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

Colistican 2 Injection is a brand of Colistimethate Sodium for Injection, manufactured by American Remedies. It is a polymyxin-class antibiotic used to treat serious infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 2 Injection Colistican 2 Injection is primarily indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bacteremia (Bloodstream Infection): Infections caused by resistant bacteria entering the bloodstream. • Lower Respiratory Tract Infections: Including severe cases of pneumonia and bronchitis. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. These infections are typically caused by pathogens such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae, which are resistant to multiple antibiotics. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

Colistican 1 Injection is a brand of Colistimethate Sodium for Injection manufactured by American Remedies. Colistimethate sodium is a polymyxin-class antibiotic, also known as polymyxin E, used to treat serious infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 1 Injection Colistican 1 Injection is primarily used for: • Multidrug-Resistant Infections: Especially those caused by Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Urinary Tract Infections (UTIs): Caused by resistant Gram-negative bacteria. • Bloodstream Infections (Sepsis): Resulting from resistant pathogens. • Intra-abdominal Infections: Such as peritonitis. • Cystic Fibrosis: For chronic pulmonary infections due to Pseudomonas aeruginosa in both adults and children. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

Pregafox 300 Capsules – Pregabalin 300mg Pregafox 300 Capsules – Trusted Pregabalin 300mg Exporter & Dropshipper Worldwide 📧 Email: exports@ernestpharmaceuticals.com 📲 WhatsApp: +91 94054 76170 – Message us today for the best export & dropshipping deal 🌐 Websites: www.ernestpharmaceuticals.com | www.ernestimpex.com Pregafox 300 Capsules – Pregabalin 300mg Product Name: Pregafox 300 Capsules Active Ingredient: Pregabalin 300mg Form: Hard Gelatin Capsule Pack Size: As per requirement (usually blister packs or bottles) Product Description: Pregafox 300 Capsules contain Pregabalin 300mg, an anticonvulsant and neuropathic pain reliever. Pregabalin works by calming overactive nerve signals in the brain, which helps reduce pain, seizures, and anxiety symptoms. It is widely prescribed for managing chronic nerve-related pain and certain anxiety disorders. Uses of Pregafox 300 Capsules: Treatment of neuropathic pain caused by diabetes, shingles, spinal cord injury, or nerve damage As an adjunct therapy for partial-onset seizures in epilepsy Management of fibromyalgia (widespread muscle pain and tenderness) Treatment of generalized anxiety disorder (GAD) in adults Key Benefits: Provides long-lasting relief from nerve pain Improves quality of sleep by reducing nighttime discomfort Helps in better control of seizures when used with other medications Effective in reducing muscle pain and anxiety symptoms Dosage & Administration: Usual recommended dose: as directed by a healthcare professional Taken orally with water, with or without food Dosage may vary depending on patient condition and medical advice Safety Information: Should be taken only under medical supervision Possible side effects: dizziness, drowsiness, blurred vision, weight gain, dry mouth Avoid alcohol consumption during treatment Not recommended in pregnancy or breastfeeding unless advised by a doctor Storage: Store in a cool, dry place away from direct sunlight Keep out of reach of children

Bonhans is a nutritional supplement that can be used to strengthen joints and cartilage in growing puppies and active adult dogs. It is also indicated for use in dogs diagnosed with mild to moderate osteoarthritis, a disease caused by loss of cartilage and thinning of synovial membrane leading to pain, inflammation and stiffness. Bonhans helps during recovery from fracture & joint surgeries too and can also be used in patients with hip & elbow dysplasia.

Kidney disease is a silent killer in dogs & cats. In older population, as many as 10% of dogs and 35% cats have chronic kidney disease. Kynetra is a kidney health support formula that contains proven Chinese herbs and vitamins that help to maintain and support kidney function. has potential to slow down the progression of kidney disease. Kynetra contains scientifically proven Chinese herbs, Rehmannia glutinosa, Astragalus, Cordycepsus sinensis, is indicated for AKI – Acute Kidney Injury & Chronic CKD Conditions Slows down CKD Progression Supplementation is beneficial in CKD including nephropathy secondary to diabetes, and hypertension Helps in recovery from vitamin deficiency caused by CKD Has shown potential to decrease serum creatinine, increase creatine clearance Reduce proteinuria and alleviate CKD-associated complications Helps in preventing damage to nephrons from oxidative stress caused by CKD. Improves Kidneys function by reducing excretion of proteins. Acts as reno protective.

Galibor contains the secondary bile acid, Ursodeoxy cholic acid (UDCA) and is used as an adjunctive tehrapy for patients with liver disease, particularly where cholestasis is present. Cholestasis is a condition in which the flow of bile from the liver stops or slows. Bile is a digestive fluid and the reduced flow of bile and can be caused by a liver infection, gallstones, cancer and drugs.