Tropind (Tropicamide 1%) Ophthalmic Solution is commonly used for the following purposes: Pupillary Dilation (Mydriasis): Tropind is often used by eye care professionals to dilate the pupils during eye exams, such as fundoscopy or slit-lamp examinations. It helps them get a clear view of the retina, optic nerve, and other structures inside the eye. Cycloplegia: Tropind is used to temporarily paralyze the ciliary muscle in the eye, which controls the lens's focusing ability. This is useful during certain types of eye exams, such as refraction tests, to evaluate the eye's refractive error without interference from accommodation (focusing). Treatment of Certain Eye Conditions: It may also be used to treat or manage certain eye conditions, such as uveitis (inflammation of the middle layer of the eye), to relieve pain and prevent further spasms of the eye muscles. How it works: Tropind contains tropicamide, which is an anticholinergic agent that works by blocking the action of acetylcholine on the muscles of the iris (pupil) and the ciliary body, causing pupil dilation and paralysis of accommodation. Administration: It is usually instilled directly into the eye as drops. The effects typically last for a few hours, depending on the individual and the purpose of use. Side effects: Potential side effects may include temporary blurry vision, sensitivity to light (due to pupil dilation), or stinging when the drops are first applied. Always follow the instructions provided by your healthcare provider or the product label when using Tropind.

F M N Eye Drops contain Fluorometholone, a corticosteroid used to treat inflammation and other related conditions of the eyes. Here's an overview of its uses: 🔹 Primary Uses Anti-Inflammatory Treatment Fluorometholone is a mild corticosteroid that helps reduce inflammation in the eye. It is often prescribed for conditions like conjunctivitis (inflammation of the conjunctiva), iritis (inflammation of the iris), and uveitis (inflammation of the uvea, the middle layer of the eye). Post-Surgical Inflammation It is commonly used to control inflammation and swelling after eye surgeries, such as cataract surgery or other procedures, to help reduce discomfort and promote healing. Allergic Eye Conditions Fluorometholone may be used for treating allergic reactions that cause eye redness, itching, and swelling, such as in seasonal allergic conjunctivitis or vernal keratoconjunctivitis. Eye Infections (with inflammation) In some cases, it may be used for eye infections that cause inflammation, although it's important to note that it should not be used for infections caused by viruses, fungi, or bacteria unless combined with other appropriate treatments. 🔹 How It Works Fluorometholone is a steroid that works by suppressing the immune response in the eye. It inhibits the production of chemicals called prostaglandins, which are responsible for causing inflammation, swelling, and pain. By reducing inflammation, the drops help relieve symptoms like redness, swelling, and discomfort. ⚠️ Common Side Effects Eye irritation, burning, or stinging upon application Blurred vision (usually temporary) Increased intraocular pressure (IOP) with prolonged use, which may lead to glaucoma or cataract formation Redness or dryness of the eyes Sensitivity to light (photophobia) Watering eyes 🔹 Usage Tips Dosage: Typically, 1-2 drops are applied to the affected eye(s), 2 to 4 times a day, or as prescribed by your doctor. Application Instructions: Wash your hands thoroughly before applying the drops. Tilt your head back and gently pull down the lower eyelid to form a small pocket. Place 1 drop in the pocket, and then gently close your eye and blink a few times to spread the medication evenly across the eye. If using other eye medications, wait 5–10 minutes between each. Contact Lenses: Remove contact lenses before applying the drops and wait 15 minutes before reinserting them. 🔹 Precautions Infections: Avoid using Fluorometholone if you have an active eye infection (especially viral or fungal), as corticosteroids can suppress the immune response and worsen infections. Eye Pressure: Fluorometholone can increase the intraocular pressure (IOP) over time, which may lead to glaucoma. It is important to monitor IOP regularly if used long-term. Pregnancy and Breastfeeding: Consult your doctor before using this medication if you are pregnant or breastfeeding, as corticosteroids should be used cautiously in these situations. Prolonged Use: Long-term use of corticosteroid eye drops should be under close supervision of a healthcare provider, as it can lead to complications like cataracts or glaucoma.

BIOFENAC Diclofenac Sodium USP is an anti-inflammatory eye drop used primarily to treat eye conditions that involve pain, swelling, and inflammation. It contains Diclofenac Sodium, which is a nonsteroidal anti-inflammatory drug (NSAID). 🔹 Primary Uses Post-Operative Inflammation BIOFENAC is commonly used after eye surgeries, such as cataract surgery, to help reduce inflammation and pain. Ocular Pain Relief It helps alleviate pain and discomfort caused by conditions like post-traumatic inflammation or other inflammatory eye conditions. Keratitis Treatment for inflammation of the cornea (keratitis), which can occur due to injury, infection, or other conditions. Conjunctivitis (inflammation of the conjunctiva) Can be used to manage eye inflammation caused by allergic reactions or other irritants. 🔹 How It Works Diclofenac Sodium is an NSAID that works by inhibiting the production of certain chemicals in the body known as prostaglandins, which are responsible for causing inflammation, pain, and swelling. By blocking these chemicals, BIOFENAC helps reduce inflammation and provides pain relief. ⚠️ Common Side Effects Stinging or burning upon application Eye irritation or redness Temporary blurred vision Dry eyes or feeling of a foreign body in the eye Sensitivity to light (photophobia) 🔹 Usage Tips Frequency: Typically used 2-4 times a day, depending on your doctor's recommendations, especially after surgery or for controlling inflammation. Application: Wash your hands before using the drops. Tilt your head back and pull down your lower eyelid to form a small pocket. Instill 1 drop into the pocket without touching the dropper to your eye. Gently close your eye and blink a few times to spread the medication evenly. If you need to use multiple eye medications, wait about 5–10 minutes between applications. Contact Lenses: Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them. 🔹 Precautions Eye Infections: Diclofenac may mask the symptoms of an eye infection. If you have an eye infection, consult your doctor before using this medication. Pregnancy and Breastfeeding: Consult your doctor if you are pregnant or breastfeeding, as NSAIDs may not be recommended in some cases. Allergies: If you have a history of allergic reactions to NSAIDs, aspirin, or other related medications, let your doctor know before using BIOFENAC. Long-Term Use: Prolonged use of NSAIDs can increase the risk of corneal damage or other complications, so it should be used with caution for extended periods.

DEXAPAR Dexamethasone Eye Drops contain Dexamethasone, a potent corticosteroid that helps to reduce inflammation in the eyes. These eye drops are typically used to manage a variety of eye conditions involving inflammation. Here’s a breakdown of the primary uses: 🔹 Primary Uses Treatment of Inflammatory Eye Conditions Dexamethasone is commonly used to treat eye conditions where inflammation is present, such as: Uveitis (inflammation of the uvea, which is part of the eye) Iritis (inflammation of the iris) Conjunctivitis (inflammation of the conjunctiva) Keratitis (inflammation of the cornea) Post-Surgical Inflammation Used after eye surgeries, such as cataract surgery, to control post-operative inflammation and prevent discomfort. Allergic Conjunctivitis May be used for severe allergic reactions causing inflammation in the eye (though often replaced by non-steroidal anti-inflammatory drugs or other treatments). 🔹 How It Works Dexamethasone is a corticosteroid that works by suppressing the immune system to decrease inflammation. It inhibits the release of substances in the body that cause inflammation, such as prostaglandins and cytokines. ⚠️ Common Side Effects Eye irritation or stinging upon application Increased intraocular pressure (which can lead to glaucoma with long-term use) Blurred vision (temporary) Cataract formation (with prolonged use) Eye infections: Prolonged use may increase the risk of developing eye infections. 🔹 Usage Tips Dosage: Typically, 1–2 drops in the affected eye(s), 2 to 4 times a day, depending on the severity of inflammation. Application: Wash your hands before using the eye drops. Tilt your head back and pull down your lower eyelid to form a pocket. Drop the medication into the pocket and close your eye gently. Blink to spread the medication evenly. If using multiple eye medications, wait about 5 minutes between applying each. Contact Lenses: Remove contact lenses before applying the drops and wait 15 minutes before reinserting them. 🔹 Precautions Glaucoma and Cataracts: Prolonged use of Dexamethasone can increase the risk of glaucoma and cataracts, especially in people with a history of these conditions. Infections: Dexamethasone may mask signs of infection. Be cautious if you have an active eye infection. Pregnancy and Breastfeeding: Consult your doctor if you are pregnant or breastfeeding, as corticosteroids may not be suitable in these situations. Long-Term Use: Prolonged or repeated use of corticosteroid eye drops requires careful monitoring by an eye care professional. 🔹 Long-Term Use Dexamethasone Eye Drops are generally not recommended for long-term use unless prescribed by a doctor because of the risk of increasing intraocular pressure, glaucoma, and other complications like cataract formation.

CYCLOSIM 0.1% Eye Drops contain Cyclosporine A, which is an immunosuppressive drug. These eye drops are primarily used for conditions related to dry eyes and inflammation. Here's a detailed overview of its uses: 🔹 Primary Uses Treatment of Dry Eye Disease (Keratoconjunctivitis Sicca) Cyclosporine A in CYCLOSIM 0.1% is commonly used to treat dry eye disease associated with inflammation. It helps by increasing tear production and reducing the inflammation in the eye, making it useful for those who have chronic dry eye caused by insufficient tear production. Inflammatory Eye Conditions It can help reduce inflammation in the eyes, particularly in conditions where the immune system is involved in causing eye irritation or dry eye symptoms. 🔹 How It Works Cyclosporine A is an immunosuppressive agent that modulates the immune system by inhibiting the production of certain cytokines (especially interleukin-2). In the context of dry eyes, this helps to reduce inflammation in the tear glands and promotes tear production. ⚠️ Common Side Effects Burning or stinging sensation in the eye upon application Redness in the eye Eye discomfort or feeling of a foreign object in the eye Watery eyes Temporary blurred vision (typically resolves shortly after application) 🔹 Usage Tips Frequency: Typically applied twice a day, about 12 hours apart, in each affected eye. Application: Wash your hands thoroughly before using the drops. Tilt your head back and pull down the lower eyelid to form a small pocket. Instill 1 drop into the pocket of the lower eyelid. Close your eye gently and blink several times to help spread the medication. If you use other eye medications, wait at least 5–10 minutes between applications. Contact Lenses: Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting. 🔹 Precautions Infections: If you have an active eye infection, this medication may not be appropriate as it could exacerbate it. Pregnancy and Breastfeeding: Consult your doctor if you are pregnant or breastfeeding before using Cyclosporine A eye drops. Other Medications: Always inform your doctor if you are using other eye medications or oral medications that may interact with Cyclosporine.

INTRODUCTION ABALAM 600/300 is a combination of Abacavir and Lamivudine which belongs to the group of medicines called Anti-viral agents. It is used in the management of HIV infection in adults, adolescents and in children (weighing above 25 kgs). HIV (human immunodeficiency virus) infection is a viral infection that damages our immune system and weakens our body’s ability to fight against various infections. Both abacavir and lamivudine are nucleoside reverse transcriptase inhibitors. They work by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. This prevents further multiplication of viral cells within the body. Also, they can improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. ABALAM 600/300 cannot not manage HIV infection completely. It can reduce only the number of viral cells present in the body and maintains them at a lower level. During management with ABALAM 600/300 your doctor will closely monitor your body weight, blood cholesterol levels and blood sugar levels to reduce the risk of unwanted side effects. Do not take ABALAM 600/300 if you are allergic to abacavir or lamivudine. Before taking ABALAM 600/300 inform your doctor if you have diabetes or any liver (hepatitis C or B infection), kidney or heart problems. If you are already taking ABALAM 600/300 to manage hepatitis B or C infection, do not stop taking it without consulting your doctor. Even if you take ABALAM 600/300, it is important for you to follow certain measures to prevent the spread of infections to the other people (such as avoid having unprotected sexual intercourse or sharing needles or personal items like toothbrush, razors etc with other people). ABALAM 600/300 is not recommended for use in pregnant or breastfeeding women. The most common side effects of taking ABALAM 600/300 are difficulty in sleeping, increased signs of infections, nausea, stomach pain, headache, or dizziness. Consult your doctor if any of these side effects worsens. Also inform your doctor immediately if you experience severe fever with extreme tiredness, sudden changes in body weight or severe stomach pain along with dark urine after taking ABALAM 600/300. USES OF ABALAM 600/300 Manages HIV infection in adults, adolescents and in children (weighing above 25 kgs) HOW ABALAM 600/300 WORKS ABALAM 600/300 is an anti-retroviral medicine. It controls the multiplication of viral cell within the body, by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. It can also improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. DIRECTIONS FOR USE Take ABALAM 600/300 as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. ABALAM 600/300 can be taken with or without meals. Your doctor will decide the correct dose and for how long ABALAM 600/300 must be taken depending upon your age, body weight and severity of the infection. Do not stop taking ABALAM 600/300 without consulting your doctor as it may reduce its effectiveness. SIDE EFFECTS OF ABALAM 600/300 COMMON difficulty in sleeping feeling depressed headache, tiredness, dizziness nausea, diarrhoea fever, skin rash stomach pain loss of appetite irritated or runny nose hair loss UNCOMMON decrease in RBC, WBC, and platelets RARE Stop taking ABALAM 600/300 and contact your doctor immediately if you experience any of the following side effects: signs of allergic reactions (such as skin rash, fever, accompanied with sore throat, cough, nausea, vomiting, stomach pain, diarrhea, tiredness, joint pain, muscle pain, swelling of the neck, difficulty in breathing, mouth ulcers, occasional headaches, inflammation of the eye, low blood pressure, sense of tingling or numbness of hands or feet) pure red cell aplasia (failure of bone marrow to produce new red blood cells) signs of infections (such as fever, headache, stomach-ache, breathing difficulty) signs of auto-immune disorders (such as rapid or irregular heartbeat, tremor, hyperactivity, general weakness) signs of osteonecrosis (death of bone cells causing joint stiffness, pain in the hip, knee or shoulder and difficulty in moving) signs of liver problems (such as yellowing of the skin and whites of the eye, dark urine, light-coloured stools, loss of appetite, nausea, pain, tenderness on the right side of stomach) heart attack changes in body fat (such as increase fat in the shoulder and neck (buffalo hump), breast, and in the middle body or fat loss from the legs, arms, or face)

Marketer Intas Pharmaceuticals Ltd SALT COMPOSITION Recombinant Human Erythropoietin Alfa (6000IU) Salt Synonyms Epoetin Alfa Storage Store in a refrigerator (2 - 8°C). Do not freeze. Uses of Renocel Injection Anemia due to chronic kidney disease Anemia due to cancer chemotherapy Product introduction Renocel 6000IU Injection is a medicine that helps your bone marrow to produce more red blood cells. It is used to treat a type of anemia caused by kidney disease. It is also used to treat anemia caused by cancer chemotherapy and by taking medicines to treat HIV. Renocel 6000IU Injection is given by injection either under the skin or into a vein which will be decided by your doctor. Usually, the injections are given by a nurse or doctor. The dose depends on your body weight and the cause of your anemia. Iron supplements both before and during treatment may make this treatment more effective. Renocel 6000IU Injection needs to be stored in a fridge but used at room temperature. The most common side effects of taking this medicine include nausea, vomiting, fever, and increased blood pressure. It may also cause flu-like symptoms such as headache, tiredness, dizziness and aches and pains. These side effects are most common at the start of treatment but if they persist your doctor may be able to suggest ways of preventing or reducing them. Tell your doctor straight away if you get any serious side effects, including seizures (fits). Sometimes this medicine can cause serious blood clots that need urgent medical attention. Before using Renocel 6000IU Injection you should tell your doctor if you have uncontrolled high blood pressure, heart disease, or gout (disease of joint pain). You should also tell him/her what other medicines you are taking in case they affect this treatment. Your blood pressure should be checked often during this treatment by you or your doctor. You may also need other regular medical tests to be sure this medicine is not causing harmful effects. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. Side effects of Renocel Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Renocel High blood pressure Nausea Vomiting Fever Rash Joint pain Headache Insomnia (difficulty in sleeping) Chills Cough Bone pain Muscle spasm Dizziness Vascular occlusion Injection site irritation Stomatitis (Inflammation of the mouth) Weight loss Decreased white blood cell count (lymphocytes) Increased glucose level in blood Blood clot in the blood vessels How to use Renocel Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Renocel Injection works Renocel 6000IU Injection is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Renocel 6000IU Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Renocel 6000IU Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Renocel 6000IU Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Introduction to Xapavir 50mg Tablet Xapavir 50mg Tablet is an antiviral drug belonging to the Integrase strand transfer inhibitor category, containing the active ingredient Dolutegravir. It is used to treat human immunodeficiency virus (HIV) infection. HIV infection is mainly spread by sexual contact with anyone who has the infection or by transfer of infected blood (by sharing injection needles). This drug must be taken with other medicines used to treat HIV infection. This drug is contraindicated in individuals with liver disease. Due to the higher concentration, caution should be taken when administering the drug to individuals with liver impairment. The dosage of this drug may need to be adjusted by your doctor, or it may need to be used with extra monitoring in these individuals to ensure its safety and efficacy. During the early stages of HIV treatment, some patients may experience an inflammatory response to opportunistic infections. This condition, immune reconstitution syndrome, can occur after starting the drug or other antiretroviral therapies. Knowing this possibility and monitoring for any signs of worsening infections or inflammatory symptoms is necessary. Inform your healthcare provider if the symptoms concern you or persist longer than usual. It is necessary for healthcare professionals to carefully monitor patients taking this drug for any signs or symptoms of skin or hypersensitivity reactions, such as rash, blistering, or mucosal lesions. If a severe reaction is suspected, this medicine should be discontinued immediately, and appropriate medical treatment can be initiated. Patients are also advised to report any skin or hypersensitivity reactions to their healthcare provider and to seek medical emergency immediately if they experience any symptoms of a severe reaction. Tell your doctor immediately about all the medications you have been taking recently, including herbal and supplements, before taking this drug. Uses of Xapavir 50mg Tablet Human Immunodeficiency Virus (HIV) Therapeutic Effects of Xapavir 50mg Tablet Xapavir 50mg Tablet works by inhibiting the enzyme integrase, thereby reducing the virus in your body. It also increases a type of white blood cell called CD4 cells which help the body fight infection. Interaction of Xapavir 50mg Tablet with other drugs Inform your healthcare provider about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Xapavir 50mg Tablets and reduce effectiveness by causing undesirable side effects. More Information about Xapavir 50mg Tablet Store Xapavir 50mg Tablet at room temperature (15°to 25°C). Keep the Tablet out of reach of children and pets. How to consume Xapavir 50mg Tablet It is an orally available prescription drug. Your doctor will decide the dose and duration of the drug based on the disease condition and other factors. Always take Xapavir 50mg Tablet as prescribed by your doctor. Take the Tablet with or without food. Do not break, chew, or crush the Tablet. Swallow the whole Tablet with water. Safety Advices for Xapavir 50mg Tablet Image Not Available Pregnancy Suppose you are pregnant or planning for pregnancy during the treatment. Please consult your doctor before taking Xapavir 50mg Tablet. Image Not Available Breast Feeding Breastfeeding is not recommended in patients taking Xapavir 50mg Tablets because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment. Image Not Available Lungs It is unknown whether Xapavir 50mg Tablets can be prescribed for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment. Image Not Available Liver Xapavir 50mg Tablet must be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary for severe liver failure. Inform your doctor if you have liver problems before initiating the therapy Image Not Available Alcohol Consuming alcohol may affect the effectiveness of the Xapavir 50mg Tablet. It is highly advised to stop consuming alcohol if you take this medicine. Image Not Available Driving Driving vehicles or operating heavy machinery is unsafe after taking the Xapavir 50mg Tablet. It may cause dizziness and impair concentration. Side Effects of Xapavir 50mg Tablet Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Allergic reactions (swelling, high temperature) Infection, inflammation Inflammation of the liver; liver failure Joint pain Common Depression Abnormal dreams, insomnia Itching, rash Being sick Stomach discomfort, pain Headache Diarrhea Fatigue

Combinib 250mg Tablet is used in the treatment of breast cancer. It works by stopping or slowing down the growth of cancer cells. It is either used alone or in combination with some other medicine to cure advanced-stage breast cancer. Combinib 250mg Tablet should be taken on an empty stomach or an hour before or 2 hours after a meal. The dose and duration vary according to the severity of your condition and your response to treatment. Take it exactly as prescribed to avoid serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include nausea, headache, back pain, and breathing difficulty. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. You may be asked for regular monitoring of blood pressure while taking this medicine. Inform your doctor if you notice a severe headache, confusion, problems with your eyesight, nausea, or vomiting. Your doctor may check your liver function before, during, and after treatment with this medicine. Before taking Combinib 250mg Tablet, let your doctor know if you have liver or kidney problems. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are taking. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details. Uses of Combinib Tablet Pancreatic cancer Small cell lung cancer Liver cancer Kidney cancer Thyroid cancer Blood cancer (Chronic myeloid leukaemia) Gastrointestinal stromal tumour Cancer of colon and rectum Non-small cell lung cancer Soft tissue sarcoma Chronic idiopathic myelofibrosis Breast cancer Side effects of Combinib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Combinib Abdominal pain Back pain Breathing problems Constipation Cough Diarrhea Fatigue Headache Hot flashes Increased bilirubin in the blood Insomnia (difficulty in sleeping) Joint pain Liver damage Loss of appetite Mucosal inflammation Nausea Pain in extremities Rash Stomatitis (Inflammation of the mouth) Vomiting Weakness Weight gain How to use Combinib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combinib 250mg Tablet is to be taken empty stomach. How Combinib Tablet works Combinib 250mg Tablet is an anti-cancer medication. It works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which are responsible for the over-proliferation of cells. This is how it inhibits the growth of cancerous cells causing downstream signaling pathways. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Combinib 250mg Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Combinib 250mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Combinib 250mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Combinib 250mg Tablet may cause side effects which could affect your ability to drive. warnings Kidney CAUTION Combinib 250mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Combinib 250mg Tablet may be needed. Please consult your doctor. Limited information is available on the use of Combinib 250mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease. warnings Liver CAUTION Combinib 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Combinib 250mg Tablet may be needed. Please consult your doctor. Limited information is available on the use of this medicine in patients with the severe liver disease.