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General Medicine

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

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General Medicine

Milrican 10 is a brand of Milrinone Lactate Injection, manufactured by American Remedies. Milrinone is a phosphodiesterase-3 (PDE3) inhibitor that serves as both an inotropic agent and a vasodilator. ________________________________________ ✅ Primary Uses of Milrican 10 Milrican 10 is indicated for the short-term intravenous treatment of: • Severe congestive heart failure: Particularly in patients unresponsive to conventional therapies. • Acute decompensated heart failure: Including low output states following cardiac surgery. It is commonly used in intensive care units or during cardiac procedures to support heart function. ________________________________________ ⚙️ Mechanism of Action Milrinone works by inhibiting PDE3, leading to increased cyclic AMP (cAMP) levels in cardiac and vascular smooth muscle cells. This results in: • Increased myocardial contractility: Enhancing the heart's ability to pump blood. • Vasodilation: Relaxing blood vessels, which reduces the heart's workload and improves blood flow. ________________________________________ ⚠️ Important Considerations • Administration: Milrican 10 should only be administered intravenously under the supervision of a healthcare professional. • Monitoring: Patients receiving Milrican 10 require close monitoring of blood pressure, heart rate, and kidney function. • Contraindications: Not recommended for patients with severe dehydration, electrolyte imbalances, or known hypersensitivity to milrinone. • Pregnancy and Breastfeeding: Consult a doctor before use if pregnant or breastfeeding.

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Heart Disorder

Dopan 200mg Injection Salt Composition : Dopamine Hydrochloride Manufacturer : CELON LABORATORIES LTD Introduction to Dopan 200mg Injection Dopan 200mg injection contains the active ingredient Dopamine hydrochloride. It is used to treat low blood pressure and helps improve the muscle contraction strength in the heart. It also aids in improving low blood pressure due to open heart surgery, injury, congestive heart failure, heart attack, blood poisoning, and infection. Inform your doctor before using Dopan 200mg injection if you are pregnant or breastfeeding, if you have heart problems, liver or kidney problems, sulphite sensitivity, a tumor, narrow-angle glaucoma, diabetes, blood disorder, hyperthyroidism, or if you have been taking antidepressants. Headache, nausea and vomiting, palpitation, trouble breathing (dyspnoea), low blood pressure, and chest pain are common side effects seen with the use of Dopan 200mg injection. Uses of Dopan 200mg Injection In treating low blood pressure or shock due to heart attack, trauma, or injury In treating low blood pressure due to blood infections or blood poisoning To treat congestive heart failure In combination with other treatments to treat low blood pressure after open heart surgery. Therapeutic Effects of Dopan 200mg Injection Dopan 200mg injection works by producing an ionotropic effect on the muscles of the heart, which causes an increase in the strength of heart muscle contractions and heart rate. As a result of this, there is an increase in blood pressure and cardiac output. Interaction of Dopan 200mg Injection with other drugs Inform your healthcare professional about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications belong to Tricyclic antidepressant drugs, and interacting with Dopan 200mg injection may reduce effectiveness by causing undesirable side effects. More Information about Dopan 200mg Injection Keep Dopan 200mg injection out of the reach and sight of children. Do not store above 25°C. How to consume Dopan 200mg Injection Dopan 200mg injection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person. Safety Advices for Dopan 200mg Injection Image Not Available Pregnancy If you are planning a pregnancy or think you may be pregnant, inform your doctor. Dopan 200mg injection might be unsafe during pregnancy because it can harm the unborn baby. Image Not Available Breast Feeding Inform your doctor in case you are breastfeeding since it is unknow whether Dopan 200mg injection is good for breast milk or not. Image Not Available Lungs It is unknown whether Dopan 200mg injection is safe for lung conditions. So consult your doctor in case you have any lung disease before starting the treatment. Image Not Available Liver Inform your doctor in case you have any liver diseases before starting treatment with Dopan 200mg injection. Image Not Available Alcohol It is unknown whether consuming alcohol while taking a Dopan 200 mg injection is safe. Please speak with your physician. Image Not Available Driving Instructions for driving are not applicable as Dopan 200mg injection is administered at the hospital. Side Effects of Dopan 200mg Injection Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

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Heart Disorder

Dobier S 50mg Injection Salt: Dobutamine (50mg) INTRODUCTION ABOUT DOBIER S 50MG INJECTION DOBIER S 50MG INJECTION contains Dobutamine which belongs to the group of medicines called Cardiac Stimulants. It is used to improve heart functions. It restores heartbeat and blood pressure to normal levels among patients undergoing open heart surgery and in patients having heart failure or any other severe heart conditions that reduces heart rate (such as shock or cardiomyopathies (enlargement of heart muscles)). It can also be used as an alternative to exercise during stress testing (a procedure used to detect heart problems). DOBIER S 50MG INJECTION is suitable for use both in adults and in children (including infants). Before receiving DOBIER S 50MG INJECTION inform your doctor if you have asthma or any other respiratory disorders. You must also inform your doctor if you have any allergic conditions or low blood volume as a precaution. DOBIER S 50MG INJECTION is not suitable for stress testing in patients having any heart or blood vessels disorders that hinder blood flow. It is also not recommended for use in pregnant and in breastfeeding women unless considered necessary by the physician. The most common side effects of receiving DOBIER S 50MG INJECTION are fast heartbeat, headache, high or low blood pressure, shortness of breath, inflammation at the injection site, nausea and urge to pass urine. Consult your doctor if any of these side effects worsens. USES OF DOBIER S 50MG INJECTION Improves heart functions by restoring normal heartbeat and blood pressure Manage heart failure Manage shock (cardiogenic or septic shock) Manage any heart conditions that may result in poor circulation around the body (such as cardiomyopathies, open heart surgery) Used as an alternative to exercise during stress testing HOW DOBIER S 50MG INJECTION WORKS DOBIER S 50MG INJECTION is a cardiac stimulant. It stimulates the heart and improves heart functions. It helps your heart to work more effectively by strengthening the pumping action of the heart. It also improves blood circulation around the body by expanding the blood vessels present all over the body. DIRECTIONS FOR USE DOBIER S 50MG INJECTION will be given only by a doctor or by a trained healthcare professional into the vein (intravenously). Your doctor will decide the correct dose, duration of therapy and site of administration for you depending upon your age, body weight and health condition. SIDE EFFECTS OF DOBIER S 50MG INJECTION COMMON increased heart rate chest pain abnormal heartbeat, palpitations high or low blood pressure narrowing of the blood vessels headache wheezing, shortness of breath increase in WBC count in blood increased bleeding tendency urge to pass urine nausea skin rash fever inflammation at the injection site HOW TO MANAGE SIDE EFFECTS Headache: Try to take rest. Apply a pain-relieving balm on your forehead. If the symptom does not improve, consult with your doctor. Nausea: Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your symptom worsens. Skin rash: Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash worsens. Inflammation at the site of injection: Place an ice pack on the injected site. Do not move the affected area frequently. If the symptom worsens, consult your doctor. WARNING & PRECAUTIONS PREGNANCY DOBIER S 50MG INJECTION is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, inform your doctor before receiving this medicine if you are pregnant or think you may be pregnant or planning to have a baby. BREASTFEEDING DOBIER S 50MG INJECTION is not recommended for use in breastfeeding women. Therefore, inform your doctor before receiving this medicine if you are breastfeeding. DRIVING AND USING MACHINES Do not drive or operate any machines if your ability is affected by DOBIER S 50MG INJECTION. ALLERGY Do not receive DOBIER S 50MG INJECTION if you are allergic to Dobutamine. LUNGS DOBIER S 50MG INJECTION should be used with caution in patients with asthma or any allergic or respiratory conditions. Therefore, consult your doctor before receiving it. HEART DISEASE DOBIER S 50MG INJECTION is not recommended for use in patients who have narrowing of blood vessels supplying the heart (coronary artery stenosis) or other heart disorders. It should be used with caution in patients with other heart problems (such as coronary artery disease, or acute heart failure). Therefore, consult your doctor before receiving it. OTHERS DOBIER S 50MG INJECTION is not recommended for use if you: have low blood volume (hypovolaemia) have any disorders in the blood vessels that hinders blood flow Before receiving DOBIER S 50MG INJECTION, inform your physician if you:

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General Medicine

Dobutacan 12 Injection is a brand of Dobutamine Hydrochloride 12.5 mg/mL, a synthetic catecholamine used in critical care settings to support heart function. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dobutacan 12 Injection is indicated for: • Cardiac Decompensation: Acute heart failure due to conditions like myocardial infarction, cardiomyopathies, or post-cardiac surgery. • Cardiogenic Shock: A state of low cardiac output leading to inadequate tissue perfusion. • Septic Shock: A severe infection causing low blood pressure and organ dysfunction. • Stress Echocardiography: As a pharmacological agent to assess coronary artery disease when exercise is not feasible. It works by stimulating beta-1 adrenergic receptors, increasing heart contractility and stroke volume, thereby improving cardiac output. ________________________________________ ⚙️ Dosage and Administration Dobutacan 12 Injection is administered intravenously in a hospital setting. The typical dosage ranges from 2.5 to 10 mcg/kg/min, adjusted based on the patient's response. In some cases, doses up to 20 mcg/kg/min may be required. ________________________________________ ⚠️ Precautions and Contraindications Before using Dobutacan 12 Injection, inform your healthcare provider if you have: • Allergies to dobutamine or other components of the injection. • A history of arrhythmias or heart disease. • Kidney or liver problems. • A history of stroke or blood clots. This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. It is usually given as an intramuscular (IM) or intravenous (IV) injection. ________________________________________ 💊 Side Effects Common side effects may include: • Headache • Nausea or vomiting • Dizziness or lightheadedness • Injection site reactions (pain, redness, or swelling) Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.

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General Medicine

Methylene Blue Injection is a versatile medication with several clinical uses. It’s a synthetic dye that also functions as a medicinal agent, especially in emergency and critical care settings. ✅ Primary Medical Uses of Methylene Blue Injection Methemoglobinemia Treatment Main use: It rapidly treats methemoglobinemia, a condition where hemoglobin can’t carry oxygen effectively. Converts methemoglobin (Fe³⁺) back to normal hemoglobin (Fe²⁺), restoring oxygen delivery. Urinary Tract Antiseptic (rarely used today) Has mild antiseptic properties in the urinary tract when used with other agents. Ifosfamide-Induced Encephalopathy Used off-label to counteract neurotoxicity caused by the chemotherapy drug ifosfamide. Intraoperative Staining Agent Surgeons and urologists may use it to identify structures (e.g., fistulas, ureters, sentinel lymph nodes). Vasoplegic Syndrome in Cardiac Surgery (off-label) Helps raise blood pressure in cases of refractory hypotension after heart surgery, by inhibiting nitric oxide pathways. Diagnostic Aid Sometimes used to help visualize certain body structures or to test for leaks (like gastrointestinal perforations). ⚠️ Important Warnings & Precautions Serotonin Syndrome Risk: Methylene blue is a monoamine oxidase inhibitor (MAOI) — do not use with SSRIs, SNRIs, or other serotonergic drugs. G6PD Deficiency: Can cause hemolysis in people with glucose-6-phosphate dehydrogenase deficiency. Pregnancy: Generally avoided unless absolutely necessary. 💉 Side Effects Pain at the injection site Nausea, vomiting Headache, dizziness Blue or green discoloration of urine, stool, or skin (temporary and harmless) High doses: confusion, agitation, or chest pain

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Anti Emetic

What is Ondem 8mg Ondem 8mg is an antiemetic medication used to treat nausea and vomiting caused by illnesses like chemotherapy, radiation therapy, or surgery. The active component is Ondansetron, a Serotonin Receptor Antagonist. Ondansetron reduces nausea and vomiting by inhibiting Serotonin receptors in the gastrointestinal tract and brain. Ondem is widely administered for people receiving Cancer treatment or recovering from surgery, where nausea and vomiting are prevalent side effects. The medicine should be taken with caution in those with a history of cardiac issues, especially those with an electrolyte imbalance because it might cause QT prolongation (a kind of heart Arrhythmia). Furthermore, Ondem should not be used with some medications, such as Apomorphine (which is used to treat Parkinson's disease), due to the possibility of severe Hypotension (low blood pressure) and trouble maintaining consciousness. Patients should tell their doctor if they are taking any additional medicines, particularly those that impact the heart, liver, or Serotonin levels (e.g., antidepressants) because these interactions might increase the risk of side effects. Alkem Laboratories Ltd. primarily manufactures this medicine in a GMP-complaint facility. What are the benefits of Ondem 8mg Ondansetron in Ondem 8mg reduces nausea and vomiting by targeting a neurotransmitter in your body called Serotonin. Serotonin can cause nausea and vomiting, particularly in cancer treatment, following surgery, or even during pregnancy. Ondem inhibits Serotonin activity by binding to specific receptors in the brain's chemoreceptor trigger zone (CTZ), which regulates nausea and vomiting. The medication efficiently reduces nausea and the urge to vomit by preventing Serotonin from binding to these receptors. The medicine is quickly absorbed in the body, reaching its maximum concentration in around 1.5 hours. How to take Ondem 8mg Take Ondem 8mg tablets after consulting your doctor. Some general usage instructions include: The medicine is usually taken 1 hour before the treatment or as your doctor suggests. Swallow the tablet whole with water. Never crush or chew it. It can be taken with or without food. Follow the prescribed dose precisely as directed by your healthcare provider. What are the side effects of Ondem 8mg tablets Ondem 8 mg side effects include: Fatigue Headache Upset stomach Diarrhea These side effects are usually mild and temporary and tend to disappear as your body gets used to the medication. If any of these side effects continue or start to bother you, it's important to contact your healthcare provider without delay. Safety Advice Liver problemsLiver disease There is insufficient data regarding the use of Ondem 8mg in individuals with liver disease. It's crucial to get guidance from your healthcare expert before using this medication. CardiovascularKidney impairment The medication is usually safe for kidney patients when taken as advised. However, it is best to take a doctor’s advice before taking the pill. PregnancyPregnant and breastfeeding women There is limited information on the safety of Ondem tablets during pregnancy and breastfeeding. It's advisable to contact your doctor for personalized advice before using this medication in these situations. wineAvoid Alcohol should be avoided while taking Ondem, as it may worsen side effects. However, for overall health, it is not recommended to drink alcohol. Avoid taking the pill if you are allergic to Ondansartan or other ingredients.

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Cats and Dogs

Dermoscent® Massage Oil is the 1st dry oil for massage specifically formulated for animals. With a non-sticky texture enabling a pleasant and effective massage, this skincare helps relieve muscle and joint discomfort. Exclusively formulated with ingredients of 100% natural origin, Dermoscent® Massage Oil is the only massage oil dedicated to animals. This antioxidant care nourishes and helps protect the skin against free radicals, while relieving muscle and joint discomfort. It is particularly indicated for mobility disorders and osteoarthritis, relaxation or muscle stimulation (post-immobilization or post-surgery), as well as the preparation and recovery of athletic or working dogs.

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