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Eye Care

Tropind Plus is a combination ophthalmic solution containing Tropicamide 0.8% and Phenylephrine 5%. This formulation is primarily used for both diagnostic and therapeutic purposes in ophthalmology. 🩺 Primary Uses of Tropind Plus 1. Pupillary Dilation (Mydriasis): The combination of Tropicamide and Phenylephrine effectively dilates the pupil, allowing eye care professionals to conduct thorough examinations of the retina, optic nerve, and other internal structures. 2. Cycloplegia: Tropicamide paralyzes the ciliary muscle, preventing accommodation (focusing), which is useful in refractive error assessments. 3. Uveitis Management: In cases of uveitis, Tropind Plus helps alleviate pain and prevents further spasms of the eye muscles. 4. Preoperative Preparation: Before surgeries like cataract extraction or retinal procedures, dilating the pupil is essential for clear visualization of the posterior segment. 5. Retinal Imaging: Facilitates procedures such as fundus photography and optical coherence tomography (OCT) by ensuring adequate pupil dilation. ⚙️ How It Works • Tropicamide is a parasympatholytic agent that inhibits the contraction of the circular muscle and paralyzes the ciliary muscle, leading to pupil dilation and cycloplegia. Phenylephrine is a sympathomimetic drug that causes contraction of the radial muscle of the iris, contributing to pupil dilation. Together, these agents produce rapid and effective dilation of the pupil, facilitating detailed eye examinations and procedures. ⚠️ Side Effects Common side effects may include: • Eye pain or stinging • Blurred vision • Sensitivity to light (photophobia) • Allergic reactions These effects are typically temporary and resolve shortly after the examination. 🧪 Safety and Precautions • Driving and Operating Machinery: Avoid activities that require clear vision, such as driving, immediately after application, as the solution can cause temporary blurred vision. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or while breastfeeding, as safety data may be limited. • Drug Interactions: Be cautious when using Tropind Plus with certain medications, especially monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants, as interactions may occur.

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HIV/AIDS

INTRODUCTION ABALAM 600/300 is a combination of Abacavir and Lamivudine which belongs to the group of medicines called Anti-viral agents. It is used in the management of HIV infection in adults, adolescents and in children (weighing above 25 kgs). HIV (human immunodeficiency virus) infection is a viral infection that damages our immune system and weakens our body’s ability to fight against various infections. Both abacavir and lamivudine are nucleoside reverse transcriptase inhibitors. They work by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. This prevents further multiplication of viral cells within the body. Also, they can improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. ABALAM 600/300 cannot not manage HIV infection completely. It can reduce only the number of viral cells present in the body and maintains them at a lower level. During management with ABALAM 600/300 your doctor will closely monitor your body weight, blood cholesterol levels and blood sugar levels to reduce the risk of unwanted side effects. Do not take ABALAM 600/300 if you are allergic to abacavir or lamivudine. Before taking ABALAM 600/300 inform your doctor if you have diabetes or any liver (hepatitis C or B infection), kidney or heart problems. If you are already taking ABALAM 600/300 to manage hepatitis B or C infection, do not stop taking it without consulting your doctor. Even if you take ABALAM 600/300, it is important for you to follow certain measures to prevent the spread of infections to the other people (such as avoid having unprotected sexual intercourse or sharing needles or personal items like toothbrush, razors etc with other people). ABALAM 600/300 is not recommended for use in pregnant or breastfeeding women. The most common side effects of taking ABALAM 600/300 are difficulty in sleeping, increased signs of infections, nausea, stomach pain, headache, or dizziness. Consult your doctor if any of these side effects worsens. Also inform your doctor immediately if you experience severe fever with extreme tiredness, sudden changes in body weight or severe stomach pain along with dark urine after taking ABALAM 600/300. USES OF ABALAM 600/300 Manages HIV infection in adults, adolescents and in children (weighing above 25 kgs) HOW ABALAM 600/300 WORKS ABALAM 600/300 is an anti-retroviral medicine. It controls the multiplication of viral cell within the body, by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. It can also improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. DIRECTIONS FOR USE Take ABALAM 600/300 as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. ABALAM 600/300 can be taken with or without meals. Your doctor will decide the correct dose and for how long ABALAM 600/300 must be taken depending upon your age, body weight and severity of the infection. Do not stop taking ABALAM 600/300 without consulting your doctor as it may reduce its effectiveness. SIDE EFFECTS OF ABALAM 600/300 COMMON difficulty in sleeping feeling depressed headache, tiredness, dizziness nausea, diarrhoea fever, skin rash stomach pain loss of appetite irritated or runny nose hair loss UNCOMMON decrease in RBC, WBC, and platelets RARE Stop taking ABALAM 600/300 and contact your doctor immediately if you experience any of the following side effects: signs of allergic reactions (such as skin rash, fever, accompanied with sore throat, cough, nausea, vomiting, stomach pain, diarrhea, tiredness, joint pain, muscle pain, swelling of the neck, difficulty in breathing, mouth ulcers, occasional headaches, inflammation of the eye, low blood pressure, sense of tingling or numbness of hands or feet) pure red cell aplasia (failure of bone marrow to produce new red blood cells) signs of infections (such as fever, headache, stomach-ache, breathing difficulty) signs of auto-immune disorders (such as rapid or irregular heartbeat, tremor, hyperactivity, general weakness) signs of osteonecrosis (death of bone cells causing joint stiffness, pain in the hip, knee or shoulder and difficulty in moving) signs of liver problems (such as yellowing of the skin and whites of the eye, dark urine, light-coloured stools, loss of appetite, nausea, pain, tenderness on the right side of stomach) heart attack changes in body fat (such as increase fat in the shoulder and neck (buffalo hump), breast, and in the middle body or fat loss from the legs, arms, or face)

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Anti Cancer Medicine

Luprova 11.25 mg Injection belongs to the class of 'anticancer or anti-neoplastic agents', primarily used to treat prostate cancer in men, breast cancer and endometriosis in women and precocious puberty (early puberty) in children. Prostate cancer is the prostate gland's cancer (a small gland under the bladder secretes fluid that nourishes and protects sperm) found only in men. Breast cancer is a type of cancer that develops in breast cells stimulated by a female sex hormone called oestrogen. Endometriosis is a disorder in which tissue lining the uterus grows outside the uterine cavity. Precocious puberty occurs when a child's body changes into that of an adult or experiences puberty too soon. Luprova 11.25 mg Injection contains Leuprolide that belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. It is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. This process of lowering hormone levels can decrease cancer cell's growth in prostate cancer in men and shrinks endometriosis and breast cancer in women. Take Luprova 11.25 mg Injection as prescribed by your doctor. Your doctor will decide the dosage depending on your medical condition. The common side effects of Luprova 11.25 mg Injection include hot flashes, decreased sexual interest, shrinking of the testicles, breast tenderness or swelling, dizziness, headache, nausea, vomiting, diarrhoea, upset stomach and injection site pain reaction. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

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Anti Cancer Medicine

Celkeran 2mg tablet contains the active ingredient chlorambucil. It is an anti-cancer medicine that belongs to the class of medications called alkylating agents. It is used to treat Hodgkin’s disease and non-hodgkin’s lymphoma (cancers formed from cells of the lymphatic system). It is also indicated to treat chronic lymphocytic leukemia (A type of WBC cancer, where the bone marrow produces a large number of abnormal cells) and Waldenstrom’s macroglobulinemia (A rare lymphoma associated with an uncontrolled increase of B-cells, a type of white blood cell, resulting in the release of an abnormal protein into the blood.) Do not take this medicine if you are allergic to Celkeran 2mg tablet or any of the ingredients. Inform the physician about your recent vaccination history, liver problems, kidney problems, and seizures. Notify the doctor if you have had radiotherapy or chemotherapy before or recently. It is possible that the use of this medicine, particularly in the long term, may increase the risk of developing secondary blood cancer.

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Anti Cancer Medicine

Celdaz 500 Injection is a chemotherapeutic medicine used in the treatment of skin cancer. Cancer is a condition where the cells grow and reproduce uncontrollably in a specific body part. These cancerous cells can attack and destroy surrounding healthy tissue and organs. Celdaz 500 Injection is used in the treatment of metastatic malignant melanoma. It is a serious condition in which the cancer grows in melanocytes and also spreads to other parts of the body. Celdaz 500 Injection is also used as a second-line therapy in the treatment of Hodgkin’s Disease when used in combination with other approved drugs. Celdaz 500 Injection contains Dacarbazine, which belongs to the class of alkylating agents. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This helps prevent the growth and further spread of cancerous or non-cancerous cells. Celdaz 500 Injection may cause certain side effects, such as nausea, vomiting, headache, dizziness, and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Celdaz 500 Injection is a parenteral preparation. A trained healthcare professional will administer it.

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Anti Cancer Medicine

Chloramax 2mg tablet contains the active ingredient chlorambucil. It is an anti-cancer medicine that belongs to the class of medications called alkylating agents. It is used to treat Hodgkin’s disease and non-hodgkin’s lymphoma (cancers formed from cells of the lymphatic system). It is also indicated to treat chronic lymphocytic leukemia (A type of WBC cancer, where the bone marrow produces a large number of abnormal cells) and Waldenstrom’s macroglobulinemia (A rare lymphoma associated with an uncontrolled increase of B-cells, a type of white blood cell, resulting in the release of an abnormal protein into the blood.) Do not take this medicine if you are allergic to Chloramax 2mg tablet or any of the ingredients. Inform the physician about your recent vaccination history, liver problems, kidney problems, and seizures. Notify the doctor if you have had radiotherapy or chemotherapy before or recently. It is possible that the use of this medicine, particularly in the long term, may increase the risk of developing secondary blood cancer.

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General Medicine

Calciglu Injection is a medicinal formulation containing Calcium Gluconate, produced by American Remedies. It is primarily used to address conditions arising from calcium deficiencies. ________________________________________ 🩺 Uses of Calciglu Injection Calciglu Injection is administered intravenously to treat: • Hypocalcemia: Low blood calcium levels due to various causes. • Hypocalcemic Tetany: Muscle spasms or cramps resulting from low calcium levels. • Hypoparathyroidism: A condition where the parathyroid glands produce insufficient parathyroid hormone, leading to low calcium levels. • Calcium Deficiency During Pregnancy or Rapid Growth: Increased calcium requirements during these periods. • Hyperkalemia: High potassium levels in the blood, where calcium gluconate can help stabilize the heart's electrical activity. Magnesium Toxicity: Overdose of magnesium sulfate, often used in obstetric care, where calcium gluconate acts as an antidote. • Cardiac Arrest: To support heart function during resuscitation efforts. • Lead or Fluoride Poisoning: Calcium gluconate can bind to certain toxins, aiding in their removal from the body. ________________________________________ ⚠️ Precautions • Administration: Should be administered by a healthcare professional via intravenous injection. • Monitoring: Regular monitoring of calcium levels is essential to avoid complications. • Kidney Function: Use with caution in patients with renal impairment, as calcium accumulation can occur. • Drug Interactions: Inform your healthcare provider of all medications you're taking to avoid potential interactions.

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General Medicine

Methylene Blue Injection is a versatile medication with several clinical uses. It’s a synthetic dye that also functions as a medicinal agent, especially in emergency and critical care settings. ✅ Primary Medical Uses of Methylene Blue Injection Methemoglobinemia Treatment Main use: It rapidly treats methemoglobinemia, a condition where hemoglobin can’t carry oxygen effectively. Converts methemoglobin (Fe³⁺) back to normal hemoglobin (Fe²⁺), restoring oxygen delivery. Urinary Tract Antiseptic (rarely used today) Has mild antiseptic properties in the urinary tract when used with other agents. Ifosfamide-Induced Encephalopathy Used off-label to counteract neurotoxicity caused by the chemotherapy drug ifosfamide. Intraoperative Staining Agent Surgeons and urologists may use it to identify structures (e.g., fistulas, ureters, sentinel lymph nodes). Vasoplegic Syndrome in Cardiac Surgery (off-label) Helps raise blood pressure in cases of refractory hypotension after heart surgery, by inhibiting nitric oxide pathways. Diagnostic Aid Sometimes used to help visualize certain body structures or to test for leaks (like gastrointestinal perforations). ⚠️ Important Warnings & Precautions Serotonin Syndrome Risk: Methylene blue is a monoamine oxidase inhibitor (MAOI) — do not use with SSRIs, SNRIs, or other serotonergic drugs. G6PD Deficiency: Can cause hemolysis in people with glucose-6-phosphate dehydrogenase deficiency. Pregnancy: Generally avoided unless absolutely necessary. 💉 Side Effects Pain at the injection site Nausea, vomiting Headache, dizziness Blue or green discoloration of urine, stool, or skin (temporary and harmless) High doses: confusion, agitation, or chest pain

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General Medicine

Atranium 50 mg Injection is a neuromuscular blocking agent containing Atracurium Besylate. It is primarily used in medical settings to facilitate muscle relaxation during surgical procedures and in intensive care units (ICU) for patients requiring mechanical ventilation. ________________________________________ 🩺 Uses of Atranium 50 mg Injection • General Anesthesia: Atranium is administered to relax skeletal muscles during surgeries, aiding in endotracheal intubation and ensuring muscle immobility. • Intensive Care Unit (ICU): It assists in controlled ventilation for ICU patients who need mechanical support for breathing. ________________________________________ 💊 Mechanism of Action Atranium works by blocking the transmission of nerve impulses to skeletal muscles, leading to muscle relaxation. This effect is crucial during surgeries and in ICU settings where muscle control is necessary for patient management. ________________________________________ ⚠️ Side Effects Common side effects may include: • Flushing or redness of the skin • Itching or rash • Injection site reactions (pain, swelling, or redness) • Wheezing or bronchospasm • Rapid heart rate (tachycardia) These side effects are generally mild and transient. However, if they persist or worsen, consult your healthcare provider. ________________________________________ 💰 Price and Availability The price of Atranium 50 mg Injection varies by retailer. For instance, it is available for ₹51.22 per 5 ml vial at Truemeds . Prices can differ based on location and pharmacy. ________________________________________ ⚠️ Precautions Before using Atranium 50 mg Injection, inform your doctor if you: • Have a history of allergies to atracurium or other neuromuscular blocking agents. • Have conditions such as myasthenia gravis, Eaton-Lambert syndrome, or severe electrolyte imbalances. • Are pregnant, planning to become pregnant, or breastfeeding. • Are taking other medications, including over-the-counter drugs and supplements.

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