Wholesale Olaparib 150mg USA | Certified Indian Pharmaceutical Exporter | Ernest Impex

BRCAONE 150mg Tablet: Advanced PARP Inhibitor Therapy

Are you seeking a dependable BRCAONE 150 mg tablet exporter from India? Ernest Impex, an integral division of the Group of Ernest Pharmaceutical Pvt. Ltd., is a global leader in the wholesale distribution of specialized oncology and critical care formulations. We provide robust, GDP-compliant supply chains and secure logistics to Washington (USA), London (UK), Bangkok (Thailand), Canberra (Australia), Singapore, and Kingston (Jamaica).

Extensive Product Profile: Understanding BRCAONE 150mg Tablet

BRCAONE 150mg Tablet contains Olaparib, an advanced targeted cancer medication that acts as a PARP (poly [ADP-ribose] polymerase) inhibitor. It is manufactured to the highest global pharmaceutical standards and is widely indicated for patients with specific BRCA-mutated or advanced malignancies.

1. Clinical Indications & Usage

BRCAONE 150 mg Tablet is formulated for:

• Ovarian and Breast Cancer: Indicated for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer, and for HER2-negative metastatic breast cancer.

• Prostate and Pancreatic Cancer: Used in patients with deleterious or suspected deleterious germline BRCA-mutated metastatic pancreatic and castration-resistant prostate cancer.

2. Mechanism of Action

BRCAONE 150mg Tablet acts through a highly specific pharmacological pathway:

• PARP Inhibition: Olaparib blocks the PARP enzymes (PARP1, PARP2, and PARP3), which are vital for repairing single-strand DNA breaks.

• Synthetic Lethality: In cancer cells that already have deficiencies in the BRCA 1 or 2 genes (homologous recombination deficiency), the combination of BRCA mutations and PARP inhibition creates irreparable DNA damage, leading to cell cycle arrest and apoptosis.

3. Administration and Dosing Guide

• Administration Route: Administered orally. Tablets should be swallowed whole with water; do not crush, chew, break, or split.

• Precaution: Grapefruit, Seville oranges, and their juices may interact with Olaparib and alter its therapeutic levels.

• Contraindications: Highly unsafe during pregnancy; women and male partners of reproductive potential must use highly effective contraception during treatment and for several months afterward.

Safety, Side Effects, and Monitoring

BRCAONE 150mg Tablet is a potent clinical formulation and requires medical supervision:

• Hematologic Monitoring: Routine assessment of complete blood count (CBC) is necessary due to the risk of anemia, neutropenia, and thrombocytopenia.

• Common Side Effects: Nausea, vomiting, diarrhea, fatigue, headache, changes in taste (dysgeusia), and dizziness.

• Toxicity Management: Patients must be monitored for signs of myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML), as well as pneumonitis.

Storage Requirements

• Storage Conditions: Do not store above $30^\circ\text{C}$. Keep the product in its original, closed packaging.

• Protection: Store away from heat, moisture, and direct light. Do not freeze.

• Safety: Keep out of reach of children and pets.

Why Partner with Ernest Impex for Global Sourcing?

Sourcing through Ernest Impex ensures you receive professional-grade, secured supply-chain services:

• Traceability: Every shipment is provided with a full Certificate of Analysis (COA) and complete batch traceability.

• Regulatory Support: We facilitate document clearance and supply chain logistics in compliance with TGA, HSA, and US-FDA/MHRA guidelines.

• Temperature Integrity: Handled and shipped under strict environmental monitoring to prevent degradation from temperature variations or light exposure.

• Secure Bulk Supply: Consistent inventory availability for institutional healthcare tenders, pharmacies, and specialty clinics.

Sales, Pricing, and Market Insights

• B2B / Wholesale Price Range: Bulk procurement prices for verified Indian manufacturers and distributors range from ₹35,000 to ₹40,723 per pack of 60 tablets depending on volume, destination country, and export taxes.

• Product Form: Oral tablets, 60 tablets per container.