Abevmy 400mg Injection
Jamaica – Kingston (PERU , BRAZIL , PARAGUAY , MEXICO , CHILE, COLOMBIA , ARGENTINA )
Generic Name: Bevacizumab (400mg)
Storage: Store in a refrigerator (2°C – 8°C). Do not freeze.
Product Description
Abevmy 400mg Injection is a monoclonal antibody-based anticancer medication containing Bevacizumab (400mg) as its active ingredient. It is used in the treatment of various types of cancers, including colorectal cancer, non–small cell lung cancer, kidney cancer, brain tumors, ovarian cancer, and cervical cancer.
Abevmy acts by inhibiting vascular endothelial growth factor (VEGF) — a protein that stimulates the formation of new blood vessels (angiogenesis). By blocking VEGF, the medicine restricts the blood supply that supports tumor growth, thereby inhibiting cancer progression and enhancing the efficacy of other anticancer therapies.
Therapeutic Indications
Abevmy 400mg Injection is indicated for use in combination with other chemotherapy agents for the treatment of:
Metastatic colorectal cancer
Non–small cell lung cancer (NSCLC)
Renal cell carcinoma
Glioblastoma (brain tumor)
Epithelial ovarian, fallopian tube, or primary peritoneal cancer
Cervical cancer
Dosage and Administration
Abevmy 400mg Injection is administered as an intravenous infusion under the supervision of a qualified healthcare professional.
The dosage and treatment duration are individualized based on the patient’s condition and response.
The first infusion is administered slowly to monitor for infusion-related reactions such as elevated blood pressure or breathing difficulty.
Treatment is continued as long as clinical benefit persists and side effects remain manageable.
Mechanism of Action
Bevacizumab is a humanized monoclonal antibody that targets and neutralizes VEGF-A, a signaling protein responsible for angiogenesis. By preventing VEGF from binding to its receptors on the surface of endothelial cells, Abevmy inhibits the formation of new blood vessels, depriving tumors of oxygen and nutrients essential for growth.
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Side effects of Abevmy Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Abevmy
Nosebleeds
Headache
High blood pressure
Inflammation of the nose
Protein in urine
Taste change
Dry skin
Hemorrhage
Increased lacrimation
Back pain
Exfoliative dermatitis
Precautions & Warnings
Surgery: Abevmy may impair wound healing; discontinue treatment before elective surgery and resume only after adequate healing.
Bleeding Risk: Increases susceptibility to bleeding; caution advised in patients with recent surgery or bleeding disorders.
Pregnancy & Lactation: Contraindicated during pregnancy and breastfeeding unless clearly necessary. It may cause harm to the fetus or pass into breast milk.
Driving: May cause dizziness or fainting; patients should avoid driving or operating machinery if affected.
Renal & Hepatic Impairment: Generally safe with no dosage adjustment required; however, close monitoring is recommended.
Storage Instructions
Store in a refrigerator (2°C – 8°C).
Do not freeze or shake the vial.
Protect from light and keep out of reach of children.
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Key Highlights
Category: Oncology / Anti-angiogenic agent
Form: Concentrate for solution for infusion
Strength: 400mg/16mL vial (25mg/mL)
Route of Administration: Intravenous infusion only
