Hyperphosphatemia or high phosphorus levels in the blood is one of the most common conditions during the progression of kidney disease in dogs and cats. Phosphate binders are medications used to reduce the absorption of dietary phosphate. Sevelamer carbonate is a calcium-free, aluminium-free, non-metal phosphate binder for dogs & cats. Phoslure treats hyperphosphatemia in patients with chronic kidney disease without the risk of hypercalcemia or aluminium toxicity. It significantly slows the progression of vascular calcification as compared to calcium-phosphate binders and reduces cardiovascular morbidity and mortality.

Taurians contains 2 potent anti-oxidants – N-acetyl cysteine & Taurine. Taurine is an amino acid that both dogs and cats require for good health. For cats, taurine is necessary for brain, nerves, eyes, heart, digestion, immune function and fetal development. For dogs, taurine is needed for eyes, reproduction, bile acid (for fat digestion) and for healthy heart. N-Acetylcysteine is useful in treating conditions that involve tissue damage due to oxidative stress and toxicity, Taurians helps to protect against damage from oxidative stress in patients with chronic kidney disease, reduces risk of cardiovascular disease, promotes healthy liver, prevents or reduces glomerular damage due to diabetes, and promotes clean & healthy lungs.

Research has shown that nutritional modifications can slow the progression of cardiac disease and improve quality of life of companion animals. Strongbeat is a unique formula that contains amino acids, vitamins, minerals and anti-oxidants that provide energy & strengthen heart muscle function in pets. Strongbeat can be used in dogs and cats with pre-existing suboptimal cardiovascular functions, in breeds that are predisposed to cardiovascular stress and to support the heart in geriatric or older patients.

Biotrav-T (Travoprost and Timolol Maleate) Ophthalmic Solution is a prescription eye drop used to manage elevated intraocular pressure (IOP) in individuals with open-angle glaucoma or ocular hypertension. It combines two medications—travoprost (a prostaglandin analog) and timolol maleate (a non-selective beta-blocker)—to reduce IOP through complementary mechanisms. ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common form of glaucoma characterized by gradual loss of vision due to increased IOP. • Ocular Hypertension: Elevated IOP without optic nerve damage, which can lead to glaucoma if untreated. ________________________________________ 💊 Dosage and Administration • Recommended Dosage: Instill one drop into the affected eye(s) once daily, preferably in the evening. • Application Tips: o Wash hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Active or suspected ocular infections. o History of hypersensitivity to beta-blockers. • Cautions: o Use with caution in patients with cardiovascular or pulmonary diseases, as timolol may exacerbate conditions like asthma, bradycardia, or heart block. o Monitor for potential systemic absorption effects, including hypotension or bradycardia. o Consult a healthcare provider before use if pregnant, planning to become pregnant, or breastfeeding. ________________________________________

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

Nitrocan 25 Injection is a brand of Nitroglycerin Injection 25 mg/5 mL, manufactured by American Remedies. It is primarily used in hospital settings for the management of certain cardiovascular conditions. ________________________________________ ✅ Primary Uses Nitrocan 25 Injection is indicated for: • Angina Pectoris: To treat and prevent chest pain caused by reduced blood flow to the heart. • Acute Myocardial Infarction (Heart Attack): To alleviate chest pain and improve blood flow to the heart muscle. Hypertension During Surgery: To control high blood pressure during and after surgical procedures. • Congestive Heart Failure: To reduce the workload on the heart and improve symptoms. ________________________________________ ⚙️ Mechanism of Action Nitroglycerin is a nitrate that, once administered, is converted into nitric oxide in the body. This leads to the relaxation and dilation of blood vessels, improving blood flow and reducing the heart's workload. ________________________________________ ⚠️ Precautions • Contraindications: Should not be used in patients with severe anemia, hypotension, or those taking medications for erectile dysfunction (e.g., sildenafil, tadalafil) due to the risk of a significant drop in blood pressure. • Monitoring: Requires careful monitoring of blood pressure and heart rate during administration. • Administration: Administered intravenously under medical supervision; dosage and duration are determined by the healthcare provider. ________________________________________ 💊 Common Side Effects • Headache • Dizziness or lightheadedness • Hypotension (low blood pressure) • Nausea or vomiting • Flushing

Milrican 10 is a brand of Milrinone Lactate Injection, manufactured by American Remedies. Milrinone is a phosphodiesterase-3 (PDE3) inhibitor that serves as both an inotropic agent and a vasodilator. ________________________________________ ✅ Primary Uses of Milrican 10 Milrican 10 is indicated for the short-term intravenous treatment of: • Severe congestive heart failure: Particularly in patients unresponsive to conventional therapies. • Acute decompensated heart failure: Including low output states following cardiac surgery. It is commonly used in intensive care units or during cardiac procedures to support heart function. ________________________________________ ⚙️ Mechanism of Action Milrinone works by inhibiting PDE3, leading to increased cyclic AMP (cAMP) levels in cardiac and vascular smooth muscle cells. This results in: • Increased myocardial contractility: Enhancing the heart's ability to pump blood. • Vasodilation: Relaxing blood vessels, which reduces the heart's workload and improves blood flow. ________________________________________ ⚠️ Important Considerations • Administration: Milrican 10 should only be administered intravenously under the supervision of a healthcare professional. • Monitoring: Patients receiving Milrican 10 require close monitoring of blood pressure, heart rate, and kidney function. • Contraindications: Not recommended for patients with severe dehydration, electrolyte imbalances, or known hypersensitivity to milrinone. • Pregnancy and Breastfeeding: Consult a doctor before use if pregnant or breastfeeding.

Labecanol Injection 4 ml belongs to the group of anti-hypertensive medicines called beta-blocking agents used to treat severe hypertension (high blood pressure). Additionally, American Labecanol Injection 4 ml is used to control high blood pressure in pregnancy and during anaesthesia. Labecanol Injection 4 ml contains ‘labetalol’ that works by blocking the receptors in the cardiovascular (circulatory) system, this helps in decreasing the blood pressure in the blood vessels. Thus, it helps lower the blood pressure to normal. In some cases, American Labecanol Injection 4 ml may cause common side effects such as postural hypotension, dizziness, fatigue, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Prostal 500mcg Injection Salt Composition : Alprostadil Manufacturer : CELON LABORATORIES LTD Introduction to Prostal 500mcg Injection Prostal 500mcg injection contains active components called Alprostadil. This medication is often used to treat ED in men with difficulty achieving or maintaining an erection. It may be used to improve blood flow in patients with peripheral arterial disease (PAD), a condition in which blood flow to the extremities (usually the legs) is reduced. In newborns with certain heart conditions, such as PDA, it can open a blood vessel called the ductus arteriosus. It can also be used in diagnostic tests to assess blood flow in specific body areas, such as during penile Doppler ultrasound studies to evaluate erectile function. Individuals who have a known allergy or hypersensitivity to Alprostadil or any of its components should not use the medication. It should be avoided in men with penile implants or conditions that make penile injections unsafe, such as penile fibrosis, curvature, or priapism (prolonged erections). It should not be used in individuals with conditions predisposing them to priapism, such as sickle cell anemia, multiple myeloma, or leukemia. It should not be used in individuals who experience unexplained genital or pelvic pain, as it may indicate an underlying medical condition. Individuals with bleeding disorders or those taking anticoagulant medications (blood thinners) should use Prostal 500mcg injection cautiously, as it may increase the risk of bleeding at the injection site. It should not be used concomitantly with alpha-blocker medications used to treat conditions like benign prostatic hyperplasia (BPH) and high blood pressure, as it can lead to severe low blood pressure. It should not be used in infants with congenital heart defects who have conditions that are worsened by increased blood flow to the lungs. It can be used in elderly patients, but caution may be required. Uses of Prostal 500mcg Injection Erectile dysfunction (ED) Peripheral arterial disease (PAD) Patent ductus arteriosus (PDA) in Infants Diagnostic testing Therapeutic Effects of Prostal 500mcg Injection Prostal 500mcg injection binds to specific receptors on smooth muscle cells in blood vessels and various tissues. When it binds to these receptors, it triggers biochemical events that lead to vasodilation. It relaxes the smooth muscles in blood vessel walls, particularly in the penis, when used for erectile dysfunction. It involves promoting the relaxation of smooth muscle cells, improving blood flow to specific body areas, depending on its intended use. Interaction of Prostal 500mcg Injection with other drugs Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Prostal 500mcg injection, reducing effectiveness by causing undesirable side effects. More Information about Prostal 500mcg Injection Store at room temperature below 20 to 25°C Keep away from moisture, heat, and light. It should not be frozen. Keep away from children and pets. How to consume Prostal 500mcg Injection Prostal 500mcg injection can be administered via various routes, depending on the medical condition. For erectile dysfunction (ED), it can be injected directly into the penis (intracavernosal injection), applied topically to the penile tip (urethral application), or used as a urethral suppository. Safety Advices for Prostal 500mcg Injection Image Not Available Pregnancy If you are pregnant or trying to become pregnant, it is important to talk to your doctor before taking Prostal 500mcg injection. Image Not Available Breast Feeding There is limited research on the safety of Prostal 500mcg injection in breastfeeding women. It is important to talk to your doctor before taking this medication. Image Not Available Lungs If you have lung diseases, talking to your doctor before taking Prostal 500mcg injection is important. Image Not Available Liver Prostal 500mcg injection is metabolized in the liver, so individuals with severe liver disease may require dose adjustments. Patients with liver problems should discuss their condition with their healthcare provider before using it. Image Not Available Alcohol It is unsafe to drink alcohol while taking Prostal 500mcg injection. Excessive alcohol consumption can increase the risk of certain side effects. Image Not Available Driving Prostal 500mcg injection can cause dizziness or fainting, especially if low blood pressure occurs. If you experience any side effects, consult your healthcare provider before taking it while driving. Side Effects of Prostal 500mcg Injection Prostal 500mcg injection causes some side effects like all medications, although not everyone will experience them. Serious: Priapism Penile fibrosis Allergic reactions Low blood pressure Cardiovascular effects Bleeding Common: