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'severe systemic infection'

Items tagged with 'severe systemic infection'

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General Medicine

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

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Heart Disorder

Adrenor 4mg Injection Salt: Noradrenaline (4mg/2ml) Description Adrenor 4mg Injection is used to treat hypotension (low blood pressure) that may occur due to causes such as sepsis (infection). It helps to increase blood pressure by narrowing the blood vessels of the heart. It may be used to revive a patient with cardiac arrest. Adrenor 4mg Injection is used to treat hypotension (low blood pressure) that may occur due to causes such as sepsis (infection). It helps to increase blood pressure by narrowing the blood vessels of the heart. It may be used to revive a patient with cardiac arrest. Adrenor 4mg Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. Doctor may closely monitor your blood pressure and heart rate till you became stable. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. Your doctor may advise for regular monitoring of blood pressure. It may cause side effects like high blood pressure, headache, and insomnia (difficulty in sleeping). You must inform the doctor if you are suffering from diabetes, liver, heart or kidney disease. Also, let your doctor know about all the other medications that you are using regularly. This medicine is not usually recommended during pregnancy or breastfeeding, so always consult your doctor before taking it. Benefits 1. In Low blood pressure: Adrenor 4mg Injection is used to normalise decreased blood pressure (hypotension) which may occur all of a sudden during an operation, severe infection (sepsis) or due to an emergency condition (cardiac arrest). This medicine helps to bring back the blood pressure within normal range and therefore prevents any sudden fall or even serious complications that might have otherwise followed due to low blood pressure. Side Effects Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Common side effects of Adrenor: - Systemic hypertension (high blood pressure) - Headache - Restlessness - Insomnia (difficulty in sleeping) - Palpitations - Tremor.

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Heart Disorder

Norbit Injection Marketer Celon Laboratories Ltd SALT COMPOSITION Norepinephrine (2mg) Storage Store below 30°C Uses of Norbit Injection Low blood pressure Severe allergic reactions Glaucoma Decreased blood pressure Local anesthesia (Numb tissues in a specific area) Bleeding Allergic conditions Cardiac arrest Product introduction Norbit Injection is used to treat hypotension (low blood pressure) that may occur due to causes such as sepsis (infection). It helps to increase blood pressure by narrowing the blood vessels of the heart. It may be used to revive a patient with cardiac arrest. Norbit Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. Doctor may closely monitor your blood pressure and heart rate till you became stable. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. Your doctor may advise for regular monitoring of blood pressure. It may cause side effects like high blood pressure, headache, and insomnia (difficulty in sleeping). You must inform the doctor if you are suffering from diabetes, liver, heart or kidney disease. Also, let your doctor know about all the other medications that you are using regularly. This medicine is not usually recommended during pregnancy or breastfeeding, so always consult your doctor before taking it. Benefits of Norbit Injection In Low blood pressure Norbit Injection is used to normalise decreased blood pressure (hypotension) which may occur all of a sudden during an operation, severe infection (sepsis) or due to an emergency condition (cardiac arrest). This medicine helps to bring back the blood pressure within normal range and therefore prevents any sudden fall or even serious complications that might have otherwise followed due to low blood pressure. Side effects of Norbit Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Norbit Systemic hypertension (high blood pressure) Headache Restlessness Insomnia (difficulty in sleeping) Palpitations Tremors How to use Norbit Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Norbit Injection works NA. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Norbit Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Norbit Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Norbit Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. warnings Driving NOT RELEVANT Not relevant, as Norbit Injection is intended for use in hospitalised patients. warnings Kidney CONSULT YOUR DOCTOR There is limited information available on the use of Norbit Injection in patients with kidney disease. Please consult your doctor. warnings Liver CONSULT YOUR DOCTOR There is limited information available on the use of Norbit Injection in patients with liver disease. Please consult your doctor.

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General Medicine

Cortican 100 Injection is a corticosteroid medication containing hydrocortisone, primarily used to treat various inflammatory and allergic conditions. It is administered under medical supervision and is not intended for self-administration. ________________________________________ 🩺 Primary Uses Cortican 100 Injection is employed in the management of: • Severe allergic reactions: Including anaphylaxis and status asthmaticus (severe asthma attacks). • Autoimmune disorders: Such as systemic lupus erythematosus (SLE) and Stevens-Johnson syndrome. • Inflammatory conditions: Including ulcerative colitis, Crohn’s disease, and rheumatoid arthritis. • Joint and tendon inflammations: Conditions like tennis elbow and bursitis. • Adrenal insufficiency: As a replacement therapy for cortisol in conditions like Addison’s disease. • Severe infections or trauma: To manage shock and inflammation resulting from infections or injuries. ________________________________________ ⚙️ Mechanism of Action Hydrocortisone, the active ingredient in Cortican 100, functions by: • Inhibiting the release of substances that cause inflammation, redness, and swelling. • Suppressing the immune system to reduce autoimmune reactions. • Replacing cortisol in the body when adrenal glands do not produce sufficient amounts. ________________________________________ ⚠️ Administration & Safety • Cortican 100 Injection should be administered by a healthcare professional. • It is typically given via intramuscular (IM), intravenous (IV), or intra-articular (joint) injection. • Patients should not self-administer this medication. • Before receiving this injection, inform your doctor if you have any infections, are pregnant or breastfeeding, or have been recently vaccinated. ________________________________________ ⚠️ Side Effects Common side effects may include: • Acne and increased hair growth. • Weight gain and fluid retention. • Dizziness, nausea, and indigestion. • Mood changes, including depression

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General Medicine

Clocivir 500 Injection is an intravenous formulation containing Acyclovir 500 mg, manufactured by American Remedies. It is primarily used to treat severe viral infections caused by herpes viruses. ________________________________________ 🩺 Uses of Clocivir 500 Injection Clocivir 500 Injection is indicated for: • Herpes Simplex Infections in Immunocompromised Patients: Including severe primary or non-primary genital herpes. • Herpes Simplex Encephalitis: A serious brain infection caused by the herpes simplex virus. • Neonatal Herpes Simplex Virus Infection: In newborns. • Varicella-Zoster Infections in Immunocompromised Patients: Such as severe cases of chickenpox or shingles. • Severe Herpes Zoster (Shingles): In immunocompetent patients with very severe acute local or systemic manifestations. ________________________________________ 💊 Mechanism of Action Acyclovir, the active ingredient in Clocivir, is a synthetic purine nucleoside analogue. It exerts its antiviral effects by inhibiting viral DNA synthesis, thereby preventing the replication of herpes viruses. Acyclovir is converted to its active form, Acyclovir Triphosphate, within infected cells, which then interferes with viral DNA polymerase. ________________________________________ ⚠️ Precautions • Administration: Clocivir 500 Injection should be administered by a healthcare professional through slow intravenous infusion over a 1-hour period to minimize the risk of kidney damage. • Hydration: Adequate hydration is essential during treatment to prevent dehydration and kidney damage. • Kidney Function: Use with caution in patients with pre-existing kidney conditions. • Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

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Antiparasitic Medicines

Albendazole and Ivermectin are antiparasitic medications that are often combined in a single tablet to treat a wide range of parasitic infections in the body. 🧬 Combined Uses of Albendazole + Ivermectin Tablet: This combination is commonly used to treat: 🔹 Intestinal Worms: Roundworms (Ascaris) Pinworms (Enterobius) Hookworms (Ancylostoma, Necator) Whipworms (Trichuris) 🔹 Tissue and Systemic Parasitic Infections: Neurocysticercosis (Albendazole is key for brain cysts caused by pork tapeworm) Strongyloidiasis Cutaneous larva migrans (creeping skin eruption from hookworm larvae) Filariasis (Ivermectin especially) 🔹 Scabies & Lice (Ivermectin): Though more commonly treated with topical forms, oral ivermectin is sometimes used for severe or resistant cases.

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