Marketer Cipla Ltd SALT COMPOSITION Abiraterone Acetate (250mg) Storage Store below 30°C Uses of Xbira Tablet Sickle cell anemia Prostate cancer Blood cancer (Acute lymphocytic leukemia) Soft tissue sarcoma Hodgkin’s disease Product introduction Xbira 250mg Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy. Xbira 250mg Tablet should not be taken on an empty stomach. Taking it with food may cause side effects. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, fatigue and increased liver enzymes. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Other than this, yellowing of skin, loss of appetite, shortness of breath, dark urine and nausea can happen, which indicate some liver problem. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood. Before taking it, tell your doctor if have high blood pressure, heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment. There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details. Side effects of Xbira Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Xbira Edema (swelling) Vomiting Decreased potassium level in blood Fatigue Anemia (low number of red blood cells) Urinary tract infection Diarrhea High blood pressure Cough Joint swelling How to use Xbira Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xbira 250mg Tablet is to be taken empty stomach. How Xbira Tablet works Xbira 250mg Tablet is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.

Marketer Cipla Ltd SALT COMPOSITION Abiraterone Acetate (500mg) Storage Store below 30°C Uses of Xbira Tablet Sickle cell anemia Prostate cancer Blood cancer (Acute lymphocytic leukemia) Soft tissue sarcoma Hodgkin’s disease Product introduction Xbira 500 Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy. Xbira 500 Tablet should not be taken on an empty stomach. Taking it with food may cause side effects. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, fatigue and increased liver enzymes. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Other than this, yellowing of skin, loss of appetite, shortness of breath, dark urine and nausea can happen, which indicate some liver problem. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood. Before taking it, tell your doctor if have high blood pressure, heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment. There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details. Side effects of Xbira Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Xbira Edema (swelling) Vomiting Decreased potassium level in blood Fatigue Anemia (low number of red blood cells) Urinary tract infection Diarrhea High blood pressure Cough Joint swelling How to use Xbira Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xbira 500 Tablet is to be taken empty stomach. How Xbira Tablet works Xbira 500 Tablet is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.

Marketer BDR Pharmaceuticals Internationals Pvt SALT COMPOSITION Enzalutamide (80mg) Storage Store below 30°C Uses of BDENZA Capsule Prostate cancer Polycystic ovarian syndrome (PCOS) Excessive hair growth Product introduction BDENZA 80 Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone. BDENZA 80 Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, fractures, falls, dry skin, pruritus,decreased appetite, and constipation might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out. Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment. Side effects of BDENZA Capsule Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of BDENZA Headache Hot flashes Weakness High blood pressure Fatigue Decreased appetite Constipation Dry skin Itching Fall Fracture How to use BDENZA Capsule Take this medicine in the dose and duration as advised by your doctor. BDENZA 80 Capsule may be taken with or without food, but it is better to take it at a fixed time. How BDENZA Capsule works BDENZA 80 Capsule is an antiandrogens. It works by blocking the effect of the natural male hormones on the growth of prostate cells.

Marketer BDR Pharmaceuticals Internationals Pvt SALT COMPOSITION Rucaparib (300mg) Uses of Bdparib Tablet Sickle cell anemia Ovarian cancer Prostate cancer Blood cancer (Acute lymphocytic leukemia) Soft tissue sarcoma Hodgkin’s disease Product introduction Bdparib 300 Tablet is used in the treatment of prostate and ovarian cancers. It works by stopping the repair of damaged cancer cells, which stops their further growth, and kills the damaged cancer cells. Bdparib 300 Tablet can be taken with or without food, but better to have it at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as advised by the doctor. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include increased liver enzymes, decreased appetite, anemia, weakness, gastrointestinal disturbance, acute myeloid leukemia (blood cancer), and nasopharyngitis (inflammation of the throat and nasal passages). Inform your doctor if you notice fever, chills, sore throat, and severe diarrhea. Regular blood tests are required to check your blood cells along with the heart, liver, and blood uric acid levels. It is advised to stay hydrated while taking this medicine to overcome diarrhea. Before taking it, tell your doctor if you have heart disease, liver or kidney problems, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine, so let your healthcare team know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Effective contraception by both males and females during the treatment is important to avoid pregnancy. Benefits of Bdparib Tablet In Ovarian cancer Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Bdparib 300 Tablet kills the cancer cells and also prevents the repair of damaged cancer cells. It is an effective medicine but has some side effects that may be bothersome. Consult your doctor to know about the ways that can help you avoid these side effects. Side effects of Bdparib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Bdparib Nasopharyngitis (inflammation of the throat and nasal passages) Rash Increased liver enzymes Decreased appetite Anemia (low number of red blood cells) Weakness Gastrointestinal disturbance Myelodysplastic syndrome Acute myeloid leukemia (blood cancer) How to use Bdparib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bdparib 300 Tablet may be taken with or without food, but it is better to take it at a fixed time. How Bdparib Tablet works Bdparib 300 Tablet prevents (by blocking certain proteins) cancer cells from repairing their damaged DNA, causing them to die. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Bdparib 300 Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Bdparib 300 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Marketer Getwell Pharma (I) Pvt Ltd SALT COMPOSITION Docetaxel (20mg) Storage Store in a refrigerator (2 - 8°C). Do not freeze. Uses of Taxewell Injection Breast cancer Non-small cell lung cancer Prostate cancer Cancer of head and neck Product introduction Taxewell 20mg Injection is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of head and neck. Taxewell 20mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Some of the common side effects of this medicine include breathlessness, constipation, edema (swelling), infection, loss of appetite, muscle pain, nail disorder, pain, and weakness. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function. Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine. Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Benefits of Taxewell Injection In Breast cancer Taxewell 20mg Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Taxewell 20mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you. In Non-small cell lung cancer Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Taxewell 20mg Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated. In Prostate cancer Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Taxewell 20mg Injection decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate. In Cancer of head and neck Head and neck cancer includes cancer of the mouth, nose, sinuses or throat. Taxewell 20mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but it has some bothersome side effects. Therefore, you should discuss the risks and benefits with your doctor.

Marketer Getwell Pharma (I) Pvt Ltd SALT COMPOSITION Asparaginase (10000IU) Storage Store in a refrigerator (2 - 8°C). Do not freeze. Uses of L Ginase Injection Sickle cell anemia Prostate cancer Blood cancer (Acute lymphocytic leukemia) Soft tissue sarcoma Hodgkin’s disease Product introduction L Ginase 10000IU Injection is used in the treatment of some kinds of cancer of white blood cells (leukemia). It may also be used to treat other types of cancer as determined by your doctor. It may be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy. L Ginase 10000IU Injection is given as an injection by the doctor, but try to have it the same time each day to make sure it has the best effect. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effect of this medicine includes breathlessness, rash, vomiting, angioedema (swelling of deeper layers of skin), and nausea. It might cause increased blood sugar levels, hence regular blood tests are required to monitor your blood sugar levels, response to the therapy, and any side effects. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well. This medicine may lower your body's resistance and increase susceptibility to infections. Infections can sometimes be life-threatening. It is important to use effective contraception to avoid getting pregnant or fathering a child during treatment. Before taking this medicine, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Side effects of L Ginase Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of L Ginase Breathlessness Rash Vomiting Angioedema (swelling of deeper layers of skin) Edema (swelling) Nausea Fatigue Increased liver enzymes Diarrhea Decreased blood pressure Flushing (sense of warmth in the face, ears, neck and trunk) Low albumin level in blood Increased glucose level in blood Hives

Marketer Getwell Pharma (I) Pvt Ltd SALT COMPOSITION Epirubicin (50mg) Storage Store in a refrigerator (2 - 8°C). Do not freeze. Uses of Epiruba Injection Cancer Breast cancer Non-small cell lung cancer Prostate cancer Cancer of head and neck Stomach cancer Pancreatic cancer Testicular cancer Small cell lung cancer Wilms' tumor Bone cancer Gestational trophoblastic neoplasia Blood cancer Skin cancer Cancer of mouth, nasopharynx and paranasal sinuses, larynx, oesophagus Cervical cancer Ovarian cancer Ewing's sarcoma Product introduction Epiruba 50mg Injection is used in the treatment of various types of cancers of blood, breast, stomach, lung, ovaries and soft tissues. It also helps to prevent the recurrence of bladder cancer after surgery. It is given as a drip or infusion vein with extreme caution by a qualified medical professional. It can be used alone, or sometimes given together with certain other medicines as part of combination chemotherapy. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to both male and female to use reliable contraception during the treatment. The most common side effects of this medicine include nausea, low blood platelets, hair loss, absence of menstrual periods, fever and rash. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Infections can sometimes be life threatening. Regular blood tests are required to monitor your blood cells along with kidney, liver and heart function during treatment with this medicine. Before taking this medicine, tell your doctor if you have liver disease, or have heart problem. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant or breastfeeding. Benefits of Epiruba Injection In Cancer Epiruba 50mg Injection helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Epiruba 50mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated. Side effects of Epiruba Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Epiruba Low blood platelets Nausea Hair loss Absence of menstrual periods Fever Anemia (low number of red blood cells) Diarrhea Weight loss Decreased white blood cell count (neutrophils) Hot flashes Gastrointestinal inflammation Rash Low energy Eye disorder How to use Epiruba Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Epiruba Injection works Epiruba 50mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the breast cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of breast cancer cells and eventually kills them.

Marketer Halsted Pharma Private Limited SALT COMPOSITION Dactinomycin (0.5mg) Storage Store below 30°C Uses of Dacihal Injection Breast cancer Non-small cell lung cancer Prostate cancer Cancer of head and neck Stomach cancer Pancreatic cancer Testicular cancer Small cell lung cancer Wilms' tumor Bone cancer Gestational trophoblastic neoplasia Blood cancer Skin cancer Cancer of mouth, nasopharynx and paranasal sinuses, larynx, oesophagus Cervical cancer Ovarian cancer Ewing's sarcoma Product introduction Dacihal Injection 0.5mg is used for the treatment of several kinds of cancer such as some kinds of cancer that affect the testicles (testicular cancer), uterus or womb (gestational trophoblastic neoplasia), kidneys (Wilms' tumor), bones and muscles (Ewing's sarcoma). Dacihal Injection 0.5mg works by interfering with the growth of cancer cells, which are eventually destroyed. It is given under the supervision of a healthcare professional and should not be self-administered. It might be given as a single therapy or in combination with some other medication. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage. The most common side effects of this medicine include nausea, vomiting, mouth ulcers and loss of appetite. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these. Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, and physical examinations both before and during treatment with this medicine. Side effects of Dacihal Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Dacihal Nausea Vomiting Loss of appetite Glossitis (tongue inflammation) Lip inflammation Diarrhea Inflammation of the rectum Low blood platelets How to use Dacihal Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Dacihal Injection works Dacihal Injection 0.5mg is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Marketer Cipla Ltd SALT COMPOSITION Relugolix (120mg) Storage Store below 30°C Uses of Xelucip Tablet Treatment of Advanced Prostate cancer Product introduction Xelucip Tablet is a medicine used in the treatment of advanced prostate cancer. It works by lowering the amount of testosterone produced in the body and restricts the growth of a cancer cell. Xelucip Tablet can be taken with or without food. Take it exactly and regularly as prescribed by the doctor. Your doctor may change your dose if needed. Do not change your dose or stop taking the medicine without consulting your doctor. Common side effects of this medicine include hot flushes, increased glucose level, musculoskeletal pain, decreased hemoglobin, fatigue, constipation, and diarrhea. If these side effects bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Before taking this medicine, tell your doctor if you have ever had heart disease. Let your doctor also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Let your doctor also know if you have a partner who is pregnant or may become pregnant. Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with this medicine. Benefits of Xelucip Tablet In Treatment of Advanced Prostate cancer Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Xelucip Tablet suppresses the production of testosterone, a hormone that fuels the growth of prostate cancer cells. Reducing testosterone levels helps to shrink tumors and slow the progression of prostate cancer. This also relieves difficulty in passing urine and makes it easier for the patient to urinate. Side effects of Xelucip Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Xelucip Hot flashes Increased glucose level in blood Increased triglyceride level in blood Musculoskeletal (bone, muscle or joint) pain Fatigue Increased aspartate aminotransferase Constipation Diarrhea Increased hemoglobin Increased alanine aminotransferase How to use Xelucip Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xelucip Tablet may be taken with or without food, but it is better to take it at a fixed time. How Xelucip Tablet works Xelucip Tablet works by decreasing the amount of testosterone (a male hormone) produced by the body. This may slow or stop the spread of prostate cancer cells that need testosterone to grow.