Timipar (Timolol Maleate 0.5%) Ophthalmic Solution is a prescription eye drop used to manage elevated intraocular pressure (IOP) in conditions such as open-angle glaucoma and ocular hypertension. By reducing the production of fluid within the eye, it helps lower IOP, thereby reducing the risk of optic nerve damage and potential vision loss. ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common form of glaucoma where the drainage angle in the eye remains open, but the trabecular meshwork is partially blocked, leading to increased IOP. • Ocular Hypertension: A condition characterized by higher-than-normal IOP without any signs of glaucoma damage. ________________________________________ 💊 Dosage and Administration • Typical Dosage: Instill one drop of the 0.5% solution into the affected eye(s) twice daily. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. o After instilling the drop, gently press the corner of your eye (near the nose) for 1–2 minutes to prevent the medication from draining out. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Bronchial asthma or a history of bronchial asthma. o Severe chronic obstructive pulmonary disease (COPD). o Sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock. • Cautions: o Use with caution in patients with a history of heart disease, diabetes, or thyroid disorders, as beta-blockers can mask symptoms of hypoglycemia and hyperthyroidism. o Monitor for potential additive effects when used with other systemic beta-blockers. ________________________________________ 🧪 Mechanism of Action Timolol is a non-selective beta-adrenergic antagonist (beta-blocker) that reduces aqueous humor production in the eye, leading to a decrease in IOP. Its onset of action is typically within 20 minutes, with effects lasting up to 24 hours.

Timipar (Timolol Maleate 0.25%) eye drops are a prescription medication primarily used to manage elevated intraocular pressure (IOP) associated with conditions like open-angle glaucoma and ocular hypertension. By reducing the production of aqueous humor, the fluid inside the eye, Timolol helps lower IOP, thereby reducing the risk of optic nerve damage and potential vision loss . ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common type of glaucoma where the drainage angle in the eye remains open, but the trabecular meshwork is partially blocked, leading to increased IOP. • Ocular Hypertension: A condition characterized by higher-than-normal IOP without any signs of glaucoma damage. ________________________________________ 💊 Dosage and Administration • Typical Dosage: Instill one drop of the 0.25% solution into the affected eye(s) once or twice daily, as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them . ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Bronchial asthma or a history of bronchial asthma. o Severe chronic obstructive pulmonary disease (COPD). • Sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock . • Cautions: o Use with caution in patients with a history of heart disease, diabetes, or thyroid disorders, as beta-blockers can mask symptoms of hypoglycemia and hyperthyroidism. o Monitor for potential additive effects when used with other systemic beta-blockers . ________________________________________ 🧪 Mechanism of Action Timolol is a non-selective beta-adrenergic antagonist (beta-blocker) that reduces aqueous humor production in the eye, leading to a decrease in IOP. Its onset of action is typically within 20 minutes, with effects lasting up to 24 hours .

HYLA FRESH (Sodium Hyaluronate) Eye Drops are designed to provide relief for dry, tired, or irritated eyes. These drops combine sodium hyaluronate with Euphrasia officinalis (Eyebright) extract, offering a soothing effect for various eye discomforts. ________________________________________ 🔍 Uses • Dry Eye Relief: HYLA FRESH helps alleviate dryness caused by environmental factors such as air conditioning, heating, or prolonged screen time. • Contact Lens Comfort: Provides lubrication to reduce discomfort associated with contact lens wear. Environmental Irritation: Soothes eyes irritated by wind, dust, or pollen exposure. Post-Surgical Care: Assists in the healing process following eye surgeries by maintaining moisture and reducing irritation. ________________________________________ 💧 Dosage and Administration • General Dosage: Instill 1–2 drops into the affected eye(s) as needed. • Application Method: 1. Wash your hands thoroughly. 2. Tilt your head back and gently pull down the lower eyelid to create a small pocket. 3. Place the dropper tip near the eye without touching it. 4. Squeeze the bottle to release the prescribed number of drops. 5. Close your eye and blink several times to spread the solution evenly. ________________________________________ ⚠️ Side Effects and Precautions • Common Side Effects: o Temporary blurred vision. o Mild burning or stinging sensation upon application. • Serious Side Effects: o Persistent eye discomfort or redness. o Signs of an allergic reaction (rash, itching, swelling). • Precautions: o Consult a healthcare provider before use if you have any known allergies to the ingredients. o Avoid touching the dropper tip to any surface to prevent contamination. o If you wear contact lenses, remove them before applying the drops unless otherwise directed by your doctor.

SGOS-5 (Sodium Chloride 5% Ophthalmic Solution) is a hypertonic saline eye drop primarily used to treat corneal edema—a condition where the cornea swells due to fluid accumulation, leading to blurred vision and discomfort. ________________________________________ 🔍 Uses • Corneal Edema Management: SGOS-5 helps reduce swelling in the cornea by drawing out excess fluid, thereby improving vision clarity. Post-Surgical Care: It is commonly used after eye surgeries like cataract operations to alleviate corneal swelling. • Treatment of Corneal Disorders: Conditions such as Fuchs' dystrophy or bullous keratopathy, which cause fluid buildup in the cornea, can be managed with SGOS-5. ________________________________________ 💧 Dosage and Administration • Typical Dosage: Instill 1–2 drops into the affected eye(s) every 3 to 4 hours, or as directed by your healthcare provider. • Application Tips: 1. Wash your hands thoroughly before use. 2. Tilt your head back and gently pull down the lower eyelid to form a pocket. 3. Squeeze the prescribed number of drops into the pocket. 4. Close your eye and apply gentle pressure to the inner corner for 1–2 minutes to prevent drainage. 5. Avoid touching the dropper tip to any surface to maintain sterility. ________________________________________ ⚠️ Side Effects and Precautions • Common Side Effects: o Temporary burning or stinging upon application. o Mild irritation or redness. • Temporary blurred vision. • Serious Side Effects: o Persistent eye pain or swelling. o Worsening of vision. • Signs of an allergic reaction (rash, itching, swelling). • Precautions: o Use under medical supervision, especially if you have thyroid disorders. o Not recommended for use in infants under one month of age. o Avoid concurrent use with other antiseptic eye drops containing mercury-based preservatives or sodium thiosulfate.

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

Actorise 25mg Injection – Uses Active Ingredient: Darbepoetin alfa (25 mcg) Main Uses: Anemia in Chronic Kidney Disease (CKD): Actorise 25 is used to treat anemia caused by reduced erythropoietin production in patients with kidney disease. It helps increase red blood cell count, improving oxygen levels and reducing symptoms like fatigue. Anemia from Chemotherapy: In cancer patients undergoing chemotherapy, Actorise helps manage anemia resulting from the suppression of red blood cell production. How It Works: Darbepoetin alfa is a man-made version of erythropoietin, a hormone that encourages the bone marrow to make more red blood cells. This increases hemoglobin levels and improves the body's ability to carry oxygen. Administration: Given by injection under the skin (subcutaneous) or into a vein (intravenous). Should be administered by a healthcare professional. Storage Instructions: Store in a refrigerator at 2°C to 8°C. Do not freeze. Keep away from light. Precautions: Regular blood tests are needed to monitor hemoglobin levels and blood pressure. Not suitable for people with uncontrolled high blood pressure. Avoid if allergic to darbepoetin alfa or any similar medication.

Cynocan 12 Injection is a brand of Cyanocobalamin (Vitamin B₁₂) used to treat and prevent vitamin B₁₂ deficiency. Cyanocobalamin is a synthetic form of vitamin B₁₂, which is essential for nerve function, red blood cell formation, and DNA synthesis. ________________________________________ 🩺 Medical Uses Cynocan 12 Injection is prescribed for: • Pernicious Anemia: A condition where the body cannot absorb vitamin B₁₂ due to a lack of intrinsic factor. • Vitamin B₁₂ Deficiency: Caused by dietary insufficiency, malabsorption, or certain medical conditions. • Neurological Symptoms: Such as numbness, tingling, or weakness in the limbs. • Fatigue and Weakness: Associated with low vitamin B₁₂ levels. • Megaloblastic Anemia: A blood disorder characterized by the presence of abnormally large red blood cells. ________________________________________ ⚙️ Mechanism of Action Cyanocobalamin is converted in the body to its active forms, methylcobalamin and adenosylcobalamin, which are involved in: • DNA Synthesis: Essential for proper cell division. • Red Blood Cell Formation: Prevents anemia. • Nerve Function: Maintains the health of nerve cells. ________________________________________ 💉 Administration and Dosage Cynocan 12 Injection is administered by a healthcare professional: • Intramuscular (IM) or Subcutaneous (SC) Injection: Typically given in a clinical setting. • Dosage: Varies based on the individual's condition and response to treatment. For specific dosing instructions, consult your healthcare provider. ________________________________________ ⚠️ Side Effects Common side effects may include: • Injection site reactions (pain, redness, swelling) • Headache • Nausea or vomiting • Dizziness • Fatigue Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or swelling in the legs. ________________________________________ ⚠️ Precautions Before using Cynocan 12 Injection, inform your healthcare provider if you have: • Allergies to cyanocobalamin or any other components of the injection. • Leber's disease (a hereditary optic nerve disorder). • Kidney or liver disease. • A history of blood clots or stroke. Cyanocobalamin may interact with certain medications. Inform your doctor about all the medicines you are taking, including over-the-counter drugs and supplements.

Methylene Blue Injection is a versatile medication with several clinical uses. It’s a synthetic dye that also functions as a medicinal agent, especially in emergency and critical care settings. ✅ Primary Medical Uses of Methylene Blue Injection Methemoglobinemia Treatment Main use: It rapidly treats methemoglobinemia, a condition where hemoglobin can’t carry oxygen effectively. Converts methemoglobin (Fe³⁺) back to normal hemoglobin (Fe²⁺), restoring oxygen delivery. Urinary Tract Antiseptic (rarely used today) Has mild antiseptic properties in the urinary tract when used with other agents. Ifosfamide-Induced Encephalopathy Used off-label to counteract neurotoxicity caused by the chemotherapy drug ifosfamide. Intraoperative Staining Agent Surgeons and urologists may use it to identify structures (e.g., fistulas, ureters, sentinel lymph nodes). Vasoplegic Syndrome in Cardiac Surgery (off-label) Helps raise blood pressure in cases of refractory hypotension after heart surgery, by inhibiting nitric oxide pathways. Diagnostic Aid Sometimes used to help visualize certain body structures or to test for leaks (like gastrointestinal perforations). ⚠️ Important Warnings & Precautions Serotonin Syndrome Risk: Methylene blue is a monoamine oxidase inhibitor (MAOI) — do not use with SSRIs, SNRIs, or other serotonergic drugs. G6PD Deficiency: Can cause hemolysis in people with glucose-6-phosphate dehydrogenase deficiency. Pregnancy: Generally avoided unless absolutely necessary. 💉 Side Effects Pain at the injection site Nausea, vomiting Headache, dizziness Blue or green discoloration of urine, stool, or skin (temporary and harmless) High doses: confusion, agitation, or chest pain

Sildigra 250 (Sildenafil Citrate) is a high-dose medication primarily used to treat erectile dysfunction (ED) in men. Here’s a quick rundown of its uses, effects, and precautions: ✅ Main Uses of Sildigra 250 Erectile Dysfunction (ED) Helps men achieve and maintain an erection sufficient for sexual activity. Works by increasing blood flow to the penis through the relaxation of smooth muscles and dilation of blood vessels. Pulmonary Arterial Hypertension (off-label use) Sometimes used in lower doses to reduce high blood pressure in the lungs. ⚠️ Important Points to Know High dosage: 250 mg is a very high dose of Sildenafil and is not typically recommended as a starting dose. Standard starting dose is 50–100 mg. Only used in extreme cases and under strict medical supervision. Onset: Starts working in about 30 to 60 minutes. Duration: Effects can last 4–6 hours.