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Eye Care

Tropind Plus is a combination ophthalmic solution containing Tropicamide 0.8% and Phenylephrine 5%. This formulation is primarily used for both diagnostic and therapeutic purposes in ophthalmology. 🩺 Primary Uses of Tropind Plus 1. Pupillary Dilation (Mydriasis): The combination of Tropicamide and Phenylephrine effectively dilates the pupil, allowing eye care professionals to conduct thorough examinations of the retina, optic nerve, and other internal structures. 2. Cycloplegia: Tropicamide paralyzes the ciliary muscle, preventing accommodation (focusing), which is useful in refractive error assessments. 3. Uveitis Management: In cases of uveitis, Tropind Plus helps alleviate pain and prevents further spasms of the eye muscles. 4. Preoperative Preparation: Before surgeries like cataract extraction or retinal procedures, dilating the pupil is essential for clear visualization of the posterior segment. 5. Retinal Imaging: Facilitates procedures such as fundus photography and optical coherence tomography (OCT) by ensuring adequate pupil dilation. ⚙️ How It Works • Tropicamide is a parasympatholytic agent that inhibits the contraction of the circular muscle and paralyzes the ciliary muscle, leading to pupil dilation and cycloplegia. Phenylephrine is a sympathomimetic drug that causes contraction of the radial muscle of the iris, contributing to pupil dilation. Together, these agents produce rapid and effective dilation of the pupil, facilitating detailed eye examinations and procedures. ⚠️ Side Effects Common side effects may include: • Eye pain or stinging • Blurred vision • Sensitivity to light (photophobia) • Allergic reactions These effects are typically temporary and resolve shortly after the examination. 🧪 Safety and Precautions • Driving and Operating Machinery: Avoid activities that require clear vision, such as driving, immediately after application, as the solution can cause temporary blurred vision. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or while breastfeeding, as safety data may be limited. • Drug Interactions: Be cautious when using Tropind Plus with certain medications, especially monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants, as interactions may occur.

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General Medicine

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

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Kidney Disease Medicine

DARCEPT 40MG INJECTION belongs to the class of medication called 'blood-forming agent' primarily used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells' cancer). DARCEPT 40MG INJECTION helps to reverse anaemia and reduce the need for blood transfusion. Anaemia occurs when the body has a lower amount of red blood cells or haemoglobin. In chronic kidney disease, the kidney gets damaged and doesn't filter the blood, leading to anaemia. DARCEPT 40MG INJECTION contains a protein 'Darbepoetin alfa' which works by providing signals to the bone marrow to make more red blood cells. DARCEPT 40MG INJECTION is a biologic response modifier and erythropoiesis-stimulating protein. In chronic kidney disease, when the kidney fails to produce sufficient 'erythropoietin protein' which aids in the formation of red blood cells, DARCEPT 40MG INJECTION stimulates the production of this protein in the bone marrow. DARCEPT 40MG INJECTION will be injected by the healthcare provider. Do not self-administer. The most common side effects of DARCEPT 40MG INJECTION are shortness of breath, cough, low blood pressure during dialysis, headache, body aches, diarrhoea, injection site pain and abdominal pain. Most of these sides effects of DARCEPT 40MG INJECTION do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

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Heart Disorder

Alpostin 500mcg Injection Salt: Alprostadil (500mcg) Description Alpostin 500mcg Injection is used to treat patent ductus arteriosus (PDA), a heart defect that occurs in newborns. It improves blood circulation in such babies and helps treat this defect. Alpostin 500mcg Injection is used to treat patent ductus arteriosus (PDA), a heart defect that occurs in newborns. It improves blood circulation in such babies and helps treat this defect. Alpostin 500mcg Injection is given as an injection by a doctor or nurse and should not be used without medical supervision. The most common side effects of this medicine are interrupted breathing (apnea) and a high temperature for a short time period (transient pyrexia/fever). If your baby has these or any other side effects, let your doctor know. All babies can have Alpostin 500mcg Injection if they need it. The doctor will carry out tests before deciding whether to give this medicine to your baby. However, if your baby develops any signs of allergy to this medicine, such as wheezing, breathlessness, swelling of the face, hands, itchy rash, or redness of the skin, it is advised to not use this medicine. Consult your doctor if you have any doubts. Benefits 1. In Treatment of Patent ductus arteriosus (PDA): Patent ductus arteriosus (PDA) is a persistent opening between the two major blood vessels leading from the heart. Usually this opening closes shortly after birth, but it can remain open and lead to this heart defect in babies. Alpostin 500mcg Injection improves blood flow in such babies who have PDA. It is given as an injection by a doctor or nurse in a hospital setup. Follow your doctor’s instructions carefully to get the most benefit. Side Effects Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Common side effects of Alpostin: - Apnea (absence of breathing) - Fever

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Eye Care

Dorzopar Eye Drops containing Dorzolamide 2% are primarily used to lower intraocular pressure (IOP) in individuals with glaucoma or ocular hypertension (high eye pressure). Here's a detailed breakdown of its uses: 🔹 Primary Uses Open-Angle Glaucoma Dorzolamide is a carbonic anhydrase inhibitor that helps reduce the production of aqueous humor (the fluid inside the eye). By decreasing the amount of fluid produced, it lowers the intraocular pressure (IOP), which is important in treating open-angle glaucoma. Glaucoma is a condition where high eye pressure can damage the optic nerve and lead to vision loss. Ocular Hypertension Dorzopar is also used for the treatment of ocular hypertension, a condition in which the eye pressure is elevated but glaucoma has not yet developed. Lowering eye pressure helps prevent the progression to glaucoma. 🔹 How It Works Dorzolamide works by inhibiting the carbonic anhydrase enzyme in the eye. This enzyme is involved in the production of aqueous humor. By blocking this enzyme, Dorzolamide reduces the amount of fluid produced inside the eye, which in turn lowers the eye pressure. ⚠️ Common Side Effects Eye irritation, burning, or stinging upon application Blurred vision (temporary) Redness in the eyes or foreign body sensation Dry eyes or increased tear production Headaches or dizziness (in some cases) Taste disturbance (a bitter taste in the mouth) 🔹 Usage Tips Dosage: Typically, 1 drop in each affected eye, twice daily (morning and evening), or as prescribed by your healthcare provider. Application Instructions: Wash your hands thoroughly before applying the drops. Tilt your head back slightly and pull down your lower eyelid to form a small pocket. Place one drop in the pocket without touching the dropper tip to your eye. Gently close your eye and blink a few times to help spread the medication. If using other eye medications, wait 5–10 minutes between applications. Contact Lenses: Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them. 🔹 Precautions Kidney or Liver Problems: Since Dorzolamide is metabolized in the body, it should be used with caution in individuals with kidney or liver issues. Pregnancy and Breastfeeding: Consult your doctor before using this medication if you are pregnant or breastfeeding, as the safety of Dorzolamide during pregnancy or while breastfeeding has not been fully established. Eye Infections: Be cautious if you have an eye infection, as Dorzolamide may not be suitable for some active infections. Systemic Effects: While Dorzolamide is generally applied locally to the eye, some systemic absorption may occur, leading to side effects like metabolic acidosis (rare). It should be used cautiously in patients with a history of diabetes, kidney disease, or respiratory problems.

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Kidney Disease Medicine

Zynesp 200 mcg Injection belongs to the class of medication called 'blood-forming agent' primarily used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells' cancer). Zynesp 200 mcg Injection helps to reverse anaemia and reduce the need for blood transfusion. Anaemia occurs when the body has a lower amount of red blood cells or haemoglobin. In chronic kidney disease, the kidney gets damaged and doesn't filter the blood, leading to anaemia. Zynesp 200 mcg Injection contains a protein 'Darbepoetin alfa' which works by providing signals to the bone marrow to make more red blood cells. Zynesp 200 mcg Injection is a biologic response modifier and erythropoiesis-stimulating protein. In chronic kidney disease, when the kidney fails to produce sufficient 'erythropoietin protein' which aids in the formation of red blood cells, Zynesp 200 mcg Injection stimulates the production of this protein in the bone marrow. Zynesp 200 mcg Injection will be injected by the healthcare provider. Do not self-administer. The most common side effects of Zynesp 200 mcg Injection are shortness of breath, cough, low blood pressure during dialysis, headache, body aches, diarrhoea, injection site pain and abdominal pain. Most of these sides effects of Zynesp 200 mcg Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. If you have uncontrolled/untreated high blood pressure or red cell aplasia (a type of anaemia) due to darbepoetin alfa or epoetin alfa, please inform your doctor before taking Zynesp 200 mcg Injection to avoid any complications. Also, mention all the other medications you are taking to affect the way Zynesp 200 mcg Injection works. Inform your doctor immediately, if you feel weak, lightheaded, tired, or short of breath, or if your skin looks pale as it may be signs that the body has stopped responding to Zynesp 200 mcg Injection .

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Kidney Disease Medicine

Oxemia 100 Tablet is a medicine used in the treatment of anemia due to chronic kidney disease. It works by stimulating erythropoietin (a hormone secreted by the kidneys) leading to an increase in the production of red blood cells. It is important that you seek Oxemia 100 Tablet treatment from a doctor who is experienced in providing this medical therapy. It is given under the supervision of a healthcare professional and you should follow all the directions of the doctor strictly. Oxemia 100 Tablet is a medicine that needs to be used with utmost care because it can lead to side effects. It may cause side effects like abdominal pain, vomiting, headache, fever, weakness, and peripheral edema. If you notice these side effects or do not resolve, please inform the doctor. If you notice severe side effects, please inform the doctor. The doctor may suggest ways to treat or prevent any such side effects from occurring again.

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Kidney Disease Medicine

Oxemia 50 Tablet is a medicine used in the treatment of anemia due to chronic kidney disease. It works by stimulating erythropoietin (a hormone secreted by the kidneys) leading to an increase in the production of red blood cells. It is important that you seek Oxemia 50 Tablet treatment from a doctor who is experienced in providing this medical therapy. It is given under the supervision of a healthcare professional and you should follow all the directions of the doctor strictly. Oxemia 50 Tablet is a medicine that needs to be used with utmost care because it can lead to side effects. It may cause side effects like abdominal pain, vomiting, headache, fever, weakness, and peripheral edema. If you notice these side effects or do not resolve, please inform the doctor. If you notice severe side effects, please inform the doctor. The doctor may suggest ways to treat or prevent any such side effects from occurring again.

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General Medicine

Dopacan Injection is a brand of Dopamine Hydrochloride, a potent vasopressor and inotropic agent used in critical care settings to manage various cardiovascular conditions. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dopacan Injection is indicated for: • Shock Management: Including septic shock, cardiogenic shock, and hypovolemic shock. • Acute Heart Failure: To improve cardiac output and perfusion. • Severe Hypotension: Especially in patients unresponsive to volume resuscitation. • Renal Protection: To enhance renal blood flow and urine output in certain critically ill patients. Dopamine works by stimulating dopaminergic and beta-adrenergic receptors, leading to increased heart rate, contractility, and renal perfusion. At higher doses, it also stimulates alpha-adrenergic receptors, causing vasoconstriction and increased blood pressure. ________________________________________ ⚙️ Dosage and Administration Dopacan Injection is administered intravenously, with the dosage tailored to the patient's condition and response: • Low Dose (1–5 mcg/kg/min): Primarily stimulates dopaminergic receptors, increasing renal blood flow and urine output. • Medium Dose (5–15 mcg/kg/min): Stimulates beta-1 adrenergic receptors, enhancing heart rate and contractility. • High Dose (15–50 mcg/kg/min): Stimulates alpha-1 adrenergic receptors, leading to vasoconstriction and increased blood pressure. Continuous monitoring of blood pressure, heart rate, and urine output is essential during administration. ________________________________________ ⚠️ Precautions and Contraindications Before using Dopacan Injection, inform your healthcare provider if you have: • Allergies to dopamine or other components of the injection. • A history of heart rhythm disorders or coronary artery disease. • Pheochromocytoma (a rare tumor of the adrenal glands). • Diabetes, asthma, or sulfite allergies. • Circulatory disorders such as Raynaud's disease or Buerger's disease. • Recent use of monoamine oxidase inhibitors (MAOIs). This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. ________________________________________ 💊 Side Effects Common side effects may include: • Palpitations or increased heart rate. • Nausea and vomiting. • Headache. • Difficulty breathing. • Gangrene (in rare cases, due to excessive vasoconstriction). Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.

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