About the brand Malegra 50 is marketed globally by Sunrise. About the drug Malegra 50 Mg An active ingredient in Malegra 50 is Sildenafil citrate. Sildenafil citrate is used in the treatment for erectile dysfunction treatment (inadequate penile erection during sexual activity), pulmonary hypertension (high pressure in blood vessels of lungs), benign prostatic hyperplasia (enlarged prostate). Manufacturer of Malegra 50 Mg Malegra 50 having 50 mg of sildenafil citrate is manufactured by sunrise. It is mainly marketed and supplied by the company and its associates in India. Strength Malegra 50 having 50 mg of Sildenafil citrate. USA Brands Equivalent to Sildenafil citrate the salt in Malegra 50 Mg Viagra is the USA brand equivalent to Malegra 50 Use of Sildenafil citrate the salt in Malegra 50 Mg It is used to treat erectile dysfunction (ED). In men, it is used to treat the signs of an enlarged prostate. It is used to treat raised pressure in the lungs. It may be given to you for other reasons. Talk with the doctor. Erectile dysfunction: It is a medical condition, in which, proper erection of penis is a problem. Men are not able to erect their penis even during sexual stimulation. This leads to impotency. Malegra 50 helps in relaxing the veins and arteries in penis leading to perfect erection before sexual activity and thus increase the satisfaction level during sexual intercourse Pulmonary Arterial Hypertension: It is a condition in which there is a raised pressure in your lungs. Malegra 50 relax blood vessels in the lungs leads to lowering of blood pressure. Benign prostatic hyperplasia: it is a condition in which your prostate gland is enlarged. Malegra 50 improve the blood flow to the prostate and relax the muscles in the prostate and bladder and thus help in relieving urinary symptoms. Usually, a high dose is used for Pulmonary Arterial Hypertension than the other two indications. How Malegra 50 Mg works Malegra 50 having Sildenafil citrate works by inhibiting the phosphodiesterase type 5 in the body. Thus it stops the degradation of cGMP( Cyclic guanosine monophosphate). Availability of cGMP helps relax the veins in penis and thus helps in erection when there is a need for sexual activity or sexual stimulation. Inhibition of phosphodiesterase type 5 (PDE-5) in smooth muscle of pulmonary blood vessels results in its relaxation of and it helps to reduce the pressure in your lungs. How to take Malegra 50 Mg Malegra 50 having salt Sildenafil citrate shall be taken before 1 hour of sexual intercourse with a glass of water. More information will be directed by your doctor. Hence consult your doctor before having Malegra 50. Sildenafil Dosage Sildenafil citrate the active salt in Malegra 50 is to be taken usually in a dosage which ranges from 25 mg to 100 mg. More specific dose will be directed by your doctor. Hence, do not take Malegra 50 without consulting with your doctor. How long should Malegra 50 Mg be continued Malegra 50 having sildenafil citrate is a need to basis medicine. Consult your doctor regarding the intake and stoppage of the drug. Do not take a decision on your own. Consult your doctor for each possible steps. Dose of Malegra 50 Mg missed The possible chances of missing the dose of the drug is minimal, however, consult your doctor regarding the same. The drug is mainly taken before the actual sexual intercourse, hence missing the dose is rare. Drug interaction with Sildenafil citrate the salt in Malegra 50 Mg Nitrates(Isosorbide dinitrate, isosorbide mononitrate, nitroglycerin) generally react with Sildenafil citrate, the salt present in Malegra 50. Tell your doctor If you are taking any of these drugs: Itraconazole or ketoconazole, riociguat, or ritonavir, rifampin. If you are taking another brand that has the same active ingredient (sildenafil citrate) If you are taking another drug in the same class as of sildenafil citrate (eg: tadalafil) If you are taking any of these drugs-alfuzosin, doxazosin, silodosin, tamsulosin, terazosin When not to take Malegra 50 Mg Do not take Malegra 50 if you have allergic reactions with the salt or excipients. Sildenafil Adverse Effects / Side effects Some patients may have allergic reactions. Inform your doctor if you have any signs of allergic reaction like rash, itching, red-swollen skin, fever, trouble breathing, swollen face etc. Chest pain or pressure A fast heartbeat or a heartbeat that does not feel normal. Dizziness or passing out. Severe headache. Weakness on one side of the body, trouble speaking or thinking, loss of balance, drooping on one side of the face, or blurred eyesight. Change in eyesight. Loss of eyesight. Hearing loss or change in hearing Ringing in ears. Very bad muscle pain, back pain, soreness, or weakness. If you have a painful erection (hard penis) or an erection that lasts for longer than 4 hours, then call your doctor immediately. It should be treated properly otherwise it may cause lasting sex problems. Overdose E

Paripher Eye Drop contains Phenylephrine Hydrochloride 10% and is primarily used in ophthalmology for its mydriatic (pupil-dilating) effects. This formulation is typically employed in clinical settings and is available by prescription.** ________________________________________ 🔍 Uses 1. Pupil Dilation (Mydriasis): Paripher is utilized to dilate the pupil during eye examinations and surgical procedures, allowing for a clearer view of the retina and other internal structures. 2. Treatment of Eye Redness and Irritation: As a decongestant, it constricts blood vessels in the eye, reducing redness and irritation caused by allergies or other factors. 3. Management of Uveitis: Phenylephrine's vasoconstrictive properties aid in managing inflammation associated with uveitis by decreasing blood flow to the affected area. 4. Adjunct in Nasal Decongestion: Though primarily an eye drop, Paripher's active ingredient is also utilized in nasal decongestants to relieve symptoms of the common cold. ________________________________________ ⚠️ Usage Instructions • Application: Instill the prescribed number of drops into the lower conjunctival sac of the eye. • Contact Lenses: Remove soft contact lenses before application and wait at least 10–15 minutes before reinsertion. • Avoid Contamination: Do not touch the dropper tip to any surface, including the eye, to prevent contamination. • Multiple Medications: If using other eye medications, wait at least 10 minutes before applying them to avoid dilution. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects: Temporary eye discomfort, such as stinging or burning sensations. • Serious Side Effects: Although rare, systemic absorption may lead to increased blood pressure, headache, or dizziness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.

Paripher Eye Drop is a pharmaceutical product containing Phenylephrine Hydrochloride 5%. It is primarily used in ophthalmology for various diagnostic and therapeutic purposes. ________________________________________ 🔍 Uses of Paripher Eye Drop 1. Pupil Dilation (Mydriasis): Paripher is commonly employed to dilate the pupil during eye examinations and surgical procedures, facilitating a clearer view of the retina and other internal structures. 2. Treatment of Eye Redness and Irritation: As a decongestant, it constricts blood vessels in the eye, reducing redness and irritation caused by allergies or other factors. 3. Management of Uveitis: Phenylephrine's vasoconstrictive properties aid in managing inflammation associated with uveitis by decreasing blood flow to the affected area. 4. Adjunct in Nasal Decongestion: Though primarily an eye drop, Paripher's active ingredient is also utilized in nasal decongestants to relieve symptoms of the common cold. ________________________________________ ⚠️ Usage Instructions • Application: Instill the prescribed number of drops into the lower conjunctival sac of the eye. • Contact Lenses: Remove soft contact lenses before application and wait at least 10–15 minutes before reinsertion. • Avoid Contamination: Do not touch the dropper tip to any surface, including the eye, to prevent contamination. • Multiple Medications: If using other eye medications, wait at least 10 minutes before applying them to avoid dilution. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects: Temporary eye discomfort, such as stinging or burning sensations. • Serious Side Effects: Although rare, systemic absorption may lead to increased blood pressure, headache, or dizziness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.

7 PM Eye Drop is a medicine used to reduce pressure in the eyes in people with glaucoma and ocular hypertension (high pressure in the eye). If the pressure in your eye is too high it can damage your sight, potentially leading to blindness. It works by helping fluid flow from inside the eye into the blood. 7 PM Eye Drop is suitable for adults and children and can be used by itself or in combination with other eye medicines to reduce pressure. Follow the instructions given by your doctor and use this medicine regularly to get the most benefit. If you stop using it, pressure in the eye could increase and damage your sight. Never use a bottle if the seal is broken before you use it for the first time. If you wear contact lenses, make sure you remove them before instilling and wait for at least 15 minutes before putting them back. The most common side effects include eyelashes changes, eye pain and sensitivity to light. It may also cause blurred vision, dryness in the eye, a gradual change in color of the eye, and other rare effects. If you get any side effects, talk to your doctor. Your doctor may be able to tell you ways of reducing or preventing some side effects or suggest another treatment. If your vision is blurred or you have other changes in sight for a time, do not drive until your vision is clear. This is usually a short-term side effect. Do not use this medicine if you are pregnant or trying to become pregnant, or if you are breastfeeding.

7.30 PM Eye Drop is a medicine used to reduce pressure in the eyes in people with glaucoma and ocular hypertension (high pressure in the eye). If the pressure in your eye is too high it can damage your sight, potentially leading to blindness. It works by helping fluid flow from inside the eye into the blood. 7.30 PM Eye Drop is suitable for adults and children and can be used by itself or in combination with other eye medicines to reduce pressure. Follow the instructions given by your doctor and use this medicine regularly to get the most benefit. If you stop using it, pressure in the eye could increase and damage your sight. Never use a bottle if the seal is broken before you use it for the first time. If you wear contact lenses, make sure you remove them before instilling and wait for at least 15 minutes before putting them back. The most common side effects include eyelashes changes, eye pain and sensitivity to light. It may also cause blurred vision, dryness in the eye, a gradual change in color of the eye, and other rare effects. If you get any side effects, talk to your doctor. Your doctor may be able to tell you ways of reducing or preventing some side effects or suggest another treatment. If your vision is blurred or you have other changes in sight for a time, do not drive until your vision is clear. This is usually a short-term side effect. Do not use this medicine if you are pregnant or trying to become pregnant, or if you are breastfeeding.

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

Nitrocan 25 Injection is a brand of Nitroglycerin Injection 25 mg/5 mL, manufactured by American Remedies. It is primarily used in hospital settings for the management of certain cardiovascular conditions. ________________________________________ ✅ Primary Uses Nitrocan 25 Injection is indicated for: • Angina Pectoris: To treat and prevent chest pain caused by reduced blood flow to the heart. • Acute Myocardial Infarction (Heart Attack): To alleviate chest pain and improve blood flow to the heart muscle. Hypertension During Surgery: To control high blood pressure during and after surgical procedures. • Congestive Heart Failure: To reduce the workload on the heart and improve symptoms. ________________________________________ ⚙️ Mechanism of Action Nitroglycerin is a nitrate that, once administered, is converted into nitric oxide in the body. This leads to the relaxation and dilation of blood vessels, improving blood flow and reducing the heart's workload. ________________________________________ ⚠️ Precautions • Contraindications: Should not be used in patients with severe anemia, hypotension, or those taking medications for erectile dysfunction (e.g., sildenafil, tadalafil) due to the risk of a significant drop in blood pressure. • Monitoring: Requires careful monitoring of blood pressure and heart rate during administration. • Administration: Administered intravenously under medical supervision; dosage and duration are determined by the healthcare provider. ________________________________________ 💊 Common Side Effects • Headache • Dizziness or lightheadedness • Hypotension (low blood pressure) • Nausea or vomiting • Flushing

Milrican 10 is a brand of Milrinone Lactate Injection, manufactured by American Remedies. Milrinone is a phosphodiesterase-3 (PDE3) inhibitor that serves as both an inotropic agent and a vasodilator. ________________________________________ ✅ Primary Uses of Milrican 10 Milrican 10 is indicated for the short-term intravenous treatment of: • Severe congestive heart failure: Particularly in patients unresponsive to conventional therapies. • Acute decompensated heart failure: Including low output states following cardiac surgery. It is commonly used in intensive care units or during cardiac procedures to support heart function. ________________________________________ ⚙️ Mechanism of Action Milrinone works by inhibiting PDE3, leading to increased cyclic AMP (cAMP) levels in cardiac and vascular smooth muscle cells. This results in: • Increased myocardial contractility: Enhancing the heart's ability to pump blood. • Vasodilation: Relaxing blood vessels, which reduces the heart's workload and improves blood flow. ________________________________________ ⚠️ Important Considerations • Administration: Milrican 10 should only be administered intravenously under the supervision of a healthcare professional. • Monitoring: Patients receiving Milrican 10 require close monitoring of blood pressure, heart rate, and kidney function. • Contraindications: Not recommended for patients with severe dehydration, electrolyte imbalances, or known hypersensitivity to milrinone. • Pregnancy and Breastfeeding: Consult a doctor before use if pregnant or breastfeeding.

Aggramed 5mg Infusion is a blood thinner which prevents formation of harmful blood clots. It helps to prevent a heart attack in patients presenting with severe chest pain due to a sudden decrease in blood flow to the heart. Aggramed 5mg Infusion is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. You should continue all your other medicines that are advised by the doctor for your long term treatment even after this injection. Common side effects of this medicine include headaches, hematoma, nausea, ecchymosis, postoperative bleeding, and blood in stool or urine. Let your doctor know immediately if you see pinpoint rash or blood in your vomits, urine, or stool.