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'important disodium edta'

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General Medicine

Disodium Edetate Injection (also written as EDTA Disodium or Disodium EDTA) is a chelating agent with very limited and specific medical uses due to the risk of serious side effects. 🔹 Approved Medical Uses of Disodium Edetate Injection: 🔻 Treatment of Severe Hypercalcemia Primary use: Treats life-threatening high calcium levels in the blood. It binds to excess calcium ions and helps remove them from the body via the kidneys. 💊 Digitalis (Digoxin) Toxicity (rare/adjunct) In cases of digoxin overdose, disodium EDTA may be used to lower calcium, which worsens digoxin's toxic effects. ⚠️ NOT for Lead Poisoning ⚠️ Very important: Disodium EDTA is not used for lead poisoning. It can dangerously lower blood calcium and cause fatal hypocalcemia. The safe version for lead chelation is Calcium Disodium EDTA (CaNa₂EDTA). 💉 How It’s Given: Intravenously (IV) and must be administered slowly. Requires monitoring of calcium and kidney function. ⚠️ Risks and Side Effects: Severe hypocalcemia (can cause seizures, cardiac arrhythmias, or death). Kidney damage Nausea, vomiting, headache Blood pressure drops Injection site irritation 🚫 Not Approved For: “Detox” or anti-aging therapy Cardiovascular or atherosclerosis treatment (not FDA-approved and unsafe) ✅ Summary: Condition Use of Disodium EDTA Severe Hypercalcemia ✅ Yes Digoxin (digitalis) toxicity ⚠️ Rare, supportive Lead or heavy metal poisoning ❌ NO (use CaNa₂EDTA) Detox / cosmetic use ❌ Not approved/safe

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General Medicine

Disodium EDTA Injection (Ethylenediaminetetraacetic acid, disodium salt) is a chelating agent, similar to calcium disodium EDTA, but with different uses, safety profile, and risks. It’s much less commonly used today due to safety concerns and has narrower indications. 🔹 Main Uses of Disodium EDTA Injection: 🦙 Hypercalcemia (High Blood Calcium Levels) It can be used in emergency treatment of severe hypercalcemia, especially when rapid calcium reduction is required. It works by binding free calcium ions in the blood. 🫀 Digitalis Toxicity (rare use) Sometimes used to manage digoxin toxicity by lowering calcium levels, as excess calcium can worsen digoxin effects. 🧪 Experimental or Unapproved Use: Chelation therapy for atherosclerosis (plaque buildup in arteries): Previously promoted in 'alternative' medicine as a treatment for heart disease. ⚠️ Not FDA-approved for cardiovascular use due to risk of severe side effects including death. ⚠️ Important Warnings & Safety Concerns: Disodium EDTA has been associated with fatal hypocalcemia (low calcium levels) when misused. Because of this, it is generally not used for lead poisoning—Calcium Disodium EDTA (CaNa₂EDTA) is the preferred and safer agent. It requires hospital setting administration with continuous monitoring. 💉 How It’s Given: Administered via IV infusion. Given slowly to prevent rapid electrolyte shifts and heart complications. 🚫 Not Used For: Lead poisoning — too dangerous due to calcium depletion. General detox — not approved or supported by scientific evidence.

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General Medicine

Calcium Edetate Injection (also known as Calcium Disodium EDTA) is a chelating agent used mainly to treat heavy metal poisoning, particularly lead poisoning. 🔹 Primary Uses of Calcium Edetate Injection: 🧪 Lead Poisoning (Plumbism) Main use: binds to lead in the bloodstream and helps eliminate it through the urine. Often used in moderate to severe cases, especially in children and industrial exposure. 🌡️ Other Heavy Metal Toxicity (off-label or less common) May also be used (less commonly) for: Cadmium Zinc (in overload situations) Not used for mercury or arsenic—other chelators like dimercaprol or DMSA are preferred there. 🔄 Diagnostic Use (EDTA lead mobilization test) Sometimes used to test the body's lead burden by observing how much lead is excreted after administration. 💉 How It Works: Chelation therapy: The EDTA binds to heavy metal ions in the blood. The resulting complex is water-soluble and excreted through the kidneys. 💉 Administration: IV (intravenous) or IM (intramuscular) injection. Usually given over several days, depending on lead levels and patient condition. Often used alongside hydration therapy to protect the kidneys. ⚠️ Precautions & Side Effects: Kidney function must be closely monitored — chelation can be hard on the kidneys. Electrolyte imbalances (e.g., calcium, zinc depletion) may occur. Possible side effects: Fever, chills Nausea, vomiting Injection site pain Low blood pressure (rare but serious) ❗ Important Notes: Not the same as disodium EDTA, which is more toxic and not approved for lead poisoning. Must be used under strict medical supervision, especially in children.

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Cats and Dogs

Aromacalm® is dedicated to dogs and cats prone to stress and stress-associated skin disorders. This collar helps calm your pets while soothing and hydrating their skin. Changes of environment (moving, adoption, cohabitation, separation…) Occasional situations (traveling, veterinay consultation, excessive noise…) The patented technology of Aromacalm® enables a continuous and constant diffusion of the ingredients during 1 month. A specific safety quick-release system specifically designed for cats will allow the Aromacalm® collar to enlarge and break in case of important tension.

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General Medicine

Milrican 10 is a brand of Milrinone Lactate Injection, manufactured by American Remedies. Milrinone is a phosphodiesterase-3 (PDE3) inhibitor that serves as both an inotropic agent and a vasodilator. ________________________________________ ✅ Primary Uses of Milrican 10 Milrican 10 is indicated for the short-term intravenous treatment of: • Severe congestive heart failure: Particularly in patients unresponsive to conventional therapies. • Acute decompensated heart failure: Including low output states following cardiac surgery. It is commonly used in intensive care units or during cardiac procedures to support heart function. ________________________________________ ⚙️ Mechanism of Action Milrinone works by inhibiting PDE3, leading to increased cyclic AMP (cAMP) levels in cardiac and vascular smooth muscle cells. This results in: • Increased myocardial contractility: Enhancing the heart's ability to pump blood. • Vasodilation: Relaxing blood vessels, which reduces the heart's workload and improves blood flow. ________________________________________ ⚠️ Important Considerations • Administration: Milrican 10 should only be administered intravenously under the supervision of a healthcare professional. • Monitoring: Patients receiving Milrican 10 require close monitoring of blood pressure, heart rate, and kidney function. • Contraindications: Not recommended for patients with severe dehydration, electrolyte imbalances, or known hypersensitivity to milrinone. • Pregnancy and Breastfeeding: Consult a doctor before use if pregnant or breastfeeding.

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General Medicine

Menacan K3 Injection is a brand name for Menadione Sodium Bisulphite Injection, which is a synthetic form of Vitamin K3. It is primarily used in medical and veterinary settings to address Vitamin K deficiencies and related conditions. ________________________________________ 💉 Medical Uses Menacan K3 Injection is indicated for: • Treatment of Vitamin K Deficiency: Essential for synthesizing clotting factors II, VII, IX, and X in the liver. A deficiency can lead to bleeding disorders. • Management of Hypoprothrombinemia: A condition characterized by low levels of prothrombin, increasing the risk of bleeding • Reversal of Anticoagulant Effects: Used in cases of anticoagulant overdose, particularly when rapid reversal is necessary. • Support in Liver Disease: Beneficial for patients with liver disease where vitamin K absorption is impaired. • Treatment of Malabsorption Syndromes: In patients with conditions that disrupt vitamin K absorption. ________________________________________ ⚠️ Important Considerations • Administration: Should only be administered by a trained healthcare professional. Self-administration is not recommended. • Contraindications: Not suitable for individuals with G6PD deficiency, as it can cause serious side effects. Also, use with caution in patients with liver or kidney disease, or those who are pregnant or breastfeeding. • Side Effects: May include facial flushing, sweating, injection site reactions, hemolysis, and altered taste. These side effects are generally mild and resolve over time.

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