Pirfenex Tablet is a prescription medicine used in the treatment of idiopathic pulmonary fibrosis. It reduces scarring and swelling in the lungs and helps to breathe better. Pirfenex Tablet is best taken with food. Take it at the same time every day to get the most benefits. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. The most common side effects of this medicine include insomnia, headache, dizziness, dyspepsia, nausea, diarrhea, and photosensitivity. To overcome dizziness, avoid driving or attention-seeking activity. Some people may experience weight loss and other side effects. Monitor your weight regularly or ask for the doctor's advice in such cases. Your doctor also may perform a liver function test while on treatment with this medicine.

INTRODUCTION ABALAM 600/300 is a combination of Abacavir and Lamivudine which belongs to the group of medicines called Anti-viral agents. It is used in the management of HIV infection in adults, adolescents and in children (weighing above 25 kgs). HIV (human immunodeficiency virus) infection is a viral infection that damages our immune system and weakens our body’s ability to fight against various infections. Both abacavir and lamivudine are nucleoside reverse transcriptase inhibitors. They work by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. This prevents further multiplication of viral cells within the body. Also, they can improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. ABALAM 600/300 cannot not manage HIV infection completely. It can reduce only the number of viral cells present in the body and maintains them at a lower level. During management with ABALAM 600/300 your doctor will closely monitor your body weight, blood cholesterol levels and blood sugar levels to reduce the risk of unwanted side effects. Do not take ABALAM 600/300 if you are allergic to abacavir or lamivudine. Before taking ABALAM 600/300 inform your doctor if you have diabetes or any liver (hepatitis C or B infection), kidney or heart problems. If you are already taking ABALAM 600/300 to manage hepatitis B or C infection, do not stop taking it without consulting your doctor. Even if you take ABALAM 600/300, it is important for you to follow certain measures to prevent the spread of infections to the other people (such as avoid having unprotected sexual intercourse or sharing needles or personal items like toothbrush, razors etc with other people). ABALAM 600/300 is not recommended for use in pregnant or breastfeeding women. The most common side effects of taking ABALAM 600/300 are difficulty in sleeping, increased signs of infections, nausea, stomach pain, headache, or dizziness. Consult your doctor if any of these side effects worsens. Also inform your doctor immediately if you experience severe fever with extreme tiredness, sudden changes in body weight or severe stomach pain along with dark urine after taking ABALAM 600/300. USES OF ABALAM 600/300 Manages HIV infection in adults, adolescents and in children (weighing above 25 kgs) HOW ABALAM 600/300 WORKS ABALAM 600/300 is an anti-retroviral medicine. It controls the multiplication of viral cell within the body, by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. It can also improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. DIRECTIONS FOR USE Take ABALAM 600/300 as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. ABALAM 600/300 can be taken with or without meals. Your doctor will decide the correct dose and for how long ABALAM 600/300 must be taken depending upon your age, body weight and severity of the infection. Do not stop taking ABALAM 600/300 without consulting your doctor as it may reduce its effectiveness. SIDE EFFECTS OF ABALAM 600/300 COMMON difficulty in sleeping feeling depressed headache, tiredness, dizziness nausea, diarrhoea fever, skin rash stomach pain loss of appetite irritated or runny nose hair loss UNCOMMON decrease in RBC, WBC, and platelets RARE Stop taking ABALAM 600/300 and contact your doctor immediately if you experience any of the following side effects: signs of allergic reactions (such as skin rash, fever, accompanied with sore throat, cough, nausea, vomiting, stomach pain, diarrhea, tiredness, joint pain, muscle pain, swelling of the neck, difficulty in breathing, mouth ulcers, occasional headaches, inflammation of the eye, low blood pressure, sense of tingling or numbness of hands or feet) pure red cell aplasia (failure of bone marrow to produce new red blood cells) signs of infections (such as fever, headache, stomach-ache, breathing difficulty) signs of auto-immune disorders (such as rapid or irregular heartbeat, tremor, hyperactivity, general weakness) signs of osteonecrosis (death of bone cells causing joint stiffness, pain in the hip, knee or shoulder and difficulty in moving) signs of liver problems (such as yellowing of the skin and whites of the eye, dark urine, light-coloured stools, loss of appetite, nausea, pain, tenderness on the right side of stomach) heart attack changes in body fat (such as increase fat in the shoulder and neck (buffalo hump), breast, and in the middle body or fat loss from the legs, arms, or face)

Marketer Emcure Pharmaceuticals Ltd SALT COMPOSITION Emtricitabine (200mg) + Tenofovir disoproxil fumarate (300mg) Storage Store below 30°C Uses of Tavin EM Tablet Treatment of HIV infection Product introduction Tavin EM Tablet belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It helps control HIV infection so your immune system can work better. Tavin EM Tablet is not a cure for HIV/AIDS and only helps to decrease the amount of HIV in your body. This helps lower your risk of getting HIV-related complications and improves your lifespan. It may also be used to prevent HIV infection in some people at high risk. It may be prescribed alone or in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need. Carefully follow the instructions for all the medicines that you are given. Taking these medicines regularly at the right time greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop. Common side effects of this medicine include nausea, diarrhea, headache, trouble sleeping, rash, and dizziness. These are usually not serious, but inform your doctor if they bother you or do not go away. It can also increase the risk of bone loss (osteoporosis) if you take it for a long time. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor. Some people put on weight while taking medicines to treat HIV/AIDS. Before taking it, let your doctor know if you have any liver or kidney disease or bone problems. While using it, you may need regular blood tests to check your blood counts, liver function, and kidney function. Since this medicine may cause dizziness or sleepiness, do not drive if you experience these symptoms. Pregnant or breastfeeding women should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes if you are HIV positive. Talk to your doctor about safe ways, like condoms, to prevent HIV transmission during sex. Benefits of Tavin EM Tablet In Treatment of HIV infection Tavin EM Tablet prevents the HIV from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life. It is not a cure for HIV or AIDS, and should not be used to prevent HIV after accidental exposure to a risk. Take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines. However, taking this medicine will not prevent you from passing HIV to other people. Side effects of Tavin EM Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Tavin EM Nausea Diarrhea Headache Depression Rash Dizziness Fatigue Vomiting Insomnia (difficulty in sleeping) Weakness Abnormal dreams Abdominal pain Weight loss How to use Tavin EM Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tavin EM Tablet may be taken with or without food, but it is better to take it at a fixed time. How Tavin EM Tablet works Tavin EM Tablet is a combination of two anti-HIV medicines: Emtricitabine and Tenofovir disoproxil fumarate. They prevent HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

Marketer Hetero Drugs Ltd SALT COMPOSITION Emtricitabine (200mg) + Tenofovir disoproxil fumarate (300mg) Storage Store below 30°C Uses of Tenof EM Tablet Treatment of HIV infection Product introduction Tenof EM Tablet belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It helps control HIV infection so your immune system can work better. Tenof EM Tablet is not a cure for HIV/AIDS and only helps to decrease the amount of HIV in your body. This helps lower your risk of getting HIV-related complications and improves your lifespan. It may also be used to prevent HIV infection in some people at high risk. It may be prescribed alone or in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need. Carefully follow the instructions for all the medicines that you are given. Taking these medicines regularly at the right time greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop. Common side effects of this medicine include nausea, diarrhea, headache, trouble sleeping, rash, and dizziness. These are usually not serious, but inform your doctor if they bother you or do not go away. It can also increase the risk of bone loss (osteoporosis) if you take it for a long time. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor. Some people put on weight while taking medicines to treat HIV/AIDS. Before taking it, let your doctor know if you have any liver or kidney disease or bone problems. While using it, you may need regular blood tests to check your blood counts, liver function, and kidney function. Since this medicine may cause dizziness or sleepiness, do not drive if you experience these symptoms. Pregnant or breastfeeding women should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes if you are HIV positive. Talk to your doctor about safe ways, like condoms, to prevent HIV transmission during sex. Benefits of Tenof EM Tablet In Treatment of HIV infection Tenof EM Tablet prevents the HIV from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life. It is not a cure for HIV or AIDS, and should not be used to prevent HIV after accidental exposure to a risk. Take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines. However, taking this medicine will not prevent you from passing HIV to other people. Side effects of Tenof EM Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Tenof EM Nausea Diarrhea Headache Depression Rash Dizziness Fatigue Vomiting Insomnia (difficulty in sleeping) Weakness Abnormal dreams Abdominal pain Weight loss How to use Tenof EM Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tenof EM Tablet may be taken with or without food, but it is better to take it at a fixed time. How Tenof EM Tablet works Tenof EM Tablet is a combination of two anti-HIV medicines: Emtricitabine and Tenofovir disoproxil fumarate. They prevent HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Tenof EM Tablet. Please consult your doctor. warnings Pregnancy SAFE IF PRESCRIBED Tenof EM Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Marketer Cipla Ltd SALT COMPOSITION Emtricitabine (200mg) + Tenofovir disoproxil fumarate (300mg) Storage Store below 30°C Uses of Tenvir-EM Tablet Treatment of HIV infection Product introduction Tenvir-EM Tablet belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It helps control HIV infection so your immune system can work better. Tenvir-EM Tablet is not a cure for HIV/AIDS and only helps to decrease the amount of HIV in your body. This helps lower your risk of getting HIV-related complications and improves your lifespan. It may also be used to prevent HIV infection in some people at high risk. It may be prescribed alone or in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need. Carefully follow the instructions for all the medicines that you are given. Taking these medicines regularly at the right time greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop. Common side effects of this medicine include nausea, diarrhea, headache, trouble sleeping, rash, and dizziness. These are usually not serious, but inform your doctor if they bother you or do not go away. It can also increase the risk of bone loss (osteoporosis) if you take it for a long time. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor. Some people put on weight while taking medicines to treat HIV/AIDS. Before taking it, let your doctor know if you have any liver or kidney disease or bone problems. While using it, you may need regular blood tests to check your blood counts, liver function, and kidney function. Since this medicine may cause dizziness or sleepiness, do not drive if you experience these symptoms. Pregnant or breastfeeding women should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes if you are HIV positive. Talk to your doctor about safe ways, like condoms, to prevent HIV transmission during sex. Benefits of Tenvir-EM Tablet In Treatment of HIV infection Tenvir-EM Tablet prevents the HIV from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life. It is not a cure for HIV or AIDS, and should not be used to prevent HIV after accidental exposure to a risk. Take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines. However, taking this medicine will not prevent you from passing HIV to other people. Side effects of Tenvir-EM Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Tenvir-EM Nausea Diarrhea Headache Depression Rash Dizziness Fatigue Vomiting Insomnia (difficulty in sleeping) Weakness Abnormal dreams Abdominal pain Weight loss How to use Tenvir-EM Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tenvir-EM Tablet may be taken with or without food, but it is better to take it at a fixed time. How Tenvir-EM Tablet works Tenvir-EM Tablet is a combination of two anti-HIV medicines: Emtricitabine and Tenofovir disoproxil fumarate. They prevent HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

INTRODUCTION ABOUT VALCYTE 450MG TABLET VALCYTE 450MG TABLET contains Valganciclovir which belongs to the group of medicines called Antiviral agents. It is used in adults (with acquired immunodeficiency syndrome) to manage cytomegalovirus (CMV) infection of the retina of the eye which generally cause vision problems and blindness. VALCYTE 450MG TABLET is also used in adults and children to manage cytomegalovirus (CMV) infection who are not infected with CMV or who had received an organ transplant from someone who earlier had CMV infection. VALCYTE 450MG TABLET is not recommended for use in patients allergic (hypersensitive) to Valganciclovir, and/or Ganciclovir. Before taking VALCYTE 450MG TABLET, inform your doctor if are undergoing radiotherapy/hemodialysis, and/or suffer from low red blood cell, white blood cell or platelets, kidney/liver problems. VALCYTE 450MG TABLET is not recommended for use in pregnant women unless it is clearly necessary since it may cause harm to the unborn baby. It is also not recommended for use in breastfeeding women. VALCYTE 450MG TABLET should be used with caution in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 65 years and above) after consulting the doctor. The most common side effects of taking VALCYTE 450MG TABLET are oral thrush (fungal infection), headache, shortness of breath, abdominal pain, loss of appetite, nausea, vomiting, and/or diarrhea. Consult your doctor if any of these symptoms worsens. USES OF VALCYTE 450MG TABLET Manage cytomegalovirus (CMV) infection of the retina of the eye in adult patients with acquired immunodeficiency syndrome (AIDS). Prevents cytomegalovirus (CMV) infection who are not infected with CMV or in patients who had received an organ transplant from someone who earlier had CMV infection HOW VALCYTE 450MG TABLET WORKS VALCYTE 450MG TABLET works by managing the multiplication of virus in human cells by decreasing its growth which results in inhibition of production of new virus thus managing and managing the spread of infection to other parts of the body in affected individuals. DIRECTIONS FOR USE Take VALCYTE 450MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF VALCYTE 450MG TABLET COMMON thrush & oral thrush (fungal infection) upper respiratory tract infection such as sinusitis, tonsillitis headache cough, shortness of breath abdominal pain, loss of appetite, nausea/vomiting, diarrhea, weight loss eczema (skin inflammation) tiredness, fever influenza signs of urine infection such as fever, passing urine more often, and/or pain (while passing urine) skin infection signs of mild allergic reaction such as red, itchy skin feeling depressed, anxious or confused trouble sleeping feeling numb/weak in hands/feet changes in sense of touch, tingling/tickling/pricking/burning sensation altered taste, chills eye inflammation/pain or sight problems ear pain signs of low blood pressure such as feeling dizzy/faint difficulty while swallowing constipation, wind, indigestion, stomach pain, swelling of abdomen mouth ulcers night sweats itching, rash hair loss back pain, muscle/joint pain, muscle spasms feeling dizzy, weak/generally unwell UNCOMMON feeling agitated tremor/shaking deafness irregular heartbeat red itchy welt, dry skin blood in urine chest pain RARE Stop taking VALCYTE 450MG TABLET and contact your doctor if you experience any of the following side effects: signs of allergic reaction (anaphylactic shock) such as raised, itchy skin rash, sudden swelling of throat, face, lips/mouth resulting in difficulty while swallowing/breathing, and/or sudden swelling of the hands, feet/ankles. signs of infection (due to low white blood cell count) such as sore throat, mouth ulcer, and/or fever signs of low red blood cell count such as shortness of breath, tiredness, palpitation, and/or pale skin signs of blood infection (sepsis) such as fever, chills, palpitation, confusion, and/or slurred speech signs of low platelet count such as bleeding/bruising, blood in urine/stools, and/or bleeding from gums severely low blood cell count pancreatitis (inflammation of pancreas) associated with severe stomach pain fits hallucinations abnormal thoughts/feelings, losing contact with reality failure of kidney function HOW TO MANAGE SIDE EFFECTS Constipation Try to eat high-fiber foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise (such as going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate managements for constipation.

Marketer BDR Pharmaceuticals Internationals Pvt SALT COMPOSITION Cabozantinib (40mg) Uses of Cabozanib Tablet Pancreatic cancer Small cell lung cancer Liver cancer Kidney cancer Thyroid cancer Blood cancer (Chronic myeloid leukaemia) Gastrointestinal stromal tumour Cancer of colon and rectum Non-small cell lung cancer Soft tissue sarcoma Chronic idiopathic myelofibrosis Breast cancer Product introduction Cabozanib 40mg Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer. Cabozanib 40mg Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. Take it exactly as advised by the doctor. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Fatigue, nausea, loss of appetite, taste change, and diarrhea are some of the common side effects of Cabozanib 40mg Tablet. It might cause high blood pressure, so the doctor may ask you for a regular check up of blood pressure. You must inform your doctor if you notice a severe skin reaction, such as skin rash or any pain, swelling, and redness of your hands and feet. Before taking Cabozanib 40mg Tablet, tell your doctor if you have heart disease, liver or kidney problems, or high blood pressure. Many other medicines can affect, or be affected by, this medicine, so let your healthcare team know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during the treatment with this drug is important to avoid pregnancy. Side effects of Cabozanib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Cabozanib Fatigue Nausea Diarrhea Vomiting Stomatitis (Inflammation of the mouth) High blood pressure Decreased appetite Taste change Low blood platelets Anemia (low number of red blood cells) Palmar-plantar erythrodysesthesia syndrome Decrease in body weight Increased liver enzymes Dyspepsia How to use Cabozanib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cabozanib 40mg Tablet is to be taken empty stomach. How Cabozanib Tablet works Cabozanib 40mg Tablet works by blocking the action of an abnormal protein that prompts multiplication of cancer cells, thereby slowing or stopping the spread of cancer cells. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Cabozanib 40mg Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Cabozanib 40mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Cabozanib 40mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. warnings Driving CONSULT YOUR DOCTOR It is not known whether Cabozanib 40mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. warnings Kidney SAFE IF PRESCRIBED Cabozanib 40mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Cabozanib 40mg Tablet is recommended. warnings Liver CAUTION Cabozanib 40mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Cabozanib 40mg Tablet may be needed. Please consult your doctor.

Marketer BDR Pharmaceuticals Internationals Pvt SALT COMPOSITION Cabozantinib (20mg) Uses of Cabozanib Tablet Pancreatic cancer Small cell lung cancer Liver cancer Kidney cancer Thyroid cancer Blood cancer (Chronic myeloid leukaemia) Gastrointestinal stromal tumour Cancer of colon and rectum Non-small cell lung cancer Soft tissue sarcoma Chronic idiopathic myelofibrosis Breast cancer Product introduction Cabozanib 20mg Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer. Cabozanib 20mg Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. Take it exactly as advised by the doctor. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Fatigue, nausea, loss of appetite, taste change, and diarrhea are some of the common side effects of Cabozanib 20mg Tablet. It might cause high blood pressure, so the doctor may ask you for a regular check up of blood pressure. You must inform your doctor if you notice a severe skin reaction, such as skin rash or any pain, swelling, and redness of your hands and feet. Before taking Cabozanib 20mg Tablet, tell your doctor if you have heart disease, liver or kidney problems, or high blood pressure. Many other medicines can affect, or be affected by, this medicine, so let your healthcare team know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during the treatment with this drug is important to avoid pregnancy. Side effects of Cabozanib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Cabozanib Fatigue Nausea Diarrhea Vomiting Stomatitis (Inflammation of the mouth) High blood pressure Decreased appetite Taste change Low blood platelets Anemia (low number of red blood cells) Palmar-plantar erythrodysesthesia syndrome Decrease in body weight Increased liver enzymes Dyspepsia How to use Cabozanib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cabozanib 20mg Tablet is to be taken empty stomach. How Cabozanib Tablet works Cabozanib 20mg Tablet works by blocking the action of an abnormal protein that prompts multiplication of cancer cells, thereby slowing or stopping the spread of cancer cells. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Cabozanib 20mg Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Cabozanib 20mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Cabozanib 20mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. warnings Driving CONSULT YOUR DOCTOR It is not known whether Cabozanib 20mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. warnings Kidney SAFE IF PRESCRIBED Cabozanib 20mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Cabozanib 20mg Tablet is recommended.

INTRODUCTION ABOUT I DOX 20MG INJECTION I DOX 20MG INJECTION contains Doxorubicin which belongs to the group of medicines called Anti-cancer agents. It is used to manage certain types of cancers. It is used either alone or along with other anti-cancer medicines. Cancer is a disease in which some of the cells of the body grow uncontrollably and spread to other parts of the body. Before receiving I DOX 20MG INJECTION, inform your doctor if you have or ever had heart disease, either before or during radiotherapy, had or having live or live-attenuated vaccinations, are currently taking or have recently taken Trastuzumab (used in the management of certain cancers). There are no adequate and well-controlled studies in pregnant women. Consult your doctor during breast-feeding before starting management with this medicine as it may pass through the breast milk and possibly harm your child. Consult your doctor for advice before receiving the medicine. The most common side effects of I DOX 20MG INJECTION are infection, lack of appetite, inflammation in the mouth, diarrhea, nausea, vomiting, reddening, swelling, pain, numbness and tingling in the palms and feet may also occur whilst being managed with this medicine. Hair loss is very common and may be quite severe, beard growth may stop in men, fever, feeling weak, chills, abnormal ECG (electrical trace of the heart) results, raised levels of liver enzymes (as detected by a blood test) can determine if the medicine is having an abnormal effect on your liver, weight increased in patients with early breast cancer. USES OF I DOX 20MG INJECTION Used to manage certain types of cancer HOW I DOX 20MG INJECTION WORKS I DOX 20MG INJECTION works by suppressing the activity of an enzyme (topoisomerase II) involved in the DNA multiplication of the cancer cells. On the other hand, this also forms harmful chemicals (free radicals) which cause damage to the DNA. This slowdown the growth of cancer cells and eventually works against them. DIRECTIONS FOR USE I DOX 20MG INJECTION will be administered intravenously (IV) into the vein by your doctor or nurse. Your doctor will administer the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF I DOX 20MG INJECTION COMMON infection lack of appetite inflammation in the mouth diarrhea nausea, vomiting hair loss beard growth may stop (in men) redness, swelling and blistering on the palms of the hands and soles of the feet (palmar-plantar erythrodysesthesia syndrome) chills weakness abnormal ECG raised levels of liver enzymes weight increased in patients with early breast cancer blood poisoning heart problems conjunctivitis (red watery eyes) lacrimation, excess tear production shortness of breath and swelling of the ankles increased heart rate inflammation of the throat and gullet stomach pain skin rashes, redness, hives nails and skin may appear darker than usual injection site reactions such as redness and swelling neutropenia thrombocytopenia malaise/asthenia infertility (in women) absence or decrease in sperm count (in men) UNCOMMON embolism (blockage in the bloodstream) RARE Stop receiving I DOX 20MG INJECTION and contact your doctor immediately if you experience any of the following side effects: dizzy, feverish, short of breath with a tight chest or throat or having an itchy rash anemia (low red blood cell count) decrease in white blood cell counts which in turn causes an increase in infections and a raised temperature (fever) platelets can be affected which could make a bruise or bleed more easily decreased activity in bone marrow reddening of urine dehydration inflammation of veins irritation or bleeding in the intestines inflammation of the lining of the stomach heartburn soreness or ulcers in the mouth