Combinib 250mg Tablet is used in the treatment of breast cancer. It works by stopping or slowing down the growth of cancer cells. It is either used alone or in combination with some other medicine to cure advanced-stage breast cancer. Combinib 250mg Tablet should be taken on an empty stomach or an hour before or 2 hours after a meal. The dose and duration vary according to the severity of your condition and your response to treatment. Take it exactly as prescribed to avoid serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include nausea, headache, back pain, and breathing difficulty. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. You may be asked for regular monitoring of blood pressure while taking this medicine. Inform your doctor if you notice a severe headache, confusion, problems with your eyesight, nausea, or vomiting. Your doctor may check your liver function before, during, and after treatment with this medicine. Before taking Combinib 250mg Tablet, let your doctor know if you have liver or kidney problems. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are taking. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details. Uses of Combinib Tablet Pancreatic cancer Small cell lung cancer Liver cancer Kidney cancer Thyroid cancer Blood cancer (Chronic myeloid leukaemia) Gastrointestinal stromal tumour Cancer of colon and rectum Non-small cell lung cancer Soft tissue sarcoma Chronic idiopathic myelofibrosis Breast cancer Side effects of Combinib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Combinib Abdominal pain Back pain Breathing problems Constipation Cough Diarrhea Fatigue Headache Hot flashes Increased bilirubin in the blood Insomnia (difficulty in sleeping) Joint pain Liver damage Loss of appetite Mucosal inflammation Nausea Pain in extremities Rash Stomatitis (Inflammation of the mouth) Vomiting Weakness Weight gain How to use Combinib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combinib 250mg Tablet is to be taken empty stomach. How Combinib Tablet works Combinib 250mg Tablet is an anti-cancer medication. It works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which are responsible for the over-proliferation of cells. This is how it inhibits the growth of cancerous cells causing downstream signaling pathways. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Combinib 250mg Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Combinib 250mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Combinib 250mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Combinib 250mg Tablet may cause side effects which could affect your ability to drive. warnings Kidney CAUTION Combinib 250mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Combinib 250mg Tablet may be needed. Please consult your doctor. Limited information is available on the use of Combinib 250mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease. warnings Liver CAUTION Combinib 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Combinib 250mg Tablet may be needed. Please consult your doctor. Limited information is available on the use of this medicine in patients with the severe liver disease.

Cytocarb 150mg Injection is used in the treatment of ovarian cancer and small cell lung cancer. It shows its working by stopping or slowing down the growth of cancer cells. Cytocarb 150mg Injection is given as an injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Nausea, vomiting, fatigue, and increased liver enzyme are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Inform your doctor if you notice fever, sore throat, chills, unusual bleeding or bruising, and dark urine. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. You must inform your doctor if you experience allergic reactions with injection such as skin rash, itching, and trouble breathing. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Uses of Cytocarb Injection Ovarian cancer Small cell lung cancer Cervical cancer Testicular cancer Cancer of colon and rectum Lung cancer Side effects of Cytocarb Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Cytocarb Nausea Vomiting Anemia (low number of red blood cells) Fatigue Low blood platelets Increased liver enzymes Decreased white blood cell count (neutrophils) Stomatitis (Inflammation of the mouth) Peripheral neuropathy (tingling and numbness of feet and hand) Diarrhea How to use Cytocarb Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Cytocarb Injection works Cytocarb 150mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Cytocarb 150mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Cytocarb 150mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Cytocarb 150mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Cytocarb 150mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. warnings Kidney CAUTION Cytocarb 150mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Cytocarb 150mg Injection may be needed. Please consult your doctor. Use of Cytocarb 150mg Injection is not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests may be advised while you are taking this medicine. warnings Liver SAFE IF PRESCRIBED Cytocarb 150mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Cytocarb 150mg Injection may not be needed in these patients. Please consult your doctor.

Marketer BDR Pharmaceuticals Internationals Pvt SALT COMPOSITION Cabozantinib (40mg) Uses of Cabozanib Tablet Pancreatic cancer Small cell lung cancer Liver cancer Kidney cancer Thyroid cancer Blood cancer (Chronic myeloid leukaemia) Gastrointestinal stromal tumour Cancer of colon and rectum Non-small cell lung cancer Soft tissue sarcoma Chronic idiopathic myelofibrosis Breast cancer Product introduction Cabozanib 40mg Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer. Cabozanib 40mg Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. Take it exactly as advised by the doctor. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Fatigue, nausea, loss of appetite, taste change, and diarrhea are some of the common side effects of Cabozanib 40mg Tablet. It might cause high blood pressure, so the doctor may ask you for a regular check up of blood pressure. You must inform your doctor if you notice a severe skin reaction, such as skin rash or any pain, swelling, and redness of your hands and feet. Before taking Cabozanib 40mg Tablet, tell your doctor if you have heart disease, liver or kidney problems, or high blood pressure. Many other medicines can affect, or be affected by, this medicine, so let your healthcare team know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during the treatment with this drug is important to avoid pregnancy. Side effects of Cabozanib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Cabozanib Fatigue Nausea Diarrhea Vomiting Stomatitis (Inflammation of the mouth) High blood pressure Decreased appetite Taste change Low blood platelets Anemia (low number of red blood cells) Palmar-plantar erythrodysesthesia syndrome Decrease in body weight Increased liver enzymes Dyspepsia How to use Cabozanib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cabozanib 40mg Tablet is to be taken empty stomach. How Cabozanib Tablet works Cabozanib 40mg Tablet works by blocking the action of an abnormal protein that prompts multiplication of cancer cells, thereby slowing or stopping the spread of cancer cells. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Cabozanib 40mg Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Cabozanib 40mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Cabozanib 40mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. warnings Driving CONSULT YOUR DOCTOR It is not known whether Cabozanib 40mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. warnings Kidney SAFE IF PRESCRIBED Cabozanib 40mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Cabozanib 40mg Tablet is recommended. warnings Liver CAUTION Cabozanib 40mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Cabozanib 40mg Tablet may be needed. Please consult your doctor.

Marketer BDR Pharmaceuticals Internationals Pvt SALT COMPOSITION Cabozantinib (60mg) Storage Store below 30°C Uses of Cabozanib Tablet Pancreatic cancer Small cell lung cancer Liver cancer Kidney cancer Thyroid cancer Blood cancer (Chronic myeloid leukaemia) Gastrointestinal stromal tumour Cancer of colon and rectum Non-small cell lung cancer Soft tissue sarcoma Chronic idiopathic myelofibrosis Breast cancer Product introduction Cabozanib 60 Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer. Cabozanib 60 Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. Take it exactly as advised by the doctor. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Fatigue, nausea, loss of appetite, taste change, and diarrhea are some of the common side effects of Cabozanib 60 Tablet. It might cause high blood pressure, so the doctor may ask you for a regular check up of blood pressure. You must inform your doctor if you notice a severe skin reaction, such as skin rash or any pain, swelling, and redness of your hands and feet. Before taking Cabozanib 60 Tablet, tell your doctor if you have heart disease, liver or kidney problems, or high blood pressure. Many other medicines can affect, or be affected by, this medicine, so let your healthcare team know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during the treatment with this drug is important to avoid pregnancy. Side effects of Cabozanib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Cabozanib Fatigue Nausea Diarrhea Vomiting Stomatitis (Inflammation of the mouth) High blood pressure Decreased appetite Taste change Low blood platelets Anemia (low number of red blood cells) Palmar-plantar erythrodysesthesia syndrome Decrease in body weight Increased liver enzymes Dyspepsia How to use Cabozanib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cabozanib 60 Tablet is to be taken empty stomach. How Cabozanib Tablet works Cabozanib 60 Tablet works by blocking the action of an abnormal protein that prompts multiplication of cancer cells, thereby slowing or stopping the spread of cancer cells. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Cabozanib 60 Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Cabozanib 60 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Cabozanib 60 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Marketer BDR Pharmaceuticals Internationals Pvt SALT COMPOSITION Cabozantinib (20mg) Uses of Cabozanib Tablet Pancreatic cancer Small cell lung cancer Liver cancer Kidney cancer Thyroid cancer Blood cancer (Chronic myeloid leukaemia) Gastrointestinal stromal tumour Cancer of colon and rectum Non-small cell lung cancer Soft tissue sarcoma Chronic idiopathic myelofibrosis Breast cancer Product introduction Cabozanib 20mg Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer. Cabozanib 20mg Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. Take it exactly as advised by the doctor. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Fatigue, nausea, loss of appetite, taste change, and diarrhea are some of the common side effects of Cabozanib 20mg Tablet. It might cause high blood pressure, so the doctor may ask you for a regular check up of blood pressure. You must inform your doctor if you notice a severe skin reaction, such as skin rash or any pain, swelling, and redness of your hands and feet. Before taking Cabozanib 20mg Tablet, tell your doctor if you have heart disease, liver or kidney problems, or high blood pressure. Many other medicines can affect, or be affected by, this medicine, so let your healthcare team know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during the treatment with this drug is important to avoid pregnancy. Side effects of Cabozanib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Cabozanib Fatigue Nausea Diarrhea Vomiting Stomatitis (Inflammation of the mouth) High blood pressure Decreased appetite Taste change Low blood platelets Anemia (low number of red blood cells) Palmar-plantar erythrodysesthesia syndrome Decrease in body weight Increased liver enzymes Dyspepsia How to use Cabozanib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cabozanib 20mg Tablet is to be taken empty stomach. How Cabozanib Tablet works Cabozanib 20mg Tablet works by blocking the action of an abnormal protein that prompts multiplication of cancer cells, thereby slowing or stopping the spread of cancer cells. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Cabozanib 20mg Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Cabozanib 20mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Cabozanib 20mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. warnings Driving CONSULT YOUR DOCTOR It is not known whether Cabozanib 20mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. warnings Kidney SAFE IF PRESCRIBED Cabozanib 20mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Cabozanib 20mg Tablet is recommended.

INTRODUCTION ABOUT TAXONAB 100MG INJECTION TAXONAB 100MG INJECTION contains Paclitaxel which belongs to a group of anti-cancer medicines called Taxanes. TAXONAB 100MG INJECTION is used to manage ovarian and breast cancer as a first line of therapy and as a second line of management when platinum containing medicines (such as cisplatin) or anthracyclines are insufficient to manage the disease in affected individuals. TAXONAB 100MG INJECTION is also used to manage advanced NSCLC (non-small cell lung cancer) when surgery/radiation therapy is not suitable. The medicine is also indicated for use to manage AIDS-related Kaposi’s sarcoma when other managements (such as anthracyclines) are insufficient to manage the disease in affected individuals. TAXONAB 100MG INJECTION is not recommended for use in patients allergic to paclitaxel and polyoxyethylated castor oil. It is also not recommended for use in patients with few white blood cells count and serious & uncontrolled infection. The medicine is also not used in patients suffering from severe liver disease. Before receiving TAXONAB 100MG INJECTION, inform your doctor if you had previously received radiation to your chest and/or suffering from thrombocytopenia (low platelet count)/acute infections (such as herpes zoster, chickenpox, herpes), kidney problems (such as chronic kidney disease), liver problems (such as mild/moderate hepatic impairment) and/or heart problems (such as severe coronary artery disease, myocardial infarction and arrhythmias). TAXONAB 100MG INJECTION is not recommended for use during pregnancy. Women of child-bearing potential should use effective contraception method while receiving TAXONAB 100MG INJECTION which should be continued for next-6 months after completing the management. The medicine is also not recommended for use in breastfeeding women. TAXONAB 100MG INJECTION is also not recommended for use in children and adolescents (aged below 18 years). The medicine can be used with caution in elderly patients (aged above 65 years) after consulting the doctor. The most common side effects of receiving TAXONAB 100MG INJECTION are minor allergic reactions (such as flushing, rash, itching), shortness of breath, sore throat/mouth ulcers, diarrhea, nausea, vomiting and/or loss of hair. Consult your doctor if any of these symptoms worsen. USES OF TAXONAB 100MG INJECTION Manage ovarian and breast cancer. Manage advanced NSCLC (non-small cell lung cancer) Manage AIDS-related Kaposi’s sarcoma in affected individuals. HOW TAXONAB 100MG INJECTION WORKS TAXONAB 100MG INJECTION works by interfering with the microtubule structures in the cell (substance which aids cancer cells to divide and multiply) thus inhibiting the growth of cancer cells and managing its spread in affected individuals. DIRECTIONS FOR USE TAXONAB 100MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF TAXONAB 100MG INJECTION COMMON minor allergic reactions such as flushing, rash and/or itching infections such as upper respiratory infection, urinary tract infection shortness of breath sore throat/mouth ulcers, sore and red mouth diarrhea, nausea, vomiting loss of hair pain in the muscles, cramps, joints fever, severe chills, headache, dizziness, tiredness, looking pale bleeding, bruising more easily than normal signs of peripheral neuropathy such as numbness, tingling/weakness in arms and legs temporary mild nail change and skin changes reactions at injection sites such as localized swelling, pain and/or redness of the skin. UNCOMMON septic shock (severe drop in blood pressure) due to infections racing heartbeat, rapid beating of the heart, respiratory distress, heart attack, heart block fatigue, sweating, fainting, significant allergic reactions, phlebitis (inflammation of a vein), swelling of the face, lips, mouth, tongue and/or throat back pain, chest pain, pain around hands and feet, chills, abdominal pain. RARE febrile neutropenia (type of fever) due to low white blood cell count associated with fever and increased risk of infection motor neuropathy (disease that affects your body’s motor nerves) pulmonary embolism (blockade of lung artery), lung fibrosis (damaged/scarred lung tissue), interstitial pneumonia (scarring of lung tissue), pleural effusion (build of fluid between lungs and chest) bowel obstruction, bowel perforation, inflammation of colon, inflammation of the pancreas (pancreatitis) skin redness peritonitis (inflammation of abdominal layer) fever, dehydration, weakness anaphylactic reactions (life threatening allergic reaction). HOW TO MANAGE SIDE EFFECTS Diarrhea: Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult your doctor and inform them if the symptom gets worse.

Marketer Getwell Pharma (I) Pvt Ltd SALT COMPOSITION Oxaliplatin (50mg) Storage Store below 30°C Uses of Xylotin Injection Ovarian cancer Small cell lung cancer Cervical cancer Testicular cancer Cancer of colon and rectum Lung cancer Product introduction Xylotin 50mg Injection is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells. Xylotin 50mg Injection is given as an injection into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Nausea, fatigue, vomiting, and diarrhea are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. It may cause some serious allergic reaction, inform your doctor if you notice sore lips or mouth ulcers, rash, itching and difficulty breathing. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It makes men infertile, hence men should take doctor advice about the freezing of sperm before the treatment. You must avoid driving after taking this medicine as it may cause dizziness. Side effects of Xylotin Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Xylotin Abdominal pain Injection site reaction Weight gain Conjunctivitis Fever Nosebleeds Hair loss Constipation Skin disorder Decreased appetite Infection Peripheral sensory neuropathy Inflammation of the nose Pain Increased transaminase level in blood Increased alkaline phosphatase level in blood Taste change Edema (swelling) Lacrimation disorder Allergic reaction Fatigue Nausea Vomiting Diarrhea Stomatitis (Inflammation of the mouth) Anemia (low number of red blood cells) Decreased white blood cell count (neutrophils) Low blood platelets Headache Breathlessness How to use Xylotin Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Xylotin Injection works Xylotin 50mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Xylotin 50mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Xylotin 50mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Xylotin 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Xylotin 50mg Injection may cause side effects which could affect your ability to drive. Xylotin 50mg Injection treatment may result in an increased risk of dizziness, nausea, and vomiting, and other neurological symptoms that affect walking and this may affect your ability to drive. warnings Kidney CAUTION Xylotin 50mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Xylotin 50mg Injection may be needed. Please consult your doctor. Limited information is available on the use of Xylotin 50mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease. warnings Liver CAUTION Xylotin 50mg Injection should be used with caution in patients with liver disease. Dose adjustment of Xylotin 50mg Injection may be needed. Please consult your doctor.

Marketer Getwell Pharma (I) Pvt Ltd SALT COMPOSITION Irinotecan (100mg) Storage Store below 25°C Uses of Rinowel Injection Ovarian cancer Small cell lung cancer Cervical cancer Cancer of colon and rectum Uses of Rinowel Injection Ovarian cancer Small cell lung cancer Cervical cancer Cancer of colon and rectum Side effects of Rinowel Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Rinowel Fatigue Nausea Vomiting Weakness Hair loss Fever Anemia (low number of red blood cells) Diarrhea Decreased white blood cell count (neutrophils) Decreased appetite Mucosal inflammation How to use Rinowel Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Rinowel Injection works Rinowel 100mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Rinowel 100mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Rinowel 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Rinowel 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Rinowel 100mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. warnings Kidney SAFE IF PRESCRIBED Rinowel 100mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Rinowel 100mg Injection may not be needed in these patients. Please consult your doctor. Use of this medicine is not recommended for patients on dialysis. warnings Liver CONSULT YOUR DOCTOR There is limited information available on the use of Rinowel 100mg Injection in patients with liver disease. Please consult your doctor.

Regonat Tablet is a Tyrosine kinase inhibitors used in the treatment of cancer of colon and rectum. Regonat Tablet should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include infection, low blood platelets, anemia, decreased appetite, hemorrhage, and high blood pressure. It can also cause voice change, diarrhea, stomatitis, vomiting, nausea, bilirubin in urine, increased liver enzyme, rash, weakness, pain, fever, mucosal inflammation, and weight loss. If any of these side effects bother you, let your doctor know. Regular blood tests are required to check your blood cells along with liver functioning.