Nitrocin 5ML Injection Marketer Samarth Life Sciences Pvt Ltd SALT COMPOSITION Nitroglycerin (5mg/ml) Salt Synonyms Glyceryl Trinitrate Storage Store below 30°C Uses of Nitrocin Injection Angina (heart-related chest pain) Heart Failure Treatment of Hypertension (high blood pressure) Coronary artery disease Hypertensive emergency Anal fissure Product introduction Nitrocin 5mg Injection is used to treat and prevent heart-related chest pain (angina) and hypertension (high blood pressure) during surgery. This medicine works by relaxing and widening blood vessels so blood can flow more easily to the heart. It has a very short-lived effect. Nitrocin 5mg Injection is given as an injection under the supervision of a doctor with careful blood pressure monitoring. This is given as a continuous infusion into a vein and should not be stopped abruptly. It should not be mixed with any other medication of any kind. The most common side effect of Nitrocin 5mg Injection is a headache which may be severe. This can sometimes be helped by drinking plenty of fluids and avoiding alcohol. You may also experience lightheadedness, which could increase your risk of having a fall. There are other, rarer side effects, some of them serious. Ask your doctor and read the leaflet which comes with the medicine to make sure you are keeping safe. Do not use Nitrocin 5mg Injection if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), or erectile dysfunction; or if you have anemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. It is best not to drink alcohol with this medicine as it increases some of the side effects. If you are affected by dizziness, avoid driving. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine. Benefits of Nitrocin Injection In Treatment of Hypertension (high blood pressure) Nitrocin 5mg Injection is used to treat hypertension in hypertensive emergencies. It rapidly dilates (widens) the blood vessels. This rapid vasodilation helps reduce blood pressure levels, relieving the strain on the heart and improving blood flow to vital organs. It is typically used in critical situations where immediate blood pressure reduction is necessary, such as severe high blood pressure that can lead to organ damage or other life-threatening complications. Side effects of Nitrocin Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Nitrocin Blurred vision Decreased blood pressure Dizziness Headache Increased heart rate Lightheadedness Paresthesia (tingling or pricking sensation) How to use Nitrocin Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Nitrocin Injection works Nitrocin 5mg Injection is a nitrate. It works by improving blood supply to heart and relaxing the blood vessels which decreases the oxygen demand of the heart and reduces its workload, thereby preventing/treating attacks of angina (chest pain). Relaxation of blood vessels lowers blood pressure. Safety advice warnings Alcohol UNSAFE Consuming alcohol while taking Nitrocin 5mg Injection may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction). warnings Pregnancy SAFE IF PRESCRIBED Nitrocin 5mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. warnings Breast feeding SAFE IF PRESCRIBED Nitrocin 5mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. warnings Driving UNSAFE Nitrocin 5mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. warnings Kidney SAFE IF PRESCRIBED Nitrocin 5mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nitrocin 5mg Injection may not be needed in these patients. Please consult your doctor. warnings Liver CONSULT YOUR DOCTOR There is limited information available on the use of Nitrocin 5mg Injection in patients with liver disease. Please consult your doctor.

BRILINTA 90MG TABLET 180'S ASTRAZENECA PHARMA INDIA LTD Salt: Ticagrelor (90mg) Description Brilinta 90mg Tablet belongs to a group of medicines called antiplatelet or blood thinners. It reduces the formation of harmful blood clots in blood vessels. This helps to prevent a heart attack or stroke in people with heart disease. Brilinta 90mg Tablet belongs to a group of medicines called antiplatelet or blood thinners. It reduces the formation of harmful blood clots in blood vessels. This helps to prevent a heart attack or stroke in people with heart disease. Benefits In Prevention of heart attack and stroke Brilinta 90mg Tablet is an antiplatelet medicine or blood thinner. It prevents blood from clotting inside the veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). Take this medicine regularly and make appropriate lifestyle changes to achieve maximum benefits. It is often prescribed along with a low dose of aspirin which also helps to prevent blood from clotting. Side Effects Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Brilinta Bleeding Breathlessness

Brilinta 90mg Tablet Marketer AstraZeneca SALT COMPOSITION Ticagrelor (90mg) Storage Store below 30°C Uses of Brilinta Tablet Heart attack Prevention of heart attack and stroke Unstable angina Product introduction Brilinta 90mg Tablet belongs to a group of medicines called antiplatelet or blood thinners. It reduces the formation of harmful blood clots in blood vessels, which helps to prevent heart attacks or strokes in people with heart disease. Brilinta 90mg Tablet is also used to treat people with a recent heart attack or severe heart-related chest pain (unstable angina) who have undergone stenting of the heart. It helps to prevent serious heart-related problems like having another heart attack, stroke, or formation of blood clots in stents in such people. Your doctor will also prescribe aspirin, another antiplatelet medicine, along with this medicine. Brilinta 90mg Tablet may be taken with or without food and should be taken regularly at the same time each day. It is important to keep taking it even if you feel well. If you stop taking this medicine, it may increase your chances of having another heart attack or stroke. The most common side effects of this medicine are dyspnea (breathlessness) and bleeding. If you cut or injure yourself, it may take longer than usual for the bleeding to stop. Such episodes of bleeding are usually mild and resolve on their own. Mild breathlessness caused by this medicine usually resolves on its own with continued treatment. Let your doctor know if bleeding persists or if the breathlessness worsens or does not go away. Brilinta 90mg Tablet is not suitable for some people. Do not take it if you are bleeding from anywhere in the body, such as a stomach ulcer or bleeding within the brain. It is also not recommended for people with liver diseases. Before using the medicine, inform your doctor of any such problems. Benefits of Brilinta Tablet In Prevention of heart attack and stroke Brilinta 90mg Tablet is an antiplatelet medicine or blood thinner. It prevents blood from clotting inside the veins and arteries, helping the blood flow freely around your body and preventing a heart attack or stroke (deep vein thrombosis or pulmonary embolism). To achieve maximum benefits, take this medicine regularly and make appropriate lifestyle changes. It is often prescribed with a low dose of aspirin, which also helps prevent blood from clotting. Side effects of Brilinta Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Brilinta Bleeding Breathlessness How to use Brilinta Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Brilinta 90mg Tablet may be taken with or without food, but it is better to take it at a fixed time. How Brilinta Tablet works Brilinta 90mg Tablet is an antiplatelet medication. It works by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots. This lowers the chance of heart attack or stroke. Safety advice warnings Alcohol CAUTION Caution is advised when consuming alcohol with Brilinta 90mg Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Brilinta 90mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Information regarding the use of Brilinta 90mg Tablet during breastfeeding is not available. Please consult your doctor. warnings Driving CONSULT YOUR DOCTOR It is not known whether Brilinta 90mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Dizziness, confusion, vertigo, and syncope have been reported in some patients. If you experience such symptoms, be cautious while driving or using machines. warnings Kidney SAFE IF PRESCRIBED Brilinta 90mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Brilinta 90mg Tablet is recommended. Limited information is available on the use of Brilinta 90mg Tablet in renal dialysis patients. warnings Liver SAFE IF PRESCRIBED Brilinta 90mg Tablet is safe to use in patients with liver disease. No dose adjustment of Brilinta 90mg Tablet is recommended. Use of Brilinta 90mg Tablet is not recommended in patients with severe liver disease.

Marketer Intas Pharmaceuticals Ltd SALT COMPOSITION Recombinant Human Erythropoietin Alfa (6000IU) Salt Synonyms Epoetin Alfa Storage Store in a refrigerator (2 - 8°C). Do not freeze. Uses of Renocel Injection Anemia due to chronic kidney disease Anemia due to cancer chemotherapy Product introduction Renocel 6000IU Injection is a medicine that helps your bone marrow to produce more red blood cells. It is used to treat a type of anemia caused by kidney disease. It is also used to treat anemia caused by cancer chemotherapy and by taking medicines to treat HIV. Renocel 6000IU Injection is given by injection either under the skin or into a vein which will be decided by your doctor. Usually, the injections are given by a nurse or doctor. The dose depends on your body weight and the cause of your anemia. Iron supplements both before and during treatment may make this treatment more effective. Renocel 6000IU Injection needs to be stored in a fridge but used at room temperature. The most common side effects of taking this medicine include nausea, vomiting, fever, and increased blood pressure. It may also cause flu-like symptoms such as headache, tiredness, dizziness and aches and pains. These side effects are most common at the start of treatment but if they persist your doctor may be able to suggest ways of preventing or reducing them. Tell your doctor straight away if you get any serious side effects, including seizures (fits). Sometimes this medicine can cause serious blood clots that need urgent medical attention. Before using Renocel 6000IU Injection you should tell your doctor if you have uncontrolled high blood pressure, heart disease, or gout (disease of joint pain). You should also tell him/her what other medicines you are taking in case they affect this treatment. Your blood pressure should be checked often during this treatment by you or your doctor. You may also need other regular medical tests to be sure this medicine is not causing harmful effects. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. Side effects of Renocel Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Renocel High blood pressure Nausea Vomiting Fever Rash Joint pain Headache Insomnia (difficulty in sleeping) Chills Cough Bone pain Muscle spasm Dizziness Vascular occlusion Injection site irritation Stomatitis (Inflammation of the mouth) Weight loss Decreased white blood cell count (lymphocytes) Increased glucose level in blood Blood clot in the blood vessels How to use Renocel Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Renocel Injection works Renocel 6000IU Injection is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Renocel 6000IU Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Renocel 6000IU Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Renocel 6000IU Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

INTRODUCTION ABOUT RITUXIREL 100 INJECTION RITUXIREL 100 INJECTION contains Rituximab which belongs to the group of medicines called Anticancer drugs. It is used to manage blood cancer (leukaemia) and lymph cancer (lymphoma). It can also be used to manage various auto-immune disease conditions such as rheumatoid arthritis, granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) and pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals). It is mostly used in combination with other cytotoxic anticancer agents to achieve better results. It is suitable for use both in adults and in children (aged 6 months or older). RITUXIREL 100 INJECTION will be administered to you only by an oncologist or a trained professional into your vein (as intravenous infusion). Before receiving RITUXIREL 100 INJECTION inform your doctor if you have any heart problems (such as chest pain, heart attack, heart failure or abnormal heartbeat). You must also inform your doctor if you currently have or previously had hepatitis B infection or any other mild infections (including minor cough and cold) as a precaution. RITUXIREL 100 INJECTION is not recommended for use in pregnant or breastfeeding women. Both men and women receiving RITUXIREL 100 INJECTION must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with RITUXIREL 100 INJECTION. The most common side effects of receiving this medicine are fever, chills, skin rashes with itching, shortness of breath and low blood pressure. Consult your doctor if any of these side effect worsens. USES OF RITUXIREL 100 INJECTION It is used to manage: Blood cancer (Chronic lymphocytic leukaemia) Lymph cancer (Non-Hodgkin’s Lymphoma) Rheumatoid arthritis (joint pain and inflammation) Granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) Pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals) HOW RITUXIREL 100 INJECTION WORKS RITUXIREL 100 INJECTION is a monoclonal antibody. It destroys the immune cells (B-cells) that triggers cancer formation. It also reduces the production of certain chemicals within the body (such as rheumatoid factor, T-cells, cytokines) that causes inflammation, pain and swelling which helps in managing various autoimmune diseases. DIRECTIONS FOR USE RITUXIREL 100 INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously). Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF RITUXIREL 100 INJECTION COMMON increased infections (bacterial, viral or fungal) low RBC, WBC and platelet counts in blood nausea, vomiting, diarrhea, stomach pain, constipation, indigestion mouth ulcers hair loss fever, chills, pneumonia, shingles, cold, sinusitis thrush, urinary tract infection headache, dizziness, tiredness, weakness hepatitis B infection high blood sugar and cholesterol levels weight loss, lack of appetite numbness, tingling, pricking, burning sensation on the skin restlessness, problems in falling asleep, anxiety, depression flushing (skin redness) eye inflammation or watery eyes ringing sound in the ears, ear pain uneven or fast heart rate, high or low blood pressure shortness of breath, runny nose, nasal itching and repeated sneezing increased sweating, night sweats muscle pain, joint pain, back pain, neck pain pain while passing urine fungal foot infection (athlete’s foot) tremors (shakiness) swelling of the hands or ankles UNCOMMON blood clotting problems changes in taste slow heart rate chest tightness and lung problems RARE Contact your doctor immediately if you experience any of the following side effects: fever, chills, shivering, nausea, vomiting, skin rashes with blisters and itching, flushing, pain at the infusion site, headache, tiredness, wheezing, high blood pressure, palpitations, swelling of throat or tongue, runny or itchy nose and chest pain fever, cough, sore throat, burning pain while passing urine, feeling weak or generally unwell signs of brain problem (such as memory loss, trouble thinking, difficulty in walking or vision problems) signs of severe skin reactions (such as severe skin blistering and redness that may appear on the on the mucous membranes, such as inside the mouth, the genital areas or the eyelids, with fever)

INTRODUCTION ABOUT RITUXIREL 500MG INJECTION RITUXIREL 500MG INJECTION contains Rituximab which belongs to the group of medicines called Anticancer drugs. It is used to manage blood cancer (leukaemia) and lymph cancer (lymphoma). It can also be used to manage various auto-immune disease conditions such as rheumatoid arthritis, granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) and pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals). It is mostly used in combination with other cytotoxic anticancer agents to achieve better results. It is suitable for use both in adults and in children (aged 6 months or older). RITUXIREL 500MG INJECTION will be administered to you only by an oncologist or a trained professional into your vein (as intravenous infusion). Before receiving RITUXIREL 500MG INJECTION inform your doctor if you have any heart problems (such as chest pain, heart attack, heart failure or abnormal heartbeat). You must also inform your doctor if you currently have or previously had hepatitis B infection or any other mild infections (including minor cough and cold) as a precaution. RITUXIREL 500MG INJECTION is not recommended for use in pregnant or breastfeeding women. Both men and women receiving RITUXIREL 500MG INJECTION must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with RITUXIREL 500MG INJECTION. The most common side effects of receiving this medicine are fever, chills, skin rashes with itching, shortness of breath and low blood pressure. Consult your doctor if any of these side effect worsens. USES OF RITUXIREL 500MG INJECTION It is used to manage: Blood cancer (Chronic lymphocytic leukaemia) Lymph cancer (Non-Hodgkin’s Lymphoma) Rheumatoid arthritis (joint pain and inflammation) Granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) Pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals) HOW RITUXIREL 500MG INJECTION WORKS RITUXIREL 500MG INJECTION is a monoclonal antibody. It destroys the immune cells (B-cells) that triggers cancer formation. It also reduces the production of certain chemicals within the body (such as rheumatoid factor, T-cells, cytokines) that causes inflammation, pain and swelling which helps in managing various autoimmune diseases. DIRECTIONS FOR USE RITUXIREL 500MG INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously). Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF RITUXIREL 500MG INJECTION COMMON increased infections (bacterial, viral or fungal) low RBC, WBC and platelet counts in blood nausea, vomiting, diarrhea, stomach pain, constipation, indigestion mouth ulcers hair loss fever, chills, pneumonia, shingles, cold, sinusitis thrush, urinary tract infection headache, dizziness, tiredness, weakness hepatitis B infection high blood sugar and cholesterol levels weight loss, lack of appetite numbness, tingling, pricking, burning sensation on the skin restlessness, problems in falling asleep, anxiety, depression flushing (skin redness) eye inflammation or watery eyes ringing sound in the ears, ear pain uneven or fast heart rate, high or low blood pressure shortness of breath, runny nose, nasal itching and repeated sneezing increased sweating, night sweats muscle pain, joint pain, back pain, neck pain pain while passing urine fungal foot infection (athlete’s foot) tremors (shakiness) swelling of the hands or ankles UNCOMMON blood clotting problems changes in taste slow heart rate chest tightness and lung problems RARE Contact your doctor immediately if you experience any of the following side effects: fever, chills, shivering, nausea, vomiting, skin rashes with blisters and itching, flushing, pain at the infusion site, headache, tiredness, wheezing, high blood pressure, palpitations, swelling of throat or tongue, runny or itchy nose and chest pain fever, cough, sore throat, burning pain while passing urine, feeling weak or generally unwell signs of brain problem (such as memory loss, trouble thinking, difficulty in walking or vision problems) signs of severe skin reactions (such as severe skin blistering and redness that may appear on the on the mucous membranes, such as inside the mouth, the genital areas or the eyelids, with fever) HOW TO MANAGE SIDE EFFECTS Constipation Try to eat more high-fibre foods such as fresh fruit, vegetables, cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate managements for constipation.

Aceptor contains Benazepril hydrochloride, an Angiotensin Converting Enzyme (ACE)-inhibitor. ACE inhibitors block an enzyme called Angiotensin Converting Enzyme (ACE) and helps in relaxing (dilatation) of blood vessels, thereby reducing blood pressure. Aceptor increases survival of patients with Dilated Cardiomyopathy (DCM) and Mitral valve disease (MMVD). It also reduces protein loss associated with Chronic Kidney Disease (CKD), decreases left ventricular wall thickness in Hypertrophic Cardiomyopathy (HCM) in cats and helps in the treatment of hypertension.

Paripher Eye Drop contains Phenylephrine Hydrochloride 10% and is primarily used in ophthalmology for its mydriatic (pupil-dilating) effects. This formulation is typically employed in clinical settings and is available by prescription.** ________________________________________ 🔍 Uses 1. Pupil Dilation (Mydriasis): Paripher is utilized to dilate the pupil during eye examinations and surgical procedures, allowing for a clearer view of the retina and other internal structures. 2. Treatment of Eye Redness and Irritation: As a decongestant, it constricts blood vessels in the eye, reducing redness and irritation caused by allergies or other factors. 3. Management of Uveitis: Phenylephrine's vasoconstrictive properties aid in managing inflammation associated with uveitis by decreasing blood flow to the affected area. 4. Adjunct in Nasal Decongestion: Though primarily an eye drop, Paripher's active ingredient is also utilized in nasal decongestants to relieve symptoms of the common cold. ________________________________________ ⚠️ Usage Instructions • Application: Instill the prescribed number of drops into the lower conjunctival sac of the eye. • Contact Lenses: Remove soft contact lenses before application and wait at least 10–15 minutes before reinsertion. • Avoid Contamination: Do not touch the dropper tip to any surface, including the eye, to prevent contamination. • Multiple Medications: If using other eye medications, wait at least 10 minutes before applying them to avoid dilution. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects: Temporary eye discomfort, such as stinging or burning sensations. • Serious Side Effects: Although rare, systemic absorption may lead to increased blood pressure, headache, or dizziness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.

Paripher Eye Drop is a pharmaceutical product containing Phenylephrine Hydrochloride 5%. It is primarily used in ophthalmology for various diagnostic and therapeutic purposes. ________________________________________ 🔍 Uses of Paripher Eye Drop 1. Pupil Dilation (Mydriasis): Paripher is commonly employed to dilate the pupil during eye examinations and surgical procedures, facilitating a clearer view of the retina and other internal structures. 2. Treatment of Eye Redness and Irritation: As a decongestant, it constricts blood vessels in the eye, reducing redness and irritation caused by allergies or other factors. 3. Management of Uveitis: Phenylephrine's vasoconstrictive properties aid in managing inflammation associated with uveitis by decreasing blood flow to the affected area. 4. Adjunct in Nasal Decongestion: Though primarily an eye drop, Paripher's active ingredient is also utilized in nasal decongestants to relieve symptoms of the common cold. ________________________________________ ⚠️ Usage Instructions • Application: Instill the prescribed number of drops into the lower conjunctival sac of the eye. • Contact Lenses: Remove soft contact lenses before application and wait at least 10–15 minutes before reinsertion. • Avoid Contamination: Do not touch the dropper tip to any surface, including the eye, to prevent contamination. • Multiple Medications: If using other eye medications, wait at least 10 minutes before applying them to avoid dilution. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects: Temporary eye discomfort, such as stinging or burning sensations. • Serious Side Effects: Although rare, systemic absorption may lead to increased blood pressure, headache, or dizziness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.