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General Medicine

Mucanix Injection is a brand of Acetylcysteine Injection, manufactured by American Remedies. Acetylcysteine is a mucolytic agent that helps in thinning and loosening mucus in the airways, making it easier to cough up and clear the airways. ________________________________________ ✅ Primary Uses Mucanix Injection is primarily used for: • Respiratory Disorders: Conditions such as chronic bronchitis, asthma, and cystic fibrosis, where there is excessive mucus production. • Paracetamol (Acetaminophen) Overdose: As an antidote to prevent liver damage when administered within 8 hours of overdose. ________________________________________ ⚙️ Mechanism of Action Acetylcysteine works by: • Breaking down mucus: It reduces the viscosity of mucus, facilitating easier expectoration. • Restoring glutathione levels: In cases of paracetamol overdose, it replenishes glutathione, a vital antioxidant, aiding in detoxification and protecting the liver. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Allergy: Do not use if allergic to acetylcysteine or any of its components. • Asthma: Use with caution in patients with asthma; monitoring is required. • Pregnancy and Breastfeeding: Consult a doctor before use during pregnancy or breastfeeding. Common Side Effects: • Nausea • Vomiting • Rash • Fever • Headache Serious Side Effects: • Anaphylactic reactions (rare) • Hypotension • Tachycardia If you experience any of these serious side effects, seek immediate medical attention.

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General Medicine

Dopacan Injection is a brand of Dopamine Hydrochloride, a potent vasopressor and inotropic agent used in critical care settings to manage various cardiovascular conditions. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dopacan Injection is indicated for: • Shock Management: Including septic shock, cardiogenic shock, and hypovolemic shock. • Acute Heart Failure: To improve cardiac output and perfusion. • Severe Hypotension: Especially in patients unresponsive to volume resuscitation. • Renal Protection: To enhance renal blood flow and urine output in certain critically ill patients. Dopamine works by stimulating dopaminergic and beta-adrenergic receptors, leading to increased heart rate, contractility, and renal perfusion. At higher doses, it also stimulates alpha-adrenergic receptors, causing vasoconstriction and increased blood pressure. ________________________________________ ⚙️ Dosage and Administration Dopacan Injection is administered intravenously, with the dosage tailored to the patient's condition and response: • Low Dose (1–5 mcg/kg/min): Primarily stimulates dopaminergic receptors, increasing renal blood flow and urine output. • Medium Dose (5–15 mcg/kg/min): Stimulates beta-1 adrenergic receptors, enhancing heart rate and contractility. • High Dose (15–50 mcg/kg/min): Stimulates alpha-1 adrenergic receptors, leading to vasoconstriction and increased blood pressure. Continuous monitoring of blood pressure, heart rate, and urine output is essential during administration. ________________________________________ ⚠️ Precautions and Contraindications Before using Dopacan Injection, inform your healthcare provider if you have: • Allergies to dopamine or other components of the injection. • A history of heart rhythm disorders or coronary artery disease. • Pheochromocytoma (a rare tumor of the adrenal glands). • Diabetes, asthma, or sulfite allergies. • Circulatory disorders such as Raynaud's disease or Buerger's disease. • Recent use of monoamine oxidase inhibitors (MAOIs). This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. ________________________________________ 💊 Side Effects Common side effects may include: • Palpitations or increased heart rate. • Nausea and vomiting. • Headache. • Difficulty breathing. • Gangrene (in rare cases, due to excessive vasoconstriction). Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.

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Eye Care

Biotrav-T (Travoprost and Timolol Maleate) Ophthalmic Solution is a prescription eye drop used to manage elevated intraocular pressure (IOP) in individuals with open-angle glaucoma or ocular hypertension. It combines two medications—travoprost (a prostaglandin analog) and timolol maleate (a non-selective beta-blocker)—to reduce IOP through complementary mechanisms. ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common form of glaucoma characterized by gradual loss of vision due to increased IOP. • Ocular Hypertension: Elevated IOP without optic nerve damage, which can lead to glaucoma if untreated. ________________________________________ 💊 Dosage and Administration • Recommended Dosage: Instill one drop into the affected eye(s) once daily, preferably in the evening. • Application Tips: o Wash hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Active or suspected ocular infections. o History of hypersensitivity to beta-blockers. • Cautions: o Use with caution in patients with cardiovascular or pulmonary diseases, as timolol may exacerbate conditions like asthma, bradycardia, or heart block. o Monitor for potential systemic absorption effects, including hypotension or bradycardia. o Consult a healthcare provider before use if pregnant, planning to become pregnant, or breastfeeding. ________________________________________

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Eye Care

Timipar (Timolol Maleate 0.5%) Ophthalmic Solution is a prescription eye drop used to manage elevated intraocular pressure (IOP) in conditions such as open-angle glaucoma and ocular hypertension. By reducing the production of fluid within the eye, it helps lower IOP, thereby reducing the risk of optic nerve damage and potential vision loss. ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common form of glaucoma where the drainage angle in the eye remains open, but the trabecular meshwork is partially blocked, leading to increased IOP. • Ocular Hypertension: A condition characterized by higher-than-normal IOP without any signs of glaucoma damage. ________________________________________ 💊 Dosage and Administration • Typical Dosage: Instill one drop of the 0.5% solution into the affected eye(s) twice daily. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. o After instilling the drop, gently press the corner of your eye (near the nose) for 1–2 minutes to prevent the medication from draining out. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Bronchial asthma or a history of bronchial asthma. o Severe chronic obstructive pulmonary disease (COPD). o Sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock. • Cautions: o Use with caution in patients with a history of heart disease, diabetes, or thyroid disorders, as beta-blockers can mask symptoms of hypoglycemia and hyperthyroidism. o Monitor for potential additive effects when used with other systemic beta-blockers. ________________________________________ 🧪 Mechanism of Action Timolol is a non-selective beta-adrenergic antagonist (beta-blocker) that reduces aqueous humor production in the eye, leading to a decrease in IOP. Its onset of action is typically within 20 minutes, with effects lasting up to 24 hours.

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Eye Care

Timipar (Timolol Maleate 0.25%) eye drops are a prescription medication primarily used to manage elevated intraocular pressure (IOP) associated with conditions like open-angle glaucoma and ocular hypertension. By reducing the production of aqueous humor, the fluid inside the eye, Timolol helps lower IOP, thereby reducing the risk of optic nerve damage and potential vision loss . ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common type of glaucoma where the drainage angle in the eye remains open, but the trabecular meshwork is partially blocked, leading to increased IOP. • Ocular Hypertension: A condition characterized by higher-than-normal IOP without any signs of glaucoma damage. ________________________________________ 💊 Dosage and Administration • Typical Dosage: Instill one drop of the 0.25% solution into the affected eye(s) once or twice daily, as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them . ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Bronchial asthma or a history of bronchial asthma. o Severe chronic obstructive pulmonary disease (COPD). • Sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock . • Cautions: o Use with caution in patients with a history of heart disease, diabetes, or thyroid disorders, as beta-blockers can mask symptoms of hypoglycemia and hyperthyroidism. o Monitor for potential additive effects when used with other systemic beta-blockers . ________________________________________ 🧪 Mechanism of Action Timolol is a non-selective beta-adrenergic antagonist (beta-blocker) that reduces aqueous humor production in the eye, leading to a decrease in IOP. Its onset of action is typically within 20 minutes, with effects lasting up to 24 hours .

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General Medicine

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

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General Medicine

Nitrocan 25 Injection is a brand of Nitroglycerin Injection 25 mg/5 mL, manufactured by American Remedies. It is primarily used in hospital settings for the management of certain cardiovascular conditions. ________________________________________ ✅ Primary Uses Nitrocan 25 Injection is indicated for: • Angina Pectoris: To treat and prevent chest pain caused by reduced blood flow to the heart. • Acute Myocardial Infarction (Heart Attack): To alleviate chest pain and improve blood flow to the heart muscle. Hypertension During Surgery: To control high blood pressure during and after surgical procedures. • Congestive Heart Failure: To reduce the workload on the heart and improve symptoms. ________________________________________ ⚙️ Mechanism of Action Nitroglycerin is a nitrate that, once administered, is converted into nitric oxide in the body. This leads to the relaxation and dilation of blood vessels, improving blood flow and reducing the heart's workload. ________________________________________ ⚠️ Precautions • Contraindications: Should not be used in patients with severe anemia, hypotension, or those taking medications for erectile dysfunction (e.g., sildenafil, tadalafil) due to the risk of a significant drop in blood pressure. • Monitoring: Requires careful monitoring of blood pressure and heart rate during administration. • Administration: Administered intravenously under medical supervision; dosage and duration are determined by the healthcare provider. ________________________________________ 💊 Common Side Effects • Headache • Dizziness or lightheadedness • Hypotension (low blood pressure) • Nausea or vomiting • Flushing

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General Medicine

MNOphyllin Injection is a brand of Aminophylline Injection, manufactured by American Remedies. Aminophylline is a bronchodilator that works by relaxing the muscles of the air passages in the lungs, making it easier to breathe. ________________________________________ ✅ Primary Uses MNOphyllin Injection is primarily used for: • Asthma: A chronic condition where the airways become inflamed and narrow, leading to difficulty in breathing. • Chronic Obstructive Pulmonary Disease (COPD): A group of lung diseases that block airflow and make breathing difficult. • Bronchospasm: A condition where the muscles around the airways tighten, leading to wheezing and shortness of breath. It is administered intravenously in a hospital setting under medical supervision. ________________________________________ ⚙️ Mechanism of Action Aminophylline works by: • Relaxing the bronchial muscles: This leads to the widening of the air passages, making it easier to breathe. • Increasing the strength of the diaphragm: This enhances the ability to breathe effectively. • Reducing airway responsiveness to irritants: This helps in decreasing inflammation and bronchoconstriction. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Medical History: Inform your doctor if you have a history of heart disease, liver or kidney disorders, or seizures. • Pregnancy and Breastfeeding: Consult your doctor before use if pregnant or breastfeeding. • Drug Interactions: Certain medications can interact with Aminophylline, so it's essential to inform your healthcare provider about all medicines you are taking. Common Side Effects: • Nausea • Vomiting • Headache • Restlessness • Dizziness Serious Side Effects: • Irregular heartbeats • Seizures • Severe allergic reactions If you experience any of these serious side effects, seek immediate medical attention.

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General Medicine

Milrican 10 is a brand of Milrinone Lactate Injection, manufactured by American Remedies. Milrinone is a phosphodiesterase-3 (PDE3) inhibitor that serves as both an inotropic agent and a vasodilator. ________________________________________ ✅ Primary Uses of Milrican 10 Milrican 10 is indicated for the short-term intravenous treatment of: • Severe congestive heart failure: Particularly in patients unresponsive to conventional therapies. • Acute decompensated heart failure: Including low output states following cardiac surgery. It is commonly used in intensive care units or during cardiac procedures to support heart function. ________________________________________ ⚙️ Mechanism of Action Milrinone works by inhibiting PDE3, leading to increased cyclic AMP (cAMP) levels in cardiac and vascular smooth muscle cells. This results in: • Increased myocardial contractility: Enhancing the heart's ability to pump blood. • Vasodilation: Relaxing blood vessels, which reduces the heart's workload and improves blood flow. ________________________________________ ⚠️ Important Considerations • Administration: Milrican 10 should only be administered intravenously under the supervision of a healthcare professional. • Monitoring: Patients receiving Milrican 10 require close monitoring of blood pressure, heart rate, and kidney function. • Contraindications: Not recommended for patients with severe dehydration, electrolyte imbalances, or known hypersensitivity to milrinone. • Pregnancy and Breastfeeding: Consult a doctor before use if pregnant or breastfeeding.

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