Dopacan Injection is a brand of Dopamine Hydrochloride, a potent vasopressor and inotropic agent used in critical care settings to manage various cardiovascular conditions. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dopacan Injection is indicated for: • Shock Management: Including septic shock, cardiogenic shock, and hypovolemic shock. • Acute Heart Failure: To improve cardiac output and perfusion. • Severe Hypotension: Especially in patients unresponsive to volume resuscitation. • Renal Protection: To enhance renal blood flow and urine output in certain critically ill patients. Dopamine works by stimulating dopaminergic and beta-adrenergic receptors, leading to increased heart rate, contractility, and renal perfusion. At higher doses, it also stimulates alpha-adrenergic receptors, causing vasoconstriction and increased blood pressure. ________________________________________ ⚙️ Dosage and Administration Dopacan Injection is administered intravenously, with the dosage tailored to the patient's condition and response: • Low Dose (1–5 mcg/kg/min): Primarily stimulates dopaminergic receptors, increasing renal blood flow and urine output. • Medium Dose (5–15 mcg/kg/min): Stimulates beta-1 adrenergic receptors, enhancing heart rate and contractility. • High Dose (15–50 mcg/kg/min): Stimulates alpha-1 adrenergic receptors, leading to vasoconstriction and increased blood pressure. Continuous monitoring of blood pressure, heart rate, and urine output is essential during administration. ________________________________________ ⚠️ Precautions and Contraindications Before using Dopacan Injection, inform your healthcare provider if you have: • Allergies to dopamine or other components of the injection. • A history of heart rhythm disorders or coronary artery disease. • Pheochromocytoma (a rare tumor of the adrenal glands). • Diabetes, asthma, or sulfite allergies. • Circulatory disorders such as Raynaud's disease or Buerger's disease. • Recent use of monoamine oxidase inhibitors (MAOIs). This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. ________________________________________ 💊 Side Effects Common side effects may include: • Palpitations or increased heart rate. • Nausea and vomiting. • Headache. • Difficulty breathing. • Gangrene (in rare cases, due to excessive vasoconstriction). Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.

Dobutacan 12 Injection is a brand of Dobutamine Hydrochloride 12.5 mg/mL, a synthetic catecholamine used in critical care settings to support heart function. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dobutacan 12 Injection is indicated for: • Cardiac Decompensation: Acute heart failure due to conditions like myocardial infarction, cardiomyopathies, or post-cardiac surgery. • Cardiogenic Shock: A state of low cardiac output leading to inadequate tissue perfusion. • Septic Shock: A severe infection causing low blood pressure and organ dysfunction. • Stress Echocardiography: As a pharmacological agent to assess coronary artery disease when exercise is not feasible. It works by stimulating beta-1 adrenergic receptors, increasing heart contractility and stroke volume, thereby improving cardiac output. ________________________________________ ⚙️ Dosage and Administration Dobutacan 12 Injection is administered intravenously in a hospital setting. The typical dosage ranges from 2.5 to 10 mcg/kg/min, adjusted based on the patient's response. In some cases, doses up to 20 mcg/kg/min may be required. ________________________________________ ⚠️ Precautions and Contraindications Before using Dobutacan 12 Injection, inform your healthcare provider if you have: • Allergies to dobutamine or other components of the injection. • A history of arrhythmias or heart disease. • Kidney or liver problems. • A history of stroke or blood clots. This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. It is usually given as an intramuscular (IM) or intravenous (IV) injection. ________________________________________ 💊 Side Effects Common side effects may include: • Headache • Nausea or vomiting • Dizziness or lightheadedness • Injection site reactions (pain, redness, or swelling) Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.

ALFADOFOX 250 contains Methyldopa Tablets IP 250 mg used plain or with other medications to treat high blood pressure ALFADOFOX 250 contains Methyldopa Tablets IP 250 mg used plain or with other medications to treat high blood pressure ALFADOFOX 250 contains Methyldopa Tablets IP 250 mg, which is a medication used primarily to treat high blood pressure (hypertension). 💊 Drug Name: Methyldopa 250 mg (brand: ALFADOFOX 250) 🔹 Drug Class: Antihypertensive agent Central alpha-2 adrenergic agonist 🔹 What It’s Used For: Methyldopa is used to lower blood pressure, especially in: Essential (primary) hypertension Pregnancy-induced hypertension (pre-eclampsia/eclampsia) — it's one of the safest options during pregnancy ⚙️ How It Works: Methyldopa works by: Stimulating alpha-2 adrenergic receptors in the central nervous system This leads to reduced sympathetic (nerve) signals, causing blood vessels to relax and heart rate to slow down As a result, blood pressure decreases

Timipar (Timolol Maleate 0.5%) Ophthalmic Solution is a prescription eye drop used to manage elevated intraocular pressure (IOP) in conditions such as open-angle glaucoma and ocular hypertension. By reducing the production of fluid within the eye, it helps lower IOP, thereby reducing the risk of optic nerve damage and potential vision loss. ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common form of glaucoma where the drainage angle in the eye remains open, but the trabecular meshwork is partially blocked, leading to increased IOP. • Ocular Hypertension: A condition characterized by higher-than-normal IOP without any signs of glaucoma damage. ________________________________________ 💊 Dosage and Administration • Typical Dosage: Instill one drop of the 0.5% solution into the affected eye(s) twice daily. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. o After instilling the drop, gently press the corner of your eye (near the nose) for 1–2 minutes to prevent the medication from draining out. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Bronchial asthma or a history of bronchial asthma. o Severe chronic obstructive pulmonary disease (COPD). o Sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock. • Cautions: o Use with caution in patients with a history of heart disease, diabetes, or thyroid disorders, as beta-blockers can mask symptoms of hypoglycemia and hyperthyroidism. o Monitor for potential additive effects when used with other systemic beta-blockers. ________________________________________ 🧪 Mechanism of Action Timolol is a non-selective beta-adrenergic antagonist (beta-blocker) that reduces aqueous humor production in the eye, leading to a decrease in IOP. Its onset of action is typically within 20 minutes, with effects lasting up to 24 hours.

Timipar (Timolol Maleate 0.25%) eye drops are a prescription medication primarily used to manage elevated intraocular pressure (IOP) associated with conditions like open-angle glaucoma and ocular hypertension. By reducing the production of aqueous humor, the fluid inside the eye, Timolol helps lower IOP, thereby reducing the risk of optic nerve damage and potential vision loss . ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common type of glaucoma where the drainage angle in the eye remains open, but the trabecular meshwork is partially blocked, leading to increased IOP. • Ocular Hypertension: A condition characterized by higher-than-normal IOP without any signs of glaucoma damage. ________________________________________ 💊 Dosage and Administration • Typical Dosage: Instill one drop of the 0.25% solution into the affected eye(s) once or twice daily, as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them . ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Bronchial asthma or a history of bronchial asthma. o Severe chronic obstructive pulmonary disease (COPD). • Sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock . • Cautions: o Use with caution in patients with a history of heart disease, diabetes, or thyroid disorders, as beta-blockers can mask symptoms of hypoglycemia and hyperthyroidism. o Monitor for potential additive effects when used with other systemic beta-blockers . ________________________________________ 🧪 Mechanism of Action Timolol is a non-selective beta-adrenergic antagonist (beta-blocker) that reduces aqueous humor production in the eye, leading to a decrease in IOP. Its onset of action is typically within 20 minutes, with effects lasting up to 24 hours .

Ondican 4 Injection, also known by the generic name Ondansetron 4 mg Injection, is an antiemetic medication primarily used to prevent and treat nausea and vomiting associated with various medical conditions and treatments. Common Uses 1. Chemotherapy-Induced Nausea and Vomiting (CINV): Ondican 4 is administered to prevent nausea and vomiting caused by chemotherapy. It is typically given 30 minutes before the start of chemotherapy sessions. 2. Radiation Therapy-Induced Nausea and Vomiting: It is used to prevent nausea and vomiting associated with radiation therapy, usually administered 1–2 hours before treatment. 3. Postoperative Nausea and Vomiting (PONV): Ondican 4 helps prevent and treat nausea and vomiting following surgery. It is administered immediately before or within 2 hours after surgery. 4. Other Causes of Nausea and Vomiting: It may also be used to manage nausea and vomiting due to other causes, such as gastroenteritis or certain medical conditions. Mechanism of Action Ondican 4 works by blocking the action of serotonin, a chemical in the body that can trigger nausea and vomiting. By inhibiting serotonin receptors in the brain and gastrointestinal tract, it effectively prevents these symptoms. Administration Ondican 4 Injection is administered intravenously (IV) by a healthcare professional in a hospital or clinic setting. The dosage and timing depend on the specific condition being treated and the patient's medical history. Side Effects Common side effects may include: • Headache • Constipation • Dizziness • Fatigue • Injection site reactions These side effects are generally mild and temporary. However, if they persist or worsen, consult your healthcare provider. Precautions Before receiving Ondican 4, inform your doctor if you have: • Liver disease • Heart problems • Electrolyte imbalances • Blockage in the stomach or intestines Additionally, disclose any other medications you are taking, as interactions may occur. Pregnant or breastfeeding individuals should consult their healthcare provider before use.

Ondican 2 Injection is a brand of Ondansetron 2 mg/2 mL Injection, manufactured by American Remedies. Ondansetron is a 5-HT₃ receptor antagonist commonly used as an antiemetic to prevent and treat nausea and vomiting associated with various medical conditions. ________________________________________ ✅ Primary Uses Ondican 2 Injection is indicated for: • Chemotherapy-Induced Nausea and Vomiting (CINV): To prevent and treat nausea and vomiting caused by cancer chemotherapy. Radiotherapy-Induced Nausea and Vomiting (RINV): To prevent and treat nausea and vomiting associated with radiation therapy. Postoperative Nausea and Vomiting (PONV): To prevent and treat nausea and vomiting following surgical procedures. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Ondansetron works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting. It specifically inhibits serotonin receptors in the chemoreceptor trigger zone (CTZ) in the brain, thereby preventing the sensation of nausea and the act of vomiting. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Allergy: Do not use if allergic to ondansetron or other 5-HT₃ receptor antagonists. • Cardiac Conditions: Use with caution in patients with a history of heart problems, as ondansetron may affect heart rhythm. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Headache • Constipation • DizzinessFatigue Serious Side Effects: • Allergic reactions (rash, itching, swelling) Severe dizziness or fainting • Irregular heartbeat Seek immediate medical attention if any serious side effects occur.

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

Labecanol Injection 4 ml belongs to the group of anti-hypertensive medicines called beta-blocking agents used to treat severe hypertension (high blood pressure). Additionally, American Labecanol Injection 4 ml is used to control high blood pressure in pregnancy and during anaesthesia. Labecanol Injection 4 ml contains ‘labetalol’ that works by blocking the receptors in the cardiovascular (circulatory) system, this helps in decreasing the blood pressure in the blood vessels. Thus, it helps lower the blood pressure to normal. In some cases, American Labecanol Injection 4 ml may cause common side effects such as postural hypotension, dizziness, fatigue, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.