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Eye Care

Biotrav-T (Travoprost and Timolol Maleate) Ophthalmic Solution is a prescription eye drop used to manage elevated intraocular pressure (IOP) in individuals with open-angle glaucoma or ocular hypertension. It combines two medications—travoprost (a prostaglandin analog) and timolol maleate (a non-selective beta-blocker)—to reduce IOP through complementary mechanisms. ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common form of glaucoma characterized by gradual loss of vision due to increased IOP. • Ocular Hypertension: Elevated IOP without optic nerve damage, which can lead to glaucoma if untreated. ________________________________________ 💊 Dosage and Administration • Recommended Dosage: Instill one drop into the affected eye(s) once daily, preferably in the evening. • Application Tips: o Wash hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Active or suspected ocular infections. o History of hypersensitivity to beta-blockers. • Cautions: o Use with caution in patients with cardiovascular or pulmonary diseases, as timolol may exacerbate conditions like asthma, bradycardia, or heart block. o Monitor for potential systemic absorption effects, including hypotension or bradycardia. o Consult a healthcare provider before use if pregnant, planning to become pregnant, or breastfeeding. ________________________________________

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Eye Care

FZ-3 Eye-Ear Drops containing Fluconazole are primarily used to treat fungal infections of the eyes and ears. Fluconazole is an antifungal medication that works by inhibiting the growth of fungi. 🔹 Primary Uses Fungal Eye Infections (Ophthalmic Fungal Infections) Fluconazole in eye drop form is used to treat fungal infections of the eye, such as fungal keratitis or endophthalmitis, which can cause inflammation, pain, and potentially lead to vision loss if left untreated. Fungal Ear Infections (Otomycosis) FZ-3 can be used for treating fungal ear infections, also known as otomycosis, which is often caused by fungi like Aspergillus or Candida. Symptoms include itching, pain, and discharge from the ear canal. 🔹 How It Works Fluconazole is an antifungal agent that works by inhibiting the fungal enzyme lanosterol 14α-demethylase, which is involved in the synthesis of ergosterol, an essential component of the fungal cell membrane. By blocking this enzyme, fluconazole disrupts the fungal cell membrane, leading to fungal cell death or inhibition of growth. ⚠️ Common Side Effects Eye: Mild eye irritation or burning sensation upon application Blurred vision (temporary) Redness or stinging in the eyes Ear: Mild ear irritation Ear itching or discomfort after application Temporary hearing changes (rare) If any of these side effects persist or worsen, consult your healthcare provider. 🔹 Usage Tips Dosage: Typically, 1–2 drops are applied to the affected eye or ear 2–3 times daily, as prescribed by your doctor. Application Instructions: Wash your hands thoroughly before applying the drops. For the eyes: Tilt your head back and gently pull down the lower eyelid to form a pocket. Instill the prescribed number of drops and gently close your eye for a few seconds. For the ears: Tilt your head to one side, apply the drops into the ear canal, and gently massage the ear to help the drops penetrate. If you are using other medications for the eyes or ears, wait about 5 minutes between applying each medication. Contact Lenses: If you wear contact lenses, remove them before applying the drops to avoid any contamination. You can reinsert your lenses after 15 minutes. 🔹 Precautions Allergies: If you have a known allergy to fluconazole or other azole antifungals, do not use the drops. Pregnancy and Breastfeeding: Fluconazole should be used with caution in pregnancy, particularly during the first trimester. Always consult your doctor if you are pregnant or breastfeeding. Underlying Conditions: Inform your healthcare provider if you have any liver or kidney diseases, as these conditions may affect how the medication works in your body. Systemic Absorption: Although FZ-3 is used topically, there is a possibility of systemic absorption. Monitor for any systemic side effects, especially with prolonged use.

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Eye Care

Dorzopar Eye Drops containing Dorzolamide 2% are primarily used to lower intraocular pressure (IOP) in individuals with glaucoma or ocular hypertension (high eye pressure). Here's a detailed breakdown of its uses: 🔹 Primary Uses Open-Angle Glaucoma Dorzolamide is a carbonic anhydrase inhibitor that helps reduce the production of aqueous humor (the fluid inside the eye). By decreasing the amount of fluid produced, it lowers the intraocular pressure (IOP), which is important in treating open-angle glaucoma. Glaucoma is a condition where high eye pressure can damage the optic nerve and lead to vision loss. Ocular Hypertension Dorzopar is also used for the treatment of ocular hypertension, a condition in which the eye pressure is elevated but glaucoma has not yet developed. Lowering eye pressure helps prevent the progression to glaucoma. 🔹 How It Works Dorzolamide works by inhibiting the carbonic anhydrase enzyme in the eye. This enzyme is involved in the production of aqueous humor. By blocking this enzyme, Dorzolamide reduces the amount of fluid produced inside the eye, which in turn lowers the eye pressure. ⚠️ Common Side Effects Eye irritation, burning, or stinging upon application Blurred vision (temporary) Redness in the eyes or foreign body sensation Dry eyes or increased tear production Headaches or dizziness (in some cases) Taste disturbance (a bitter taste in the mouth) 🔹 Usage Tips Dosage: Typically, 1 drop in each affected eye, twice daily (morning and evening), or as prescribed by your healthcare provider. Application Instructions: Wash your hands thoroughly before applying the drops. Tilt your head back slightly and pull down your lower eyelid to form a small pocket. Place one drop in the pocket without touching the dropper tip to your eye. Gently close your eye and blink a few times to help spread the medication. If using other eye medications, wait 5–10 minutes between applications. Contact Lenses: Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them. 🔹 Precautions Kidney or Liver Problems: Since Dorzolamide is metabolized in the body, it should be used with caution in individuals with kidney or liver issues. Pregnancy and Breastfeeding: Consult your doctor before using this medication if you are pregnant or breastfeeding, as the safety of Dorzolamide during pregnancy or while breastfeeding has not been fully established. Eye Infections: Be cautious if you have an eye infection, as Dorzolamide may not be suitable for some active infections. Systemic Effects: While Dorzolamide is generally applied locally to the eye, some systemic absorption may occur, leading to side effects like metabolic acidosis (rare). It should be used cautiously in patients with a history of diabetes, kidney disease, or respiratory problems.

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General Medicine

Cortican 100 Injection is a corticosteroid medication containing hydrocortisone, primarily used to treat various inflammatory and allergic conditions. It is administered under medical supervision and is not intended for self-administration. ________________________________________ 🩺 Primary Uses Cortican 100 Injection is employed in the management of: • Severe allergic reactions: Including anaphylaxis and status asthmaticus (severe asthma attacks). • Autoimmune disorders: Such as systemic lupus erythematosus (SLE) and Stevens-Johnson syndrome. • Inflammatory conditions: Including ulcerative colitis, Crohn’s disease, and rheumatoid arthritis. • Joint and tendon inflammations: Conditions like tennis elbow and bursitis. • Adrenal insufficiency: As a replacement therapy for cortisol in conditions like Addison’s disease. • Severe infections or trauma: To manage shock and inflammation resulting from infections or injuries. ________________________________________ ⚙️ Mechanism of Action Hydrocortisone, the active ingredient in Cortican 100, functions by: • Inhibiting the release of substances that cause inflammation, redness, and swelling. • Suppressing the immune system to reduce autoimmune reactions. • Replacing cortisol in the body when adrenal glands do not produce sufficient amounts. ________________________________________ ⚠️ Administration & Safety • Cortican 100 Injection should be administered by a healthcare professional. • It is typically given via intramuscular (IM), intravenous (IV), or intra-articular (joint) injection. • Patients should not self-administer this medication. • Before receiving this injection, inform your doctor if you have any infections, are pregnant or breastfeeding, or have been recently vaccinated. ________________________________________ ⚠️ Side Effects Common side effects may include: • Acne and increased hair growth. • Weight gain and fluid retention. • Dizziness, nausea, and indigestion. • Mood changes, including depression

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General Medicine

Clocivir 500 Injection is an intravenous formulation containing Acyclovir 500 mg, manufactured by American Remedies. It is primarily used to treat severe viral infections caused by herpes viruses. ________________________________________ 🩺 Uses of Clocivir 500 Injection Clocivir 500 Injection is indicated for: • Herpes Simplex Infections in Immunocompromised Patients: Including severe primary or non-primary genital herpes. • Herpes Simplex Encephalitis: A serious brain infection caused by the herpes simplex virus. • Neonatal Herpes Simplex Virus Infection: In newborns. • Varicella-Zoster Infections in Immunocompromised Patients: Such as severe cases of chickenpox or shingles. • Severe Herpes Zoster (Shingles): In immunocompetent patients with very severe acute local or systemic manifestations. ________________________________________ 💊 Mechanism of Action Acyclovir, the active ingredient in Clocivir, is a synthetic purine nucleoside analogue. It exerts its antiviral effects by inhibiting viral DNA synthesis, thereby preventing the replication of herpes viruses. Acyclovir is converted to its active form, Acyclovir Triphosphate, within infected cells, which then interferes with viral DNA polymerase. ________________________________________ ⚠️ Precautions • Administration: Clocivir 500 Injection should be administered by a healthcare professional through slow intravenous infusion over a 1-hour period to minimize the risk of kidney damage. • Hydration: Adequate hydration is essential during treatment to prevent dehydration and kidney damage. • Kidney Function: Use with caution in patients with pre-existing kidney conditions. • Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

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Antiparasitic Medicines

Albendazole and Ivermectin are antiparasitic medications that are often combined in a single tablet to treat a wide range of parasitic infections in the body. 🧬 Combined Uses of Albendazole + Ivermectin Tablet: This combination is commonly used to treat: 🔹 Intestinal Worms: Roundworms (Ascaris) Pinworms (Enterobius) Hookworms (Ancylostoma, Necator) Whipworms (Trichuris) 🔹 Tissue and Systemic Parasitic Infections: Neurocysticercosis (Albendazole is key for brain cysts caused by pork tapeworm) Strongyloidiasis Cutaneous larva migrans (creeping skin eruption from hookworm larvae) Filariasis (Ivermectin especially) 🔹 Scabies & Lice (Ivermectin): Though more commonly treated with topical forms, oral ivermectin is sometimes used for severe or resistant cases.

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Anti Cancer Medicine

6-MP (6-Mercaptopurine) tablets are a prescription medication primarily used to treat certain types of cancers and autoimmune conditions by suppressing abnormal cell growth and activity. 💊 Primary Uses of 6-MP Tablets: ✅ 1. Acute Lymphoblastic Leukemia (ALL) Main use: Maintenance therapy after initial treatment. Function: Prevents cancer cells from growing and dividing. Often used in combination with other chemotherapy drugs. ✅ 2. Crohn’s Disease and Ulcerative Colitis (off-label) Used to suppress the immune system and reduce inflammation in the intestines. Helps in maintaining remission in chronic inflammatory bowel diseases. ✅ 3. Autoimmune Disorders (off-label) Occasionally used for diseases like systemic lupus erythematosus (SLE) or autoimmune hepatitis to control immune response. ⚙️ How It Works: 6-MP is an antimetabolite, which means it interferes with the normal metabolism of cells, especially fast-dividing ones like cancer or immune cells. It alters DNA and RNA synthesis, inhibiting cell replication. 📋 Important Notes: Requires regular blood tests to monitor liver function and white blood cell count. Dosage is highly individualized, based on body weight, condition, and blood work. Thiopurine methyltransferase (TPMT) enzyme activity may be tested before starting, as it affects how the body processes 6-MP. ⚠️ Possible Side Effects: Bone marrow suppression (low blood cells) Liver toxicity Nausea or vomiting Increased risk of infections Loss of appetite ❗ Precautions: Avoid alcohol and certain medications like allopurinol (unless adjusted by your doctor). Not safe during pregnancy unless absolutely necessary. Patients should report fever, fatigue, or unusual bruising/bleeding right away.

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