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HIV/AIDS

INTRODUCTION ABALAM 600/300 is a combination of Abacavir and Lamivudine which belongs to the group of medicines called Anti-viral agents. It is used in the management of HIV infection in adults, adolescents and in children (weighing above 25 kgs). HIV (human immunodeficiency virus) infection is a viral infection that damages our immune system and weakens our body’s ability to fight against various infections. Both abacavir and lamivudine are nucleoside reverse transcriptase inhibitors. They work by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. This prevents further multiplication of viral cells within the body. Also, they can improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. ABALAM 600/300 cannot not manage HIV infection completely. It can reduce only the number of viral cells present in the body and maintains them at a lower level. During management with ABALAM 600/300 your doctor will closely monitor your body weight, blood cholesterol levels and blood sugar levels to reduce the risk of unwanted side effects. Do not take ABALAM 600/300 if you are allergic to abacavir or lamivudine. Before taking ABALAM 600/300 inform your doctor if you have diabetes or any liver (hepatitis C or B infection), kidney or heart problems. If you are already taking ABALAM 600/300 to manage hepatitis B or C infection, do not stop taking it without consulting your doctor. Even if you take ABALAM 600/300, it is important for you to follow certain measures to prevent the spread of infections to the other people (such as avoid having unprotected sexual intercourse or sharing needles or personal items like toothbrush, razors etc with other people). ABALAM 600/300 is not recommended for use in pregnant or breastfeeding women. The most common side effects of taking ABALAM 600/300 are difficulty in sleeping, increased signs of infections, nausea, stomach pain, headache, or dizziness. Consult your doctor if any of these side effects worsens. Also inform your doctor immediately if you experience severe fever with extreme tiredness, sudden changes in body weight or severe stomach pain along with dark urine after taking ABALAM 600/300. USES OF ABALAM 600/300 Manages HIV infection in adults, adolescents and in children (weighing above 25 kgs) HOW ABALAM 600/300 WORKS ABALAM 600/300 is an anti-retroviral medicine. It controls the multiplication of viral cell within the body, by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. It can also improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. DIRECTIONS FOR USE Take ABALAM 600/300 as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. ABALAM 600/300 can be taken with or without meals. Your doctor will decide the correct dose and for how long ABALAM 600/300 must be taken depending upon your age, body weight and severity of the infection. Do not stop taking ABALAM 600/300 without consulting your doctor as it may reduce its effectiveness. SIDE EFFECTS OF ABALAM 600/300 COMMON difficulty in sleeping feeling depressed headache, tiredness, dizziness nausea, diarrhoea fever, skin rash stomach pain loss of appetite irritated or runny nose hair loss UNCOMMON decrease in RBC, WBC, and platelets RARE Stop taking ABALAM 600/300 and contact your doctor immediately if you experience any of the following side effects: signs of allergic reactions (such as skin rash, fever, accompanied with sore throat, cough, nausea, vomiting, stomach pain, diarrhea, tiredness, joint pain, muscle pain, swelling of the neck, difficulty in breathing, mouth ulcers, occasional headaches, inflammation of the eye, low blood pressure, sense of tingling or numbness of hands or feet) pure red cell aplasia (failure of bone marrow to produce new red blood cells) signs of infections (such as fever, headache, stomach-ache, breathing difficulty) signs of auto-immune disorders (such as rapid or irregular heartbeat, tremor, hyperactivity, general weakness) signs of osteonecrosis (death of bone cells causing joint stiffness, pain in the hip, knee or shoulder and difficulty in moving) signs of liver problems (such as yellowing of the skin and whites of the eye, dark urine, light-coloured stools, loss of appetite, nausea, pain, tenderness on the right side of stomach) heart attack changes in body fat (such as increase fat in the shoulder and neck (buffalo hump), breast, and in the middle body or fat loss from the legs, arms, or face)

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Eye Care

Timipar (Timolol Maleate 0.5%) Ophthalmic Solution is a prescription eye drop used to manage elevated intraocular pressure (IOP) in conditions such as open-angle glaucoma and ocular hypertension. By reducing the production of fluid within the eye, it helps lower IOP, thereby reducing the risk of optic nerve damage and potential vision loss. ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common form of glaucoma where the drainage angle in the eye remains open, but the trabecular meshwork is partially blocked, leading to increased IOP. • Ocular Hypertension: A condition characterized by higher-than-normal IOP without any signs of glaucoma damage. ________________________________________ 💊 Dosage and Administration • Typical Dosage: Instill one drop of the 0.5% solution into the affected eye(s) twice daily. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. o After instilling the drop, gently press the corner of your eye (near the nose) for 1–2 minutes to prevent the medication from draining out. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Bronchial asthma or a history of bronchial asthma. o Severe chronic obstructive pulmonary disease (COPD). o Sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock. • Cautions: o Use with caution in patients with a history of heart disease, diabetes, or thyroid disorders, as beta-blockers can mask symptoms of hypoglycemia and hyperthyroidism. o Monitor for potential additive effects when used with other systemic beta-blockers. ________________________________________ 🧪 Mechanism of Action Timolol is a non-selective beta-adrenergic antagonist (beta-blocker) that reduces aqueous humor production in the eye, leading to a decrease in IOP. Its onset of action is typically within 20 minutes, with effects lasting up to 24 hours.

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Eye Care

Timipar (Timolol Maleate 0.25%) eye drops are a prescription medication primarily used to manage elevated intraocular pressure (IOP) associated with conditions like open-angle glaucoma and ocular hypertension. By reducing the production of aqueous humor, the fluid inside the eye, Timolol helps lower IOP, thereby reducing the risk of optic nerve damage and potential vision loss . ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common type of glaucoma where the drainage angle in the eye remains open, but the trabecular meshwork is partially blocked, leading to increased IOP. • Ocular Hypertension: A condition characterized by higher-than-normal IOP without any signs of glaucoma damage. ________________________________________ 💊 Dosage and Administration • Typical Dosage: Instill one drop of the 0.25% solution into the affected eye(s) once or twice daily, as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them . ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Bronchial asthma or a history of bronchial asthma. o Severe chronic obstructive pulmonary disease (COPD). • Sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock . • Cautions: o Use with caution in patients with a history of heart disease, diabetes, or thyroid disorders, as beta-blockers can mask symptoms of hypoglycemia and hyperthyroidism. o Monitor for potential additive effects when used with other systemic beta-blockers . ________________________________________ 🧪 Mechanism of Action Timolol is a non-selective beta-adrenergic antagonist (beta-blocker) that reduces aqueous humor production in the eye, leading to a decrease in IOP. Its onset of action is typically within 20 minutes, with effects lasting up to 24 hours .

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Kidney Disease Medicine

MYCOPHEN 500 MG TABLET belongs to a group of medicines called immunosuppressants. It is used with other medicines to prevent your body from rejecting an organ (such as a kidney, heart, or liver) after a transplant. It works by suppressing your body’s immune system so that it does not attack the new organ. The amount of MYCOPHEN 500 MG TABLET you take and how often you take it depends on the type of transplant you have. Follow your doctor’s instructions on this. Take it on an empty stomach, at least 1 hour before or 2 hours after a meal, unless your doctor suggest otherwise. Swallow it as a whole, do not crush, chew, or break it. Take the medicine regularly to get maximum benefit and keep taking it even when you feel well. The treatment will continue for as long as you need it to prevent rejection. The most common side effects of this medicine include nausea, vomiting, diarrhea, stomach pain, headache, high blood pressure, infections (viral, fungal, bacterial), and changes in the number of white blood cells amongst others. You may catch more infections than usual as medicine suppresses the immune system. There is also an increased risk of developing some cancers for this reason. To reduce your risk of skin cancer, limit your exposure to the sun and use sunscreen. There is a long list of potential side effects of this medicine. You should ask your doctor about them and what signs to look out for because some of them can be serious and need urgent medical attention.

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Heart Disorder

Duron Injection Salt: Amiodarone (150mg) Description Duron 150mg Injection is used to treat various types of serious irregular heartbeat (arrhythmia) such as fibrillation and tachycardia (increased heart rate). It is an anti-arrhythmic type of medicine which rapidly restores your heart to a steady and regular rhythm. Duron 150mg Injection is used to treat various types of serious irregular heartbeat (arrhythmia) such as fibrillation and tachycardia (increased heart rate). It is an anti-arrhythmic type of medicine which rapidly restores your heart to a steady and regular rhythm. Duron 150mg Injection is given by a slow drip (infusion) into a vein under the supervision of a doctor. Continuous monitoring of blood pressure and heart rate may be needed while this medicine is administered. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of the injection. If you stop taking this medicine, you may get dangerous uneven heartbeats, which can be life-threatening. The most common side effects of this medicine include decreased blood pressure (hypotension), decreased heart rate (bradycardia), blurred vision, and application site reaction(pain, itching, and skin redness). This medicine can also cause problems with your liver, lungs, nerves, and thyroid gland. Ask your doctor what signs to look out for and report any symptoms you have. This medicine takes a long time to get cleared from the body. You may continue to have side effects after you stop using it. Ask your doctor about ways to prevent or reduce them Benefits 1. In Arrhythmia: Duron 150mg Injection belongs to a group of medicines called anti-arrhythmics. It works by blocking abnormal electrical signals in the heart. This helps control the uneven beating of your heart and helps it to beat normally. It is normally only given by injection in a hospital when a fast response is needed or when tablets have not worked or cannot be given. This medicine thus prevents serious health problems that can sometimes be fatal and reduces your risk of death. Side Effects Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Common side effects of Duron: - Decreased blood pressure - Slow heart rate - Blurred vision - Application site reactions (burning, irritation, itching and redness)

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Anti Cancer Medicine

Xtane Tablet is an aromatase inhibitor. It is used in the treatment of breast cancer in women who have gone through menopause. It works by adjusting the level of estrogen and helps in slowing down the growth of cancer cells. Xtane Tablet is also used in combination with medication in early cancer to prevent the risk of coming back. It should be taken with food, but take it at the same time every day to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a drink of water. You should take this medicine for as long as it is prescribed for you. The most common side effects of the medicine include insomnia (difficulty sleeping), headache, nausea, increased appetite, and joint pain If these bother you, or appear serious, let your doctor know. There may be ways of reducing or preventing them.

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Eye Care

DEXAPAR Dexamethasone Eye Drops contain Dexamethasone, a potent corticosteroid that helps to reduce inflammation in the eyes. These eye drops are typically used to manage a variety of eye conditions involving inflammation. Here’s a breakdown of the primary uses: 🔹 Primary Uses Treatment of Inflammatory Eye Conditions Dexamethasone is commonly used to treat eye conditions where inflammation is present, such as: Uveitis (inflammation of the uvea, which is part of the eye) Iritis (inflammation of the iris) Conjunctivitis (inflammation of the conjunctiva) Keratitis (inflammation of the cornea) Post-Surgical Inflammation Used after eye surgeries, such as cataract surgery, to control post-operative inflammation and prevent discomfort. Allergic Conjunctivitis May be used for severe allergic reactions causing inflammation in the eye (though often replaced by non-steroidal anti-inflammatory drugs or other treatments). 🔹 How It Works Dexamethasone is a corticosteroid that works by suppressing the immune system to decrease inflammation. It inhibits the release of substances in the body that cause inflammation, such as prostaglandins and cytokines. ⚠️ Common Side Effects Eye irritation or stinging upon application Increased intraocular pressure (which can lead to glaucoma with long-term use) Blurred vision (temporary) Cataract formation (with prolonged use) Eye infections: Prolonged use may increase the risk of developing eye infections. 🔹 Usage Tips Dosage: Typically, 1–2 drops in the affected eye(s), 2 to 4 times a day, depending on the severity of inflammation. Application: Wash your hands before using the eye drops. Tilt your head back and pull down your lower eyelid to form a pocket. Drop the medication into the pocket and close your eye gently. Blink to spread the medication evenly. If using multiple eye medications, wait about 5 minutes between applying each. Contact Lenses: Remove contact lenses before applying the drops and wait 15 minutes before reinserting them. 🔹 Precautions Glaucoma and Cataracts: Prolonged use of Dexamethasone can increase the risk of glaucoma and cataracts, especially in people with a history of these conditions. Infections: Dexamethasone may mask signs of infection. Be cautious if you have an active eye infection. Pregnancy and Breastfeeding: Consult your doctor if you are pregnant or breastfeeding, as corticosteroids may not be suitable in these situations. Long-Term Use: Prolonged or repeated use of corticosteroid eye drops requires careful monitoring by an eye care professional. 🔹 Long-Term Use Dexamethasone Eye Drops are generally not recommended for long-term use unless prescribed by a doctor because of the risk of increasing intraocular pressure, glaucoma, and other complications like cataract formation.

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Anti Cancer Medicine

Degapride 120mg Injection is used in the treatment of advanced prostate cancer. It works by lowering the amount of testosterone produced in the body and restricts the growth of a cancer cell. Degapride 120mg Injection is given as an injection under the skin only under the supervision of a doctor. Do not try to self inject the medicine as it might enhance the chances of an accident or get injected into the veins. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. The most common side effects of this medicine include Injection site reactions (pain, swelling, redness), weight gain, hot flashes, increased liver enzyme, and low sexual desire. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. If you notice dizziness or trouble sleeping, then better to avoid driving or machinery work.

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HIV/AIDS

Salt: Emtricitabine (200mg) + Tenofovir disoproxil fumarate (300mg) + Efavirenz (600mg) Description Viraday Tablets contain two active substances, Emtricitabine and Tenofovir disoproxil fumarate. These medications are a part of the standard combination therapy for HIV, known as antiretroviral therapy (ART). It is a combination drug regimen that is commonly used for the effective treatment of HIV-1 infection. When used correctly and consistently, Viraday tablets have demonstrated high efficacy in HIV treatment and prevention. Benefits Viraday Tablet prevents the HIV virus from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life. It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines. However, taking this medicine will not prevent you from passing HIV to other people. Side Effects Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Viraday Nausea Diarrhea Rash Decreased white blood cell count (neutrophils) Vomiting Abdominal pain Allergic reaction Fatigue Increased lipase in the blood Headache Insomnia (difficulty in sleeping) Depression Dizziness Abnormal dreams Nasopharyngitis (inflammation of the throat and nasal passages) Upper respiratory tract infection Anxiety Sinus inflammation

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