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General Medicine

Nezolid 600 Injection is a brand of Linezolid Injection 600 mg/300 mL, manufactured by American Remedies. Linezolid is an antibiotic belonging to the oxazolidinone class, effective against various serious bacterial infections. ________________________________________ ✅ Primary Uses Nezolid 600 Injection is indicated for the treatment of: • Nosocomial Pneumonia: Hospital-acquired pneumonia caused by susceptible strains of bacteria. • Community-Acquired Pneumonia (CAP): Pneumonia acquired outside of healthcare settings. • Complicated Skin and Skin Structure Infections (cSSSIs): Infections involving deeper layers of the skin and underlying tissues. • Vancomycin-Resistant Enterococcus faecium (VRE) Infections: Including cases with concurrent bacteremia. These infections are typically caused by Gram-positive bacteria, including multidrug-resistant strains. ________________________________________ ⚙️ Mechanism of Action Linezolid works by inhibiting bacterial protein synthesis. It binds to the bacterial ribosome, preventing the formation of the initiation complex necessary for protein production, thereby halting bacterial growth. This bacteriostatic action is particularly effective against Gram-positive organisms. ________________________________________ ⚠️ Precautions • Drug Interactions: Avoid concurrent use with monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), and certain other medications due to the risk of serotonin syndrome. • Pre-existing Conditions: Use with caution in patients with a history of seizures, diabetes mellitus, liver cirrhosis, or renal impairment. • Dietary Restrictions: Limit intake of foods high in tyramine (e.g., aged cheeses, cured meats, soy products) to reduce the risk of hypertensive reactions. • Pregnancy and Lactation: Consult a healthcare provider before use during pregnancy or breastfeeding.

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Eye Care

DEXAPAR Dexamethasone Eye Drops contain Dexamethasone, a potent corticosteroid that helps to reduce inflammation in the eyes. These eye drops are typically used to manage a variety of eye conditions involving inflammation. Here’s a breakdown of the primary uses: 🔹 Primary Uses Treatment of Inflammatory Eye Conditions Dexamethasone is commonly used to treat eye conditions where inflammation is present, such as: Uveitis (inflammation of the uvea, which is part of the eye) Iritis (inflammation of the iris) Conjunctivitis (inflammation of the conjunctiva) Keratitis (inflammation of the cornea) Post-Surgical Inflammation Used after eye surgeries, such as cataract surgery, to control post-operative inflammation and prevent discomfort. Allergic Conjunctivitis May be used for severe allergic reactions causing inflammation in the eye (though often replaced by non-steroidal anti-inflammatory drugs or other treatments). 🔹 How It Works Dexamethasone is a corticosteroid that works by suppressing the immune system to decrease inflammation. It inhibits the release of substances in the body that cause inflammation, such as prostaglandins and cytokines. ⚠️ Common Side Effects Eye irritation or stinging upon application Increased intraocular pressure (which can lead to glaucoma with long-term use) Blurred vision (temporary) Cataract formation (with prolonged use) Eye infections: Prolonged use may increase the risk of developing eye infections. 🔹 Usage Tips Dosage: Typically, 1–2 drops in the affected eye(s), 2 to 4 times a day, depending on the severity of inflammation. Application: Wash your hands before using the eye drops. Tilt your head back and pull down your lower eyelid to form a pocket. Drop the medication into the pocket and close your eye gently. Blink to spread the medication evenly. If using multiple eye medications, wait about 5 minutes between applying each. Contact Lenses: Remove contact lenses before applying the drops and wait 15 minutes before reinserting them. 🔹 Precautions Glaucoma and Cataracts: Prolonged use of Dexamethasone can increase the risk of glaucoma and cataracts, especially in people with a history of these conditions. Infections: Dexamethasone may mask signs of infection. Be cautious if you have an active eye infection. Pregnancy and Breastfeeding: Consult your doctor if you are pregnant or breastfeeding, as corticosteroids may not be suitable in these situations. Long-Term Use: Prolonged or repeated use of corticosteroid eye drops requires careful monitoring by an eye care professional. 🔹 Long-Term Use Dexamethasone Eye Drops are generally not recommended for long-term use unless prescribed by a doctor because of the risk of increasing intraocular pressure, glaucoma, and other complications like cataract formation.

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Eye Care

Cyclopentolate Hydrochloride & Dexamethasone Ophthalmic Solution USP (Cyclopan-D) is a combination eye drop used for specific eye conditions involving both inflammation and pupil dilation. Here's a breakdown of its uses: 🔹 Primary Uses Treatment of Uveitis (Inflammation of the Uvea) Cyclopentolate dilates the pupil, helping to alleviate pain associated with inflammation in the eye. Dexamethasone, a corticosteroid, reduces inflammation. Post-Operative Inflammation and Pain Relief After eye surgeries (e.g., cataract surgery), this combination helps manage inflammation and promotes healing. Pupil Dilation for Diagnostic Purposes Used before certain eye exams or surgeries to dilate the pupil for better visibility and assessment of the eye's interior. 🔹 How It Works Cyclopentolate Hydrochloride: A muscarinic antagonist that causes pupil dilation (mydriasis) by blocking the action of acetylcholine on the muscles in the iris, which normally constrict the pupil. Dexamethasone: A potent corticosteroid that reduces inflammation by suppressing the immune response and inhibiting the production of inflammatory chemicals. Together, they reduce pain, control inflammation, and help improve vision in certain conditions by dilating the pupil and promoting healing. ⚠️ Common Side Effects Temporary blurred vision (due to pupil dilation) Stinging or burning after application Increased intraocular pressure (with prolonged use of dexamethasone) Sensitivity to light (from dilated pupil) Dryness or irritation in the eye 🔹 Usage Instructions Frequency: Follow your doctor's prescribed schedule, typically 1–2 drops in the affected eye(s) up to 4 times a day (especially for inflammation). For pupil dilation, it's usually a single application before the procedure or exam. Application Tips: Wash your hands before use. Tilt your head back and gently pull down the lower eyelid to form a pocket. Drop the medication into the pocket without touching the dropper to the eye. Close your eye gently and blink to spread the solution. If you have multiple eye drops to use, wait at least 5–10 minutes between applications. Contact Lenses: Remove contact lenses before using this drop and wait at least 15 minutes before reinserting. 🔹 Precautions Long-term Use: Dexamethasone can increase intraocular pressure and lead to glaucoma or cataract formation with prolonged use, so it should be used cautiously. Allergic Reactions: Inform your doctor if you're allergic to steroids, anticholinergic drugs, or any ingredients in this eye drop. Pregnancy and Breastfeeding: Consult with a healthcare provider before use if you are pregnant or breastfeeding.

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Anti Cancer Medicine

FLURACIL 250MG INJECTION contains Fluorouracil, which belongs to a group of medicines called Nucleoside metabolic inhibitors. FLURACIL 250MG INJECTION is used to manage cancer involving the breast, oesophagus, stomach, colon, rectum, pancreas, prostate, ovary, bladder, and head and neck cancer. FLURACIL 250MG INJECTION should not be used in patients with serious infections (for example, Herpes zoster or chickenpox), non-malignant tumours, poor nutrition, weakened immunity due to long illness, damaged bone marrow due to other antineoplastics or radiotherapy, severe liver disease, or homozygotic or complete deficiency of dihydropyrimidine dehydrogenase (DPD) enzyme. FLURACIL 250MG INJECTION should be used with caution in patients with decreased blood cells, oral ulcers, fever or haemorrhage at any site or weakness (due to decreased blood cells), kidney or liver problems like jaundice (yellowing of the skin) or heart problems like chest pain, reduced activity or deficiency of the enzyme DPD (dihydropyrimidine dehydrogenase), had high-dose radiation to pelvic, spine, ribs, metastatic tumours with involvement of bone marrow, severe bone marrow suppression include neutropenia, thrombocytopenia, and anaemia, viral, bacterial, fungal and/or parasitic infections, encephalopathy, gastrointestinal side effects like stomatitis, diarrhoea, bleeding from the G.I. tract or haemorrhage at any site, family history of partial or complete deficiency of the enzyme dihydropyrimidine dehydrogenase (DPD), had recent major surgery.

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HIV/AIDS

Marketer Steadfast Medishield Pvt Ltd SALT COMPOSITION Valganciclovir (450mg) Storage Store below 30°C Uses of Valstead Tablet Treatment of Cytomegalovirus Infection Herpes labialis Genital herpes infection Chickenpox Herpes Simplex Virus Infections Eye infections by Herpes simplex virus Chronic hepatitis C virus (HCV) infection Product introduction Valstead 450mg Tablet is used to treat cytomegalovirus (CMV) infection of the retina (retinitis) in adult patients with acquired immunodeficiency syndrome (AIDS). It is also used for the prevention of CMV infection in patients who have received an organ transplant from a CMV-infected donor. Valstead 450mg Tablet should be taken in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. It should be taken with food. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. You should drink plenty of water while on treatment with this medicine as it helps to prevent dehydration and kidney damage. It may lead to a few common side effects like fever, diarrhea, vomiting, anemia, low white blood cell, and low platelet level. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding. Benefits of Valstead Tablet In Treatment of Cytomegalovirus Infection Cytomegalovirus infection is a common virus infection which may have no symptoms at all or may have symptoms like fever and fatigue. Severe infection may show symptoms involving the eyes, brain, or other internal organs. This virus is spread through sexual and nonsexual contact with body secretions in people who are immunocompromised or those who have undergone any transplant. Valstead 450mg Tablet helps to prevent multiplication of the infection causing virus and treats the infection. Keep taking it in the dose and duration prescribed by the doctor to get maximum benefit. Side effects of Valstead Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Valstead Diarrhea Fever Vomiting Anemia (low number of red blood cells) Decreased white blood cell count Low blood platelets Insomnia (difficulty in sleeping) Tremors How to use Valstead Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Valstead 450mg Tablet is to be taken with food. How Valstead Tablet works Valstead 450mg Tablet is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

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Anti Cancer Medicine

Marketer BDR Pharmaceuticals Internationals Pvt SALT COMPOSITION Gimeracil (5.8mg) + Oteracil (15.8mg) + Tegafur (20mg) Uses of Furmecil Capsule Treatment of Stomach cancer Product introduction Furmecil Capsule is a combination medicine used in the treatment of stomach cancer. It can be used alone or in combination with some medicines as part of combination chemotherapy. It works by interfering with the growth of cancer cells, which are eventually destroyed. Furmecil Capsule should be taken with water at least 1 hour before or 1 hour after a meal. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include bone marrow suppression, acute renal failure, diarrhea, dehydration, electrolyte disturbance, and lacrimal disorders. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Before taking this medicine, inform your doctor if you have medical conditions involving blood, kidney, and liver or if you are suffering from any breathing disorder. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Benefits of Furmecil Capsule In Treatment of Stomach cancer Stomach cancer also known as gastric cancer, may occur in the inner lining (called mucosa) of the stomach or in the walls of the stomach. These are of various kinds depending on the origin, affected area and severity of the cancer. Furmecil Capsule helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit. Side effects of Furmecil Capsule Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Furmecil Bone marrow suppression Acute renal failure Diarrhea Dehydration Electrolyte imbalance Lacrimation (flow of tears) How to use Furmecil Capsule Take this medicine in the dose and duration as advised by your doctor. Furmecil Capsule is to be taken empty stomach. How Furmecil Capsule works Furmecil Capsule is a combination of anticancer medications. Tegafur gets converted to its active form known as 5-fluorouracil (5-FU) that inhibits the synthesis and function of genetic material DNA and RNA and prevents the growth of cancer cells. Gimeracil prevents the breakdown of 5-FU, which helps maintain high concentrations of 5-FU against cancer cells. Oteracil suppresses 5-FU’s gastrointestinal toxicity.

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