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Items tagged with 'severe kidney impairment'

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Hepatitis Medicine

Sovihep 400mg Tablet contains the active component Sofosbuvir. It is a direct-acting antiviral medication used to treat hepatitis C virus (HCV) infection. This medication is often combined with other antiviral drugs to form a regimen that can effectively eliminate HCV from the body. Sovihep 400mg Tablet has significantly shortened the duration of HCV treatment compared to older therapies. It is effective against multiple genotypes of the hepatitis C virus. This broad-spectrum activity makes it a versatile treatment option that can be used for a wide range of patients infected with different HCV genotypes. Patients have generally well-tolerated with this medication, with few serious side effects reported. Sovihep 400mg Tablet should not be used in individuals with known hypersensitivity or allergic reactions to it or its components. This medication is primarily eliminated through the kidneys. Therefore, individuals with severe renal impairment may require dosage adjustments. It is not approved for use in children under the age of 18.

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Hepatitis Medicine

Viroclear 400mg Tablet contains the active component as Sofosbuvir. It is a direct-acting antiviral medication used to treat hepatitis C virus (HCV) infection. This medication is often combined with other antiviral drugs to form a regimen that can effectively eliminate HCV from the body. Viroclear 400mg Tablet has significantly shortened the duration of HCV treatment compared to older therapies. It is effective against multiple genotypes of the hepatitis C virus. This broad-spectrum activity makes it a versatile treatment option that can be used for a wide range of patients infected with different HCV genotypes. Patients have generally well-tolerated with this medication, with few serious side effects reported. Viroclear 400mg Tablet should not be used in individuals with known hypersensitivity or allergic reactions to it or its components. This medication is primarily eliminated through the kidneys. Therefore, individuals with severe renal impairment may require dosage adjustments. It is not approved for use in children under the age of 18.

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Hepatitis Medicine

Sofovir 400mg Tablet contains the active component as Sofosbuvir. It is a direct-acting antiviral medication used to treat hepatitis C virus (HCV) infection. This medication is often combined with other antiviral drugs to form a regimen that can effectively eliminate HCV from the body. Sofovir 400mg Tablet has significantly shortened the duration of HCV treatment compared to older therapies. It is effective against multiple genotypes of the hepatitis C virus. This broad-spectrum activity makes it a versatile treatment option that can be used for a wide range of patients infected with different HCV genotypes. Patients have generally well-tolerated with this medication, with few serious side effects reported. Sofovir 400mg Tablet should not be used in individuals with known hypersensitivity or allergic reactions to it or its components. This medication is primarily eliminated through the kidneys. Therefore, individuals with severe renal impairment may require dosage adjustments. It is not approved for use in children under the age of 18.

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Anti Cancer Medicine

INTAXEL 260MG INJECTION contains Paclitaxel which belongs to a group of anti-cancer medicines called Taxanes. INTAXEL 260MG INJECTION is used to manage ovarian and breast cancer as a first line of therapy and as a second line of management when platinum containing medicines (such as cisplatin) or anthracyclines are insufficient to manage the disease in affected individuals. INTAXEL 260MG INJECTION is also used to manage advanced NSCLC (non-small cell lung cancer) when surgery/radiation therapy is not suitable. The medicine is also indicated for use to manage AIDS-related Kaposi’s sarcoma when other managements (such as anthracyclines) are insufficient to manage the disease in affected individuals. INTAXEL 260MG INJECTION is not recommended for use in patients allergic to paclitaxel and polyoxyethylated castor oil. It is also not recommended for use in patients with few white blood cells count and serious & uncontrolled infection. The medicine is also not used in patients suffering from severe liver disease. Before receiving INTAXEL 260MG INJECTION, inform your doctor if you had previously received radiation to your chest and/or suffering from thrombocytopenia (low platelet count)/acute infections (such as herpes zoster, chickenpox, herpes), kidney problems (such as chronic kidney disease), liver problems (such as mild/moderate hepatic impairment) and/or heart problems (such as severe coronary artery disease, myocardial infarction and arrhythmias).

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Anti Cancer Medicine

INTRODUCTION ABOUT TAXONAB 100MG INJECTION TAXONAB 100MG INJECTION contains Paclitaxel which belongs to a group of anti-cancer medicines called Taxanes. TAXONAB 100MG INJECTION is used to manage ovarian and breast cancer as a first line of therapy and as a second line of management when platinum containing medicines (such as cisplatin) or anthracyclines are insufficient to manage the disease in affected individuals. TAXONAB 100MG INJECTION is also used to manage advanced NSCLC (non-small cell lung cancer) when surgery/radiation therapy is not suitable. The medicine is also indicated for use to manage AIDS-related Kaposi’s sarcoma when other managements (such as anthracyclines) are insufficient to manage the disease in affected individuals. TAXONAB 100MG INJECTION is not recommended for use in patients allergic to paclitaxel and polyoxyethylated castor oil. It is also not recommended for use in patients with few white blood cells count and serious & uncontrolled infection. The medicine is also not used in patients suffering from severe liver disease. Before receiving TAXONAB 100MG INJECTION, inform your doctor if you had previously received radiation to your chest and/or suffering from thrombocytopenia (low platelet count)/acute infections (such as herpes zoster, chickenpox, herpes), kidney problems (such as chronic kidney disease), liver problems (such as mild/moderate hepatic impairment) and/or heart problems (such as severe coronary artery disease, myocardial infarction and arrhythmias). TAXONAB 100MG INJECTION is not recommended for use during pregnancy. Women of child-bearing potential should use effective contraception method while receiving TAXONAB 100MG INJECTION which should be continued for next-6 months after completing the management. The medicine is also not recommended for use in breastfeeding women. TAXONAB 100MG INJECTION is also not recommended for use in children and adolescents (aged below 18 years). The medicine can be used with caution in elderly patients (aged above 65 years) after consulting the doctor. The most common side effects of receiving TAXONAB 100MG INJECTION are minor allergic reactions (such as flushing, rash, itching), shortness of breath, sore throat/mouth ulcers, diarrhea, nausea, vomiting and/or loss of hair. Consult your doctor if any of these symptoms worsen. USES OF TAXONAB 100MG INJECTION Manage ovarian and breast cancer. Manage advanced NSCLC (non-small cell lung cancer) Manage AIDS-related Kaposi’s sarcoma in affected individuals. HOW TAXONAB 100MG INJECTION WORKS TAXONAB 100MG INJECTION works by interfering with the microtubule structures in the cell (substance which aids cancer cells to divide and multiply) thus inhibiting the growth of cancer cells and managing its spread in affected individuals. DIRECTIONS FOR USE TAXONAB 100MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF TAXONAB 100MG INJECTION COMMON minor allergic reactions such as flushing, rash and/or itching infections such as upper respiratory infection, urinary tract infection shortness of breath sore throat/mouth ulcers, sore and red mouth diarrhea, nausea, vomiting loss of hair pain in the muscles, cramps, joints fever, severe chills, headache, dizziness, tiredness, looking pale bleeding, bruising more easily than normal signs of peripheral neuropathy such as numbness, tingling/weakness in arms and legs temporary mild nail change and skin changes reactions at injection sites such as localized swelling, pain and/or redness of the skin. UNCOMMON septic shock (severe drop in blood pressure) due to infections racing heartbeat, rapid beating of the heart, respiratory distress, heart attack, heart block fatigue, sweating, fainting, significant allergic reactions, phlebitis (inflammation of a vein), swelling of the face, lips, mouth, tongue and/or throat back pain, chest pain, pain around hands and feet, chills, abdominal pain. RARE febrile neutropenia (type of fever) due to low white blood cell count associated with fever and increased risk of infection motor neuropathy (disease that affects your body’s motor nerves) pulmonary embolism (blockade of lung artery), lung fibrosis (damaged/scarred lung tissue), interstitial pneumonia (scarring of lung tissue), pleural effusion (build of fluid between lungs and chest) bowel obstruction, bowel perforation, inflammation of colon, inflammation of the pancreas (pancreatitis) skin redness peritonitis (inflammation of abdominal layer) fever, dehydration, weakness anaphylactic reactions (life threatening allergic reaction). HOW TO MANAGE SIDE EFFECTS Diarrhea: Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult your doctor and inform them if the symptom gets worse.

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General Medicine

Colistican 3 Injection is an intravenous formulation containing Colistimethate Sodium 3 Million IU, manufactured by American Remedies. It is primarily used to treat severe infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 3 Injection Colistican 3 Injection is indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bloodstream Infections (Sepsis): Infections caused by resistant bacteria entering the bloodstream. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. • Intra-abdominal Infections: Such as peritonitis. • Cystic Fibrosis: For chronic pulmonary infections due to Pseudomonas aeruginosa in both adults and children. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

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Antibiotic Medicine

Colistican 2 Injection is a brand of Colistimethate Sodium for Injection, manufactured by American Remedies. It is a polymyxin-class antibiotic used to treat serious infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 2 Injection Colistican 2 Injection is primarily indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bacteremia (Bloodstream Infection): Infections caused by resistant bacteria entering the bloodstream. • Lower Respiratory Tract Infections: Including severe cases of pneumonia and bronchitis. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. These infections are typically caused by pathogens such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae, which are resistant to multiple antibiotics. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

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General Medicine

Canrise D3 6L Injection is a high-dose Vitamin D3 (Cholecalciferol) supplement manufactured by American Remedies. It is primarily used to address significant Vitamin D deficiencies and related bone health issues. ________________________________________ 🩺 Uses of Canrise D3 6L Injection • Vitamin D Deficiency: To replenish low levels of Vitamin D, which is essential for calcium absorption and bone health. • Osteoporosis: To improve calcium absorption and bone mineralization, reducing the risk of fractures. • Osteomalacia: To treat softening of the bones due to Vitamin D deficiency. • Adjuvant in Calcium Supplementation: To enhance the effectiveness of calcium supplements in individuals with low Vitamin D levels. ________________________________________ 💊 Mechanism of Action Vitamin D3 aids in the absorption of calcium and phosphate from the intestine, regulates calcium levels in the blood, and supports bone mineralization. It also plays a role in immune function and inflammation reduction. ________________________________________ ⚠️ Precautions • Contraindications: Individuals with hypercalcemia (high calcium levels), hypercalciuria (high calcium in urine), or severe kidney impairment should avoid this injection. • Monitoring: Regular monitoring of calcium and phosphate levels is recommended during treatment. • Administration: Should be administered under medical supervision, typically in a clinical setting.

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Eye Care

Z Brom 5 ml is an ophthalmic solution that relieves postoperative eye pain and inflammation following cataract surgery. Manufactured by Sunways India Pvt Ltd, it contains Bromfenac (0.09% w/v), a Non-Steroidal Anti-Inflammatory Drug (NSAID). This medication works by blocking the release of certain chemical substances responsible for inflammation, thereby reducing pain, swelling, and redness. It is commonly prescribed to enhance post-surgical recovery and improve patient comfort. This medicine is strictly for external use. Before application, wash your hands thoroughly to maintain hygiene and avoid contamination. Tilt your head back, pull down the lower eyelid, and administer the prescribed number of drops while ensuring the dropper tip does not touch your eye or any other surface. If you wear contact lenses, remove them before using Z Brom 5 ml and wait at least 15 minutes before reinserting them. It is essential to use this medication as directed by your doctor. Store below 30°C, tightly close the bottle after each use, and keep it out of reach of children. If you experience persistent irritation or worsening symptoms, seek medical advice promptly. What are the benefits of Z Brom 5 ml Z Brom 5 ml offers several benefits for postoperative eye care: Reduces pain, redness, and swelling after cataract surgery. Provides relief from ocular inflammation. It helps improve post-surgical recovery and comfort. Easy to administer, with quick absorption in the eye. NSAID-based, reducing inflammation without the need for steroids. How to use Z Brom 5 ml Z Brom 5 ml is a prescription medication. Consult your doctor before use. General guidelines include: Instill one drop into the affected eye(s) twice daily. Start using one day before cataract surgery and continue for 14 days post-surgery. Follow your doctor’s instructions for the exact duration and frequency. Strengths and substitutes Z Brom has various strengths and substitutes. Your doctor may adjust your dosage based on your specific condition and response to treatment. At Cheap Medicine Shop, we currently do not have other strengths available. Available substitutes include: Hibrom 0.09% 5 ml $3.93/ 10 eye drops View all substitutes What are the side effects of Z Brom 5 ml Generally safe when taken as prescribed, Z Brom may cause mild side effects, including: Blurred vision Increased sensitivity to light Changes in color vision Decreased vision Eye pain or soreness Teary eyes Headache Severe allergic reactions are rare but require immediate medical attention. Safety Advice Liver problemsLiver disease Patients with liver disease should consult their doctor before using Z Brom. The liver plays a key role in drug metabolism, and any impairment may affect how the medication is processed. While no significant interactions are known, caution is advised to prevent adverse effects. CardiovascularKidney impairment Individuals with kidney impairment should seek medical advice before using Z Brom. The kidneys help filter medications from the body, and impaired function may alter drug elimination. Proper assessment is necessary to ensure the medication is safe and appropriate. PregnancyPregnant and breastfeeding women Consult your doctor. Limited human data suggests minimal risk during breastfeeding. wineAvoid Driving immediately after use due to temporary blurred vision. Alcohol interactions are unknown but should be avoided for safety.

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