Marketer Getwell Pharma (I) Pvt Ltd SALT COMPOSITION Thiotepa (15mg) Storage Store below 30°C Uses of Tepawel Injection Malignant melanoma Hodgkin’s disease Multiple myeloma Brain tumor Blood cancer Breast cancer Non-small cell lung cancer Ovarian cancer Lung cancer Product introduction Tepawel 15mg Injection is used in the treatment of cancers of the brain, breast, lungs, and ovaries. It is used in combination with other cancer medicine during hematopoietic progenitor cell transplantation (HPCT). It may be also used to treat other conditions, as determined by the doctor. Tepawel 15mg Injection is generally given under the supervision of a healthcare professional. Your doctor will decide the dose and duration of the treatment based on the severity of your condition and what you are being treated for. It may take several weeks or months for you to see or feel the benefits but do not stop getting the injection unless your doctor tells you to. The most common side effects of this medicine include decreased white blood count, anemia, low blood platelets, increased liver enzymes, increased bilirubin in the blood, mucosal inflammation, hemorrhage, diarrhea, blood in urine, and rash. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidneys, liver, and heart function during treatment with this medicine. Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Side effects of Tepawel Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Tepawel Decreased white blood cell count (neutrophils) Anemia (low number of red blood cells) Low blood platelets Increased liver enzymes Increased bilirubin in the blood Mucosal inflammation Hemorrhage Rash Diarrhea Blood in urine How to use Tepawel Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Tepawel Injection works Tepawel 15mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Tepawel 15mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Tepawel 15mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Tepawel 15mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Tepawel 15mg Injection may cause side effects which could affect your ability to drive. It is likely that certain adverse events of Tepawel 15mg Injection are dizziness, headache, and blurred vision which could affect your ability to drive. warnings Kidney SAFE IF PRESCRIBED Tepawel 15mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Tepawel 15mg Injection may not be needed in these patients. Please consult your doctor. warnings Liver CAUTION Tepawel 15mg Injection should be used with caution in patients with liver disease. Dose adjustment of Tepawel 15mg Injection may be needed. Please consult your doctor. Regular monitoring of liver function tests may be advised while you are taking this medicine.

Description: Stanozolol is a synthetic anabolic steroid that belongs to the androgen class of medicines. It is also known as Stanorix, which is the brand name for it. Stanozolol is mostly used in hospitals to treat illnesses like angioedema and anemia. Chemical Structure. Stanozolol is a synthetic 17-alkylated androstane steroid and a derivative of 5-dihydrotestosterone (DHT) with a methyl group at the C17 position and a pyrazole ring linked to the A ring of the steroid nucleus. Uses : Treatment of Angioedema: Stanozolol can be used to treat hereditary angioedema, a rare genetic condition that causes swelling in many regions of the body, including the face, extremities, and genitals. It aids in lowering the frequency and intensity of these occurrences. Wasting Syndromes: Stanozolol may be used to treat muscle wasting and weight loss caused by disorders such as HIV/AIDS or other chronic diseases. Anabolic Effects: Stanozolol has anabolic qualities, which means it encourages muscle tissue growth. As a result, it is popular among sportsmen and bodybuilders who want to gain muscle bulk and strength. Androgenic capabilities: It also possesses androgenic capabilities, which can result in the development of secondary sexual traits such as facial hair growth and voice deepening. Side Effects : An allergic reaction (difficulty breathing, throat closure, swelling of the lips, tongue, or cheeks, or hives). Erections that are frequent or persistent, or breast discomfort or enlargement (in male patients). Changes in voice (hoarseness, deepening), hair loss, facial hair growth, clitoral enlargement, or menstruation irregularities (only in female patients).

INTRODUCTION ABOUT ENCORATE CHRONO 500MG TABLET ENCORATE CHRONO 500MG TABLET is a combination of Sodium valproate and Valproic acid, which belong to the group of medicines called Anticonvulsant/Antiepileptic drugs. It is used to manage epilepsy in adults and children. It is also used to manage bipolar disorders. Epilepsy is an abnormal electrical activity in the brain and nervous system. The symptoms may include temporary confusion, muscle stiffness, jerky movements in legs or arms, loss of consciousness, psychological symptoms (such as anxiety or fear), etc. ENCORATE CHRONO 500MG TABLET is not recommended for use in patients with liver problems or with a family history of liver problems, porphyria (a hereditary disease that affects the skin or nervous system), blood coagulation or clotting disorders, pancreatic diseases (inflammation of the pancreas), urea cycle disorder (a genetic disorder) or Alpers-Huttenlocher syndrome (a rare disorder that affects brain, liver & muscles), etc. ENCORATE CHRONO 500MG TABLET should be used with caution in patients with kidney problems or lung diseases (such as chronic obstructive pulmonary disease) and diabetes. ENCORATE CHRONO 500MG TABLET is also not recommended for use in pregnant and breastfeeding women. It should be used with caution in children (below 2 years of age). Consult your doctor before taking the medicine. The common side effects of taking ENCORATE CHRONO 500MG TABLET may include dizziness, headache, sleep disorders, clumsiness/unsteadiness, trembling of hands and arms and nervousness. Consult your doctor if any of the symptoms worsen or persist. USES OF ENCORATE CHRONO 500MG TABLET Manage epilepsy Manage bipolar disorders HOW ENCORATE CHRONO 500MG TABLET WORKS ENCORATE CHRONO 500MG TABLET helps in managing epilepsy, where sodium valproate and valproic acid effectively increases the GABA (a neurotransmitter/chemical messenger) concentration in the central nervous system by reducing its degradation. It also blocks certain ion channels which reduce high-frequency neuronal activity in the brain, thereby reliving seizure activity. DIRECTIONS FOR USE Take ENCORATE CHRONO 500MG TABLET as advised by your physician. Swallow the medicine with a glass of water with or after food. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition. SIDE EFFECTS OF ENCORATE CHRONO 500MG TABLET COMMON headache sleep disorders clumsiness or unsteadiness trembling of hands and arms nervousness changing moods blurred vision ringing in ears deafness dizziness flu abdominal or stomach pain heartburn nausea and vomiting diarrhoea skin rash hair loss or thinning of hair back pain change in menstrual periods lack or loss of strength mental confusion aggression convulsion memory problems becoming unreactive bedwetting signs of liver damage such as skin and eyes that appear yellowish (jaundice), abdominal pain and swelling. signs of inflammation of the pancreas (pancreatitis) such as upper abdominal pain, abdomen tenderness, fever and rapid pulse signs of Fanconi syndrome (a disorder of kidney tubes) such as excessive thirst, urination, vomiting overgrown gum tissue agitation disturbance in attention abnormal behaviour hyperactivity learning disorder UNCOMMON unusual bleeding or bruising abnormal dreams anxiety feeling sad irritability pain in joints cough constipation dry eyes spots before the eyes ear infection ear pain runny nose dental pain bloating muscle pains or stiffness tiredness weight gain or loss learning disorder coma loss of muscle control brittle bones and fractures shortness of breath chest pain blood clotting problems RARE Stop taking ENCORATE CHRONO 500MG TABLET and contact your doctor if you experience any of the following side effects: signs of allergic reactions such as swelling of the face, lips, eyelids, throat and tongue, which may cause difficulty in breathing and swallowing signs of altered levels of ammonia in the blood characterized by vomiting, balance issues and lack of alertness signs of liver problems characterized by nausea, vomiting, tiredness, sleepiness, weakness, stomach pain, yellowing of the skin or whites of the eye signs of inflammation of the pancreas characterized by acute abdominal pain chest pain shortness of breath hallucinations suicidal thoughts psychosis (mental disorder causing disconnection from reality) toxic epidermal necrolysis (life-threatening skin disorder causing widespread skin pain, rashes, blisters, sores and crusting) Steven-Johnson syndrome (a skin disorder characterized by painful rashes and blisters on the skin) anaphylaxis (severe allergic reaction characterized by shortness of breath, fainting or fastened heartbeat) erythema multiforme (a skin condition characterized by raised red rashes on the skin)

Paricar (Pilocarpine Nitrate 4%) Eye Drops are a miotic ophthalmic solution primarily used to manage certain eye conditions by reducing intraocular pressure. ________________________________________ 🔍 Uses 1. Treatment of Glaucoma and Ocular Hypertension Pilocarpine Nitrate 4% is employed to lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It facilitates the drainage of aqueous humor from the eye, thereby reducing IOP and helping prevent vision loss and nerve damage. 2. Management of Acute Angle-Closure Glaucoma In acute angle-closure glaucoma, Pilocarpine Nitrate 4% may be used to constrict the pupil, facilitating the opening of the angle between the iris and cornea, which helps in reducing IOP. 3. Induction of Miosis Pilocarpine Nitrate 4% is utilized to induce miosis (pupil constriction) during certain eye surgeries or to reverse the effects of drugs used to dilate the pupil during eye examinations. ________________________________________ 💧 Dosage and Administration • General Dosage: Instill one drop into the affected eye(s) 1 to 4 times daily, as directed by your healthcare provider. • Application Method: 1. Wash your hands thoroughly before use. 2. Tilt your head back slightly and pull down the lower eyelid to form a pouch. 3. Hold the dropper above the eye and instill the prescribed number of drops. 4. Close the eye gently and apply gentle pressure to the inner corner of the eye for 1 to 2 minutes to prevent the medication from draining away. 5. Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects: o Temporary eye discomfort, such as stinging or burning sensations. o Blurred vision. o Headache. • Visual disturbances. • Serious Side Effects: o Although rare, systemic absorption may lead to increased blood pressure, headache, or dizziness. • Precautions: o Consult your doctor if you are pregnant or breastfeeding, as the safety of Pilocarpine Nitrate 4% during these periods is not well-established. o Use with caution if you have a history of retinal diseases or other eye conditions. o Avoid driving or operating machinery if you experience blurred vision or visual disturbances.

Paricar (Pilocarpine Nitrate 2% Eye Drops) is a miotic ophthalmic solution primarily used to manage certain eye conditions by reducing intraocular pressure. ________________________________________ 🔍 Uses 1. Treatment of Glaucoma and Ocular Hypertension Pilocarpine Nitrate 2% is employed to lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It facilitates the drainage of aqueous humor from the eye, thereby reducing IOP and helping prevent vision loss and nerve damage. 2. Management of Acute Angle-Closure Glaucoma In acute angle-closure glaucoma, Pilocarpine Nitrate 2% may be used to constrict the pupil, facilitating the opening of the angle between the iris and cornea, which helps in reducing IOP. 3. Induction of Miosis Pilocarpine Nitrate 2% is utilized to induce miosis (pupil constriction) during certain eye surgeries or to reverse the effects of drugs used to dilate the pupil during eye examinations. ________________________________________ 💧 Dosage and Administration • General Dosage: Instill one drop into the affected eye(s) 1 to 4 times daily, as directed by your healthcare provider. • Application Method: 1. Wash your hands thoroughly before use. 2. Tilt your head back slightly and pull down the lower eyelid to form a pouch. 3. Hold the dropper above the eye and instill the prescribed number of drops. 4. Close the eye gently and apply gentle pressure to the inner corner of the eye for 1 to 2 minutes to prevent the medication from draining away. 5. Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects: o Temporary eye discomfort, such as stinging or burning sensations. o Blurred vision. o Headache. • Visual disturbances. • Serious Side Effects: o Although rare, systemic absorption may lead to increased blood pressure, headache, or dizziness. • Precautions: o Consult your doctor if you are pregnant or breastfeeding, as the safety of Pilocarpine Nitrate 2% during these periods is not well-established. o Use with caution if you have a history of retinal diseases or other eye conditions. o Avoid driving or operating machinery if you experience blurred vision or visual disturbances.

Procitil Injection is a medication that contains Prochlorperazine, a phenothiazine class drug. It is primarily used to treat: 1. Severe Nausea and Vomiting Procitil is effective in managing nausea and vomiting caused by various conditions, including: • Post-operative recovery • Chemotherapy-induced nausea • Gastrointestinal disorders 2. Psychotic Disorders Prochlorperazine, the active ingredient in Procitil, has antipsychotic properties and is used to manage symptoms of: • Schizophrenia • Delirium • Severe anxiety 3. Vertigo and Dizziness It helps alleviate dizziness and balance issues associated with inner ear problems. 4. Severe Anxiety Procitil can be used in the short-term management of severe anxiety when other treatments are not effective. 5. Hiccups In some cases, Procitil is used to treat persistent and severe hiccups. Administration Procitil Injection is administered intravenously or intramuscularly by a healthcare professional. The dosage and frequency depend on the specific condition being treated and the patient's response to therapy. Side Effects Common side effects may include: • Drowsiness or sedation • Dizziness • Dry mouth • Constipation • Blurry vision • Muscle stiffness or tremors • Serious side effects are rare but can include: • Severe allergic reactions • Neuroleptic malignant syndrome (a life-threatening condition) • Tardive dyskinesia (involuntary movements) If you experience any unusual symptoms, contact your healthcare provider immediately. Precautions Before using Procitil Injection, inform your doctor if you have: • Allergies to prochlorperazine or other phenothiazines • Liver or kidney disease • Heart problems • Seizure disorders • Parkinson's disease • Pregnancy or breastfeeding status

Pipracan 4.5 Injection is a combination antibiotic medication containing Piperacillin (4 g) and Tazobactam (0.5 g). This formulation is used to treat a wide range of serious bacterial infections that may not respond to other antibiotics. ________________________________________ 🔹 Common Uses Pipracan 4.5 Injection is prescribed for: • Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) • Urinary tract infections (UTIs) • Intra-abdominal infections (e.g., peritonitis) • Skin and soft tissue infections, including diabetic foot infections • Gynecological infections, such as uterine infections • Bone and joint infections • Bloodstream infections (bacteremia) It is also used for prophylactic treatment in surgical procedures to prevent infections. ________________________________________ 🔹 How It Works • Piperacillin is a broad-spectrum penicillin antibiotic that inhibits bacterial cell wall synthesis, leading to bacterial cell death. • Tazobactam is a beta-lactamase inhibitor that protects piperacillin from degradation by beta-lactamase enzymes produced by certain bacteria, thereby enhancing its efficacy. This combination allows Pipracan 4.5 to target a wide array of bacteria, including those resistant to other antibiotics. ________________________________________ 🔹 Administration Pipracan 4.5 Injection is administered intravenously by a healthcare professional. The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient's medical condition. Self-administration is not recommended. ________________________________________ 🔹 Side Effects Common side effects may include: • Nausea or vomiting • Diarrhea • Rash or itching • Pain, redness, or swelling at the injection site Serious side effects are rare but can include allergic reactions, liver enzyme abnormalities, or blood disorders. Seek immediate medical attention if you experience symptoms like difficulty breathing, swelling of the face or throat, or unusual bruising or bleeding. ________________________________________ 🔹 Precautions Before using Pipracan 4.5 Injection, inform your doctor if you have: Allergies to penicillins or beta-lactam antibiotics • Kidney or liver disease • A history of gastrointestinal diseases, such as colitis • Bleeding disorders • Undergoing dialysisUse during pregnancy and breastfeeding should be discussed with your healthcare provider. The medication should only be used if the potential benefits justify the potential risks.

Mucanix Injection is a brand of Acetylcysteine Injection, manufactured by American Remedies. Acetylcysteine is a mucolytic agent that helps in thinning and loosening mucus in the airways, making it easier to cough up and clear the airways. ________________________________________ ✅ Primary Uses Mucanix Injection is primarily used for: • Respiratory Disorders: Conditions such as chronic bronchitis, asthma, and cystic fibrosis, where there is excessive mucus production. • Paracetamol (Acetaminophen) Overdose: As an antidote to prevent liver damage when administered within 8 hours of overdose. ________________________________________ ⚙️ Mechanism of Action Acetylcysteine works by: • Breaking down mucus: It reduces the viscosity of mucus, facilitating easier expectoration. • Restoring glutathione levels: In cases of paracetamol overdose, it replenishes glutathione, a vital antioxidant, aiding in detoxification and protecting the liver. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Allergy: Do not use if allergic to acetylcysteine or any of its components. • Asthma: Use with caution in patients with asthma; monitoring is required. • Pregnancy and Breastfeeding: Consult a doctor before use during pregnancy or breastfeeding. Common Side Effects: • Nausea • Vomiting • Rash • Fever • Headache Serious Side Effects: • Anaphylactic reactions (rare) • Hypotension • Tachycardia If you experience any of these serious side effects, seek immediate medical attention.

Hepabig 100IU Injection helps to protect you against hepatitis B (a virus that damages the liver). It is used to prevent hepatitis B after exposure to contaminated blood through sexual contact, accidental needle prick injury, from an infected mother to her newborn or after a liver transplant. Hepabig 100IU Injection is normally given along with the hepatitis B vaccine. It comes from human blood plasma and is given by an injection into a large muscle such as your thigh or buttock. Your doctor will inject the prescribed dose after analyzing your condition. It should be given as soon as possible after the risk of infection is identified. If it is delayed too long, it may not be effective. This medicine is not a vaccine and will not provide long-term protection from hepatitis B. This medicine may sometimes cause side effects like flushing, gastrointestinal disturbance (stomach pain and upset, nausea, vomiting), headache, dizziness, and injection site reactions (pain, swelling, and redness). If you get any of these, or other reactions, or just feel unwell, you should tell your doctor. There may be ways of preventing or reducing these effects. Any serious reaction to the injection is rare.