Blink 7 EYE DROPS contains Hydroxypropyl methylcellulose, which belongs to the group of medicines called Demulcents. It is used to alleviate dry eye conditions by substituting tear fluid in affected individuals. It is also used to provide temporary relief from burning irritation from dryness of the eye. Blink 7 EYE DROPS is not recommended for use in patients allergic to hydroxypropyl methylcellulose. It is also not recommended for use if you are undergoing any surgery. Before administering Blink 7 EYE DROPS, inform your doctor if you wear contact lenses. Blink 7 EYE DROPS should be used with caution in pregnant and breastfeeding women. It should be used with caution in children and elderly patients. Consult your doctor before using. The most common side effects of administering Blink 7 EYE DROPS are eye irritation/redness, itchy eyes, blurred vision, and/or eye pain. Consult your doctor if any of these symptoms worsen. Uses Of Blink 7 EYE DROPS Alleviates dry eye conditions Provides temporary relief from burning sensation due to dryness of eye How Blink 7 EYE DROPS Works Blink 7 EYE DROPS is a hydrophilic polymer that works by crosslinking on the eye surface, resulting in increased tear clearance time and promoting eye lubrication, thus providing relief from symptoms associated with eye dryness in affected individuals. How to use Blink 7 EYE DROPS Use Blink 7 EYE DROPS as advised by your physician. It is for ophthalmic use only. Place the recommended number of gel drops inside the lower eyelid by squeezing the container. Do not use this product if its colour changes or becomes cloudy. Do not touch the container tip to avoid any contamination. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition. Side Effects Of Blink 7 EYE DROPS Common Eye irritation/redness Blurred vision Itchy eye Eye pain

Dobier S 50mg Injection Salt: Dobutamine (50mg) INTRODUCTION ABOUT DOBIER S 50MG INJECTION DOBIER S 50MG INJECTION contains Dobutamine which belongs to the group of medicines called Cardiac Stimulants. It is used to improve heart functions. It restores heartbeat and blood pressure to normal levels among patients undergoing open heart surgery and in patients having heart failure or any other severe heart conditions that reduces heart rate (such as shock or cardiomyopathies (enlargement of heart muscles)). It can also be used as an alternative to exercise during stress testing (a procedure used to detect heart problems). DOBIER S 50MG INJECTION is suitable for use both in adults and in children (including infants). Before receiving DOBIER S 50MG INJECTION inform your doctor if you have asthma or any other respiratory disorders. You must also inform your doctor if you have any allergic conditions or low blood volume as a precaution. DOBIER S 50MG INJECTION is not suitable for stress testing in patients having any heart or blood vessels disorders that hinder blood flow. It is also not recommended for use in pregnant and in breastfeeding women unless considered necessary by the physician. The most common side effects of receiving DOBIER S 50MG INJECTION are fast heartbeat, headache, high or low blood pressure, shortness of breath, inflammation at the injection site, nausea and urge to pass urine. Consult your doctor if any of these side effects worsens. USES OF DOBIER S 50MG INJECTION Improves heart functions by restoring normal heartbeat and blood pressure Manage heart failure Manage shock (cardiogenic or septic shock) Manage any heart conditions that may result in poor circulation around the body (such as cardiomyopathies, open heart surgery) Used as an alternative to exercise during stress testing HOW DOBIER S 50MG INJECTION WORKS DOBIER S 50MG INJECTION is a cardiac stimulant. It stimulates the heart and improves heart functions. It helps your heart to work more effectively by strengthening the pumping action of the heart. It also improves blood circulation around the body by expanding the blood vessels present all over the body. DIRECTIONS FOR USE DOBIER S 50MG INJECTION will be given only by a doctor or by a trained healthcare professional into the vein (intravenously). Your doctor will decide the correct dose, duration of therapy and site of administration for you depending upon your age, body weight and health condition. SIDE EFFECTS OF DOBIER S 50MG INJECTION COMMON increased heart rate chest pain abnormal heartbeat, palpitations high or low blood pressure narrowing of the blood vessels headache wheezing, shortness of breath increase in WBC count in blood increased bleeding tendency urge to pass urine nausea skin rash fever inflammation at the injection site HOW TO MANAGE SIDE EFFECTS Headache: Try to take rest. Apply a pain-relieving balm on your forehead. If the symptom does not improve, consult with your doctor. Nausea: Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your symptom worsens. Skin rash: Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash worsens. Inflammation at the site of injection: Place an ice pack on the injected site. Do not move the affected area frequently. If the symptom worsens, consult your doctor. WARNING & PRECAUTIONS PREGNANCY DOBIER S 50MG INJECTION is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, inform your doctor before receiving this medicine if you are pregnant or think you may be pregnant or planning to have a baby. BREASTFEEDING DOBIER S 50MG INJECTION is not recommended for use in breastfeeding women. Therefore, inform your doctor before receiving this medicine if you are breastfeeding. DRIVING AND USING MACHINES Do not drive or operate any machines if your ability is affected by DOBIER S 50MG INJECTION. ALLERGY Do not receive DOBIER S 50MG INJECTION if you are allergic to Dobutamine. LUNGS DOBIER S 50MG INJECTION should be used with caution in patients with asthma or any allergic or respiratory conditions. Therefore, consult your doctor before receiving it. HEART DISEASE DOBIER S 50MG INJECTION is not recommended for use in patients who have narrowing of blood vessels supplying the heart (coronary artery stenosis) or other heart disorders. It should be used with caution in patients with other heart problems (such as coronary artery disease, or acute heart failure). Therefore, consult your doctor before receiving it. OTHERS DOBIER S 50MG INJECTION is not recommended for use if you: have low blood volume (hypovolaemia) have any disorders in the blood vessels that hinders blood flow Before receiving DOBIER S 50MG INJECTION, inform your physician if you:

About I-Dox 20Mg/10Ml Inj I-Dox 20Mg/10Ml Inj is an anti-cancer medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. I-Dox 20Mg/10Ml Inj is primarily used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer (abnormal growth in the cells of the breast). It is also used to treat neuroblastoma (cancer that starts in nerve cells and primarily affects children) and Wilms' tumor (a form of kidney cancer that affects children). I-Dox 20Mg/10Ml Inj contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, destroying DNA and RNA synthesis. I-Dox 20Mg/10Ml Inj may cause certain side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, dizziness, mouth sores, tiredness, back pain, red discoloration of urine, diarrhea, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare doctor will administer I-Dox 20Mg/10Ml Inj. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition. I-Dox 20Mg/10Ml Inj should be avoided if you are allergic to it or any other components of this medicine. It is contraindicated in patients having severe myocardial insufficiency, a recent history of myocardial infarction (MI), severe persistent drug-induced myelosuppression, and severe liver disease. Hence, if you have any such conditions, inform your doctor. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any CYP3A4 or CYP2D6 inducers medication, as it can cause adverse effects. I-Dox 20Mg/10Ml Inj is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand. Uses of I-Dox 20Mg/10Ml Inj Treatment of Breast Cancer Directions for Use A trained healthcare professional will administer I-Dox 20Mg/10Ml Inj. Hence, do not self-administer. Medicinal Benefits I-Dox 20Mg/10Ml Inj contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. I-Dox 20Mg/10Ml Inj is also used in the treatment of acute lymphoblastic leukaemia, acute myeloblastic leukaemia, Hodgkin lymphoma, Non-Hodgkin lymphoma, metastatic breast cancer, metastatic Wilms’ tumour, metastatic neuroblastoma, metastatic soft tissue sarcoma, metastatic bone sarcomas, metastatic ovarian carcinoma, metastatic transitional cell bladder carcinoma, metastatic thyroid carcinoma, metastatic gastric carcinoma, metastatic bronchogenic carcinoma. How I-Dox 20Mg/10Ml Inj Works I-Dox 20Mg/10Ml Inj contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, destroying DNA and RNA synthesis. Storage Store in a cool and dry place away from sunlight Side Effects of I-Dox 20Mg/10Ml Inj Nausea Abdominal pain Vomiting Dizziness Back pain Pain at the site of injection Red discolouration of urine Loss of appetite Mouth sores Tiredness Weight gain What if I have taken an overdose of I-Dox 20Mg/10Ml Inj Since I-Dox 20Mg/10Ml Inj is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of I-Dox 20Mg/10Ml Inj may cause sores in the mouth and throat, fever, sore throat, chills, or other signs of infection, unusual bleeding or bruising, black and tarry stools, red blood in stools, and bloody vomit or vomited material that looks like coffee grounds. Drug Warnings I-Dox 20Mg/10Ml Inj should be avoided if you are allergic to it. It is contraindicated in patients having severe myocardial insufficiency, a recent history of myocardial infarction (MI), severe persistent drug-induced myelosuppression and severe liver disease. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any CYP3A4 or CYP2D6 inducers medication, as it can cause serious adverse effects. I-Dox 20Mg/10Ml Inj is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. Do not stop receiving I-Dox 20Mg/10Ml Inj without a doctor’s advice, as it can cause serious health conditions. I-Dox 20Mg/10Ml Inj is known to cause secondary malignancies.

INTRODUCTION ABALAM 600/300 is a combination of Abacavir and Lamivudine which belongs to the group of medicines called Anti-viral agents. It is used in the management of HIV infection in adults, adolescents and in children (weighing above 25 kgs). HIV (human immunodeficiency virus) infection is a viral infection that damages our immune system and weakens our body’s ability to fight against various infections. Both abacavir and lamivudine are nucleoside reverse transcriptase inhibitors. They work by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. This prevents further multiplication of viral cells within the body. Also, they can improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. ABALAM 600/300 cannot not manage HIV infection completely. It can reduce only the number of viral cells present in the body and maintains them at a lower level. During management with ABALAM 600/300 your doctor will closely monitor your body weight, blood cholesterol levels and blood sugar levels to reduce the risk of unwanted side effects. Do not take ABALAM 600/300 if you are allergic to abacavir or lamivudine. Before taking ABALAM 600/300 inform your doctor if you have diabetes or any liver (hepatitis C or B infection), kidney or heart problems. If you are already taking ABALAM 600/300 to manage hepatitis B or C infection, do not stop taking it without consulting your doctor. Even if you take ABALAM 600/300, it is important for you to follow certain measures to prevent the spread of infections to the other people (such as avoid having unprotected sexual intercourse or sharing needles or personal items like toothbrush, razors etc with other people). ABALAM 600/300 is not recommended for use in pregnant or breastfeeding women. The most common side effects of taking ABALAM 600/300 are difficulty in sleeping, increased signs of infections, nausea, stomach pain, headache, or dizziness. Consult your doctor if any of these side effects worsens. Also inform your doctor immediately if you experience severe fever with extreme tiredness, sudden changes in body weight or severe stomach pain along with dark urine after taking ABALAM 600/300. USES OF ABALAM 600/300 Manages HIV infection in adults, adolescents and in children (weighing above 25 kgs) HOW ABALAM 600/300 WORKS ABALAM 600/300 is an anti-retroviral medicine. It controls the multiplication of viral cell within the body, by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. It can also improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. DIRECTIONS FOR USE Take ABALAM 600/300 as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. ABALAM 600/300 can be taken with or without meals. Your doctor will decide the correct dose and for how long ABALAM 600/300 must be taken depending upon your age, body weight and severity of the infection. Do not stop taking ABALAM 600/300 without consulting your doctor as it may reduce its effectiveness. SIDE EFFECTS OF ABALAM 600/300 COMMON difficulty in sleeping feeling depressed headache, tiredness, dizziness nausea, diarrhoea fever, skin rash stomach pain loss of appetite irritated or runny nose hair loss UNCOMMON decrease in RBC, WBC, and platelets RARE Stop taking ABALAM 600/300 and contact your doctor immediately if you experience any of the following side effects: signs of allergic reactions (such as skin rash, fever, accompanied with sore throat, cough, nausea, vomiting, stomach pain, diarrhea, tiredness, joint pain, muscle pain, swelling of the neck, difficulty in breathing, mouth ulcers, occasional headaches, inflammation of the eye, low blood pressure, sense of tingling or numbness of hands or feet) pure red cell aplasia (failure of bone marrow to produce new red blood cells) signs of infections (such as fever, headache, stomach-ache, breathing difficulty) signs of auto-immune disorders (such as rapid or irregular heartbeat, tremor, hyperactivity, general weakness) signs of osteonecrosis (death of bone cells causing joint stiffness, pain in the hip, knee or shoulder and difficulty in moving) signs of liver problems (such as yellowing of the skin and whites of the eye, dark urine, light-coloured stools, loss of appetite, nausea, pain, tenderness on the right side of stomach) heart attack changes in body fat (such as increase fat in the shoulder and neck (buffalo hump), breast, and in the middle body or fat loss from the legs, arms, or face)

Marketer Neon Laboratories Ltd SALT COMPOSITION Megestrol (160mg) Storage Store below 30°C Uses of Neostrol Tablet Breast cancer Endometrial cancer Product introduction Neostrol 160mg Tablet is used to treat breast cancer and endometrial cancer. It specifically helps treat breast and endometrial cancer that are hormone dependent. It may also be used for treating low appetite and weight loss in patients with advanced cancer or HIV. Neostrol 160mg Tablet should be taken as your doctor advice. Your doctor will decide how much you need to take and for how much time. You may take it with or without food but better to take it at a fixed time. You should take this medicine for as long as it is prescribed for you. The most common side effects of this medicine include weight gain, increase in appetite, shortness of breath, hot flushes (warm face and neck), high blood pressure, and constipation. Most of these are temporary, and go away as soon as the body adjusts to the treatment. If any of these bothers you, let your doctor know. There may be ways of reducing or preventing them. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Pregnant and breastfeeding women should not take this medicine. Your doctor might do regular blood tests to check your hormones and blood sugar levels while you are taking this medicine. Benefits of Neostrol Tablet In Breast cancer Neostrol 160mg Tablet relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples, or changes in the shape or texture of the breast. It works by altering the production of those hormones in the body that are essential for the growth and spread of breast cancer. It may also interact with other hormones or have a direct effect on the cancer to stop its growth. In Endometrial cancer Neostrol 160mg Tablet is a synthetic hormone which replicates the effect of a natural female hormone called progesterone. It relieves the symptoms of endometrial cancer (a type of cancer that develops in the lining of the womb) such as, abnormal vaginal bleeding, lower back pain, pain during sex, etc. It interferes with the production and working of those hormones in the body that are essential for the growth and spread of endometrial cancer. It may also interact with other hormones or have a direct effect on the cancer to stop its growth. Side effects of Neostrol Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Neostrol Increased appetite Weight gain Hot flashes High blood pressure Constipation How to use Neostrol Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Neostrol 160mg Tablet may be taken with or without food, but it is better to take it at a fixed time. How Neostrol Tablet works Neostrol 160mg Tablet is a progestin (female hormone). It works in patients with breast cancer and endometrial cancer by affecting female hormones involved in cancer growth. It causes weight gain by increasing appetite.

INTRODUCTION ABOUT VALCYTE 450MG TABLET VALCYTE 450MG TABLET contains Valganciclovir which belongs to the group of medicines called Antiviral agents. It is used in adults (with acquired immunodeficiency syndrome) to manage cytomegalovirus (CMV) infection of the retina of the eye which generally cause vision problems and blindness. VALCYTE 450MG TABLET is also used in adults and children to manage cytomegalovirus (CMV) infection who are not infected with CMV or who had received an organ transplant from someone who earlier had CMV infection. VALCYTE 450MG TABLET is not recommended for use in patients allergic (hypersensitive) to Valganciclovir, and/or Ganciclovir. Before taking VALCYTE 450MG TABLET, inform your doctor if are undergoing radiotherapy/hemodialysis, and/or suffer from low red blood cell, white blood cell or platelets, kidney/liver problems. VALCYTE 450MG TABLET is not recommended for use in pregnant women unless it is clearly necessary since it may cause harm to the unborn baby. It is also not recommended for use in breastfeeding women. VALCYTE 450MG TABLET should be used with caution in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 65 years and above) after consulting the doctor. The most common side effects of taking VALCYTE 450MG TABLET are oral thrush (fungal infection), headache, shortness of breath, abdominal pain, loss of appetite, nausea, vomiting, and/or diarrhea. Consult your doctor if any of these symptoms worsens. USES OF VALCYTE 450MG TABLET Manage cytomegalovirus (CMV) infection of the retina of the eye in adult patients with acquired immunodeficiency syndrome (AIDS). Prevents cytomegalovirus (CMV) infection who are not infected with CMV or in patients who had received an organ transplant from someone who earlier had CMV infection HOW VALCYTE 450MG TABLET WORKS VALCYTE 450MG TABLET works by managing the multiplication of virus in human cells by decreasing its growth which results in inhibition of production of new virus thus managing and managing the spread of infection to other parts of the body in affected individuals. DIRECTIONS FOR USE Take VALCYTE 450MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF VALCYTE 450MG TABLET COMMON thrush & oral thrush (fungal infection) upper respiratory tract infection such as sinusitis, tonsillitis headache cough, shortness of breath abdominal pain, loss of appetite, nausea/vomiting, diarrhea, weight loss eczema (skin inflammation) tiredness, fever influenza signs of urine infection such as fever, passing urine more often, and/or pain (while passing urine) skin infection signs of mild allergic reaction such as red, itchy skin feeling depressed, anxious or confused trouble sleeping feeling numb/weak in hands/feet changes in sense of touch, tingling/tickling/pricking/burning sensation altered taste, chills eye inflammation/pain or sight problems ear pain signs of low blood pressure such as feeling dizzy/faint difficulty while swallowing constipation, wind, indigestion, stomach pain, swelling of abdomen mouth ulcers night sweats itching, rash hair loss back pain, muscle/joint pain, muscle spasms feeling dizzy, weak/generally unwell UNCOMMON feeling agitated tremor/shaking deafness irregular heartbeat red itchy welt, dry skin blood in urine chest pain RARE Stop taking VALCYTE 450MG TABLET and contact your doctor if you experience any of the following side effects: signs of allergic reaction (anaphylactic shock) such as raised, itchy skin rash, sudden swelling of throat, face, lips/mouth resulting in difficulty while swallowing/breathing, and/or sudden swelling of the hands, feet/ankles. signs of infection (due to low white blood cell count) such as sore throat, mouth ulcer, and/or fever signs of low red blood cell count such as shortness of breath, tiredness, palpitation, and/or pale skin signs of blood infection (sepsis) such as fever, chills, palpitation, confusion, and/or slurred speech signs of low platelet count such as bleeding/bruising, blood in urine/stools, and/or bleeding from gums severely low blood cell count pancreatitis (inflammation of pancreas) associated with severe stomach pain fits hallucinations abnormal thoughts/feelings, losing contact with reality failure of kidney function HOW TO MANAGE SIDE EFFECTS Constipation Try to eat high-fiber foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise (such as going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate managements for constipation.

Combinib 250mg Tablet is used in the treatment of breast cancer. It works by stopping or slowing down the growth of cancer cells. It is either used alone or in combination with some other medicine to cure advanced-stage breast cancer. Combinib 250mg Tablet should be taken on an empty stomach or an hour before or 2 hours after a meal. The dose and duration vary according to the severity of your condition and your response to treatment. Take it exactly as prescribed to avoid serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include nausea, headache, back pain, and breathing difficulty. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. You may be asked for regular monitoring of blood pressure while taking this medicine. Inform your doctor if you notice a severe headache, confusion, problems with your eyesight, nausea, or vomiting. Your doctor may check your liver function before, during, and after treatment with this medicine. Before taking Combinib 250mg Tablet, let your doctor know if you have liver or kidney problems. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are taking. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details. Uses of Combinib Tablet Pancreatic cancer Small cell lung cancer Liver cancer Kidney cancer Thyroid cancer Blood cancer (Chronic myeloid leukaemia) Gastrointestinal stromal tumour Cancer of colon and rectum Non-small cell lung cancer Soft tissue sarcoma Chronic idiopathic myelofibrosis Breast cancer Side effects of Combinib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Combinib Abdominal pain Back pain Breathing problems Constipation Cough Diarrhea Fatigue Headache Hot flashes Increased bilirubin in the blood Insomnia (difficulty in sleeping) Joint pain Liver damage Loss of appetite Mucosal inflammation Nausea Pain in extremities Rash Stomatitis (Inflammation of the mouth) Vomiting Weakness Weight gain How to use Combinib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combinib 250mg Tablet is to be taken empty stomach. How Combinib Tablet works Combinib 250mg Tablet is an anti-cancer medication. It works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which are responsible for the over-proliferation of cells. This is how it inhibits the growth of cancerous cells causing downstream signaling pathways. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Combinib 250mg Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Combinib 250mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Combinib 250mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Combinib 250mg Tablet may cause side effects which could affect your ability to drive. warnings Kidney CAUTION Combinib 250mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Combinib 250mg Tablet may be needed. Please consult your doctor. Limited information is available on the use of Combinib 250mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease. warnings Liver CAUTION Combinib 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Combinib 250mg Tablet may be needed. Please consult your doctor. Limited information is available on the use of this medicine in patients with the severe liver disease.

Temolon 100mg Capsule contains the active ingredient temozolomide. It belongs to the class of medications known as Antitumor agents. It is prescribed to treat brain cancer, such as glioblastoma multiforme in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma in patients older than three years. Glioblastoma and anaplastic astrocytoma are the most common and aggressive brain cancers with low chances of survival. Anaplastic astrocytoma is treated with Temolon 100mg Capsule or radiotherapy after biopsy, whereas Glioblastoma multiforme is treated with a combination of radiotherapy and Temolon 100mg Capsule, and it is continued as maintenance therapy. The common side effects that are likely to associate with Temolon 100mg Capsule are nausea, vomiting, dizziness, diarrhea, constipation, hair loss, rashes, tiredness, frequent urination, vision and hearing problems, high blood sugar levels, muscle damage, pain in muscles and joints, memory loss, coordination problems, infections, sleep problems and loss of weight. Inform your doctor if any of these symptoms disturb you or persist.

Marketer BDR Pharmaceuticals Internationals Pvt SALT COMPOSITION Sorafenib (200mg) Storage Store below 30°C Uses of Livonibe Tablet Pancreatic cancer Small cell lung cancer Liver cancer Kidney cancer Thyroid cancer Blood cancer (Chronic myeloid leukaemia) Gastrointestinal stromal tumour Cancer of colon and rectum Non-small cell lung cancer Soft tissue sarcoma Chronic idiopathic myelofibrosis Breast cancer Product introduction Livonibe 200mg Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer. Livonibe 200mg Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Fatigue, nausea, loss of appetite, hair loss and diarrhea are some common side effects of this medicine. It might cause high blood pressure, so the doctor may ask you for a regular check-up of blood pressure. You must inform your doctor if you notice severe skin reaction such as skin rash, or any pain, swelling, and redness of your hands and feet. Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or high blood pressure. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Side effects of Livonibe Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Livonibe Fatigue Nausea Loss of appetite Diarrhea Abdominal pain Hair loss Weight loss Rash Painful blisters on hands and feet How to use Livonibe Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Livonibe 200mg Tablet is to be taken empty stomach. How Livonibe Tablet works Livonibe 200mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Livonibe 200mg Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Livonibe 200mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Livonibe 200mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving SAFE Livonibe 200mg Tablet does not usually affect your ability to drive. warnings Kidney SAFE IF PRESCRIBED Livonibe 200mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Livonibe 200mg Tablet is recommended. Regular monitoring of blood tests may be advised while you are taking this medicine. warnings Liver CAUTION Livonibe 200mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Livonibe 200mg Tablet may be needed. Please consult your doctor.