Cyclomune 0.05% About the brand Cyclomune is brand of Sun Pharmaceuticals having salt Cyclosporine. Sun Pharmaceuticals is one of biggest generic drug manufacturer throughout global markets. It has served more than 150 markets globally. It has more than 2000 marketed products and is the leading pharmaceutical drug company of India. About the drug Cyclomune is drug having Cyclosporine as salt. Cyclosporine eye drops work differently as compared to cyclosporine used in different dosage forms. Cyclosporine is an immunosuppressant drug. It interferes with the immune system of the body. Cyclosporine eye drops help in curing the dry eye condition when used as an ophthalmic solution. Manufacturer of the drug Cyclomune is manufactured by Sun Pharmaceutical in India. Strength of the drug The 3 ml solution of Cyclomune contains 0.5 % strength of Cyclosporine. USA equivalent brand Restasis is the US brand equivalent to Cyclomune available in USA markets. Uses of the drug Cyclomune is used for dry eye conditions. It has proven effects to cure chronic dry eye conditions. How does it work? As an eye drop, Cyclomune works as a partial modulator of the immune system. Tear production in the eyes gets lowered due to the accumulation of dead lymphocytes cells in tear glands. Cyclomune eye drops works by reversing the cycle and hence helps in increasing the tear production from tear glands. How to take the drug? Take the medicine as directed by your physician. It should be taken twice in a day with a gap of 12 hours in between in both eyes. Efforts shall be made to take the drug drops the same time every day. Dosage needed Cyclomune eye drops shall be taken twice in a day. For correct dosage take your physician advice and guidelines. How long should drug to be continued? It shall be continued as directed by your doctor. Do not overdose yourself with the eye drops. What if you miss the dosage? Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not instill a double dose to make up for a missed one. Drug interaction with other More than 800 drug interactions have been reported with use of Cyclosporine. It interacts with atorvastatin, aspirin, Calcium 600 D, docusate, amlodipine, pregabalin, Zyrtec etc. When not to take the drug Avoid taking the drug if you are allergic to any of the constituents of the drug Cyclomune. Consult your doctor for further advise. Side effects of intake Side effects associated with the drug are, burning, itching, stinging, redness, or pain of the eyes overflow of tears red eyes eye discharge blurred vision or other vision changes feeling that something is in the eye Overdose effects Shaking, headache, dizziness, unusual growth of body hair, nausea/vomiting, diarrhea, stomach upset, flushing or Unusual growth and swelling of the gums may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. General information and precautions Do not let anyone else use your medication. Ask your pharmacist any doubts you have about refilling your prescription. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. carry this list with you every time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Timipar (Timolol Maleate 0.5%) Ophthalmic Solution is a prescription eye drop used to manage elevated intraocular pressure (IOP) in conditions such as open-angle glaucoma and ocular hypertension. By reducing the production of fluid within the eye, it helps lower IOP, thereby reducing the risk of optic nerve damage and potential vision loss. ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common form of glaucoma where the drainage angle in the eye remains open, but the trabecular meshwork is partially blocked, leading to increased IOP. • Ocular Hypertension: A condition characterized by higher-than-normal IOP without any signs of glaucoma damage. ________________________________________ 💊 Dosage and Administration • Typical Dosage: Instill one drop of the 0.5% solution into the affected eye(s) twice daily. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. o After instilling the drop, gently press the corner of your eye (near the nose) for 1–2 minutes to prevent the medication from draining out. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Bronchial asthma or a history of bronchial asthma. o Severe chronic obstructive pulmonary disease (COPD). o Sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock. • Cautions: o Use with caution in patients with a history of heart disease, diabetes, or thyroid disorders, as beta-blockers can mask symptoms of hypoglycemia and hyperthyroidism. o Monitor for potential additive effects when used with other systemic beta-blockers. ________________________________________ 🧪 Mechanism of Action Timolol is a non-selective beta-adrenergic antagonist (beta-blocker) that reduces aqueous humor production in the eye, leading to a decrease in IOP. Its onset of action is typically within 20 minutes, with effects lasting up to 24 hours.

Timipar (Timolol Maleate 0.25%) eye drops are a prescription medication primarily used to manage elevated intraocular pressure (IOP) associated with conditions like open-angle glaucoma and ocular hypertension. By reducing the production of aqueous humor, the fluid inside the eye, Timolol helps lower IOP, thereby reducing the risk of optic nerve damage and potential vision loss . ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common type of glaucoma where the drainage angle in the eye remains open, but the trabecular meshwork is partially blocked, leading to increased IOP. • Ocular Hypertension: A condition characterized by higher-than-normal IOP without any signs of glaucoma damage. ________________________________________ 💊 Dosage and Administration • Typical Dosage: Instill one drop of the 0.25% solution into the affected eye(s) once or twice daily, as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them . ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Bronchial asthma or a history of bronchial asthma. o Severe chronic obstructive pulmonary disease (COPD). • Sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock . • Cautions: o Use with caution in patients with a history of heart disease, diabetes, or thyroid disorders, as beta-blockers can mask symptoms of hypoglycemia and hyperthyroidism. o Monitor for potential additive effects when used with other systemic beta-blockers . ________________________________________ 🧪 Mechanism of Action Timolol is a non-selective beta-adrenergic antagonist (beta-blocker) that reduces aqueous humor production in the eye, leading to a decrease in IOP. Its onset of action is typically within 20 minutes, with effects lasting up to 24 hours .

FLURACIL 250MG INJECTION contains Fluorouracil, which belongs to a group of medicines called Nucleoside metabolic inhibitors. FLURACIL 250MG INJECTION is used to manage cancer involving the breast, oesophagus, stomach, colon, rectum, pancreas, prostate, ovary, bladder, and head and neck cancer. FLURACIL 250MG INJECTION should not be used in patients with serious infections (for example, Herpes zoster or chickenpox), non-malignant tumours, poor nutrition, weakened immunity due to long illness, damaged bone marrow due to other antineoplastics or radiotherapy, severe liver disease, or homozygotic or complete deficiency of dihydropyrimidine dehydrogenase (DPD) enzyme. FLURACIL 250MG INJECTION should be used with caution in patients with decreased blood cells, oral ulcers, fever or haemorrhage at any site or weakness (due to decreased blood cells), kidney or liver problems like jaundice (yellowing of the skin) or heart problems like chest pain, reduced activity or deficiency of the enzyme DPD (dihydropyrimidine dehydrogenase), had high-dose radiation to pelvic, spine, ribs, metastatic tumours with involvement of bone marrow, severe bone marrow suppression include neutropenia, thrombocytopenia, and anaemia, viral, bacterial, fungal and/or parasitic infections, encephalopathy, gastrointestinal side effects like stomatitis, diarrhoea, bleeding from the G.I. tract or haemorrhage at any site, family history of partial or complete deficiency of the enzyme dihydropyrimidine dehydrogenase (DPD), had recent major surgery.