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'oxidative stress toxicity'

Items tagged with 'oxidative stress toxicity'

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Cats and Dogs

Taurians contains 2 potent anti-oxidants – N-acetyl cysteine & Taurine. Taurine is an amino acid that both dogs and cats require for good health. For cats, taurine is necessary for brain, nerves, eyes, heart, digestion, immune function and fetal development. For dogs, taurine is needed for eyes, reproduction, bile acid (for fat digestion) and for healthy heart. N-Acetylcysteine is useful in treating conditions that involve tissue damage due to oxidative stress and toxicity, Taurians helps to protect against damage from oxidative stress in patients with chronic kidney disease, reduces risk of cardiovascular disease, promotes healthy liver, prevents or reduces glomerular damage due to diabetes, and promotes clean & healthy lungs.

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General Medicine

Acetylcysteine (N-Acetylcysteine or NAC) Injection is a medication with various clinical uses, particularly in treating acute poisoning and respiratory conditions. It is the injectable form of NAC, which is also available in oral and inhalation formulations. 🔹 Common Uses of Acetylcysteine Injection (NAC Injection): 💊 Acetaminophen (Paracetamol) Overdose: Primary and well-established use: Acetylcysteine is the antidote for acetaminophen toxicity (overdose). It works by replenishing glutathione, a crucial antioxidant in the liver, thus preventing liver damage caused by acetaminophen metabolism. Early administration is key: Can prevent or minimize liver damage if administered within 8–10 hours of overdose. 🫁 Chronic Obstructive Pulmonary Disease (COPD) / Respiratory Conditions: Mucolytic action: NAC helps to break down and thin mucus in the lungs, making it easier to cough up. Often used in COPD, chronic bronchitis, asthma, and other conditions where thick mucus obstructs airways. Nebulized NAC is sometimes used for inhalation to directly treat respiratory conditions. 🧬 Kidney Protection (Preventing Contrast-Induced Nephropathy): Prophylactic use in patients who are at high risk of contrast-induced kidney damage (e.g., before receiving contrast media in imaging procedures like CT scans). NAC may help protect kidney function from damage caused by the contrast agents used during these procedures. 🔬 Antioxidant Therapy in Critical Care: NAC is used as an antioxidant to reduce oxidative stress in various conditions such as sepsis, acute respiratory distress syndrome (ARDS), and other critical illnesses. It helps to reduce inflammation and cell damage by neutralizing free radicals. 🧪 Treatment of Cystic Fibrosis (CF): While primarily in oral or nebulized form, acetylcysteine may sometimes be used intravenously to help manage mucus buildup in the airways in CF patients, although this is less common. 🍸 Alcohol-Induced Liver Injury: NAC has been investigated in treating alcohol-induced liver damage, as it helps with glutathione replenishment and reduces oxidative stress. It’s sometimes used in the hospital setting for patients with alcoholic liver disease. 💉 How It’s Administered: Intravenously (IV) is the most common method for acetaminophen overdose or critical care. It is usually given as a slow infusion, with the dosage adjusted based on the severity of the condition being treated (e.g., for acetaminophen toxicity, a specific dosing regimen is followed). ⚠️ Precautions & Side Effects: Common Side Effects: Nausea or vomiting (especially with high doses) Rash Fever Hypotension (low blood pressure) during IV administration Severe Reactions: Rarely, an allergic reaction (e.g., anaphylaxis) may occur. Bronchospasm (tightening of the airways) in patients with a history of asthma, though this is less common with IV use. Kidney function should be monitored, especially in patients at high risk of renal issues or those receiving contrast agents. ✅ Summary of Acetylcysteine Injection Uses: Condition Use of Acetylcysteine (NAC) Injection Acetaminophen overdose ✅ Primary antidote Mucolytic (thinning mucus) for respiratory conditions ✅ COPD, chronic bronchitis, asthma Kidney protection in contrast nephropathy ✅ Prevent contrast-induced kidney damage Antioxidant therapy in critical care ✅ Sepsis, ARDS, oxidative stress Cystic Fibrosis (mucus management) ✅ Less common, but used Alcohol-induced liver injury ✅ Investigational (glutathione replenishment)

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General Medicine

Glutathione Injection is widely used in both medical and cosmetic settings. It’s a powerful antioxidant naturally produced in the body, and injectable forms are often used when higher or faster delivery is needed. 🔹 Medical Uses of Glutathione Injection: 🧬 Antioxidant Therapy (Cell Protection) Neutralizes free radicals, reduces oxidative stress. Used in chronic illnesses like diabetes, neurodegenerative diseases, and liver disease. 🫁 Chronic Illness Support May help in conditions like: Parkinson’s disease (as an experimental treatment) Fatty liver disease / Hepatitis HIV/AIDS (to reduce oxidative stress) 🧪 Detoxification Supports liver detox in heavy metal toxicity, drug overdose, and chemotherapy side effects. 💊 Chemotherapy Side Effect Reduction Sometimes used to protect healthy cells during chemo, particularly in reducing neurotoxicity. ✨ Cosmetic & Wellness Uses (Off-label): 🌟 Skin Whitening / Brightening Popular in aesthetics for skin lightening, often combined with vitamin C. Works by inhibiting melanin production, but results vary and are not FDA-approved for this use. 💆 Anti-Aging & Skin Health Promoted for improving skin clarity, elasticity, and reducing pigmentation. Marketed in many wellness clinics as a 'glow' or beauty drip. 💉 How It’s Administered: Usually given via IV (intravenous) or IM (intramuscular). Dosing depends on purpose: medical doses tend to be lower; cosmetic doses are often higher and given in repeated sessions. ⚠️ Side Effects & Precautions: Generally well-tolerated in low doses, but possible side effects include: Nausea Skin rashes Breathing difficulty (rare) High-dose or long-term use should be done under medical supervision, especially in people with asthma or kidney/liver disease.

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General Medicine

Ascorbic Acid Injection (Vitamin C Injection) is a sterile, injectable form of Vitamin C (ascorbic acid), used in medical settings where high or immediate doses are needed, or when oral intake is not possible. 🔹 Main Uses of Ascorbic Acid Injection: 💉 Treatment of Vitamin C Deficiency / Scurvy When dietary intake is inadequate or absorption is impaired. Symptoms: fatigue, swollen gums, joint pain, poor wound healing. 🛡️ Immune System Support Supports immune function in infections, post-surgery recovery, or critically ill patients. 🩸 Iron Absorption Enhancement Given with iron supplements to improve iron absorption in patients with iron-deficiency anemia. 🔥 Wound Healing & Collagen Production Enhances tissue repair after burns, trauma, or surgery. 🧬 Antioxidant Therapy Reduces oxidative stress in conditions like sepsis, cancer, and chronic diseases. 🧪 Adjunct Therapy in Cancer (Experimental) High-dose IV vitamin C is studied as a supportive treatment in cancer therapy (under specialist care). 🧼 Detoxification Occasionally used as part of detox protocols in heavy metal poisoning or drug toxicity. ⚕️ Critical Illness Support Used in ICUs for patients with infections, sepsis, or acute respiratory distress syndrome (ARDS) as part of antioxidant therapy. 💉 How It’s Given: Usually IV (intravenous) for quick absorption, or IM (intramuscular). Dose depends on the clinical situation—can range from standard supplementation to high-dose IV therapy. ⚠️ Precautions & Side Effects: Generally safe, but high doses may cause: Kidney stones (especially in those with kidney issues) Diarrhea or stomach upset Hemolysis in G6PD-deficient patients (rare but serious) Regular monitoring may be needed in high-dose or long-term therapy.

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Cats and Dogs

Oscinap is a combination of N-Acetyl Carnosine (NAC) & Sodium Carboxymethyl celulose (SCMC). Oscinap strengthens eye’s defence against free radicals and prrevents progression of cataracts in cats & dogs. N-Acetyl Carnosine penetrates the eye and gets further metabolized to form L-carnosine, an anti-glycating agent and oxidative stress reducer. When used with SCMC, NAC provides “sustained” action, SCMC is a eye lubricant and muco-adhesive provides temporary relief from burning and discomfort due to the eye’s dryness and acts as a protectant against further irritation.

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Cats and Dogs

A healthy liver produces glutathione, a natural anti-oxidant that neutralises free radicals. However, during oxidative stress, when there is an imbalance between free radicals and the levels of antioxidants in the body, there is injury and damage to liver cells. Lisybin is an advanced liver support formula that combines the anti-oxidant properties of 2 potent ingredients – S-Adenosyl Methionine & Silybin as Silybin – Phosphatidyl choline complex (SPC complex) that help in increasing glutathione levels. LISYBIN is indicated in the maintenance, improvement and protection of liver function in dogs and cats. Lisybin increases liver glutathione levels which helps in cell repair and regeneration and protecting liver cells from cell death. LISYBIN is formulated with World’s best ingredients and offers dosing convenience and accuracy

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Cats and Dogs

Kidney disease is a silent killer in dogs & cats. In older population, as many as 10% of dogs and 35% cats have chronic kidney disease. Kynetra is a kidney health support formula that contains proven Chinese herbs and vitamins that help to maintain and support kidney function. has potential to slow down the progression of kidney disease. Kynetra contains scientifically proven Chinese herbs, Rehmannia glutinosa, Astragalus, Cordycepsus sinensis, is indicated for AKI – Acute Kidney Injury & Chronic CKD Conditions Slows down CKD Progression Supplementation is beneficial in CKD including nephropathy secondary to diabetes, and hypertension Helps in recovery from vitamin deficiency caused by CKD Has shown potential to decrease serum creatinine, increase creatine clearance Reduce proteinuria and alleviate CKD-associated complications Helps in preventing damage to nephrons from oxidative stress caused by CKD. Improves Kidneys function by reducing excretion of proteins. Acts as reno protective.

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General Medicine

GLUTA-LIV Tablets are a nutraceutical supplement formulated to support skin health, detoxification, and overall vitality. Manufactured by Liv Bio Pharma, these tablets combine potent antioxidants and bioactive compounds designed to promote radiant skin and enhance metabolic function.​ 🔹 Key Ingredients and Their Benefits Ingredient Benefit Liposomal Glutathione Master antioxidant that supports liver detoxification and promotes skin radiance. Liposomal Vitamin C Enhances immunity, aids collagen production, and boosts antioxidant capacity. Alpha Lipoic Acid Protects cells from oxidative damage and supports metabolic health. Grapeseed Extract Rich in polyphenols, it supports cardiovascular health and combats oxidative stress. Astaxanthin A powerful carotenoid that supports skin health, reduces inflammation, and enhances immunity. ✅ Common Uses Condition Use of GLUTA-LIV Tablets Skin Health & Anti-Aging Promotes youthful, radiant skin and reduces signs of aging. Detoxification Supports liver detoxification and protects against toxins. Immune System Support Strengthens the body’s natural defenses against illnesses. Liver Health Aids in managing liver cirrhosis and liver damage from conditions like HIV/HCV coinfections. Antioxidant Defense Provides robust protection against free radical damage. 💊 Dosage and Administration Dosage: Take one tablet twice daily with food or as directed by your healthcare provider. Administration: Swallow the tablet whole; do not chew or crush. Consistency: For best results, use consistently as part of your daily routine.​ Arka Health ⚠️ Precautions and Side Effects Common Side Effects: Gastrointestinal discomfort such as nausea or bloating may occur. Precautions: Consult a healthcare professional before use, especially if you are pregnant, breastfeeding, or have any underlying health conditions. Drug Interactions: Berberine may interact with certain medications; consult your doctor if you are on other treatments.​ Liv Bio Pharma ✅ Summary Condition Use of GLUTA-LIV Tablets Skin Health & Anti-Aging Promotes youthful, radiant skin and reduces signs of aging. Detoxification Supports liver detoxification and protects against toxins. Immune System Support Strengthens the body’s natural defenses against illnesses. Liver Health Aids in managing liver cirrhosis and liver damage from conditions like HIV/HCV coinfections. Antioxidant Defense Provides robust protection against free radical damage.

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